Clinical trials: Persons With Psychiatric Disorders
Subthreshold Depression, Depressive Symptoms
Evaluation of Efficacy of Lycium Barbarum Polysaccharide in People With Subthreshold Depression
Lycium barbarum, a traditional Chinese herbal medicine, is a commonly used herb in the traditional Chinese pharmacopoeia . Its main active ingredient, lycium barbarum polysaccharide (LBP), is reported to have neuroprotective…
- Conditions
- Subthreshold Depression, Depressive Symptoms, Anxious Symptoms
- Trial name
- NCT04032795
- Testing
- Lycium barbarum polysaccharide
- Where
- China
- Volunteers
- 172 people
- Sponsor
- Guangzhou Psychiatric Hospital
Cognitive Impairment
An Intervention Study to Reduce Drug-related Problems and Readmissions Among Old People With Dementia
The aim of this randomized controlled study is to investigate if medication reviews performed by a clinical pharmacist as part of a ward team can reduce drug related problems and reduce readmissions to hospital among elderly…
- Trial name
- NCT01504672
- Testing
- Medication review
- Where
- 2 sites in Sweden
- Volunteers
- 460 people
- Sponsor
- Umeå University
Frontotemporal Dementia, Dementia
Care of Persons With Dementia in Their Environments (COPE) in Programs of All-Inclusive Care of the Elderly (PACE)
The protocol is organized into three Phases - In Phase I an online training program will be developed in "Care of Persons with Dementia in their Environments" (COPE) -an evidence-based bio-behavioral dementia program -using…
- Conditions
- Frontotemporal Dementia, Dementia, Multi-Infarct Dementia, Vascular Dementia
- Trial name
- NCT04165213
- Testing
- Care of Older Persons in their Environment (COPE) online module training
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Insomnia
Do People With Insomnia Sleep Better After Psychological Treatment?
The principal aim of the study is to evaluate if CBT for insomnia is associated with improvement in the PSG sleep of patients treated in primary care.
- Trial name
- NCT00170391
- Testing
- Quarter of an Hour rule
- Where
- United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- NHS Greater Glasgow and Clyde
Anxiety Disorder, Cancer
MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer
This is a pilot study intended to find out if 3,4-methylenedioxymethamphetamine (MDMA) is safe and can help people with advanced stage cancer and anxiety arising from the cancer diagnosis.
- Trial name
- NCT00252174
- Testing
- Stage 1 Active Methylenedioxymethamphetamine, Stage 1 Low dose Methylenedioxymethamphetamine, Psychotherapy
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Brigham and Women's Hospital
Frontotemporal Dementia, Alzheimer Disease
Music, Social Attention, and Dementia
This is an exploratory mixed-methods control-treatment study to evaluate if participation in rhythmic musical activities improves social attention and connectedness in individuals living with mild to moderate bvFTD and AD, and…
- Trial name
- NCT06768996
- Testing
- Synchronous Rhythm Production, Solo Rhythm Production
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Dementia, Mild Cognitive Impairment
In-Home Technology for Caregivers of People With Dementia and Mild Cognitive Impairment
This study aims to develop and evaluate new in-home supportive technology that is designed to alleviate anxiety, burden, and loneliness in spousal and familial caregivers of individuals with Alzheimer's disease, other dementias…
- Conditions
- Dementia, Mild Cognitive Impairment, Alzheimer Disease
- Trial name
- NCT04206670
- Testing
- In-Home Technology System and Questionnaires, Waiting Control In-Home Technology System and Questionnaires
- Where
- United States
- Volunteers
- 216 people, healthy volunteers welcome
- Sponsor
- University of California, Berkeley
Schizophrenia
Measurement of Activity Participation for Persons With Schizophrenia Living in the Community
The purpose of the study is to develop a questionnaire on community occupational participation for persons with schizophrenia living in the community.
- Trial name
- NCT00172731
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
Geriatric İndividual Health
Group-based and Dual-task Focused Otago Exercises in Geriatric Individuals With Kinesiophobia
The aim of our study was to investigate the effects of group-based and dual-task focused otago exercises on kinesiophobia, musculoskeletal system and psychosocial status in geriatric individuals with kinesiophobia.
- Trial name
- NCT06577740
- Testing
- Otago Exercise, Dual Task Focused Otago Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Hypertension, Diabetes
Facilitated Transitions From Postpartum to Primary Care Coordination for People With Chronic Conditions
The lack of postpartum primary care coordination is a missed opportunity to increase primary care engagement and manage chronic conditions early in life, especially for the >30% of pregnant people who have or are at risk for…
- Conditions
- Hypertension, Diabetes, Postpartum, Pregnancy
- Trial name
- NCT06557005
- Testing
- Facilitated Transition to Primary Care
- Where
- United States
- Volunteers
- 1,320 people
- Sponsor
- Massachusetts General Hospital
Chronic Obstructive Pulmonary Disease
Evaluation in Individuals with COPD and Asymptomatic Individuals
The literature does not provide sufficient information on the evaluation of frailty, handgrip strength, physical activity, kinesiophobia, and fatigue in elderly individuals with Chronic Obstructive Pulmonary Disease and…
- Trial name
- NCT06077357
- Testing
- MMSE Test, PASE Test, The PRISMA-7 Frailty Scale
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
First Episode Psychosis, Psychosis
ED to EPI: Using SMS to Improve the Transition From the Emergency Department to Early Psychosis Intervention
Psychosis is a disabling condition that typically has its onset in adolescence and early adulthood. Many young people with psychosis have difficulty navigating services or are reluctant to engage in treatment until their illness…
- Conditions
- First Episode Psychosis, Psychosis, Psychotic Episode, Psychoses, Affective
- Trial name
- NCT04298450
- Testing
- Active SMS Intervention
- Where
- Canada
- Volunteers
- 186 people
- Sponsor
- Centre for Addiction and Mental Health
Schizophrenia, Metabolic Syndrome X
Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes
This study will evaluate the effectiveness of ziprasidone treatment versus treatment with a standard atypical antipsychotic drug in improving insulin sensitivity and reducing excess abdominal fat storage in people with…
- Conditions
- Schizophrenia, Metabolic Syndrome X, Insulin Resistance
- Trial name
- NCT00338949
- Testing
- Switch, Control
- Where
- United States
- Volunteers
- 77 people
- Sponsor
- Veterans Medical Research Foundation
Schizophrenia, Bipolar Disorder
Assessment of the Effectiveness of the NECT Program
Self-stigma refers to the transformation process wherein a person's previously held social identity is progressively replaced by a devalued and stigmatized view of oneself termed "illness identity".
- Conditions
- Schizophrenia, Bipolar Disorder, Borderline Personality Disorder, Social Function
- Trial name
- NECT (NCT03972735)
- Testing
- Psychiatric interview, Clinical, diagnostic and functional evaluation, neuropsychological assessment
- Where
- 11 sites in France, Switzerland
- Volunteers
- 120 people
- Sponsor
- Hospital Center Alpes-Isère
Depression
Effectiveness of a Technology Assisted Behavioral Intervention in Assisting People With Major Depressive Disorder
This study will develop and evaluate the effectiveness of a technology-assisted behavioral intervention, consisting of Internet-based cognitive behavioral therapy combined with telephone and email support, in reducing depressive…
- Trial name
- NCT00719979
- Testing
- Behavioral intervention (iCBT + TeleCoach), Internet-based cognitive behavioral therapy (I-CBT), Treatment as usual / Wait-list control
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- Northwestern University
Social Stigma, Virtual Reality
Effects of Virtual Reality Software on Levels of Stigma Towards People With Mental Illness.
The purpose of the research is to contribute to the reduction of stigma among university students among people with serious psychiatric illnesses and to improve future educational processes focused on the social inclusion of…
- Trial name
- NCT05393596
- Testing
- Virtual Reality Software Intervention
- Where
- Chile
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Universidad del Desarrollo
Renal Insufficiency,Chronic, Dietary Intake Patterns
Strategies for Proactive Health in People With Kidney Function Decline
This prospective cohort study aims to investigate how kidney function decline affects multiple body systems and how personalized nutrition can help maintain health and slow disease progression.
- Conditions
- Renal Insufficiency,Chronic, Dietary Intake Patterns, Malnutrition, Frailty
- Trial name
- NCT07245186
- Where
- China
- Volunteers
- 1,800 people
- Sponsor
- Huashan Hospital
Chronic Low Back Pain (CLBP), Chronic Insomnia
Studying the Neurobiological Mechanisms of Non-specific Chronic Low Back Pain and Chronic Insomnia: a Four-group Cross-sectional Study
This study is a part of a larger project aiming to evaluate the neurobiological mechanisms underlying the relationship between sleep and pain in people with non-specific chronic low back pain.
- Conditions
- Chronic Low Back Pain (CLBP), Chronic Insomnia, Neuroinflammation
- Trial name
- SY-NAPS-CS (NCT06973837)
- Testing
- Real-life monitoring, experimental pain testing, brain imaging, blood and stool sampling.
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Mild Cognitive Impairment, Alzheimer Disease
A Feasiblity Study of Green Activity Program for People Living With Memory Challenges
The purpose of this study is to test the Green Activity Program that was designed with people living with memory challenges and their study partners to see if it can be done and if they enjoy the program.
- Conditions
- Mild Cognitive Impairment, Alzheimer Disease, Subjective Cognitive Decline (SCD)
- Trial name
- GAP (NCT06403345)
- Testing
- Green Activity Program
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Indiana University
Surface and Deep Dyspareunia
Physiotherapeutic Approach to Superficial and Deep Dyspareunia in Women With Chronic Pelvic Pain: Comparison Between In-person and Telehealth Care.
Adequate sexual function is considered an important factor in satisfaction and overall quality of life for both men and women. It is estimated 16% to 40% of women suffer from some form of sexual dysfunction, which is currently…
- Trial name
- NCT07658703
- Testing
- Face-to-face treatment, Telecare
- Where
- Brazil
- Volunteers
- 72 people
- Sponsor
- University of Sao Paulo
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