Clinical trials: Pervasive Development Disorders
Autism, Autism Spectrum Disorder (ASD)
ScanBrit Dietary Intervention in Autism
A growing body of research indicates that dietary intervention excluding foods containing the proteins, gluten and casein, from the diet of children diagnosed with an autism spectrum disorder (ASD) may have a positive effect on…
- Trial name
- ScanBrit (NCT00614198)
- Testing
- Gluten- and casein-free diet
- Volunteers
- 72 people
- Sponsor
- Center for Autisme, Denmark
Autism, Neuroleptic Treatment
Use of Pharmacogenetics in the Treatment of Children With Autistic Spectrum Disorders
Children with autism are often treated with psychiatric drugs. These medications have been shown to improve their language and social function, and are important in improving their quality of life.
- Trial name
- NCT00859664
- Testing
- Genotyping of Cytochrome P450
- Where
- Israel
- Volunteers
- 500 people
- Sponsor
- Assaf-Harofeh Medical Center
Autism Spectrum Disorder, Social Communication Challenges
Promoting Inclusive Educational Environments for Children with Autism and Other Social-communication Challenges: Preschool Class and Primary School
This study evaluates the effect of using the Autism Program Environment Rating Scale (APERS) as the foundation for providing feedback, in-service training and coaching to teachers, to improve program quality for autistic (ASD)…
- Trial name
- NCT05509309
- Testing
- APERS-based model
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Autism
CBT for Youth With Autism and Emotional/Behavioral Needs in Community Care Settings
This study is a 4-year randomized, controlled trial comparing cognitive behavioral therapy (CBT) to usual clinical care for children (aged 6-14 years) with autism and emotional dysregulation (e.g., irritability, anxiety).
- Trial name
- CYAN (NCT05031364)
- Testing
- Behavioral Interventions for Anxiety in Children with Autism (BIACA), Treatment-as-Usual Supplemented by Internet-Based Self-Instruction (MEYA)
- Where
- 3 sites in United States
- Volunteers
- 100 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Intranasal Oxytocin in Youth With Autism
Growing evidence demonstrates the critical contribution of the neuropeptide oxytocin in the development and maintenance of autism, due to its role in social behaviour and learning processes.
- Trial name
- NCT05934812
- Testing
- Oxytocin nasal spray
- Where
- Norway
- Volunteers
- 128 people
- Sponsor
- Oslo University Hospital
Autistic Spectrum Disorder
Effect of Therapeutic Diet With Physiotherapy on Gross Motor and Cognition of Autistic Children
: A clinical trial will be conducted to investigate the effect of free-gluten/ casein diet along with specific physiotherapy program on gross motor development and cognitive function in 3-12 years old children with ASD, And thus…
- Trial name
- NCT06086964
- Testing
- therapeutic diet., physiotherapy
- Where
- Saudi Arabia
- Volunteers
- 80 people
- Sponsor
- University of Jazan
Autism
Parents of Newly Diagnosed Preschool Children With Autism Spectrum Disorder:
Manitoba parents of preschool children newly diagnosed with Autism must wait up to a year to receive government funded services for their child.
- Trial name
- NCT03005431
- Testing
- Parent training and support
- Volunteers
- 60 people
- Sponsor
- University of Manitoba
Autism
Testing a Novel Speech Intervention in Minimally Verbal Children With Autism Spectrum Disorder (ASD)
The goal of the Novel Language Intervention for minimally verbal children with Autism Spectrum Disorder (ASD) is to test the efficacy of one experimental treatment (AMMT) compared to baseline assessments and compare the AMMT…
- Trial name
- NCT03015272
- Testing
- Auditory-Motor Mapping Training, Speech-Repetition Therapy
- Where
- 2 sites in United States
- Volunteers
- 14 people
- Sponsor
- Beth Israel Deaconess Medical Center
Autistic Disorder
Use of a Family Navigator in Families With Children Newly Diagnosed With Autism Spectrum Disorder
The purpose of this study is to see whether or not Family Navigators, who 1 ) help families after their child is diagnosed with autism and help them get autism specific services for their child 2) help families identify barriers…
- Trial name
- NCT01340092
- Testing
- Family Navigator
- Where
- United States
- Volunteers
- 192 people
- Sponsor
- Boston Medical Center
Autism Spectrum Disorder
REGulatory T Cells in Autism Induced by Maternal Immune Activation
Autism Spectrum Disorders (ASD) represent a heterogeneous clinical entity of neurodevelopmental disorders affecting around 1% of the general population (Lord et al. 2020).
- Trial name
- REGAIN (NCT06169111)
- Testing
- REGulatory T cells in Autism induced by maternal Immune activation
- Where
- France
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Autism Spectrum Disorder (ASD)
Cycling Interventions on Cognition in Children With Autism
The goal of this clinical trial was to determine if a specific type of cycling exercise improved executive functions in school-aged children with autism spectrum disorder (both boys and girls, aged 8-10 years, no healthy…
- Trial name
- Cycling&Autism (NCT07295912)
- Testing
- Learning to Bicycle, Bicycle Treadmill, Cycling with Training Wheels
- Where
- Hong Kong
- Volunteers
- 62 people
- Sponsor
- Chinese University of Hong Kong
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Autism
Multisensorial Information's Treatment in Autism Spectrum Disorder
Introduction: Autism spectrum disorder is characterized by deficits in three functional domains: language and communication, social reciprocity, and the presence of restricted interests/repetitive behaviors.
- Trial name
- NCT02579109
- Testing
- memory test
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Smith-Magenis Syndrome, Autism Spectrum Disorder
Smith Magenis Syndrome and Autism Spectrum Disorders
Autism Spectrum Disorders (ASD) are a neurodevelopmental disorder. Their prevalence is estimated at around 0.4% of the general population worldwide.
- Trial name
- SMS/TSA (NCT05116904)
- Testing
- Assessment
- Where
- 2 sites in France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Irritability Associated With Autism Spectrum Disorder
Brexpiprazole in Treatment of Children and Adolescents With Irritability Associated With Autism Spectrum Disorder for Subjects That Have Completed Participation in 331-201-00148
The purpose of this study is to evaluate the long-term safety and tolerability of brexpiprazole in children and adolescent participants, aged 5 to 17, with irritability associated with autism spectrum disorder.
- Trial name
- NCT04258839
- Testing
- Brexpiprazole
- Where
- 28 sites in United States
- Volunteers
- 95 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Autism Spectrum Disorder
Building Resilience and Appropriate Independence in Young Adults With Autism
This study evaluates the effects of a 12-week life-skills resilience curriculum for young adults with autism. The project utilizes a cohort single arm design.
- Trial name
- NCT03842332
- Testing
- Life Skills and Resilience Program
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of California, San Francisco
Autism Spectrum Disorder
Acupressure and Acupuncture as an Intervention With Children With Autism II
The purpose of this study is to see if children with autism spectrum disorder (ASD) will tolerate an acupressure and acupuncture intervention twice weekly over a 3 month period of time that targets regulatory and behavioral…
- Trial name
- NCT00935701
- Testing
- Acupressure and Acupuncture
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Autism Spectrum Disorder, Neurodevelopmental Disorders
A Smart Toy for Motor Function and Early Assessment of Children With Possible Autism
Autism diagnostic referrals across the UK have doubled within the last five years. Covid-19 has further delayed diagnostic pathways, while innovation has not kept pace in assisting clinical teams with low cost, fast, and…
- Trial name
- Tangiball (NCT04980677)
- Testing
- Tangiball
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sussex Community NHS Foundation Trust
Executive Function of School-aged Children With ASD
VR Executive Training of School-aged Children With ASD
Many studies support that children with autism spectrum disorder (ASD) show executive dysfunction. The applicant's NSC project report also indicated that in all areas in the behavior rating inventory of executive function, the…
- Trial name
- NCT06130293
- Testing
- VR game intervention
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- National Taiwan Normal University
Pervasive Developmental Disorder
Assessment of Factors Which Predict Improvement in Children With PDD After a Year of Integrative Therapy
The aim of the current research is to assess the efficiency of the Integrative Therapy among children with PDD after a year of treatment in kindergartens in Ashdod, Israel.
- Trial name
- NCT00531830
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- BeerYaakov Mental Health Center