Clinical trials: Persons With Psychiatric Disorders
Anxiety, Depression
Career Management to Improve Education, Employment and Retention for People With Anxiety and Depression
The aim of the investigation is to evaluate the effectiveness and costeffectiveness of a model of supported employment (the Individual Career Management (ICM) model) designed to help people with common mental illness return to…
- Trial name
- CAREER (NCT01599481)
- Testing
- Individual Career Management (ICM), Standard Care
- Where
- United Kingdom
- Volunteers
- 261 people, healthy volunteers welcome
- Sponsor
- South London and Maudsley NHS Foundation Trust
Post-COVID-19 Syndrome, Anxiety
Connecting Breath and Mind for CYP With Long COVID
Recruitment target: Phase I: Co-design of intervention: 5 to 15 CYP aged between 12-18 years of age referred to the pan-London long COVID MDT.
- Conditions
- Post-COVID-19 Syndrome, Anxiety, Breathlessness
- Trial name
- NCT05705154
- Testing
- Psychology interventions
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Royal Brompton & Harefield NHS Foundation Trust
Schizophrenia
A Study of the Effects of Sarcosine on Symptoms and Brain Glycine Levels in People With Schizophrenia
The NMDA receptor has been identified as having a role in substance use disorders as well as in schizophrenia. One example of the former is nicotine's effect on dopaminergic activity not only by increasing the release of dopamine…
- Trial name
- Sarc (NCT00538070)
- Testing
- Sarcosine
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- Massachusetts General Hospital
Brief Psychotic Disorder, Psychosis; Episode
Effectiveness of the Individualized Metacognitive Training (EMC+) in People With Psychosis of Brief Evolution
The main aim of the study is to evaluate the effectiveness of Individualized Meta-Cognitive Training (EMC +), in people with psychosis of brief evolution on symptoms, especially on positive symptoms.
- Trial name
- NCT04429412
- Testing
- MCT+
- Volunteers
- 70 people
- Sponsor
- Fundació Sant Joan de Déu
Aphasia, Stroke
Brain-based Understanding of Individual Language Differences After Stroke
Strokes often cause a loss of communication ability, referred to as aphasia, as well as cognitive difficulties. Each stroke survivor has a unique pattern of strengths and weaknesses in communication and cognition, and a unique…
- Conditions
- Aphasia, Stroke, Alexia
- Trial name
- BUILD (NCT04991519)
- Where
- United States
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Georgetown University
Chronic Pain, Chiari Malformation
Online Acceptance and Commitment Therapy for Chronic Pain in Sample of People With Chiari Malformation
Twenty percent of US adults report chronic pain symptoms. Both psychological symptoms and sleep issues commonly co-occur with chronic pain.
- Trial name
- NCT04089670
- Testing
- Online Acceptance and Commitment Therapy Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Kent State University
Dementia, Agitation
A Music-Based Mobile App for People Living With Alzheimer's Disease and Related Dementias (ADRD)
The purpose of this pilot is to develop a mobile application that detects physiological measures of individuals with Alzheimer's disease and related dementias and triggers auto-play of personalized songs in a wearable device.
- Conditions
- Dementia, Agitation, Depressive Symptoms
- Trial name
- NCT06140342
- Testing
- Feasibility study of music-based mobile app
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Autotune Me LLC
Schizophrenia
Effect of Virtual Reality-based Therapy on Negative Symptoms in People with Schizophrenia
A randomised, controlled, double-blind clinical trial will be carried out to evaluate the effectiveness of a VR assisted treatment for negative symptoms in people with schizophrenia.
- Trial name
- VR-SCHIZO (NCT06588270)
- Testing
- Virtual Reality Therapy for the Negative Symptoms of Schizophrenia
- Where
- Chile
- Volunteers
- 102 people
- Sponsor
- Hospital de la Florida Dra. Eloiza Diaz
Dementia
Digital Reminiscence for People With Dementia
The purpose of this study is to explore the feasibility and acceptability of a digital reminiscence therapy (DRT) intervention for people with dementia (PwD). The objectives of this study include: 1.
- Trial name
- DTR (NCT03429686)
- Testing
- DRT Intervention
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
Hearing Loss, Cognitive Impairment, Mild
ENACT Program on Auditory Perception and Function, Cognitive Function and Health-related Quality of Life
Although previous studies indicated that tackling hearing loss may have a secondary benefit in improving cognitive function and delaying the onset of dementia, a more integrated care approach to optimize both hearing and…
- Trial name
- NCT06955494
- Testing
- Empowerment Network for Auditory-Cognitive Training (ENACT) Program, Usual Care
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- The University of Hong Kong
Frontotemporal Dementia, Frontotemporal Degeneration
Voices Of Individuals: Challenges and Experiences Of bvFTD
The VOICE Of bvFTD study is a telephone interview research study about life with or at risk for behavioral variant frontotemporal dementia (bvFTD).
- Conditions
- Frontotemporal Dementia, Frontotemporal Degeneration, Frontotemporal Dementia, Behavioral Variant, FTD
- Trial name
- NCT04060082
- Testing
- Telephone Interview
- Where
- 3 sites in United States
- Volunteers
- 26 people
- Sponsor
- University of Pennsylvania
Dementia
An In-home Respite Care Program to Support Informal Caregivers of People With Dementia
The general objective of this quasi-experimental study is to assess the effectiveness of an in-home respite care program compared to a control group not receiving the same type of in-home respite on the well-being of the…
- Trial name
- NCT02630446
- Testing
- in-home respite care program
- Where
- Belgium
- Volunteers
- 355 people
- Sponsor
- University Ghent
Randomized Controlled Trial
Exploring the Effect of Baduanjin on the Metabolic Parameters and Body Mass Index of People With Schizophrenia
Baduanjin seems to be effective for improving body mass index and fasting sugar in male individuals with schizophrenia. Aim This study was to explore the effect of Baduanjin on the five metabolic parameters and body mass index in…
- Trial name
- NCT04069988
- Testing
- Baduanjin program
- Where
- Taiwan
- Volunteers
- 92 people
- Sponsor
- National Yang Ming Chiao Tung University
Psychosis
Supported Employment in a Swedish Context
This project aims at generating evidence of a work-rehabilitation strategy that benefits the people with severe mental illness (SMI) who want to work, increase their sense of well-being and integration in society, decrease their…
- Trial name
- NCT00960024
- Testing
- Individual Placement and Support-vocational rehabilitation, Vocational rehabilitation available
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Spinal Cord Injuries, Cognitive Decline
SCED Myokines and Cognition in SCI
Rationale: Individuals with spinal cord injury (SCI) suffer from accelerated cognitive aging. In able-bodied individuals, a vast amount of studies have shown that exercise interventions can improve cognitive function.
- Trial name
- NCT05822297
- Testing
- Neuromuscular electrical stimulation
- Where
- Netherlands
- Volunteers
- 19 people
- Sponsor
- Adelante, Centre of Expertise in Rehabilitation and Audiology
Mild Cognitive Impairment
The Effect of Vırtual Reality Application ın Elderly People With Mild Cognitive Impairment
This study was conducted to investigate the effect of virtual reality application on visual skills, perceived occupational performance and satisfaction in elderly individuals with mild cognitive impairment.
- Trial name
- NCT06500650
- Testing
- Person-centred Occupational Therapy Intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people
- Sponsor
- Saglik Bilimleri Universitesi
Caregiver Resilience and Stress
Emergency Preparedness for Caregivers of Persons With Dementia: Disaster PrepWise
Individuals with dementia and their families are especially vulnerable during a disaster as it limits caregivers' ability to continue with care due to disaster related stress and reduced access to resources and support.
- Trial name
- DPW-Caregiver (NCT05619263)
- Testing
- Disaster PrepWise-Caregiver
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Sato Ashida
Anxiety, Stage IV Melanoma
Psilocybin-Assisted Psychotherapy for Anxiety in People With Stage IV Melanoma
This study is to find out about whether two sessions of psilocybin-assisted psychotherapy are safe and will help people who are anxious as a result of having stage IV melanoma and will involve two sessions of psychotherapy…
- Trial name
- NCT00979693
- Testing
- psilocybin
- Where
- United States
- Sponsor
- Multidisciplinary Association for Psychedelic Studies
Smoking Cessation
Novel Smoking Cessation Drug for Schizophrenia
The investigators will evaluate effects of a novel drug that improves nicotinergic receptor function vs. placebo on short-term smoking abstinence in smokers with schizophrenia who have a high interest in quitting.
- Trial name
- TRENDS (NCT02230384)
- Testing
- Active JNJ Drug
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- K.N. Roy Chengappa
Alzheimer Disease
A Family-centered Intervention for Acutely-ill Persons With Dementia
This study will address the effectiveness of Family-centered Function Focused Care (Fam-FFC). Fam-FFC is a theoretically-based approach to care in which family caregivers partner with nurses to prevent functional decline and…
- Trial name
- NCT03046121
- Testing
- Family-centered Function-focused Care (Fam-FFC)
- Where
- 3 sites in United States
- Volunteers
- 461 people
- Sponsor
- Penn State University
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