Clinical trials: Persons With Psychiatric Disorders
Anxiety Disorders, OCD
Digital Coach to Support Exposure Therapy Homework for Anxious Youth
This study is testing a digital tool called BraveBot for young people who are receiving cognitive behavioral therapy (CBT) for anxiety, OCD, or related problems. BraveBot is a computer program, not a person.
- Trial name
- NCT07666672
- Testing
- BraveBot, Self-Guided Exposure Therapy Homework
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- Massachusetts General Hospital
Alzheimer Disease
Playful Multimodal Intervention, Monitoring and Decision Support for Activation of People With Alzheimer's Dementia
The worldwide prevalence of dementia is increasing. Pharmaceutical therapies, at the best, slow the degenerative process, observable in Alzheimer's disease (AD).
- Trial name
- M-AAL (NCT04628702)
- Testing
- tablet training
- Where
- Austria
- Volunteers
- 24 people
- Sponsor
- Medical University of Graz
Mental Health Impairment, Peer Group
Paths to Everyday Life (PEER) - a Community-based Peer Support Intervention
The aim of this randomized, two-arm, investigator initiated, multi municipal, parallel-group superiority trial is to compare the effect on self-reported personal recovery of the following interventions: (1) 10-week group-based…
- Conditions
- Mental Health Impairment, Peer Group, Mental Health Disorder, Problems Psychosocial
- Trial name
- PEER (NCT04639167)
- Testing
- Paths to everyday life (PEER)
- Where
- Denmark
- Volunteers
- 299 people, healthy volunteers welcome
- Sponsor
- Amager Hospital
HIV, Stigma, Social
Using the Ending Self-Stigma Intervention to Reduce Internalized Stigma Among People Living With HIV Who Use Substances
The goal of this clinical trial is to test an intervention to reduce stigma among people living with HIV who use opioids and cocaine.
- Conditions
- HIV, Stigma, Social, Substance Use
- Trial name
- IRIS (NCT05704764)
- Testing
- Ending Self Stigma for Persons living with HIV and Use Substances
- Where
- 2 sites in United States
- Volunteers
- 70 people
- Sponsor
- Friends Research Institute, Inc.
Neuromuscular Diseases, Neurodevelopmental Disorders
Nebulised Hypertonic Saline to Decrease Respiratory Exacerbations in Neuromuscular Disease or Neurodisability
Research Aim: This study investigates whether a 12-month treatment with hypertonic saline (salty water) can reduce antibiotic use in individuals with neuromuscular disease or cerebral palsy who frequently experience chest…
- Conditions
- Neuromuscular Diseases, Neurodevelopmental Disorders, Cerebral Palsy
- Trial name
- SPICE-UP (NCT06134401)
- Testing
- saline
- Where
- 2 sites in United Kingdom
- Volunteers
- 40 people
- Sponsor
- Imperial College London
Schizophrenia
An Extension Study to a Clinical Study That Will Continue to Evaluate the Effectiveness and Safety of SEP-363856 in People With Schizophrenia That Switch to SEP-363856 From Their From Their Current Antipsychotic Medication
An Extension study to a clinical study that will continue to evaluate the effectiveness and safety of SEP-363856 in people with schizophrenia that switch to SEP-363856 from their current antipsychotic medication.
- Trial name
- NCT05741528
- Testing
- SEP-363856
- Where
- 16 sites in United States
- Volunteers
- 75 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Mental Illness
The Effectiveness of a Recovery Program for People With Mental Illness.
Recovery-oriented approach has been the main trend in mental health field. However, few recovery-oriented programs are available in Taiwan, and many Taiwanese people with mental illness don't understand the concepts of recovery.
- Trial name
- NCT04400565
- Testing
- Recovery group
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- National Cheng-Kung University Hospital
Opioid Use Disorder
Supporting Treatment for Opioids and Recovery Capital (STORC) - R61 Phase
We are studying whether training an identified support person and providing patient navigation (i.e. a peer recovery specialist assisting you with finding the right support) after delivery can increase "recovery capital"-the…
- Trial name
- STORC R61 (NCT07787039)
- Testing
- STORC
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Friends Research Institute, Inc.
Depressive Disorder
A Multi-component Intervention to Improve Medication Adherence in People With Depressive Disorders
Objective: The study of medication adherence in depression (MAPDep study) aims to evaluate the effectiveness and cost-effectiveness of a multi-component strategy to enhance patient-centered care to improve adherence toward…
- Trial name
- MAPDep (NCT03668457)
- Testing
- Intervention to Patients, Intervention to Psychiatrists, Control
- Where
- Spain
- Volunteers
- 170 people
- Sponsor
- Servicio Canario de Salud
Cognition Disorder, Alzheimer Disease
REPAIR Sleep Study
The goal of this study is to learn whether a videoconference-delivered CBT-I program (REPAIR Sleep) can improve sleep and psychological well-being in caregiver-PLwD dyads.
- Trial name
- NCT07572565
- Testing
- REPAIR Sleep, Healthy Living
- Volunteers
- 120 people
- Sponsor
- Emory University
Depression, Anxiety
The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression and/or Generalized Anxiety Disorder
This study will measure the effects of MET-2 on symptoms of depression and anxiety using pre- and post-treatment scores for overall depression and anxiety and other symptoms of depression, such as sleep and anhedonia.
- Trial name
- NCT04052451
- Testing
- MET-2
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- NuBiyota
Technology
Anti-wandering System for People With Intellectual Disability
The study has 6 research questions regarding the use of the anti-wandering system in day activity centre cum hostel for persons with intellectual disabilities: Primary study questions: 1.
- Trial name
- NCT05785702
- Testing
- The anti-wandering system
- Where
- Hong Kong
- Volunteers
- 60 people
- Sponsor
- The University of Hong Kong
Adjustment Impairment, Accident
SelFIT: Internet-based Treatment for Adjustment Problems After an Accident
In this study, people who suffer from adjustment problems after having experienced an accident will be randomized to one of two study groups.
- Conditions
- Adjustment Impairment, Accident, Adjustment Disorders, Mental Disorder
- Trial name
- SelFIT (NCT03785912)
- Testing
- Internet-based self-help
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- University of Bern
Nicotine Addiction
Electronic Cigarettes as a Harm Reduction Strategy Among People Living With HIV/AIDS
This is a research study to understand and determine the effectiveness of electronic cigarettes versus nicotine replacement therapy in adults who smoke and also live with HIV/AIDS in effort to reduce cigarette smoking.
- Trial name
- NCT04218708
- Testing
- Nicotine patch and gum, Minnesota Nicotine Withdrawal Scale (MNWS), ASSIST (the Alcohol, Smoking and Substance Involvement Screening)
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- NYU Langone Health
Tobacco Use Disorder/Cigarette Smoking, HIV
Smoking Cessation Medication And Rewards Using a Teamlet to Treat Tobacco Use Disorder (SMARTTT 2.0) Among Persons With HIV: A Multi-site Hybrid Type 2 Effectiveness-implementation Trial
Cigarette smoking is an important cause of illness and death among persons with HIV (PWH). This project will study the impact of adding contingency management (use of financial rewards) to receiving medications and counseling on…
- Trial name
- NCT07835555
- Testing
- nicotine patch, nicotine gum, nicotine lozenge, varenicline, bupropion, Multi-target Contingency Management, Teamlet booster
- Where
- 5 sites in United States
- Volunteers
- 794 people
- Sponsor
- Yale University
Anxiety Disorders, Depression
Interned-delivered Intervention Based on Acceptance Principles
The main objectives for the online intervention were the following: Designing and implementing an internet-delivered prevention program based on acceptance principles, to support LGBT participants to tackle emotional difficulties…
- Conditions
- Anxiety Disorders, Depression, Mental Health Issue, Well-Being
- Trial name
- LGBT (NCT05514964)
- Testing
- Feasibility study
- Where
- Romania
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- West University of Timisoara
Dementia, Informal Caregivers (Family and Friends)
Dementia Choirs for Social and Psychological Wellbeing
Loneliness is common in both persons living with dementia and their informal caregivers, and a factor negatively affecting disease progression, health and wellbeing.
- Trial name
- NCT07011498
- Testing
- Dementia choir
- Where
- Norway
- Volunteers
- 100 people
- Sponsor
- Norwegian Academy of Music
Dementia, Mild
Eerder Erbij: The Path Towards Offering Timely Support for People With Dementia and Their Caregivers
INTRODUCTION AND RATIONALE It has been estimated that at least 50% of the home living persons with dementia in the Netherlands receive little or no formal care and support (Zorgstandaard Dementie, 2013).
- Trial name
- EE (NCT06455163)
- Testing
- Eerder Erbij
- Where
- Netherlands
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- VU University of Amsterdam
Depression - Major Depressive Disorder, Anxiety
Comparative Effects of Acceptance and Commitment Therapy, Cognitive Behavioral Therapy, and Treatment-as-Usual on Depression Among People With Marital Crisis
This parallel three-arm, single-blind (assessor-blinded), randomized controlled trial (RCT) aims to compare the effects of ACT, CBT, and treatment-as-usual (TAU) on the severity of depressive symptoms (primary outcome), the…
- Conditions
- Depression - Major Depressive Disorder, Anxiety, Marital Conflict
- Trial name
- NCT07808021
- Testing
- Acceptance and Commitment Therapy, Cognitive Behavioral Therapy
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Universiti Sains Malaysia
Anxiety
Individual and Family Therapy for Children With Anxiety Disorders
The purpose of this study is to compare three treatments to determine which is most effective in reducing anxiety in children.
- Trial name
- NCT00081406
- Testing
- Individual Child CBT, Family CBT, Education/Support/Attention
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Temple University
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