Clinical trials: Persons With Psychiatric Disorders
HIV, Opioid Dependence
Study of Integrating Antiretroviral Therapy With Methadone Treatment for People Who Inject Drugs
To improve ART initiation among people who inject drugs, the investigators propose to develop and pilot a multi-component Integrated Methadone and Antiretroviral Therapy strategy (IMAT) in Dar es Salaam, Tanzania.
- Trial name
- IMAT (NCT02167425)
- Testing
- IMAT
- Volunteers
- 800 people
- Sponsor
- Pangaea Global AIDS Foundation
Mild Cognitive Impairment
Cognitive Intervention for Persons With Amnestic Mild Cognitive Impairment
People with mild cognitive impairment (MCI) are at a greater risk of developing dementia. Therefore, it is important to develop effective non-pharmacological interventions to facilitate their cognitive and activities of daily…
- Trial name
- NCT02785315
- Testing
- rehabilitation & remediation approach, remediation approach
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Taiwan University Hospital
Tobacco Use Disorder/Cigarette Smoking, HIV
Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial
Cigarette smoking is an important cause of illness and death among persons with HIV (PWH). This project will study the impact of adding contingency management (use of financial rewards) to receiving medications and counseling on…
- Trial name
- NCT07835555
- Testing
- nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster
- Where
- 5 sites in United States
- Volunteers
- 794 people
- Sponsor
- Yale University
Major Depressive Disorder
Early Improvement in Individual Symptoms and Response to Antidepressants in Patients With Major Depressive Disorder
Major depressive disorder (MDD) affects around 7% of the population yearly. Although effective treatments are available, only around half of all patients participating in clinical trials respond to 6 to 12 weeks of antidepressant…
- Trial name
- NCT02934035
- Testing
- Antidepressant
- Volunteers
- 10,000 people
- Sponsor
- University Medical Center Groningen
Tobacco Use Disorder, Alcohol Use Disorder
Cytisine for Smoking Cessation
The goal of this clinical trial is to evaluate the safety and effectiveness of cytisine as a smoking cessation treatment in individuals with concurrent alcohol use disorder.
- Conditions
- Tobacco Use Disorder, Alcohol Use Disorder, Smoking Cessation
- Trial name
- NCT05729243
- Testing
- Cytisine
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Centre for Addiction and Mental Health
Long Covid-19, Emotional Disorder
Effectiveness and Acceptability of the Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders in People With Long COVID-19.
This Randomized Controlled Trial (RCT) aims to assess the effectiveness and acceptability of the Unified Protocol (UP) in an online group format for the treatment of emotional disorders in adults.
- Conditions
- Long Covid-19, Emotional Disorder, Anxiety, Depression Disorders
- Trial name
- UP-LONGCOVID-R (NCT06928480)
- Testing
- Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders, Treatment as Usual (TAU)
- Where
- 2 sites in Spain
- Volunteers
- 90 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Type 1 Diabetes, Eating Disorders
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
This study aims to test the effectiveness of an evidence-based eating-disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05399446
- Testing
- Diabetes Body Project, Educational Group
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Asperger's Disorder, Asperger Disorder
QAIAx - SGI/SI Smart Health Cities: Microcity Enclave Program (Quantum SI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360; USPTO EO 9424 Assignment ID: 2101042 / ARN: REEL/FRAME: 76481/0026 - OUSD-R&E, Department of War)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum SI/SGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Multiple Sclerosis, Pelvic Floor Disorder
RedCord in Neurogenic Bowel Dysfunction in Multiple Sclerosis
The study aims to evaluate the effectiveness of Redcord treatment for neurogenic bowel dysfunction in patients with multiple sclerosis.
- Trial name
- NCT06838624
- Testing
- Redcord, Control (Standard treatment)
- Where
- Spain
- Volunteers
- 76 people
- Sponsor
- University of Castilla-La Mancha
Mild Cognitive Impairment, Dementia
Centre- Versus Home-based Exercise for MCI and Early Dementia
The study is a proof-of-concept, double-blinded randomized, parallel group trial to compare the effectiveness of centre-based and home-based physical activity in helping people with MCI and early dementia meet physical activity…
- Trial name
- CHIME (NCT02774720)
- Testing
- Centre-based exercise, Home-based exercise
- Where
- 2 sites in Canada
- Volunteers
- 44 people
- Sponsor
- University of Waterloo
Huntington's Disease
Feasibility and Acceptability of Implementing a Clinic-based Physical Activity Coaching Intervention in People With Premanifest and Early Stage HD
This study will evaluate the feasibility and acceptability of a clinic-based physical activity coaching intervention in people with pre-manifest and early stage Huntington's Disease (HD).
- Trial name
- NCT03306888
- Testing
- Physical Activity Coaching
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Teachers College, Columbia University
Mental Illness Persistent, Chronic Disease
Reverse Colocated Integrated Care Intervention Among Persons With Severe Persistent Mental Illness at US-Mexico Border
This study evaluated whether patients with severe and persistent mental illness (SPMI) who received coordinated co-located behavioral health and primary care services were more likely to improve health outcomes after 12 months…
- Conditions
- Mental Illness Persistent, Chronic Disease, Hypertension, Diabetes
- Trial name
- NCT03881657
- Testing
- Reverse Colocated Integrated Care, Usual Care
- Volunteers
- 416 people, healthy volunteers welcome
- Sponsor
- Health Resources in Action, Inc.
Nicotine Dependence, Tobacco Dependence
Adapting and Evaluating a Tobacco Use Cessation Program for People Living With HIV in Uganda and Zambia
This proposal tests the efficacy of a phone-based tobacco cessation intervention for people living with HIV (PLWH) in comparison to the standard of care (brief advice to quit) and nicotine replacement therapy (nicotine patches)…
- Trial name
- Quit4Life (NCT05487807)
- Testing
- Nicotine patch, text messaging
- Where
- 2 sites in Uganda, Zambia
- Volunteers
- 800 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Dementia, Caregiver Burden of People With Dementia
VR-based Mindfulness for Dementia Caregivers in the Home Environment (Mind-body Interventions)
To explore the feasibility, acceptability, and potential effectiveness among dementia caregivers of the mindfulness-based interventions delivered by VR technology (VR-based MBI) in improving psychological well-being and…
- Trial name
- vrmdc (NCT07103434)
- Testing
- VR Mindfulness intervention, Audio-based MBI, Waitlist control
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Psychiatric Disorder
Qualitative Study About Psychedelics Using in Psychiatric Disorders
This study is set up to better understand the current use of psychedelics in France in the general population. The present focus on individuals who have used any type of psychedelic drug in order to suppress or alleviate a…
- Trial name
- PSYCHEQUALI (NCT06014164)
- Testing
- Interview
- Where
- France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Toulouse
Dementia, Depression
A Support Program for Carers of Persons With Dementia
Dementia is one of the most common and devastating diseases in the elderly, it leads to helplessness, no cure exists and therefore care is necessary to provide.
- Trial name
- DIF2 (NCT01287767)
- Testing
- A multidimensional support program
- Where
- Norway
- Volunteers
- 230 people
- Sponsor
- Norwegian Centre for Ageing and Health
Dementia
Effects and Costs of a Day Care Centre Program Designed for People With Dementia
Attending day care centres with programs specifically designed for patients with dementia is believed to postpone admittance to nursing home as well as increase quality of life and well-being for both patients and their family…
- Trial name
- ECOD (NCT01943071)
- Testing
- Day care for patients with dementia
- Where
- Norway
- Volunteers
- 261 people
- Sponsor
- Norwegian Centre for Ageing and Health
Schizophrenia, Bipolar Disorder
A Pilot Randomised Controlled Trial of a Health Champion Intervention
This study is a pilot RCT to evaluate the effectiveness and implementation challenges of an intervention using volunteer 'Health Champions' matched with service users to support service their physical health goals.
- Conditions
- Schizophrenia, Bipolar Disorder, Major Depressive Disorder
- Trial name
- NCT04124744
- Testing
- Health Champions intervention, Control group-treatment as usual
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- King's College London
Dementia, Agitation
Doll Therapy for Agitated Elderly Dementia People
This study is designed to determine the effect of doll therapy on the levels of agitation, nutrition, and daily living activities in elderly patients with dementia and agitation.
- Trial name
- DT (NCT06578819)
- Testing
- doll therapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Karadeniz Technical University
Depression, Major Depressive Disorder
Nitrous Oxide for the Treatment of Major Depressive Disorder
The investigators are conducting a randomized controlled trial to evaluate the antidepressant effects of nitrous oxide in people with Major Depressive Disorder (MDD).
- Trial name
- NCT03869736
- Testing
- Nitrous Oxide
- Where
- 2 sites in United States, Australia
- Volunteers
- 81 people
- Sponsor
- Bayside Health
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