Clinical trials: Persons With Psychiatric Disorders
Dementia
Caregiver Bootcamp
This study will assess the preliminary efficacy of a synchronous/asynchronous psychoeducation program designed to promote caregiving mastery in the immediate time period after a dementia diagnosis.
- Trial name
- NCT07006116
- Testing
- Synchronous/asynchronous online course
- Where
- United States
- Volunteers
- 64 people
- Sponsor
- Emory University
Major Depression, Bipolar Disorder
Longitudinal Study of People Presenting for First Treatment of a Mood Disorder
The goal of this project is to study the course and outcome of illness in individuals who present with a first episode of depression or mania, or who have a recurrent disorder but have never received treatment.
- Trial name
- NCT01529905
- Where
- Canada
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Opioid Use Disorder
A Study to Test Whether BI 1356225 Improves Impulsive Behavior in People With Opioid Use Disorder Who Are Taking Buprenorphine
This study is open to people between 18 and 65 years of age with opioid use disorder. Opioid use disorder is also called opioid addiction or opioid dependence.
- Trial name
- NCT06628622
- Testing
- BI 1356225
- Where
- 5 sites in United States
- Volunteers
- 12 people
- Sponsor
- Boehringer Ingelheim
Psychosis
Strategic Timing of Resistance Training to Guard Against Antipsychotic-Induced Metabolic Syndrome
This study is evaluating whether a supervised resistance training (strength training) programme is feasible to perform in a first-episode psychosis service.
- Trial name
- START GAAIMS (NCT07386483)
- Testing
- Resistance training programme
- Where
- Ireland
- Volunteers
- 40 people
- Sponsor
- University College Dublin
Subthreshold Depression, Exercise
The Effect of Exercise on Cognition and Preventing Depression in Young People
It is estimated that approximately 30% of child and adolescents manifest subthreshold depression (including other specified depressive disorder and unspecified depressive disorder), which can further develop into major depression…
- Conditions
- Subthreshold Depression, Exercise, Clinically-well, Cognitive Change
- Trial name
- NCT04816617
- Testing
- Aerobic exercise intervention, Psycho-education
- Where
- China
- Volunteers
- 628 people, healthy volunteers welcome
- Sponsor
- Guangzhou Psychiatric Hospital
Autism Spectrum Disorder
Development and Validation of a System for the Anticipation of Challenging Behaviors
Most people with autism spectrum disorder (ASD) present at least one form of challenging behavior (CB). Self-injurious, aggressive, and disruptive CBs linked with social interaction, community-based service exclusion, and a life…
- Trial name
- NCT05340608
- Testing
- Smart, non-invasive shirt - Physiological parameters, Smart, non-invasive shirt - Relation with challenging behaviors, Smart, non-invasive shirt - Proof of Concept
- Where
- Israel
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Ariel University
Dementia
Deprescribing Potentially Inappropriate Medications in the Emergency Department for Persons Living With Dementia
Aim 1: To demonstrate the feasibility by determining proportion of completed medication reconciliation, Central Nervous System active Potentially Inappropriate Medication (CNS PIM) use among patients with Alzheimer's Disease and…
- Trial name
- IMPACT (NCT06273917)
- Testing
- PRIDE
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Institute on Aging (NIA)
Mild Cognitive Impairment
Measuring the Impact of Cognitive and Psychosocial Interventions in Persons With Mild Cognitive Impairment
Memory interventions are training programs that provide a variety of cognitive and psychological strategies meant to improve memory.
- Trial name
- NCT01448148
- Testing
- Cognitive intervention, Psychosocial intervention
- Where
- 2 sites in Canada
- Volunteers
- 145 people
- Sponsor
- Centre de Recherche de l'Institut Universitaire de Geriatrie de Montreal
Alcohol Use Disorder, Insomnia
Daridorexant for People With Insomnia and Alcohol Use Disorder Study
The goal of this clinical trial is to see if a sleep medication, daridorexant (DTX), can help decrease drinking in people who have alcohol use disorder (AUD) and insomnia.
- Trial name
- DIAS (NCT07701928)
- Testing
- Daridorexant, Brief Counseling, MEMS and Medication Accounting
- Where
- United States
- Volunteers
- 205 people
- Sponsor
- Sterling McPherson
Anorexia Nervosa
Motivation to Exercise in People With Anorexia Nervosa
The purpose of this research study is to determine the importance and level of physical activity in people with Anorexia Nervosa.
- Trial name
- NCT00961428
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- New York State Psychiatric Institute
Alzheimer Dementia, Alzheimer's Disease
Association of Cognition With Functional Mobility in People With Alzheimer's Disease
This study aimed to investigate relationship between cognitive function and functional mobility in Alzheimer's disease.
- Conditions
- Alzheimer Dementia, Alzheimer's Disease, Dementia, Alzheimer Type
- Trial name
- NCT05113732
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Istanbul University - Cerrahpasa
ADHD
Benefits of ADHD Treatment in Detained People
Attention deficit hyperactivity disorder (ADHD) is characterized by difficulties paying attention, poor impulse control, and hyperactive behaviors.
- Trial name
- BATIR (NCT05842330)
- Testing
- Concerta
- Where
- Switzerland
- Volunteers
- 150 people
- Sponsor
- Stéphanie Baggio
Depressive Disorder, Major
A Study to Test Different Doses of BI 1569912 in People With Depression
This study is open to adults between 18 and 65 years of age with a type of depression called major depressive disorder. The purpose of the study is to find out whether a medicine called BI 1569912 helps people with depression.
- Trial name
- NCT06558344
- Testing
- 5 mg BI 1569912, 10 mg BI 1569912, 20 mg of BI 1569912
- Where
- 41 sites in United States, Japan
- Volunteers
- 225 people
- Sponsor
- Boehringer Ingelheim
Schizophrenia, Bipolar Disorder
Development of a Mobile Heath Augmented Brief Suicide Prevention Intervention for People With SMI
Schizophrenia and bipolar disorder are associated with high risk for suicide, yet there are few brief interventions that directly target suicide prevention in this large population.
- Conditions
- Schizophrenia, Bipolar Disorder, Suicide and Self-harm
- Trial name
- NCT03198364
- Testing
- Safety and Recovery Therapy, Mobile Augmentation
- Where
- United States
- Volunteers
- 78 people
- Sponsor
- University of California, San Diego
Affective Disorder
Effectiveness of a Cognitive Remediation Intervention Based on Virtual Reality for Promotion of Cognitive Functioning and Participation in Daily Life Among Persons With Affective Disorder
The purpose of this study is to test the efficacy of remedial cognitive intervention using The Functional Brain Trainer VR (FBT, Intendo ©) to improve cognitive functioning, participation in daily life occupations, and functional…
- Trial name
- NCT04288609
- Testing
- Intendu, Paper and Pencil cognitive remediation training
- Volunteers
- 40 people
- Sponsor
- Geha Mental Health Center
Alzheimer Disease, Dementia
Processing of Music in Alzheimer Patients
Correlation of musicality, brain atrophy in brain areas relevant for music processing and the stage of Alzheimer´s disease.
- Conditions
- Alzheimer Disease, Dementia, Amusia
- Trial name
- MUKU-DEM (NCT04132193)
- Volunteers
- 50 people
- Sponsor
- Turku University Hospital
Alzheimer's Disease
A Clinical Trial to Learn About the Effects of VHB937 in People With Early Alzheimer's Disease
This is a multicentre, randomized, double-blind, placebo-controlled, parallel group Phase II study to evaluate the efficacy and safety of VHB937 in participants with early AD followed by an Extension.
- Trial name
- NCT07094516
- Testing
- VHB937
- Where
- 73 sites in United States, Australia and 13 more
- Volunteers
- 97 people
- Sponsor
- Novartis Pharmaceuticals
Dementia Alzheimers, Alzheimer Disease
Person-Environment Fit for Persons With Dementia
This trial will assess feasibility of a non-pharmacological intervention for persons living with Alzheimer's disease and related dementias (ADRD) to improve behavioral and psychiatric symptoms of dementia and functional…
- Trial name
- NCT05722743
- Testing
- Harmony at HOME, National Institute on Aging Program
- Where
- United States
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Elizabeth K Rhodus
Caregiver Subjective Burden, Depressive Symptoms
Effectiveness of an Online Training and Support Program (iSupport) for Informal Dementia Caregivers
Informal caregivers of people with dementia are at greater risk of developing physical and mental health problems when compared to the general population and to informal caregivers of people with other chronic diseases.
- Conditions
- Caregiver Subjective Burden, Depressive Symptoms, Anxiety Symptoms
- Trial name
- iSupportPT (NCT04104568)
- Testing
- iSupport for dementia - European-Portuguese version, e-book (comparator)
- Where
- Portugal
- Volunteers
- 184 people
- Sponsor
- Universidade do Porto
Alcoholism, Alcohol Dependence
Alcoholism Assessment and Treatment
The purpose of this study is to gather information about people s drinking histories and to evaluate them for other research studies being conducted at the National Institute on Alcohol Abuse and Alcoholism (NIAAA).
- Conditions
- Alcoholism, Alcohol Dependence, Alcohol Drinking Related Problems
- Trial name
- NCT00106093
- Where
- United States
- Volunteers
- 1,192 people
- Sponsor
- National Institute on Alcohol Abuse and Alcoholism (NIAAA)
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