Clinical trials: Persons With Psychiatric Disorders
Schizophrenia
The Genetic Basis of Inherited Neurologic Deficits in People With Schizophrenia
This is a study of the genetic basis of brain dysfunction in people with schizophrenia.
- Trial name
- NCT00247637
- Where
- 7 sites in United States
- Volunteers
- 2,025 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Posttraumatic Stress Disorder
Efficacy of Internet-delivered Trauma-focused CBT for Young People With PTSD
The goal of this clinical trial is to compare therapist-guided internet delivered trauma-focused cognitive behavior therapy (CBT) to an active control condition comprising therapist-guided internet delivered cognitive behavioral…
- Trial name
- NCT06185244
- Testing
- Therapist-supported internet-delivered trauma-focused CBT, 12 weeks of therapist-supported internet-delivered psychoeducation and stress management/relaxation for both the youth and the care giver.
- Where
- Sweden
- Volunteers
- 240 people
- Sponsor
- Karolinska Institutet
Depression - Major Depressive Disorder, Insomnia
Auditory Stimulation for Insomnia and Depression
The goal of this clinical trial is to determine if alpha phase-locked auditory stimulation can improve sleep in people with insomnia and depression.
- Trial name
- NCT07553364
- Testing
- Alpha phase-locked auditory stimulation
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Huntington Disease
A Pilot Evaluation of Mindfulness-based Cognitive Therapy for People With Huntington's Disease
This is a pilot study to see whether mindfulness-based cognitive therapy, which is a type of psychological therapy, is able to improve the psychological wellbeing of people who have the gene for Huntington's disease.
- Trial name
- NCT02464293
- Testing
- Mindfulness-based cognitive therapy
- Where
- United Kingdom
- Volunteers
- 16 people
- Sponsor
- Lancaster University
Insomnia
Auriculotherapy on Older People With Insomnia
Objective To determine the optimum treatment protocol of auriculotherapy (AT) on the improvement of sleep conditions and quality of life on the elders with insomnia.
- Trial name
- NCT02970695
- Testing
- magneto-auriculotherapy (MAT), Laser auriculotherapy (LAT)
- Where
- Hong Kong
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
HIV, AIDS
Smoking Cessation for People Living With HIV/AIDS
In this proposed study with People Living with HIV/AIDS (PLWHA), we will use a stepped care model called a Sequential Multiple Assignment Randomized Trial (SMART) to examine the efficacy of low- and high-intensity smoking…
- Conditions
- HIV, AIDS, Nicotine Dependence
- Trial name
- NCT01965405
- Testing
- Bupropion, Brief Counseling, High-magnitude prize contingency management
- Where
- United States
- Volunteers
- 165 people
- Sponsor
- Wayne State University
Family Members, Relatives
Feasibility of the 5-Step Method in the U.S.
The purpose of this study is to see if it is possible (feasible) to introduce a behavioral intervention for family members affected by a relative's misuse of drugs and/or alcohol in the United States.
- Conditions
- Family Members, Relatives, Substance-Related Disorders, Alcohol-Related Disorders
- Trial name
- NCT06565429
- Testing
- 5-Step Method Intervention
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Villanova University
Intellectual Disabilities (F70-F79), Neurologic Manifestations
Functional Skills Training for Supermarket Shopping Using NFC Technology in People With Intellectual Disabilities
The general objective of the "Compra con-Migo" project is to evaluate the impact of a technological tool based on NFC (Near Field Communication) technology on the development of cognitive and instrumental skills necessary to…
- Trial name
- NCT07659457
- Testing
- App training
- Where
- Spain
- Volunteers
- 20 people
- Sponsor
- Universidade da Coruña
Trauma, Psychological, Psychosis
A Comprehensive Third-generation Intervention for People With Psychosis and Post-traumatic Stress Symptoms
Existing data suggest that both trauma and Post-Traumatic Stress Disorder (PTSD) are very common among individuals with psychosis.
- Trial name
- IITG-PPT (NCT05619822)
- Testing
- TAU + A comprehensive third-generation intervention, TAU
- Where
- Spain
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid
Tobacco Addiction
Interventional Study on Smoking Reduction in Psychiatry
The smoking rate among people with mental disorders is higher than in the general population. Greater exposure to the harmful effects of tobacco partly explains the major inequality in life expectancy observed among people with…
- Trial name
- TABAPSY (NCT06926153)
- Testing
- TABAPSY, Usual Care
- Where
- 22 sites in France, Guadeloupe and 1 more
- Volunteers
- 6,500 people
- Sponsor
- GCS-CCOMS
Dementia Disorders, Mild Cognitive Impairment (MCI)
Multimodal Biomarkers in Individual With Cognitive Impairment and Dementia
Memory problems can range from normal aging to mild cognitive impairment (MCI) to dementia. This study looks at three ways of measuring what is happening in the brain at each of these stages: a blood test (GFAP), a brain MRI…
- Trial name
- NCT07812480
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cognitive Training, Dementia
Multi-component Cognitive Intervention for Older Adults With Mixed Cognitive Abilities
Objective: To assess the feasibility and preliminary effectiveness of an evidence-driven, pragmatic multi-component cognitive intervention with simulated everyday tasks (MCI-SET) with an inclusive group design in community…
- Conditions
- Cognitive Training, Dementia, Occupational Therapy, Aging
- Trial name
- NCT04615169
- Testing
- Multi-component cognitive intervention with simulated everyday tasks (MCI-SET)
- Where
- Taiwan
- Volunteers
- 140 people
- Sponsor
- National Cheng Kung University
Sleep Initiation and Maintenance Disorders, Depression
Self-help Smartphone-delivered Cognitive Behavioral Therapy for Insomnia in People With Depression and Insomnia
This randomized controlled trial aims to examine the effectiveness of a self-help smartphone-delivered cognitive behavioral therapy for insomnia, compared to a waitlist control, in treating people with major depression and…
- Trial name
- NCT04228146
- Testing
- Cognitive Behavioral Therapy for Insomnia, Waitlist Control
- Where
- China
- Volunteers
- 285 people
- Sponsor
- The University of Hong Kong
Dementia
The Effects of Music on ANS and Anxiety in Healthy Elderly and Persons With SCD
Subjective cognition decline (SCD) is considered as a risk factor of dementia and associates not only with further cognition deterioration but with a higher anxiety level.
- Trial name
- NCT04177160
- Testing
- Music, White noise
- Where
- Taiwan
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Mild Cognitive Impairment
Efficacy of Different Doses of Tai Chi Chuan on Cognitive Function in Persons With Mild Cognitive Impairment
To determine the relationship between the effects of different frequencies and duration of Tai Chi Chuan in dose parameters to improve cognitive function in elderly persons with mild cognitive impairment.
- Trial name
- NCT06375720
- Testing
- Lower frequency, shorter period of Tai Chi Chuan, Higher frequency, shorter period of Tai Chi Chuan, Lower frequency, longer period of Tai Chi Chuan
- Volunteers
- 350 people
- Sponsor
- Lidian Chen
Stress Disorders, Post-Traumatic
An Integrated Online Program Using Psychoeducation and Expressive Writing for People With Probable Post-traumatic Stress Disorder and Coexisting Dissociative Symptoms
Objectives: To evaluate the feasibility, acceptability, safety, and preliminary effects of an integrated online program with psychoeducation and expressive writing components for people with probable post-traumatic stress…
- Trial name
- NCT06523023
- Testing
- An integrated online program
- Where
- Hong Kong
- Volunteers
- 72 people
- Sponsor
- Chinese University of Hong Kong
Type 1 Diabetes, Eating Disorders
Multi-Site Eating Disorder Prevention Program for Type 1 Diabetes
This study aims to test the effectiveness of an evidence-based eating-disorder prevention program specifically targeted for individuals with Type 1 Diabetes (T1D) compared to an educational control group.
- Trial name
- NCT05399446
- Testing
- Diabetes Body Project, Educational Group
- Where
- 4 sites in United States, Netherlands and 1 more
- Volunteers
- 280 people
- Sponsor
- Oslo University Hospital
Schizophrenia
A Clinical Trial to Evaluate the Efficacy and Safety of SEP-363856 in Acutely Psychotic People With Schizophrenia, Followed by an Open-label Extension Phase
A clinical study to investigate the effect of 2 doses of an investigational drug in acutely psychotic adult patients with schizophrenia. The study will consist of a double-blind phase followed by an open-label extension phase.
- Trial name
- NCT04825860
- Testing
- SEP-363856 50 mg, SEP-363856 75 mg
- Where
- 54 sites in China, Japan and 2 more
- Volunteers
- 83 people
- Sponsor
- Sumitomo Pharma Co., Ltd.
Dementia, Med: Dementia
Can Value Champions Reduce Inappropriate Prescribing for People With Dementia?
The primary objective is to assess the effectiveness of training a clinician to be a 'value champion' within clinical settings to decrease the use of three classes of potentially inappropriate prescription medications (PIMs)…
- Trial name
- NCT05359679
- Testing
- Value Champion Training Program, No Intervention
- Where
- United States
- Volunteers
- 3,300 people
- Sponsor
- Kaiser Permanente
Dementia
Digital Reminiscence for People With Dementia
The purpose of this study is to explore the feasibility and acceptability of a digital reminiscence therapy (DRT) intervention for people with dementia (PwD). The objectives of this study include: 1.
- Trial name
- DTR (NCT03429686)
- Testing
- DRT Intervention
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Nottingham
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