Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorders
Parent-supported Social Skills Training for Teens With Autism Spectrum Disorders (PEERS-K)
This study aims to develop a parent-assisted social skills training program for adolescents with autism spectrum disorder(ASD) and verify therapeutic effects of the program through case-control study. 1.
- Trial name
- NCT01501058
- Testing
- parent-assisted social skills training program for adolescents with autism spectrum disorder, Delayed intervention
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Seoul National University Hospital
Autism Spectrum Disorder
Emergent Multi-Class Imitation Training
The goals of this project are to (a) incorporate empirical findings on imitation training and learning in autistic children into a comprehensive protocol for Applied Behavior Analysis practitioners designed to rapidly facilitate…
- Trial name
- EMIT (NCT05849376)
- Testing
- Emergent Multi-Class Imitation Training
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Rutgers, The State University of New Jersey
ASD, Autism Spectrum Disorder
Theta Burst Stimulation for Refractory Depression in Autism Spectrum Disorder
Evaluate the efficacy of accelerated theta burst stimulation (aTBS) in reducing depressive symptoms in autism spectrum disorder (ASD)
- Conditions
- ASD, Autism Spectrum Disorder, Autism, Depression - Major Depressive Disorder
- Trial name
- RETSORE-RCT (NCT06670040)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Autism
Psychophysiological Effects of Lactobacillus Plantarum PS128 in Preschool Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) comprises a complex group of disorders of neuronal development characterized by social and communication impairment along with presence of repetitive and restrictive behaviors.
- Trial name
- NCT03982290
- Testing
- Probiotic, Lactobacillus plantarum PS128
- Where
- Taiwan
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Mackay Memorial Hospital
Autism Spectrum Disorder, Autism
In-Person Mindfulness-based Intervention for Adolescents With Autism Spectrum Disorder and Their Caregivers
Adolescents with ASD often have co-occurring mental health symptoms like stress, anxiety, and depression. The investigators are conducting this research study to develop interventions for adolescents with ASD that will improve…
- Trial name
- NCT06577623
- Testing
- MINDful TIME
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder, Developmental Disability
Propranolol for Challenging Behaviors in Autism
Severe challenging behaviors such as aggression and self-injury can cause significant morbidity and decrease the quality of life for individuals with Autism Spectrum Disorders (ASD).
- Conditions
- Autism Spectrum Disorder, Developmental Disability, Aggression, Self-Injurious Behavior
- Trial name
- NCT04047355
- Testing
- Propranolol
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rutgers, The State University of New Jersey
Autism Spectrum Disorder
Effects of Receptive Language Intervention vs Individual Therapy for Preschool Children With Autism Spectrum Disorder.
Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and social interaction and the presence of restricted, repetitive behaviors.
- Trial name
- NCT06927518
- Testing
- Receptive language intervention by using the total communication
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Autism ALERT Expansion
Autism Access Link for Early Referral and Treatment [ALERT], the intervention proposed in this application, is a novel state-wide referral and case management platform that PCPs can activate to ensure that a child with suspected…
- Trial name
- NCT06246890
- Testing
- Autism ALERT
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- Oregon Health and Science University
Autism, Neurodevelopment
Reciprocal Innovation to Optimize Low-Tech Augmentative and Alternative Communication (AAC) for Individuals
Many people with autism and other developmental conditions have difficulty speaking or do not use speech and need other ways to communicate.
- Trial name
- AAC (NCT07581483)
- Testing
- Automated AAC Assessment and Low-Tech AAC Implementation Support, Standard AAC Support
- Where
- 2 sites in United States, Kenya
- Volunteers
- 500 people
- Sponsor
- Indiana University
Autism Spectrum Disorders, Non-verbal Learning Disorder
Comparison of ABLLS-R and Portage Guide in the Development of Receptive Language Skills Autism Spectrum Disorder.
Language is the system someone uses to communicate with another person. This covers the origins and construction of words, their definitions, and the use of language in various contexts.
- Trial name
- NCT06292520
- Testing
- Portage Guide Protocol, ABLLS-R protocol
- Where
- Pakistan
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Autism Spectrum Disorder
Neurofeedback Therapy for Children Diagnosed With Autism
This project aims: to further explore the effectiveness of a novel sonified Neurofeedback management therapy for children diagnosed with Autism Spectrum Disorder (ASD) to determine if balance control is different before and after…
- Trial name
- NCT02773303
- Testing
- Mente Autism™
- Where
- United States
- Volunteers
- 83 people
- Sponsor
- Carrick Institute for Graduate Studies
Noncompliance
Efficacy of Parent-Child Interaction Therapy With Autism Spectrum Disorder
The aim of the current proposal is to determine if the PCIT treatment manual can be successfully utilized for preschoolers with ASD and disruptive behavior (across a range of intellectual functioning levels) and to evaluate its…
- Trial name
- PCIT (NCT02088905)
- Testing
- Parent Child Interaction Therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Autism Spectrum Disorder
Evaluation of Social ABCs With Attention Training Intervention for Toddlers With Suspected Autism
The Social ABCs is an evidence-based, developmentally informed, caregiver-mediated behavioural intervention for toddlers with suspected or confirmed Autism Spectrum Disorder (ASD).
- Trial name
- NCT03215394
- Testing
- Attention Training Program, Social ABCs, Treatment As Usual
- Where
- 4 sites in Canada, United Kingdom
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Holland Bloorview Kids Rehabilitation Hospital
Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity
Where Wild Things Grow: Nature- and Activity-based Group Interventions for Neurodivergent Children and Youth
The goal of this action research project is to develop and implement nature- and activity-based group interventions across health care, school and leisure settings in Southern Norway.
- Conditions
- Neurodevelopmental Outcomes, ADHD - Attention Deficit Disorder With Hyperactivity, Autism, Tourette Syndrome
- Trial name
- NCT07203469
- Testing
- Universal approach, Selective approach, Outdoor therapy
- Where
- 2 sites in Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Sorlandet Hospital HF
Autism Spectrum Disorder
Mobile App-Based Intervention to Improve Toothbrushing in Children and Teens With Autism
The goal of this clinical trial is to test whether the autism-friendly app improves toothbrushing outcomes compared to a control app with only a digital mirror and countdown timer among children and teens (ages 8-17 years) with…
- Trial name
- BU (NCT07446413)
- Testing
- Brush Up App, Brush Down App
- Where
- United States
- Volunteers
- 270 people
- Sponsor
- University of Washington
Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) in Children With Autism Spectrum Disorder
Paediatric Autism Communication Therapy (PACT) is a naturalistic developmental behavioural interventions to reduce autism symptoms.
- Trial name
- DAN-PACT (NCT05673096)
- Testing
- PACT, MAU
- Where
- 6 sites in Denmark
- Volunteers
- 280 people
- Sponsor
- University of Southern Denmark
DDX3X, Mental Retardation, X-linked 102
DDX3X Syndrome -The Seaver Autism Center for Research and Treatment is Characterizing DDX3X-related Neurodevelopmental Disorders Using Genetic, Medical, and Neuropsychological Measures.
DDX3X syndrome is a genetic cause of intellectual disability and other neurologic features including, in some cases, autism. Variants in the DDX3X gene are thought to account for 1-3% of unexplained intellectual disability in…
- Conditions
- DDX3X, Mental Retardation, X-linked 102, Autism Spectrum Disorder
- Trial name
- NCT03718910
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Autistic Disorder
An Evaluation of a Developmentally-Based Parent Training Program for Children With Autism
The purpose of this study is to assess the efficacy of a parent training program in the treatment of social and communication deficits in children with autism.
- Trial name
- NCT01400269
- Testing
- Pacific Autism Center for Education (PACE ) developmentally based parent delivered intervention
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- Stanford University
Autism Spectrum Disorder
Open Label, Adaptive, Parallel Group PET Study Using RO7017773 And [11C] RO15-4513
This is a single dose (SD), non-randomized, open-label, adaptive, parallel group study with the purpose of investigating the occupancy of alpha5-containing GABAA receptors by RO7017773 in healthy participants.
- Trial name
- NCT03507569
- Testing
- RO7017773, [11C] Ro15-4513
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Stress
"ACT" for Parents of Children With Autism Spectrum Disorder
The investigators will develop and pilot test an intervention called "ACT for Parents" which aims to decrease stress and improve quality of life in parents of children < 15 years who have a diagnosis of autism spectrum disorder.
- Trial name
- NCT02255786
- Testing
- Acceptance and Commitment Therapy
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Massachusetts General Hospital
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