Clinical trials: Personality Disorder, Borderline
Borderline Personality Disorder
Outcomes of Mentalization-Based Treatment for Borderline Personality Disorder
The effects of a psychological treatment, Mentalization-Based Treatment, was studied using a research protocol with patients with mood swings and impulsive behavior (borderline personality disorder).
- Trial name
- NCT03295838
- Testing
- Mentalization-based treatment
- Volunteers
- 75 people
- Sponsor
- Karolinska Institutet
Borderline Personality Disorder
Botulinum Toxin A for Emotional Stabilization in Borderline Personality Disorder (BPD)
The main objective of the trial is to test whether a single application of botulinum toxin A into the glabellar region will lead to emotional stabilization in borderline personality disorder through paralysis of facial…
- Trial name
- BTX-BPD (NCT02728778)
- Testing
- incobotulinumtoxin A, Acupuncture
- Where
- 2 sites in Germany
- Volunteers
- 54 people
- Sponsor
- Hannover Medical School
Child's Internalizing and Externalizing Problems
A Mentalization-based Intervention for Children of Parent(s) With Borderline Personality Disorder
Background and study aims? Parents with borderline personality disorder (BPD) can present parenting difficulties such as expressions of hostility, low sensitivity, and overprotection.
- Trial name
- NCT06050486
- Testing
- Mentalization-based treatment for children (MBT-C)
- Where
- Portugal
- Volunteers
- 8 people
- Sponsor
- University of Minho
Borderline Personality Disorder, Suicide and Self-harm
Trial of a Brief Psychological Intervention for Suicidal Patients with Borderline Personality Disorder in the Emergency Department
When in crisis, people with borderline personality disorder (BPD) frequently seek care in emergency departments (EDs) often presenting with suicide and self-harm behaviour.
- Trial name
- NCT04779099
- Testing
- Brief 4-session intervention for borderline personality disorder, Treatment as usual
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Centre for Addiction and Mental Health
Borderline Personality Disorder, Major Depression
Dorsomedial rTMS For Depression In Borderline Personality Disorder
This randomized trial with a crossover design will examine the efficacy of rTMS targeting the dorsomedial prefrontal cortex as a treatment for medication-resistant major depression in patients meeting diagnostic criteria for…
- Trial name
- rTMS (NCT03472638)
- Testing
- Dorsomedial prefrontal rTMS
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- University Health Network, Toronto
Depressive Disorder, Major, Borderline Personality Disorder
Treatment of Acute Mood Depressive Episode in Borderline Personality Disorder With rTMS
This study evaluates the antidepressant effects of an accelerated schedule of theta-burst stimulation, termed accelerated intermittent theta-burst stimulation (aiTBS), in individuals with borderline personality disorder (BPD) or…
- Trial name
- NCT04870255
- Testing
- Left Dorsolateral Prefrontal Cortex (L-DLPFC), Dorsomedial Prefrontal Cortex (DMPFC)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Stanford University
Personality Disorders, Borderline Personality Disorder
Evaluation of AIT Study
Specialized treatment of personality disorders (PD) in youth has been neglected for a long time, because these disorders were not diagnosed before the age of 18.
- Trial name
- NCT02518906
- Testing
- Adolescent Identity Treatment, DBT-A
- Where
- 3 sites in Chile, Germany and 1 more
- Volunteers
- 60 people
- Sponsor
- Klaus Schmeck
Borderline Personality Disorder, Non-suicidal Self-injury (NSSI)
ERGT for Women Engaging in NSSI - an Effectiveness Study
The primary aim is to investigate the effectiveness of Emotion Regulation Group Therapy (ERGT) for women who self-harm in ordinary psychiatric outpatient health care.
- Trial name
- NCT01986257
- Testing
- Emotion Regulation Group Therapy (ERGT).
- Where
- Sweden
- Volunteers
- 97 people
- Sponsor
- Karolinska Institutet
Borderline Personality Disorder
Measuring the Impact of Real Time fMRI Neurofeedback in Borderline Personality Disorder
This study will test the impacts of real time fMRI neurofeedback in patients with Borderline Personality Disorder. This is a pilot study in a small number of people enrolled in clinical programs at Yale New Haven Hospital.
- Trial name
- NCT04306341
- Testing
- real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Yale University
Borderline Personality Disorder, Psychotherapy
Impact of Therapeutic Alliance on Dropout in a Naturalistic Sample of Patients With Borderline Pathology Receiving Residential DBT
Participants with Borderline pathology (≥ 3 DSM-IV-criteria) receiving an inpatient Dialectical Behavior Therapy (DBT) program completed a quality assurance questionnaire set assessing demographic information and pretreatment…
- Conditions
- Borderline Personality Disorder, Psychotherapy, Dropout
- Trial name
- DBT_dropout2 (NCT05289583)
- Testing
- Dialectical Behavior Therapy
- Where
- Germany
- Volunteers
- 44 people
- Sponsor
- Evangelisches Krankenhaus Bielefeld gGmbH
Infusion of Ketamine in Severe Borderline Personality Disorder, Borderline Personality Disorder (BPD)
Ketamine Infusion for Symptomatic Improvement in Severe Borderline Personality Disorder
The main objective of this pilot study is to evaluate at D9 the evolution of BPD symptoms' intensity(scale BSL-23) in severe BPD patients, after two Ketamine infusions (0.5mg/kg at H0 and H24).
- Trial name
- BorderKET (NCT07099534)
- Testing
- IV Ketamine (0.5 mg/kg) Infusion - Two Doses Administered 24 Hours Apart for Severe Borderline Personality Disorder
- Where
- France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Toulouse
Borderline Personality Disorder
Delving Into Borderline Personality Disorder Clinical Trial Experiences
Taking part in medical study usually favors a particular demographic group. But there is limited research available to explain what trial attributes affect the completion of these specific demographic groups.
- Trial name
- NCT05989529
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Power Life Sciences Inc.
Borderline Personality Disorder (BPD)
Researching the Effectiveness of a Alivis, a Digital Health Application for Borderline Personality Disorder
This randomized controlled trial (RCT) with 470 patients diagnosed with Borderline Personality Disorder (BPD) aims to investigate the effectiveness of the unguided digital therapeutic alivis for patients with BPD as defined in…
- Trial name
- REVALDI-BPD (NCT06601907)
- Testing
- alivis
- Where
- Germany
- Volunteers
- 286 people
- Sponsor
- Gaia AG
Opiate Addiction, Borderline Personality Disorder
Evaluation of DBT Compared to Drug Counseling for Opiate Addicts
The purpose of this study is to compare a one year treatment program of Dialectical Behavior Therapy (DBT) + suboxone for opiate addicted individuals meeting criteria for borderline personality disorder (BPD) to a one year…
- Trial name
- NCT00117741
- Testing
- Dialectical Behavior Therapy, Drug Counseling
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- University of Washington
Borderline Personality Disorder
DBT in Borderline Personality Disorder
Subjects will receive a 6-month course of DBT, consisting of one 90-minute group and one 60-minute individual session per week as well as telephone availability of the individual therapist.
- Trial name
- NCT00252031
- Testing
- Dialectical Behavioral Therapy
- Where
- United States
- Sponsor
- Bronx VA Medical Center
Borderline Personality Disorder
Evaluation of the HBDL Coil Transcranial Magnetic Stimulation (TMS) Device - Feasibility Study for the Treatment of Borderline Personality Disorder
This is an open study.approximately 20 patients diagnosed with Borderline Personality Disorder (in case patient is under drug treatment, treatment should be stable within the prior 4 weeks before study entry).Starting from the…
- Trial name
- NCT01683136
- Testing
- HBDL-coil Repetitive Deep Transcranial magnetic stimulation (rdTMS)
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- Shalvata Mental Health Center
Borderline Personality Disorder
Effectiveness of a 24 Hour Phone Line on the Rate of Suicide Attempts in Borderline Patients
This randomized multicentric clinical trial assesses the effectiveness of 24 hour phone line on the rate of suicide attempts and self-injurious behaviors in borderline patients.
- Trial name
- NCT00603421
- Testing
- 24 hour phone line, treatment as usual
- Where
- 2 sites in France
- Volunteers
- 318 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Borderline Personality Disorder
A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder
This study is open to adults with borderline personality disorder. The purpose of this study is to find out whether a medicine called BI 1358894 helps to reduce symptoms in people with borderline personality disorder.
- Trial name
- NCT04566601
- Testing
- BI 1358894
- Where
- 67 sites in United States, Argentina and 13 more
- Volunteers
- 390 people
- Sponsor
- Boehringer Ingelheim
Borderline Personality Disorder
Biomarkers of Change in BPD After Metacognitive Interpersonal Therapy-standard Approach
The present randomised clinical trial aims to assess the clinical and neurobiological changes following Metacognitive Interpersonal Therapy -standard approach (MIT-SA) compared with Clinical Structured Treatment (CST) derived…
- Trial name
- CLIMAMITHE (NCT02370316)
- Testing
- Metacognitive Interpersonal Therapy (MIT-SA), Clinical Structured Treatment
- Where
- Italy
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- IRCCS Centro San Giovanni di Dio Fatebenefratelli
Borderline Personality Disorder, Posttraumatic Stress Disorder
FKBP5 Methylation and Childhood Emotional Abuse in Complex Posttraumatic Stress Disorder: Investigating the Relationship and Its Predictive Role in Therapy Outcome
The aim of this study is to investigate the role FKBP5 DNA methylation levels in patients suffering from complex posttraumatic stress disorder, who participated in a 12-weeks disorder-specific DBT-PTSD inpatient treatment.
- Trial name
- NCT06433843
- Testing
- Dialectical behavioral therapy for the treatment of posttraumatic stress disorder (DBT-PTSD)
- Where
- Germany
- Volunteers
- 29 people
- Sponsor
- University Hospital Tuebingen