Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorders
Telehealth Coaching for Families of Children With Autism
The purpose of this study is to investigate the efficacy of a 12 week telehealth intervention for families of children with autism spectrum disorders under the age of 6 years on child participation and parent efficacy.
- Trial name
- NCT02928068
- Testing
- Occupational Performance Coaching (OPC)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Autism Spectrum Disorder
Modifying (Phase I) and Evaluating (Phase II) Virtual Reality Job Interview Training for Youth in Transition
The unemployment rate is quite high among adults with an autism spectrum disorder (ASD). Inadequate transition planning during high school and gaps between vocational needs and availability of evidence-based services help explain…
- Trial name
- NCT03514134
- Testing
- Virtual Reality Job Interview Training, Services as Usual
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- University of Michigan
Autistic Disorder
Research in Autism: Parent Intervention
The purpose of this research project was to systematically compare two widely used types of intervention programs for children with autism within a parent training model.
- Trial name
- NCT01258465
- Testing
- Pivotal Response Training, Picture Exchange Communication System
- Where
- 2 sites in United States
- Volunteers
- 39 people
- Sponsor
- University of California, San Diego
Autism Spectrum Disorder
Effect of an 8-Week Pickleball Program for Adults With Autism: A Feasibility Trial With a Delayed-Control Design
The goal of this clinical trial is to learn if an 8-week, community-based pickleball program can improve sensory-motor function and reduce the severity of core autism symptoms in adults ages 18-45 with autism spectrum disorder…
- Trial name
- NCT07432776
- Testing
- Pickleball Program (Community-Based)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Penn State University
Autism Spectrum Disorders
Brain Mechanisms for Language Processing in Adolescents With Autism Spectrum Disorder
The main goal of our study is to find out why some people with Autism Spectrum Disorder (ASD) do not develop verbal abilities or remain minimally-verbal throughout adolescence and adulthood.
- Trial name
- BSL (NCT02700074)
- Testing
- No Intervention
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Autism, Parenting
The Effects of an Empowerment Program for Parents of Children With Autism
This study aims to evaluate the effectiveness of an empowerment program that includes both parent training and motivational interviewing for parents of children with autism, supporting their competence in the care of their…
- Conditions
- Autism, Parenting, Motivational Interviewing
- Trial name
- NCT06629974
- Testing
- Parental empowerment program
- Where
- Turkey (Türkiye)
- Volunteers
- 69 people
- Sponsor
- Manisa Celal Bayar University
Autism Spectrum Disorder
Autism Access Link for Early Referral and Treatment
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- Autism ALERT (NCT04861740)
- Testing
- Autism ALERT, Screening Intervention
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Autistic Disorder, Behavioral Symptoms
Study of Aripiprazole in the Treatment of Serious Behavioral Problems in Children and Adolescents With Autistic Disorder (AD)
This study will provide long-term safety data for patients who are taking aripiprazole for up to 1 year. Most patients enrolled in this study will have participated in a short-term study with aripiprazole (CN138-178 [NCT00332241]…
- Trial name
- NCT00365859
- Testing
- Aripiprazole
- Where
- 55 sites in United States
- Volunteers
- 330 people
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Oppositional Defiant Disorder, Conduct Disorder
Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.
This study was developed in order to assess the effects of risperidone (Risperdal) as compared with placebo on cognitive-motor performance (attention, memory, and hand steadiness) and body movements.
- Conditions
- Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit/Hyperactivity Disorder (ADHD), Intermittent Explosive Disorder
- Trial name
- NCT00399698
- Testing
- Risperdal
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Ohio State University
Autism
Adaptive Interventions for Minimally Verbal Children With ASD in the Community
Adaptive Interventions for Minimally Verbal Children with ASD in the Community, seeks support to construct an adaptive intervention that utilizes two efficacious interventions (JASP-EMT and CORE- DTT) that have shown promise for…
- Trial name
- AIM-ASD (NCT01751698)
- Testing
- JASP-EMT, DTT
- Where
- 4 sites in United States
- Volunteers
- 192 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder, Behavior
Pilot Trial of the RUBI Program for Autistic Adults
The goal of this clinical trial is to evaluate if a redesigned version of the RUBI parenting intervention can reduce challenging behaviors and improve adaptive skills in autistic adults with co-occurring challenging behaviors.
- Conditions
- Autism Spectrum Disorder, Behavior, Parenting
- Trial name
- RUBI-A (NCT06593613)
- Testing
- RUBI-A, R-ISLEA
- Where
- 3 sites in United States
- Volunteers
- 80 people
- Sponsor
- Seattle Children's Hospital
Autism Spectrum Disorder
A Novel Framework for Impaired Imitation in ASD
There is long-standing recognition that people with autism spectrum disorders (ASD) have difficulty imitating others' actions; some investigators have highlighted impaired imitation as being a core contributor to the development…
- Trial name
- NCT03423160
- Testing
- None--observational
- Where
- United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
Autistic Disorder
A Chart Review to Evaluate the Safety and Efficacy of MeRT on Subjects With ASD
The purpose of this study is to evaluate the safety and efficacy of Magnetic EEG/ECG-Guided Resonance Therapy (MeRT) on subjects with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02758496
- Testing
- MeRT Efficacy Chart Review
- Where
- United States
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Wave Neuroscience
Autistic Disorder
Intranasal Dexmedetomidine vs Oral Triclofos Sodium for EEG in Children With Autism
Children with Autistic Spectrum Disorder (ASD) often undergo an Electroencephalography (EEG) as part of routine work up. These children present a challenge to successful EEG execution, due to a lack of co-operation, and thus, are…
- Trial name
- NCT04270708
- Testing
- Dexmedetomidine, Triclofos 100 MG/ML
- Volunteers
- 200 people
- Sponsor
- Rabin Medical Center
Autism, Cerebral Palsy
Near-infrared Spectroscopy and Electroencephalography to Assess Cortical Activation During Motor Tasks in Infants and Toddlers With and Without Cerebral Palsy
Background: New ways to study the brain as people move include near-infrared spectroscopy (NIRS) and electroencephalography (EEG).
- Trial name
- NCT03434080
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Autism Spectrum Disorder
Emergence of Generative Language
The purpose of this study is to investigate the effects of several applied behavior teaching procedures on the use of multi-word utterances by children with autism.
- Trial name
- NCT02555241
- Testing
- Mand Training, Matrix, Stimulus Equivalence Training
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder
Feasibility of Using Telepractice to Provide Modified Interaction Guidance.
The purpose of this study is to determine the feasibility of using telepractice to provide Modified Interaction Guidance (MIG) to caregivers and their child with autism.
- Trial name
- NCT03972254
- Testing
- Modified Interaction Guidance
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
Autism Spectrum Disorder
Evaluation of Transcranial Photobiomodulation in Autism Spectrum Disorder
The purpose of this 8-week double-blind randomized placebo-controlled study is to assess the tolerability, safety, and efficacy of tPBM in adult patients with ASD.
- Trial name
- NCT05363982
- Testing
- Transcranial Photobiomodulation (tPBM)
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Massachusetts General Hospital
Autism, Children
Biomarker of Children With Familial Autoimmune History
The purpose of this study is to identify biomarkers in this subset of autism patients, design a protein based assay system for screening serum for these biomarkers and confirm that these serum antibodies are still present at one…
- Trial name
- NCT01541033
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Le Bonheur Children's Hospital
Fragile X Syndrome
A Safety Study of NNZ-2566 in Patients With Fragile X Syndrome
The purpose of this study is to determine whether NNZ-2566 is safe and well tolerated in the treatment of Fragile X Syndrome in adolescent and adult males.
- Trial name
- NCT01894958
- Testing
- NNZ-2566
- Where
- 17 sites in United States
- Volunteers
- 72 people
- Sponsor
- Neuren Pharmaceuticals Limited
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