Clinical trials: Persons With Psychiatric Disorders
Sleep Disturbances, Depression
Methodology Issues in a Tailored Light Treatment for Persons With Dementia
Tailored light treatment will increase sleep efficiency, reduce depression and reduce agitation scores in those with Alzheimer's disease and related dementia
- Trial name
- NCT01816152
- Testing
- High Active intervention, Inactive intervention, Mid Level Active Intervention
- Where
- 2 sites in United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Schizoaffective Disorder
The Effectiveness of FMPO in Improving the Quality of Care for Persons With Severe Mental Illness.
The purpose of this study is to learn how to help veterans play a stronger role in shaping their mental health care. Specifically we want to see if we can help veterans improve their mental health treatment by helping them decide…
- Conditions
- Schizophrenia, Schizoaffective Disorder, Major Depression
- Trial name
- NCT00466323
- Testing
- Family Member Provider Outreach, Enhanced treatment as usual (e-TAU)
- Where
- 2 sites in United States
- Volunteers
- 238 people
- Sponsor
- US Department of Veterans Affairs
Depressive Disorder, Major
A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression
This is a home-based study in adults with depression. People who have been diagnosed with Major Depressive Disorder can participate in the study.
- Trial name
- NCT04423757
- Testing
- BI 1358894
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Boehringer Ingelheim
Schizophrenia, Schizoaffective Disorder
Oxytocin and CBSST for People With Schizophrenia
A significant proportion of people with schizophrenia are characterized by impaired ability to socially engage with others, which may reflect social aversion secondary to defeatist beliefs; decreased motivation for social…
- Trial name
- NCT01752712
- Testing
- CBSST + Oxytocin
- Where
- 2 sites in United States
- Volunteers
- 83 people
- Sponsor
- University of Maryland, Baltimore
Alzheimer Disease, Mild Cognitive Impairment
SUPPORT-D Intervention for Persons With Alzheimer's Disease and Their Caregivers
The purpose of this research is pilot test a nurse led intervention previously used in patients with pulmonary fibrosis and their caregivers in a new population (persons living with Mild Cognitive Impairment or Alzheimer's…
- Trial name
- NCT05501119
- Testing
- A Program of SUPPORT-D (dementia)
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Medical University of South Carolina
Mental Disorders
Efficacy of the Recovery Workbook as a Psychoeducational Tool for Facilitating Recovery
The present study will determine if Spaniol and colleague's (1994) Recovery Workbook group intervention is an effective clinical tool to move a person with SMI along in their journey of recovery.
- Trial name
- NCT00375167
- Testing
- Recovery Workbook Training (psychoeducational training), ACT as usual
- Where
- Canada
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Queen's University
Cardiovascular Risk Factors, Serious Mental Illness
Intervention Trial to Decrease Cardiovascular Risk in Persons With Serious Mental Illness
This study will determine whether a program where a health coach works with participants on heart healthy behaviors and treatment of risk factors is coordinated with primary care can reduce overall heart disease risk in people…
- Trial name
- IDEAL (NCT02127671)
- Testing
- IDEAL intervention, Control
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Johns Hopkins University
Schizophrenia
The Effects of Cannabis Use in People With Schizophrenia on Clinical, Neuropsychological and Physiological Phenotypes
Approximately 25% of people with schizophrenia abuse marijuana. These people may be using marijuana to self-medicate symptoms such as hallucinations (hearing or seeing things that are not heard or seen by others) or delusions…
- Trial name
- NCT01832766
- Testing
- Dronabinol
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Colorado, Denver
Depressive Disorder, Major
A Study to Test How Well Different Doses of BI 1569912 Are Tolerated and How Well They Work in People With Depression Who Take Anti-depressive Medication
This study is open to adults between 18 and 65 years of age who have depression (major depressive disorder). People with a current depressive episode lasting between 2 months and one and a half years can join the study.
- Trial name
- NCT04937829
- Testing
- 5 mg BI 1569912, 20 mg BI 1569912
- Where
- 10 sites in United States
- Volunteers
- 59 people
- Sponsor
- Boehringer Ingelheim
Alzheimer Disease, Dementia
SAFE at Home: A Service to Provide Social Engagement to Community-Dwelling Persons With Dementia
The proposed Phase 1 study will involve initial development and evaluation of a new service called Social Activities For Engagement at Home or SAFE at Home (SaH).
- Conditions
- Alzheimer Disease, Dementia, Dementia, Vascular, Dementia, Mixed
- Trial name
- NCT05516147
- Testing
- SAFE at Home
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Hopeful Aging
Aging, Cognitive Function Abnormal
Executive Functioning Training Study
Cognitive aging in people with HIV (PWH) is of increasing concern for several reasons: 1) between 52%-59% of PWH experience cognitive impairment known as HIV-Associated Neurocognitive Disorder (HAND) which impacts everyday…
- Conditions
- Aging, Cognitive Function Abnormal, Cognitive Performance, Cognitive Training
- Trial name
- EFT (NCT05598047)
- Testing
- Executive Functioning Training
- Volunteers
- 119 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Schizophrenia
Improving Medication Adherence Among People With Schizophrenia Through the Use of 2-way Pagers
This study will determine whether using a pager improves medication adherence in people with schizophrenia.
- Trial name
- NCT00392236
- Testing
- 2-way pager, Treatment as usual
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Northwell Health
Dementia, Alzheimer Disease
Digital Interventions in Neuro-Rehabilitation: Gotcha!
Aims and background Everyone forgets the names of people they should know at times. Having dementia makes this problem worse. People with dementia have told expressed they forget the names of people they care about and this can…
- Conditions
- Dementia, Alzheimer Disease, Anomia
- Trial name
- NCT04570215
- Testing
- Gotcha! Therapy application, Gotcha Therapy application: Maintenance
- Where
- United Kingdom
- Volunteers
- 48 people
- Sponsor
- University College, London
Alzheimers Disease
A Research Study Looking at the Effect of Semaglutide on the Immune System and Other Biological Processes in People With Alzheimer's Disease
The study is being conducted to understand how the medicine, semaglutide, affects the immune system and other biological processes in people with Alzheimer's disease.
- Trial name
- NCT05891496
- Testing
- Semaglutide
- Where
- 12 sites in United States, Canada and 4 more
- Volunteers
- 23 people
- Sponsor
- Novo Nordisk A/S
Physical Disability, Chronic Mental Disorder
Persons With Disabilities Generating Quality Metrics
No standard way exists to measure the quality of medical care or independent living long-term services and supports provided to persons with disabilities.
- Trial name
- NCT02390557
- Testing
- Survey, YESHealth
- Volunteers
- 451 people
- Sponsor
- Massachusetts General Hospital
Hepatitis C, Chronic, Substance Use Disorders
Linkage to Care for Persons With Hep C Infection
Hepatitis C Virus (HCV) infection is an ongoing challenge in the United States, with an estimated 2.4 million individuals living with HCV in 2016.
- Trial name
- NCT05397067
- Testing
- Peer specialist (PS), Incentives, telehealth visits
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Carilion Clinic
Alzheimer Disease
A Study of V950 in People With Alzheimer Disease (V950-001 AM7)
The purpose of this study is to test the safety, tolerability and the immune response to an investigational vaccine, V950, with or without ISCOMATRIX™ (IMX).
- Trial name
- NCT00464334
- Testing
- V950, ISCOMATRIX™
- Volunteers
- 86 people
- Sponsor
- Merck Sharp & Dohme LLC
Posttraumatic Stress Disorder
Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD
The goal of this clinical trial is to learn if MDMA in combination with therapy is safe and effective in people with chronic, treatment-resistant PTSD.
- Trial name
- NCT01793610
- Testing
- Comparator Dose (40mg) MDMA HCl, Active Dose 2 (100 mg) MDMA HCl, Active Dose 1 (125 mg) MDMA HCl
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Resilient Pharmaceuticals
Alzheimer's Disease
3-month Study of MSDC-0160 Effects on Brain Glucose Utilization, Cognition & Safety in Subjects With Alzheimer's Disease
This study will evaluate the effect of 150 mg MSDC-0160 taken daily for 90 days compared to the effect of placebo on changes in brain glucose utilization using FDG-PET and cognition in older persons with mild Alzheimer's disease.
- Trial name
- NCT01374438
- Testing
- MSDC-0160
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- Metabolic Solutions Development Company
End Stage Renal Disease
SPIRIT for Persons With Dementia and Complex Multimorbidity
In this study, 30 patient and caregiver dyads will be randomized to receive the SPIRIT-dementia intervention or usual care. Participants will be follow-up with 2-3 days after the intervention to evaluate the impact of SPIRIT on…
- Trial name
- NCT04108000
- Testing
- SPIRIT-Dementia, Usual Care
- Where
- 4 sites in United States
- Volunteers
- 38 people
- Sponsor
- Emory University