Clinical trials: Pervasive Development Disorders
Efficacy of PEGASUS
Evaluating PEGASUS - a Group Intervention for Young People With an Autism Spectrum Disorder
When a clinician gives an autism spectrum disorder (ASD) diagnosis they hope this will be helpful to the person receiving it and their family.
- Trial name
- NCT01187940
- Testing
- PEGASUS
- Where
- United Kingdom
- Volunteers
- 40 people
- Sponsor
- Institute of Child Health
Autistic Disorder, Asperger Syndrome
Study of Aripiprazole to Treat Children and Adolescents With Autism
The purpose of this open label study in children and adolescents is to examine the acute and long-term effects of aripiprazole on problem behaviors associated with autism spectrum disorders and development in areas which appear…
- Conditions
- Autistic Disorder, Asperger Syndrome, Autism Spectrum Disorder
- Trial name
- PAIRS (NCT00619190)
- Testing
- aripiprazole
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Repetitive Compulsive Behavior
Family-Implemented Treatment on the Behavioral Inflexibility of Children With Autism
The overall goal of this project is to determine whether a new form of family-based treatment for repetitive and inflexible behaviors, delivered using videoconferencing technology, can counter any negative effects of those…
- Trial name
- FITBI (NCT05125003)
- Testing
- FITBI, Parental Education
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Autism, Autism Disorder
Using Virtual Reality to Improve Emotion Understanding in Children With Autism
Autism Spectrum Disorders (ASD) are neurodevelopmental conditions characterized by difficulties in social interaction, communication, and in understanding one's own and others' mental and emotional states.
- Trial name
- NCT07367256
- Testing
- Oculus intervention, Traditional intervention
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- Istituto per la Ricerca e l'Innovazione Biomedica
Autism Spectrum Disorder, Bone Diseases, Developmental
Bone Mass Accrual in Children With Autism Spectrum Disorder
This is a observational study to investigate the degree to which bone mineral density is impaired in boys with autism compared with typically developing controls.
- Trial name
- NCT03162445
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Autism Spectrum Disorder
Generalized Training Program for Caregivers on the ESDM: PEGASE
The main objective of the study is to evaluate the effectiveness of a parent's training program (name PEGASE) of young children (aged 2 to 4 years) with Autism Spectrum Disorders.
- Trial name
- PEGASE (NCT03769571)
- Testing
- Parental coaching program at ESDM (P-ESDM)
- Where
- France
- Volunteers
- 30 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Autism Spectrum Disorder
Use Music Therapy In Autism Spectrum Disorder
Music therapy is an established form of creative art therapy. By using music as a specific medium of communication, expression and adapting it to the individual resources and abilities of the patient, music therapy can be…
- Trial name
- NCT03267095
- Testing
- music therapy sessions .
- Volunteers
- 60 people
- Sponsor
- Assiut University
Autism Spectrum Disorder, Major Depressive Disorder
rTMS for Depression in Young Adults With Autism
The current clinical trial is focused on evaluating the efficacy of rTMS for treatment of depression in youth and young adults (hereafter called transition aged youth, TAY) with autism spectrum disorder (ASD).
- Trial name
- rTMS-MDD (NCT04972136)
- Testing
- Active Bilateral Theta Burst Stimulation
- Where
- Canada
- Volunteers
- 80 people
- Sponsor
- Centre for Addiction and Mental Health
Autism Spectrum Disorder
JASPER Implementation in NFLD
This study will focus on examining the supports required to enable community Senior JASPER Trainers to support the training and development of junior interventionists throughout the province of Newfoundland and Labrador, Canada.
- Trial name
- NCT03205475
- Testing
- Alternate Coaching and Video Feedback Phase 1, Weekly Coaching in Phase 1, Weekly Coaching plus Intensive Refresher Course Phase 2
- Where
- Canada
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Government of Newfoundland and Labrador
Autism Spectrum Disorder
Effectiveness and Implementation of a Mental Health Intervention for ASD
The purpose of this study is to test the effectiveness of training community mental health therapists to deliver a mental health intervention for ASD ("AIM HI") and study the process of implementing AIM HI in community mental…
- Trial name
- AIM HI (NCT02416323)
- Testing
- AIM HI Training
- Where
- United States
- Volunteers
- 609 people
- Sponsor
- University of California, San Diego
MONITOR, COACH
Promoting Early Intervention Timing and Attention to Language
The proposed study (PETAL: Promoting Early intervention Timing and Attention to Language) aims to determine the timing of intervention among infants with Increased Likelihood for Autism (ILA; at risk for autism by virtue of…
- Trial name
- PETAL (NCT05853861)
- Testing
- JASPER Babble
- Where
- 2 sites in United States
- Volunteers
- 140 people
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
Effects of Ayres Sensory Integration Therapy Versus Conservative Treatment in Autism Spectrum
Effects of Ayres Sensory Integration Therapy Versus Conservative Treatment in Autism Spectrum
- Trial name
- NCT06373770
- Testing
- Ayres sensory integration therapy, Behaviour Therapy
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Superior University
Autism, Autism Spectrum
Autologous Bone Marrow Stem Cells for Children With Autism Spectrum Disorders
The purpose of this study is to determine whether the plasticity of autologous intrathecal hematopoietic cells would improve the neurologic and the social skills of pediatric patients with autism spectrum disorders.
- Trial name
- Autism (NCT01740869)
- Testing
- Autologous Intrathecal Hematopoietic Stem Cells, Observation with IDEA and CARS Scales
- Where
- Mexico
- Volunteers
- 30 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Autism Spectrum Disorder
Effect of ESDM and PCIT-A in Autism Spectrum Disorder
Children with ASD often show disruptive behaviors. However, interventions that were specifically designed to improve these symptoms have not been sufficiently investigated, especially in children with level 1 to level 3 ASD.
- Trial name
- TAFF (NCT04722783)
- Testing
- Parent-Child-Interaction Therapy adapted for children with autism spectrum disorder (PCIT-A), Early Start Denver Model (ESDM) intervention, 1-hour ESDM
- Where
- Switzerland
- Volunteers
- 24 people
- Sponsor
- Bruno Rhiner
Autism Spectrum Disorder
Can a Novel Telemedicine Tool Reduce Disparities Related to the Identification of Preschool Children With Autism?
Families seeking evaluation for autism spectrum disorder (ASD) often face barriers such as low availability of specialists, lengthy waitlists, and long distances to tertiary care diagnostic centers.
- Trial name
- TAP-P (NCT05373173)
- Testing
- Tele-assessment + In-person assessment, Tele-assessment only
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Autism Spectrum Disorder (ASD)
Sensory-Motor Integration for Sensory Processing and Balance in ASD
This randomized controlled trial evaluates the effectiveness of a 16-week structured sensory-motor integration exercise program compared to conventional therapy (Applied Behavior Analysis and massage therapy) in improving sensory…
- Trial name
- SMIE-ASD (NCT06922422)
- Testing
- Sensory-Motor Integration Exercises, Conventional therapy group
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Assiut University
Sensory Disorders, Autism
Exposure Therapy for Auditory Sensitivity in Autism
Auditory hyper-reactivity affects up to 66% of children with autism spectrum disorder (ASD) and has been linked to greater stress and anxiety for children and their families.
- Conditions
- Sensory Disorders, Autism, Autism Spectrum Disorder, Autism With High Cognitive Abilities
- Trial name
- NCT03206996
- Testing
- Exposure therapy, Psycho-education, Caregiver education/home program development
- Where
- 2 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University of Florida
Autism Spectrum Disorder
Efficacy of Vivomixx on Behaviour and Gut Function in Autism Spectrum Disorder
The purpose of this study is to assess the effects of 3 months supplementation with the multi strain probiotic Vivomixx on the overall function, aberrant behaviours and frequency of gastrointestinal symptoms in children with…
- Trial name
- VIVO-ASD (NCT03369431)
- Testing
- Vivomixx
- Where
- United Kingdom
- Volunteers
- 69 people
- Sponsor
- University College, London
Autism, Autism Spectrum Disorder
Promoting Emotional and Autonomic Control Through Guided Breathing Exercises for Emerging Adults With Autism
This study examines the impact of guided breathing exercises on stress and heart rate variability (HRV) in autistic young adults.
- Trial name
- PEACE-A (NCT07238153)
- Testing
- Guided breathing exercise - SPB, Guided breathing exercise - HRV-BF
- Where
- 2 sites in Belgium
- Volunteers
- 68 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Autism Spectrum Disorder
NarraTivAS - Narrative Family Therapy in Autism Spectrum
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by difficulties in social communication and interaction, along with restricted and repetitive patterns of behavior, interests, or activities.
- Trial name
- NarraTivAS (NCT07246395)
- Testing
- Narrative Family Therapy, Family Game Theory-based Intervention
- Where
- Portugal
- Volunteers
- 63 people
- Sponsor
- University of Coimbra
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