Clinical trials: Personality Disorder, Borderline
Borderline Personality Disorder
The Influence of Treatment Format on Schema Therapy for Borderline Personality Disorder
The goal of this clinical trial is to compare etc. in patients with borderline personality disorder pure individual schema therapy to combined individual-group schema therapy.
- Trial name
- IST-IGST (NCT05986552)
- Testing
- Individual Schema Therapy (IST), Individual-Group Schema Therapy (IGST)
- Where
- 3 sites in Netherlands
- Volunteers
- 132 people
- Sponsor
- University of Amsterdam
Major Depressive Disorder (MDD), Borderline Personality Disorders
Home-Based tDCS for Depression in BPD
The present study aims to assess the feasibility of home-based tDCS in remote and urban areas (primary objective). The secondary aim is to obtain a preliminary assessment of the efficacy of 14 home-based tDCS sessions in reducing…
- Trial name
- TENTADIS (NCT06972368)
- Testing
- tDCS, Treatment as Usual (TAU), Psychoeducation
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Borderline Personality Disorder
Study to Test the Efficacy and Safety of Vafidemstat in Adult Borderline Personality Disorder Population
PORTICO is a Phase IIb study to evaluate the efficacy and safety of vafidemstat in an adult borderline personality disorder (BPD) population.
- Trial name
- NCT04932291
- Testing
- vafidemstat
- Where
- 21 sites in United States, Bulgaria and 3 more
- Volunteers
- 211 people
- Sponsor
- Oryzon Genomics S.A.
Borderline Personality Disorder
Neurofeedback for Borderline Personality Disorder
The goal of this study is to evaluate whether rtfMRI-nf training to increase the amygdala response to positive memories may serve as an intervention for borderline personality disorder.
- Trial name
- NCT05398627
- Testing
- Amygdala Neurofeedback
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Kymberly Young
Emotionally Unstable Personality Disorder, Borderline Type
Empathy Anomalies in Emotionally Unstable (Borderline) Personality Disorder
Emotionally unstable (borderline) personality disorder (BPD) is characterised by changeable and extreme emotions and difficulty maintaining relationships. It is often associated with self-harm.
- Trial name
- NCT05381649
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- University of Edinburgh
Borderline Personality Disorder, Relatives
PEGASUS - Improving Treatment for Patients With Emotionally Unstable Personality Disorder
The purpose of the PEGASUS study is to conduct a pilot trial to test the feasibility and acceptability of the PEGASUS intervention, adding a case manager and family-based interventions meetings to the existing psychiatric…
- Trial name
- NCT06563466
- Testing
- The experimental intervention PEGASUS, Treatment as usual
- Where
- Denmark
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group
ADOLESCENTS IMAGING USING fMRI: Feasibility Study
Impaired social cognition and cognitive control associated with borderline personality disorder (BPD) remain less explored. Recent Franco-Canadian study, has shown the feasibility of a neuroimaging tests in Quebec adolescents…
- Conditions
- Diagnosis of BPD Based on the DIB-R Clinical Interview for the BPD Group, Diagnosis of ADHD Using the KSADS-PL for the ADHD Group, Absence of Pathology on the CBCL and Ab-DIB for the Healthy Control Group, All Participants Were Euthymic at the Time of Task Administration
- Trial name
- ADO IMAGE (NCT07540429)
- Testing
- functional magnetic resonance imaging (fMRI)
- Where
- France
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Etablissement Public de la Sante Mentale de la Somme
Borderline Personality Disorder
Testing Interventions for Borderline Personality Disorder.
Borderline personality disorder (BPD) is a life-threatening, costly public health crisis affecting ~1-3% of North Americans, with 10% dying by suicide and annual healthcare costs of ~$63k (Canadian Dollars)/patient.
- Trial name
- NCT06458933
- Testing
- Sage, Supportive Individual Psychotherapy
- Where
- Canada
- Volunteers
- 304 people
- Sponsor
- York University
Borderline Personality Disorder
DBT for Chronically Self-harming Individuals With BPD: Evaluating the Clinical & Cost Effectiveness of a 6 mo. Treatment
Standard one-year dialectical behaviour therapy (DBT), which has four components, is an effective treatment for people with borderline personality disorder.
- Trial name
- FASTER-DBT (NCT02387736)
- Testing
- Dialectical Behaviour Therapy-6 months, Dialectical Behaviour Therapy-12 months
- Where
- 2 sites in Canada
- Volunteers
- 240 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder (BPD)
Cortical Plasticity of the Tactile Mirror System in Borderline Personality Disorder
People with borderline personality disorder (BPD) show alterations in the empathic abilities, which may involve the functioning of the mirror neuron system in the somatosensory domain.
- Trial name
- SG2019-EXP2 (NCT06702215)
- Testing
- Cross-modal paired associative stimulation (cm-PAS) protocol
- Where
- Italy
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder
Pilot Study on Auricular Acupuncture in Hospitalized Adults With Borderline Personality Disorder
The goal of this pilot study is to evaluate the feasibility and preliminary effectiveness of a brief auricular acupuncture program delivered by mental health nurses as a complementary therapy for adults hospitalized with…
- Trial name
- ACUPSY (NCT07476300)
- Testing
- Auricular acupuncture program based on the N.A.D.A. protocol
- Where
- Switzerland
- Volunteers
- 15 people
- Sponsor
- Jenny Gentizon
Borderline Personality Disorder (BPD)
Researching the Effectiveness of a Alivis, a Digital Health Application for Borderline Personality Disorder
This randomized controlled trial (RCT) with 470 patients diagnosed with Borderline Personality Disorder (BPD) aims to investigate the effectiveness of the unguided digital therapeutic alivis for patients with BPD as defined in…
- Trial name
- REVALDI-BPD (NCT06601907)
- Testing
- alivis
- Where
- Germany
- Volunteers
- 286 people
- Sponsor
- Gaia AG
Borderline Personality Disorder, Stress (Psychology)
Stress Autism Mate (SAM) App for Stress Management in Adults With Borderline Personality Disorder Traits
The goal of this intervention study is to learn whether a stress management app (Stress Autism Mate, SAM) can help reduce stress and support coping in adults with borderline personality disorder traits receiving outpatient mental…
- Conditions
- Borderline Personality Disorder, Stress (Psychology), Perceived Stress
- Trial name
- NCT07464301
- Testing
- Mobile Application for Stress Monitoring and Coping
- Where
- Netherlands
- Volunteers
- 16 people
- Sponsor
- GGZ Centraal
Borderline Personality Disorder (BPD)
The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy In Patients With Borderline Personality Disorder: A Study on Therapeutic Alliance, Depression, Cognitive Function, Impulsivity, Suicide Risk, BDNF Levels, NFkB Levels, SOD Levels
In the context of therapy for Borderline Personality Disorder, our department had conduct a study titled "The Effectiveness of Dialectical Behavioral Group Psychotherapy Compared to Supportive Individual Psychotherapy in Patients…
- Trial name
- DBT BPD (NCT07449104)
- Testing
- DBT group psychotherapy, Supportive Psychotherapy
- Where
- Indonesia
- Volunteers
- 66 people
- Sponsor
- Natalia Dewi Wardani, MD
Mentalisation, Mentalization
Mentalization-Based Therpay With Older Adults
The investigators would like to find out if Mentalization-Based Therapy (MBT) is effective for people aged 60+ who struggle in relationships.
- Conditions
- Mentalisation, Mentalization, Later Life, Older Adults
- Trial name
- NCT07065071
- Testing
- Mentalization-Based Therapy
- Where
- United Kingdom
- Volunteers
- 3 people
- Sponsor
- University of Nottingham
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Borderline Personality Disorder
Effectiveness of EMDR in Borderline Personality Disorder
Borderline personality disorder (BPD) is a severe mental disorder characterized by four major symptomatological domains: interpersonal instability, perceptive and identity disorders, emotional and behavioural dysregulation.
- Trial name
- EMBODIER (NCT06493708)
- Testing
- Trauma focused psychotherapy: EMDR
- Where
- Italy
- Volunteers
- 56 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Borderline Personality Disorder BPD
Characterization of the Neural Bases of Mental Imagery in Individuals With Borderline Personality Disorder: An EEG Study
Borderline Personality Disorder (BPD) involves altered social cognition, notably dysfunctional processing of cues signaling potential social exclusion and heightened social pain.
- Trial name
- BABO (NCT07428200)
- Testing
- 2 Tasks : - stop signal reaction time and Cyberball then ill out an evaluation form
- Where
- France
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Adolescent - Emotional Problem, Personality Disorders in Adolescence
Representations of the Body's Interior in Adolescence
Representations of the inner body in adolescence: developmental characteristics and specificities in borderline personality disorders.
- Conditions
- Adolescent - Emotional Problem, Personality Disorders in Adolescence, Body Representation, Borderline Personality Disorder
- Trial name
- RICA (NCT07407764)
- Testing
- Drawing of the inside of the body, interviews and questionnaires.
- Volunteers
- healthy volunteers welcome
- Sponsor
- Centre Hospitalier Intercommunal Creteil
Borderline Personality Disorder (BPD)
Brief Psychological Intervention for Suicidal Patients With Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT06675461
- Testing
- Gold Card Intervention, Treatment as usual
- Where
- Canada
- Volunteers
- 180 people
- Sponsor
- Centre for Addiction and Mental Health