Clinical trials: Persons With Psychiatric Disorders
Obesity, Dietary Inflammatory Index (DII)
Dietary Inflammatory Potential in Young Pleople With Obesity
The increase in adipose tissue in the young population is one of the most important and worrying public health problems because it persists in adulthood, constituting a risk factor for chronic degenerative diseases with social…
- Trial name
- DIP (NCT06971666)
- Volunteers
- 170 people
- Sponsor
- Instituto Tecnológico y de Estudios Superiores de Occidente
Dementia, Dementia, Vascular
Palliative Care for Persons With Late-stage Alzheimer's and Related Dementias and Their Caregivers
Millions of Americans have late-stage Alzheimer's and related dementias (ADRD), causing suffering due to loss of awareness of self and family, progressive dependency, physical and neuropsychiatric symptoms, and physical…
- Conditions
- Dementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia Frontal
- Trial name
- ADRD-PC (NCT04948866)
- Testing
- ADRD-PC Program
- Where
- 5 sites in United States
- Volunteers
- 884 people
- Sponsor
- University of North Carolina, Chapel Hill
PTSD
Virtual Reality Prolonged Exposure (PE) for Bus Bomb Survivors
This study will examine whether the use of a Virtual World will be effective in helping treat Posttraumatic Stress Disorder (PTSD). This is a pilot study, with five victims of bus bombings who have developed PTSD.
- Trial name
- NCT00474305
- Testing
- Virtual Reality Treatment for PTSD
- Where
- Israel
- Volunteers
- 5 people
- Sponsor
- Hadassah Medical Organization
Chronic Pain, Chiari Malformation
Online Acceptance and Commitment Therapy for Chronic Pain in Sample of People With Chiari Malformation
Twenty percent of US adults report chronic pain symptoms. Both psychological symptoms and sleep issues commonly co-occur with chronic pain.
- Trial name
- NCT04089670
- Testing
- Online Acceptance and Commitment Therapy Intervention
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- Kent State University
Narcolepsy
A Patient-Centric, Prospective, Observational, Non-Interventional Switch Study of XYWAV in Narcolepsy
The rationale for the patient-centric, prospective, observational, non-interventional study design of JZP258-402 is to evaluate the transition experience of participants with narcolepsy treated with oxybate and to examine the…
- Trial name
- NCT04803786
- Testing
- Transition from Xyrem to Xywav
- Where
- United States
- Volunteers
- 110 people
- Sponsor
- Jazz Pharmaceuticals
Cognition Disorders, Multiple Sclerosis
A Study of C105 on Cognitive Dysfunction in Persons With Multiple Sclerosis
The purpose of this study is to determine the safety and efficacy of C105 in treating the cognitive deficits that can occur due to multiple sclerosis.
- Trial name
- NCT00529581
- Testing
- C105
- Where
- 30 sites in United States
- Volunteers
- 150 people
- Sponsor
- Cognition Pharmaceuticals, LLC
Sleep Disturbance, Stress
Yoga for Persons With Severe Visual Impairment
This study aims to provide novel information on the feasibility of yoga interventions for secondary symptoms related to severe vision loss, such as sleep disturbances, negative mood states, fall risk and balance.
- Conditions
- Sleep Disturbance, Stress, Anxiety, Depression
- Trial name
- RPY (NCT01366677)
- Testing
- Yoga Intervention
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Borderline Personality Disorder
Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder
This study will determine whether dialectical behavior therapy and fluoxetine are more effective combined or alone in treating people with borderline personality disorder.
- Trial name
- NCT00533117
- Testing
- Fluoxetine, Dialectical Behavior Therapy, Supportive psychotherapy
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- New York State Psychiatric Institute
Multiple Sclerosis, Primary Progressive, Cognitive Impairment
Improving Cognition in People With Progressive Multiple Sclerosis Using Aerobic Exercise and Cognitive Rehabilitation
Given that up to 70% of people with secondary progressive MS are cognitively impaired, the search for effective treatments is considered a priority by people living with the disease.
- Trial name
- NCT03679468
- Testing
- Cognitive Rehabilitation, Aerobic Exercise
- Where
- Canada
- Volunteers
- 309 people
- Sponsor
- Sunnybrook Health Sciences Centre
Multiple Sclerosis, Gait Disorders, Neurologic
Investigating the Effects of Wearable Robotic Exoskeleton for Improving Mobility and Cognition in Persons With MS
The purpose of this research study is to evaluate the usefulness of a wearable robotic exoskeleton device (Ekso-GT), to improve learning and memory, and gait therapy in persons with walking disability due to Multiple Sclerosis.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Motility Disorder, Cognitive Impairment
- Trial name
- NCT04855825
- Testing
- Robotic Exoskeleton Rehabilitation, Conventional Gait Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Kessler Foundation
Emotional Disorder, Post COVID-19 Condition
Efficacy of the Unified Protocol for Transdiagnostic Treatment of Emotional Disorders (UP) in People With Post Covid-19 Condition.
The present multiple baseline single case trial will study the efficacy and acceptability of the "Unified Protocol for the Transdiagnostic Treatment of Emotional Disorders" in the treatment of emotional symptomatology and/or…
- Conditions
- Emotional Disorder, Post COVID-19 Condition, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT05581277
- Testing
- Unified Protocol for Transdiagnostic Treatment of Emotional Disorders
- Where
- 2 sites in Spain
- Volunteers
- 60 people
- Sponsor
- Instituto de Investigación Sanitaria Aragón
Alzheimer's Disease, Mild Cognitive Impairment
Investigating the Impact of Duration and Amount of Light on the Circadian System Response - Aim 3
Investigate the long-term impact of amount and duration of Tailored Lighting Intervention (TLI) obtained from Aims 1 and 2 on sleep, cognition, circadian marker, mood, and behavior in AD/ADRD patients.
- Trial name
- NCT06595030
- Testing
- Active Lighting Intervention, Control Lighting Intervention
- Where
- 2 sites in United States
- Volunteers
- 101 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Dementia
Yoga for Caregivers and Persons With Dementia
The purpose of this research is to determine the feasibility and acceptability of yoga classes for persons living with dementia (PLWD) and their care partners.
- Trial name
- YCPD (NCT05103839)
- Testing
- Gentle Yoga
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- Wake Forest University Health Sciences
Mental Disorders, Social Participation
Co-Creation Workshops With MaKey MaKey to Promote Participation Among People With Mental Health Conditions
This pilot study aims to design, implement, and conduct an initial evaluation of a group-based co-creation workshop program using MaKey MaKey and Scratch for adults attending a mental health day hospital.
- Conditions
- Mental Disorders, Social Participation, Empowerment, Motivation
- Trial name
- MaKey4All (NCT07704619)
- Testing
- MaKey MaKey and Scratch Co-Creation Workshop Program
- Volunteers
- 20 people
- Sponsor
- Universidade da Coruña
Panic Disorder, Generalized Anxiety Disorder
Collabri Flex - Effect of Collaborative Care for People With Anxiety Disorders in General Practice
The aim of the study Collabri Flex is to: Develop a Danish model for collaborative care for patients with anxiety in general practice, based on past experience gained in the Collabri Project.
- Conditions
- Panic Disorder, Generalized Anxiety Disorder, Social Phobia, Obsessive-Compulsive Disorder
- Trial name
- NCT03113175
- Testing
- Collaborative care, Consultations-Liaison
- Where
- Denmark
- Volunteers
- 302 people
- Sponsor
- Amager Hospital
Dementia, Caregiver Burden
MIND: Care Coordination for Community-living Person With Dementia
This is a 24-month, prospective, single- blind, randomized controlled trial evaluating the MIND at Home-streamlined dementia care coordination intervention (called MIND-S) in a cohort of 300 community-living persons with dementia…
- Trial name
- MIND at Home (NCT02396082)
- Testing
- MIND-S Intervention, Augmented Usual Care
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Parkinson Disease
Feasibility of a Behavioural Activation Protocol to Support People With Parkinson's Enhanced by VR
The proposed research project will involve developing and testing the feasibility of a 6 week Behavioural Activation (BA) programme for people with Parkinson's Disease, which will be enhanced by Virtual Reality exercise…
- Trial name
- BAPP-VR (NCT07038603)
- Testing
- BAPP-VR
- Where
- United Kingdom
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Queen's University, Belfast
Pain, Chronic, Mental Disorder
Evaluation of a Collaborative Intervention to Promote Employer Contact and RTW Among People With CMD or Chronic Pain
The overall aim of this cluster ranomized controlled trial is to investigate whether an intervention for collaboration between patient with CMD or chronic pain and employer (the Demand and Ability Protocol) can contribute to…
- Trial name
- NCT05216861
- Testing
- Demand and ability protocol, Collaborative interventions as usual
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Uppsala University
Cognitive Impairment, Dementia
Home Alone: An Intervention for People With Cognitive Impairment Who Live Alone
The goal of this clinical trial is to evaluate a program for adults who live alone and have some cognitive impairment (CI) to see if it is useful and acceptable.
- Conditions
- Cognitive Impairment, Dementia, Memory Loss
- Trial name
- NCT05746390
- Testing
- Home Alone
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Minnesota
Alzheimer Disease, Dementia
Jigsawdio Multisensory Platform for People With Mild Cognitive Impairment, Alzheimer's Disease, or Related Dementias
This study will evaluate Jigsawdio, a personalized multisensory jigsaw puzzle platform, for adults aged 60 years and older with mild cognitive impairment or mild dementia.
- Conditions
- Alzheimer Disease, Dementia, Mild Cognitive Impairment
- Trial name
- NCT07839286
- Testing
- Jigsawdio Multisensory Puzzle Platform, Standard Jigsaw Puzzle Activity
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Callahan-Young LLC DBA Jigsawdio
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