Clinical trials: Persons With Psychiatric Disorders
Dementia
BrainLive Connect: Non-professional Delivered CST for People Living With Dementia
The goal of this mixed method study is to evaluate whether the volunteer-led Cognitive Stimulation Therapy (CST) under the BrainLive Connect programme is effective for improving cognitive function and quality of life of people…
- Trial name
- NCT07531589
- Testing
- Cognitive Stimulation Therapy (CST), Usual Care
- Where
- Hong Kong
- Volunteers
- 520 people
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment, Alzheimer Disease
Understanding Circadian Responses to Light in Persons With Mild Cognitive Impairment
The purpose of this research study is to investigate the relationship between light, the thickness of the pigment at the back of your eye, melatonin levels, and memory.
- Trial name
- NCT05411822
- Testing
- Lighting Intervention Blue light, Lighting Intervention Green light, Dim-light control condition
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Schizoaffective Disorder
Mindfulness Meditation as a Rehabilitation Strategy for Persons With Schizophrenia
The purpose of this study is to develop a treatment manual for mindfulness meditation to be taught in a group format to individuals with schizophrenia who are engaged in vocational rehabilitation.
- Conditions
- Schizophrenia, Schizoaffective Disorder, Psychotic Disorders
- Trial name
- NCT00936351
- Testing
- Mindfulness Meditation, Support Group (control)
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- US Department of Veterans Affairs
HIV Infections, Frailty
Sleep Quality and Frailty Among People Living With HIV
With effective antiretroviral therapy (ART), people living with HIV (PLWH) are living longer and are increasingly experiencing aging-related conditions such as frailty and sleep problems.
- Conditions
- HIV Infections, Frailty, Sleep Quality, Oral Frailty
- Trial name
- NCT07880054
- Testing
- No intervention (observational assessments)
- Where
- Taiwan
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- National Sun Yat-sen University
Polypharmacy, Dementia
Shared Decision Making About Medication Use for People With Multiple Health Problems
The Shared Decision Making about Medication Use for People with Multiple Health Problems study will assess the feasibility and acceptability of a deprescribing educational intervention in primary care for patients with mild…
- Conditions
- Polypharmacy, Dementia, Multiple Chronic Conditions, Deprescribing
- Trial name
- NCT05156073
- Testing
- Educational Materials
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dementia
Multisensory Physical Exercises in People With Cognitive Impairment
The main objective of the study is to evaluate the efficacy of a combined training program of physical exercise and multisensory stimulation (Physiocognitive Integration) in people with mild/moderate cognitive impairment.
- Trial name
- NCT05295966
- Testing
- Cognitive therapy, Physiocognitive Integration
- Where
- Spain
- Volunteers
- 25 people
- Sponsor
- Universidad Rey Juan Carlos
Psychosis
Supported Employment in a Swedish Context
This project aims at generating evidence of a work-rehabilitation strategy that benefits the people with severe mental illness (SMI) who want to work, increase their sense of well-being and integration in society, decrease their…
- Trial name
- NCT00960024
- Testing
- Individual Placement and Support-vocational rehabilitation, Vocational rehabilitation available
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Vardalinstitutet The Swedish Institute for Health Sciences
Dementia
Reducing Agitation in People With Dementia: the Customized Activity Trial
Over 5 million Americans have Alzheimer's disease or a related dementia, a progressive and irreversible neurodegenerative condition, affecting also close to 15 million family caregivers (CG).
- Trial name
- TAP (NCT01892579)
- Testing
- Tailored Activity Program, Home Safety and Education Program
- Where
- United States
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Substance Related Disorder, Personality Disorders
The Impact of the Use of the MAURISSE Application in People Suffering From an Addiction.
Substance Use Disorders (SUD) are associated with cognitive schemas that lead to care attrition and mistrust towards care. Considering this, establishing a strong, trustful relationship between the patient and the healthcare team…
- Trial name
- ALMA (NCT05964296)
- Testing
- The MAURISSE application use, Usual care
- Where
- France
- Volunteers
- 60 people
- Sponsor
- University Hospital, Toulouse
HIV Infections, Schizophrenia
Effectiveness of the Screen, Test, Immunize, Reduce Risk, and Refer (STIRR) Intervention for People With Both a Mental and Substance Abuse Disorder
This study will determine the effectiveness of the STIRR (Screen, Test, Immunize, Reduce risk, and Refer) intervention in increasing rates of testing, immunization, referral, and treatment for blood-borne diseases, such as…
- Conditions
- HIV Infections, Schizophrenia, Schizoaffective Disorder, Bipolar Disorder
- Trial name
- NCT00316303
- Testing
- Twinrix, Enhanced treatment as usual
- Where
- United States
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Dartmouth-Hitchcock Medical Center
HIV-1-infection, Opioid Use Disorder
Evaluation of Switch to Dolutegravir/Lamivudine (DTG/3TC) From Current Suppressive Antiretroviral Therapy in People Living With HIV (PLWH) Receiving Opioid Agonist Therapy (OAT)
The goal of this clinical trial is to determine the efficacy of Dolutegravir/Lamivudine (DTG/3TC), or "Dovato", in virally-suppressed (HIV-1 RNA < 200 copies/mL) individuals receiving opioid agonist therapy such as methadone…
- Trial name
- NCT06580873
- Testing
- DOVATO
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Saskatchewan Health Authority - Regina Area
Gambling, Pathologic
Computer-based Self-Help Program for People With Gambling Problems
The study examines the effectiveness of a computer-based self-help-program for individuals with problematic or pathological gambling behavior.The main objective of the study is to investigate the extent to which the online…
- Trial name
- NCT03372226
- Testing
- Online self-help program
- Where
- Germany
- Volunteers
- 155 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Dementia
NightCAP: Reducing Hypnotic Drug Use and Improving Night-time Care
Dementia is a devastating condition characterised by progressive loss of cognition leading to loss of independence and eventually death.
- Trial name
- NightCAP (NCT04373668)
- Testing
- Hypnotic Medication Review, Structured Sleep Hygiene, Night Time Care Activities Programme
- Where
- United Kingdom
- Volunteers
- 720 people
- Sponsor
- University of Exeter
Schizophrenia
Exercise Intervention for People With Schizophrenia (CREW)
The study aims to investigate the feasibility and adherence of long-term, moderate-intensity different types of physical activity programs for individuals with schizophrenia.
- Trial name
- CREW (NCT06044038)
- Testing
- Physical activity, Cognitive rehabilitation program
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Università degli Studi di Ferrara
Alzheimer Disease (AD), Occupational Therapy
Understanding the Lived Experience and Bereavement of Caregivers of People With Alzheimer's Disease
The main objective of this study is to explore the lived experience of caregivers and family members of people with Alzheimer's disease (AD), from the beginning of caregiving through the bereavement process following the…
- Conditions
- Alzheimer Disease (AD), Occupational Therapy, Family Caregivers
- Trial name
- ALCARE (NCT07251738)
- Testing
- Assessment of occupational balance, role performance, caregiving burden, and quality of life among carers or family members of individuals with Alzheimer's disease (AD).
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
Psychiatric or Mood Diseases or Conditions, Neuropsychiatric Syndrome
Effect and Cost-effectiveness of the Everyday Life Rehabilitation Intervention
The person-centered, motivational, recovery-, and activity-based intervention model 'Everyday Life Rehabilitation´ (ELR), integrated in sheltered and supported housing facilities for people with severe psychiatric disabilities…
- Conditions
- Psychiatric or Mood Diseases or Conditions, Neuropsychiatric Syndrome, Psychosis, Autism
- Trial name
- ELR (NCT05056415)
- Testing
- Everyday Life Rehabilitation (ELR), Treatment as usual (TAU)
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Umeå University
Schizophrenia
Feasibility of Providing Cognitive Remediation to People With Schizophrenia in a Clinical Network
This study will test whether a cognitive remediation program to treat people with schizophrenia can be successfully implemented in a network of research clinics.
- Trial name
- NCT00930150
- Testing
- Targeted cognitive training, Computer control, Bridging groups
- Where
- 9 sites in United States
- Volunteers
- 52 people
- Sponsor
- National Institute of Mental Health (NIMH)
Spinal Cord Injuries, Anxiety
Internet-delivered Cognitive Behavioural Therapy for Persons With Spinal Cord Injury
In Canada the prevalence of spinal cord injury (SCI) is approximately 85,556, with incidence rates of traumatic and non-traumatic SCI at 1,785 and 2,286 cases per year, respectively.
- Conditions
- Spinal Cord Injuries, Anxiety, Depression
- Trial name
- NCT03963843
- Testing
- Guided ICBT, SCI rehabilitation mental health education
- Where
- 2 sites in Canada
- Volunteers
- 122 people
- Sponsor
- University of Regina
Myasthenia Gravis
Cognitive Functioning in People With Myasthenia Graivs: Impact on Daily Life Activities, Work, Disability and Quality of Life
MYCOG primarily aims to estimate the prevalence of cognitive difficulties in patients with MG treated at Besta Institute. Secondary aims include: a) assess the degree to which cognitive difficulties are associated to work…
- Trial name
- MYCOG (NCT06718855)
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Intellectual Disabilities, Developmental Disability
Health Engagement & Access Through Learning, Training, and Health-coaching With People With Intellectual and/or Developmental Disabilities
The purpose of this study is to see if a combination of an educational curriculum and health coaching embedded within Special Olympics improves health outcomes and healthcare access compared to regular Special Olympics sport and…
- Trial name
- HEALTH 4 ME (NCT07475117)
- Testing
- Comprehensive Community Health, Regular Special Olympics programming
- Where
- United States
- Volunteers
- 1,040 people
- Sponsor
- University of Wisconsin, Madison
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