Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder
Study of Fluconazole in Children With Autism Spectrum Disorder
Antifungal therapy is widely used for individuals with Autism Spectrum Disorders (ASD). The current investigation will examine the effects of fluconazole on behavioral functioning among children with ASD.
- Trial name
- NCT00936182
- Testing
- Fluconazole
- Where
- 3 sites in United States
- Volunteers
- 50 people
- Sponsor
- The Center for Autism and Related Disorders
Autism Spectrum Disorder
MRI Study of Subjects with ASD, Their Relatives and TD
This project is structured around a central study called "Study of genetic factors involved in autism and related conditions ("Genes and Autism" study, sponsor: INSERM).
- Trial name
- NCT05470088
- Testing
- Neuroimaging (MRI)
- Where
- 2 sites in France
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Autism Spectrum Disorder
Age-related Changes in Myeloarchitectonics Across Adulthood in Autism Spectrum Disorder
There is increasing awareness in the Autism Spectrum Disorder (ASD) research field about the deficit of knowledge with regard to the neurobiological, cognitive, and behavioral changes that occur in adults with ASD across the…
- Trial name
- NCT04108312
- Testing
- Anatomical MRI Scan
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Language Development Disorders, Autism Spectrum Disorder
Parent-Level Predictors of Early Language Interaction Quality and Intervention Outcomes
Children with poor early language skills are at risk for academic, social, vocational, and health difficulties across the lifespan.
- Trial name
- NCT03525951
- Testing
- Enhanced Milieu Teaching, no intervention comparison group
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder
Early Connections, Early Detection and Intervention in Infants at Risk for Autism
Early connections has two broad goals: to identify risk indices for autism spectrum disorder (ASD) in 6 to 24 month old infants who have an older sibling with ASD or infants who have an older neurotypical sibling.
- Trial name
- NCT00947700
- Testing
- Assessment, Monitoring & Intervention
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Washington
Pervasive Development Disorders
Guanfacine for the Treatment of Hyperactivity in Pervasive Developmental Disorder
The purpose of this study is to determine whether guanfacine (trade name Intuniv) by itself or in combination with methylphenidate (also known as Ritalin) is helpful for treating hyperactivity in children and adolescents with a…
- Trial name
- NCT01238575
- Testing
- extended-release guanfacine
- Where
- 5 sites in United States
- Volunteers
- 62 people
- Sponsor
- Yale University
Autism Spectrum Disorder, Functional Gastrointestinal Disorders
Low-FODMAP Diet and Probiotics: Effects on Gut, Behavior, and Microbiota in Children With Autism Spectrum Disorder
The goal of this clinical trial was to evaluate whether a low-FODMAP diet and probiotic supplements could reduce gastrointestinal (GI) symptoms and behavior problems in children with autism spectrum disorder (ASD) who also…
- Trial name
- NCT07086157
- Testing
- Probiotic, Low-FODMAP Diet
- Where
- Turkey (Türkiye)
- Volunteers
- 16 people
- Sponsor
- Marmara University Pendik Training and Research Hospital
Autism Spectrum Disorder, Autism
Internet-delivered Cognitive-Behavioral Therapy for Adolescents With Autism and Anxiety
Anxiety is very common in autistic youth. Cognitive behavioral therapy (CBT) is the recommended treatment for both autistic and typically-developing (TD) youth with anxiety, yet most families cannot access CBT due to cost…
- Conditions
- Autism Spectrum Disorder, Autism, Anxiety, Anxiety Disorders
- Trial name
- LUNA-A (NCT06537128)
- Testing
- LUNA-Adolescent, Treatment as Usual
- Where
- United States
- Volunteers
- 139 people
- Sponsor
- Baylor College of Medicine
Autistic Disorder
A Study of Pregnenolone in the Treatment of Individuals With Autism
This study will assess the tolerability and effectiveness of pregnenolone in the treatment of behavioral deficits in adults with autism.
- Trial name
- NCT01881737
- Testing
- Pregnenolone
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Measurement of vanilloïd Compounds in Urin of Autistic vs Control Patients, as Potential Biomarkers
In a former study, four vanilloid compounds were observed increased in the urin of autistic patients. The present study is aimed at performing a ambispective study to confirm or not these preliminary results.
- Trial name
- DIADAUVEDA (NCT04651972)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
ASD
Omega-3, Autism Spectrum Disorder (ASD)
This is a 12 week study to investigate the effects of omega-3 polyunsaturated fatty acids (PUFAs) in youth with autism spectrum disorder (ASD).
- Trial name
- OMeASD (NCT07365553)
- Testing
- Omega-3
- Where
- Taiwan
- Volunteers
- 50 people
- Sponsor
- China Medical University Hospital
Autism
Study to Evaluate the Efficacy and Safety of Aripiprazole
To evaluate the efficacy of flexibly dosed aripiprazole in reducing serious behavioral problems in Asian children and adolescents with a diagnosis of autism spectrum disorder, as measured by change from baseline to endpoint on…
- Trial name
- NCT02069977
- Testing
- Aripiprazole
- Where
- 6 sites in Philippines, South Korea and 1 more
- Volunteers
- 79 people
- Sponsor
- Yoo-Sook Joung
Autistic Disorder
Efficacy of Stellate Ganglion Block in Children With Autistic Disorder
The goal of this clinical trial is to explore efficacy of stellate ganglion block Children with Autistic Disorder. The main question it aims to answer is: Can stellate ganglion block improve the Autistic Disorder in children?…
- Trial name
- SGB-gudu (NCT06228157)
- Testing
- Routine therapy, Stellate ganglion block
- Where
- China
- Sponsor
- Zeng Changhao
Attention Deficit Hyperactivity Disorder, Autism Spectrum Disorder
Evaluation of the Effect and Safety of Lisdexamfetamine in Children Aged 6-12 With ADHD and Autism
The purpose of this study is to evaluate the effect and safety of Lisdexamfetamine dimesylate (Vyvanse®) in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) in children and adolescents with ADHD and comorbid…
- Trial name
- NCT03337646
- Testing
- Lisdexamfetamine Dimesylate
- Where
- Canada
- Volunteers
- 48 people
- Sponsor
- JPM van Stralen Medicine Professional
Autism Spectrum Disorder
Optimizing Social and Communication Outcomes for Toddlers With Autism
This project will examine the efficacy of two different treatment approaches aimed at facilitating change in social and communications outcomes of toddlers with autism.
- Trial name
- NCT00999778
- Testing
- Caregiver-Mediated Intervention, Caregiver-Education Intervention
- Where
- United States
- Volunteers
- 86 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Autism Spectrum Disorder (ASD
RCT of SCERTS (Social Communication, Emotional Regulation, Transactional Support) Program for Children With Autism Spectrum Disorder
This randomized control trial aims to assess the efficacy of the SCERTS intervention in children aged 3-6 years diagnosed with mild to moderate Autism Spectrum Disorder (ASD).
- Trial name
- NCT06733324
- Testing
- SCERTS (Social Communication, Emotional Regulation, Transactional Support), Behavioral Treatment, Speech Therapy
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Aisha Saleem
Neuropsychiatric Syndrome, Autism Spectrum Disorder
Nature and Animal-assisted Activities
Neuropsychiatric impairments in young adults are common and can involve social withdrawal, and difficulties in receiving support from healthcare and municipal social care services.
- Trial name
- NCT06431126
- Testing
- Nature and animal-assisted activities
- Where
- Sweden
- Volunteers
- 13 people
- Sponsor
- Kronoberg County Council
Autism Spectrum Disorder
The Effectiveness of an Attention-based Intervention for School Aged Autistic Children With Anger Regulating Problems
Children on the autism spectrum often show aggressive behavior. Treatment can train children to be more aware of their emotions.
- Trial name
- NCT05221515
- Testing
- Anger can go!, Parent psycho-education
- Where
- 2 sites in Netherlands
- Volunteers
- 51 people
- Sponsor
- VU University of Amsterdam
Autism Spectrum Disorder
A Trial To Evaluate The Efficacy of Magnetic Resonant Therapy in Autism
The purpose of this study is to show that a magnetic field applied to the front part of the brain of children suffering from Autism Spectrum Disorder(ASD) can improve function and ameliorate symptoms.
- Trial name
- NCT01985308
- Testing
- Magnetic Resonance Therapy (MRT)-Active
- Where
- 2 sites in United States
- Volunteers
- 28 people
- Sponsor
- Wave Neuroscience
Autism Spectrum Disorder
Promoting Resilience in Teens With ASD
Interventions for Autism Spectrum Disorder (ASD) are almost uniformly costly and time-intensive, blunting dissemination of intervention and stymying opportunities to make scalable impact.
- Trial name
- PRITA (NCT04208425)
- Testing
- Project Personality, Sharing Feelings Intervention
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Stony Brook University
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