Clinical trials: Persons With Psychiatric Disorders
PARKINSON DISEASE (Disorder), Mild Cognitive Impairment (MCI)
Dual-task Cognitive-motor Telerehabilitation in Persons With PD-MCI
Telerehabilitation is a promising tool for treating and preventing further disease progression in Parkinson's disease (PD) [1, 2].
- Trial name
- HomeFitPD (NCT07411365)
- Testing
- Dual-task Cognitive Motor Training, Cognitive Motor Training
- Where
- Germany
- Volunteers
- 42 people
- Sponsor
- University Hospital Tuebingen
Developmental Disability, Intellectual Disability
Online Learning Module to Advance Research Related to People With Disabilities
This study will measure the effects of a brief one-time eLearning intervention on researcher Knowledge, Attitudes, and Perceptions (KAP) of including people with disabilities (PWDs) in biomedical \& behavioral research.
- Conditions
- Developmental Disability, Intellectual Disability, Disability
- Trial name
- D2/R3 (NCT07220837)
- Testing
- eLearning module, Control
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Albert Einstein College of Medicine
Major Depressive Disorder, Anxiety
The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression
To measure the effects of Microbial Ecosystem Therapeutics (MET)-2 on symptoms of depression and anxiety using pre- and post-treatment scores for overall depression and anxiety
- Trial name
- NCT04602715
- Testing
- MET-2
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- NuBiyota
Mental Illness
Evaluation of a Health Promotion Intervention for Persons With Mental Illness
This pilot study evaluates an individualized health promotion program for people with mental illness receiving services at a mental health center in Keene, NH.
- Trial name
- NCT00215189
- Testing
- In SHAPE (Pilot Health Promotion Intervention)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Tourette Syndrome
Epidemiology of Assertiveness and Emotion Management Disorders in People With Tourette's Syndrome
The goal of this study is to evaluate the proportion of assertiveness difficulties in Tourette syndrome. Participants will complete several e-questionnaires (on assertiveness, Tourette severity, quality of life, self-esteem and…
- Trial name
- AFFIRMATICS (NCT06136572)
- Testing
- Rathus Assertiveness scale
- Where
- France
- Volunteers
- 350 people
- Sponsor
- University Hospital, Clermont-Ferrand
Caregivers, Caregiver Burden
Feasibility Study of Project Carer Matters for Family Caregivers of Persons With Dementia
The study uses the Reach, Effectiveness, Adoption, Implementation and Maintenance (RE-AIM) framework to assess the Carer Matters programme for dementia caregivers in Singapore.
- Conditions
- Caregivers, Caregiver Burden, Caregiver Burnout, Dementia
- Trial name
- NCT05205135
- Testing
- SHARE Programme
- Where
- Singapore
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Tan Tock Seng Hospital
Autism Spectrum Disorder, Autism
In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve…
- Trial name
- NCT06577623
- Testing
- MINDful TIME
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southwest Autism Research & Resource Center
Vestibular Diseases, Alzheimer Disease
Vestibular Physical Therapy for People With Alzheimer Disease
The purpose of this study is to assess the tolerability and preliminary efficacy of an 8-week home-based vestibular physical therapy program in people with cognitive impairment.
- Conditions
- Vestibular Diseases, Alzheimer Disease, Cognitive Impairment
- Trial name
- VPT in AD (NCT03887923)
- Testing
- Vestibular Physical Therapy
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- University of Pittsburgh
Dementia, Dementia Alzheimers
Persons With Dementia and Their Extended Family Caregivers
Immediate family members shoulder the majority of care responsibilities for persons living with dementia. However, due to various societal changes, elder care responsibilities have expanded to extended family members, including…
- Conditions
- Dementia, Dementia Alzheimers, Neuro-Degenerative Disease, Dementia of Alzheimer Type
- Trial name
- CareEx (NCT04863859)
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Karen Roberto
Psychotic Disorders
Critical Time Intervention in the Transition From Hospital to Community in People With Severe Mental Illness
This study will evaluate the effectiveness of a psychosocial treatment, Critical Time Intervention, in easing the transition from hospital to community in people with severe mental disorders.
- Trial name
- NCT00621465
- Testing
- Critical Time Intervention (CTI), Usual care
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- New York State Psychiatric Institute
Early Alzheimer's Disease
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Researchers want to know if the study treatment called MK-2214 works to slow certain changes in the brains of people with Alzheimer's disease (AD).
- Trial name
- NCT07033494
- Testing
- MK-2214
- Where
- 80 sites in United States, Argentina and 9 more
- Volunteers
- 340 people
- Sponsor
- Merck Sharp & Dohme LLC
Gram-Positive Bacterial Infections, Gram-Positive Bacteraemia
Substance Use Disorder (SUD)-Associated Infections' Treatment With Dalbavancin ENabling OUtpatient Transition
The Investigators aim to study the outcomes of serious infections due to vancomycin susceptible infections in gram-positive organisms susceptible to vancomycin in people who use drugs (PWUD).
- Conditions
- Gram-Positive Bacterial Infections, Gram-Positive Bacteraemia, Substance Use Disorders, Intravenous Substance Abuse
- Trial name
- SUDDEN-OUT (NCT04847921)
- Testing
- Dalbavancin
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Colorado, Denver
Dementia, Caregiver
Artificial Intelligence + Care Coach Intervention
The purpose of this research study is to develop and test an artificial intelligence intervention for emergency department (ED) discharge care transitions experienced by caregivers of older adults with cognitive impairment.
- Conditions
- Dementia, Caregiver, Emergency Department, Artificial Intelligence
- Trial name
- NCT05352399
- Testing
- NeuViCare application
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Yale University
Schizophrenia, Schizoaffective Disorder
Computerized Cognitive-Behavioral Therapy for Auditory Hallucinations
This is a randomized controlled trial, examining the effects of a computerized, internet-based Cognitive Behavioral Therapy (CBT) Intervention for persons with a schizophrenia spectrum disorder who experience distressing auditory…
- Trial name
- NCT02192593
- Testing
- Computer CBT
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boston University Charles River Campus
Alcohol Use Disorder
Effect of Adapted Physical Activity on Sleep Quality in People With Alcohol Use Disorder
This feasibility study aims to assess interest, recruitment, and adherence to a supervised physical activity (APA) program among individuals with Alcohol Use Disorder (AUD).
- Trial name
- APhysOH (NCT06706349)
- Testing
- APA managed by qualified instructor, Autonomous APA
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Caregiver Burden, Alzheimer Disease
Reducing Burden in Care Partners of Community-Dwelling Persons With Dementia and Oropharyngeal Dysphagia
The goal of this clinical trial is to learn if a newly-created website tool, called WeCareToFeedDysphagia, helps to reduce feelings of burden in care partners of patients with Alzheimer's disease and related dementias (AD/ADRD)…
- Conditions
- Caregiver Burden, Alzheimer Disease, Dementia, Oropharyngeal Dysphagia
- Trial name
- NCT06557863
- Testing
- WeCareToFeedDysphagia web tool
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- Northwell Health
Primary Insomnia
Brisk Walking Training Compared with Cognitive Behavioral Therapy for the Treatment of Chronic Primary Insomnia in People Aged 60 Years or Above: a Randomized, Partially Blinded, Non-inferiority Trial
This study is a single-blinded (outcome assessor) and parallel-group non-inferiority RCT. Chinese older adults aged ≥60 years with chronic primary insomnia will be randomized evenly (1:1) to either the brisk walking training…
- Trial name
- NCT06850272
- Testing
- Brisk walking, Cognitive-behavioral therapy for insomnia
- Where
- Hong Kong
- Volunteers
- 92 people
- Sponsor
- Chinese University of Hong Kong
Sleep Disturbances
Effects of Brainwave Audio on Sleep in People With Sleep Disturbances
This exploratory study examines changes in sleep patterns during a four-week auditory stimulation intervention in 30 adults with self-reported sleep difficulties.
- Trial name
- NCT07909187
- Testing
- Brainwave Audio
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- Kaohsiung Armed Forces General Hospital
Insomnia, HIV
A Pragmatic Pilot Study of Cognitive Behavioural Therapy for Insomnia Among People Living With HIV
Insomnia is a problem for approximately 75% of people living with HIV, which is much higher than the 6% to 10% of people with insomnia in the general population.
- Trial name
- NCT02887209
- Testing
- CBT-I
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Toronto Metropolitan University
Alzheimer Disease, Dementia
Care Coordination System for People With Dementia
Dementia, a chronic disease of aging, is characterized by progressive cognitive decline that interferes with independent functioning.
- Conditions
- Alzheimer Disease, Dementia, Dementia Alzheimers
- Trial name
- NCT04308512
- Testing
- Active Nili device, Passive Nili system
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Bijan Najafi, PhD
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