Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder
Cognitively Enhanced Tai Chi for Executive Function in Children With Autism Spectrum Disorder
This study compares three exercise courses for children aged 8-11 years with autism spectrum disorder: Tai Chi with added cognitive challenges, standard Tai Chi, and general exercise.
- Trial name
- NCT07322952
- Testing
- Cognitively Enhanced Tai Chi, Standard Tai Chi, General Exercise
- Where
- China
- Volunteers
- 158 people
- Sponsor
- Jinan University Guangzhou
Autism Sibling, Autism Spectrum Disorder
Milieu Teaching-AV (MT-AV Pilot)
This project will look at whether a novel approach to language intervention that encourages looking to audiovisual speech cues for infants with autistic older siblings (Baby Sibs), who are highly likely be diagnosed with autism…
- Trial name
- MT-AV Pilot (NCT06794476)
- Testing
- Milieu Teaching-AV
- Where
- United States
- Sponsor
- Father Flanagan's Boys' Home
Autism Spectrum Disorder
The Effect of the Low Fodmap Diet in Children With Autism Spectrum Disorders
This study assesses the effect of the low fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP) diet on gastrointestinal (GI) and behavioral problems in children with autism spectrum disorder (ASD).
- Trial name
- NCT04054349
- Testing
- Low FODMAP diet
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Ohio State University
Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS)
Resting-State Functional Connectivity as a Predictor of tDCS Effects in Adolescents With Autism Spectrum Disorder
Background: Transcranial Direct Current Stimulation (tDCS) is a form of non-invasive brain stimulation that has aroused increased interests in the past decade.
- Conditions
- Autism Spectrum Disorder (ASD), Transcranial Direct Current Stimulation (tDCS), Electroencephalography
- Trial name
- NCT06878326
- Testing
- tDCS
- Where
- Hong Kong
- Volunteers
- 90 people
- Sponsor
- The Hong Kong Polytechnic University
Autistic Disorder
Motor Learning and Brain Changes in Autism
The purpose of this pilot study is to determine whether a video-game based motor training can affect postural stability, daily living skills, autism symptoms, and white matter microstructure of the corticospinal tract in…
- Trial name
- NCT02358317
- Testing
- Video Game Motor Training, Sedentary Video Game Training
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Autism Spectrum Disorder, ASD
Cord Blood Infusion for Children With Autism Spectrum Disorder
This is a single site, prospective, randomized, double-blind study of a single intravenous autologous or allogeneic, unrelated cord blood (CB) infusion in children ages 2-7 years with Autism Spectrum Disorder (ASD).
- Conditions
- Autism Spectrum Disorder, ASD, Autism, PDD
- Trial name
- Duke ACT (NCT02847182)
- Testing
- Cord Blood Infusion
- Where
- United States
- Volunteers
- 180 people
- Sponsor
- Joanne Kurtzberg, MD
Autism Spectrum Disorder, Food Selectivity
Clinical Trial of "Exploradores de Sabores" to Improve Food Selectivity in ASD Kids
The goal of this randomized, single-blind clinical trial is to evaluate the effectiveness of the Exploradores de Sabores parent-mediated nutrition intervention in reducing food selectivity and improving dietary variety, mealtime…
- Trial name
- NCT07727018
- Testing
- Exploradores de Sabores Parent-Mediated Nutrition Intervention, Education as Usual (EAU)
- Where
- Mexico
- Volunteers
- 72 people
- Sponsor
- Universidad Autonoma de Baja California
Autism Spectrum Disorder, Insomnia
Iron Treatment of Sleep Disorders in Children With Autism Spectrum Disorder
Autism Spectrum Disorders (ASD) are characterized by difficulties in language, social communication, and repetitive and restricted behaviors. ASD affects as many as 1 in 90-150 children.
- Trial name
- NCT01745497
- Testing
- Ferrous sulfate
- Where
- 4 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- University of Colorado, Denver
Autism Spectrum Disorder, Language Disorders
Early Treatment of Language Impairment in Young Children With Autism Spectrum Disorder With Leucovorin Calcium
The primary objective of this study is to evaluate the cognitive and behavioral effects of liquid leucovorin calcium on young children with autism spectrum disorder (ASD) and determine whether it improves language as well as the…
- Trial name
- NCT04060017
- Testing
- Levoleucovorin Calcium
- Where
- 2 sites in United States
- Volunteers
- 80 people
- Sponsor
- Southwest Autism Research & Resource Center
Autism Spectrum Disorder
Evaluating Bone Marrow Cell Transplant for Treating Cerebral Palsy From Brain Hypoxia
This clinical trial aims to evaluate the effectiveness of autologous bone marrow mononuclear cell transfusion in treating cerebral palsy caused by cerebral hypoxia.
- Trial name
- NCT06629324
- Testing
- Autologous Bone Marrow Mononuclear Cell Transfusion, Rehabilitation
- Where
- 2 sites in Vietnam
- Volunteers
- 58 people
- Sponsor
- Vinmec Research Institute of Stem Cell and Gene Technology
Autism Spectrum Disorder
Omic Profile in Autism Spectrum Disorder: From Cellular Level Towards Future Treatments
This is an interventional non pharmacological study in pediatric patientis affected by Autism Spectrum Disorder. It ams to create a collection of iPSCs and hiNSCs derived from deeply characterized ASD patients, to…
- Trial name
- Aut_Omic (NCT07427940)
- Testing
- Blood sample collection for ASD cells model production and Omic studies
- Where
- Italy
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta
Autism
The Relationship Between Sensory Profile and Ankle Muscle Shortness in Children With Autism
The aim of this study was to investigate the relationship between sensory profile and ankle muscle shortness in children with autism.
- Trial name
- NCT07159113
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 27 people
- Sponsor
- Abant Izzet Baysal University
Autism Spectrum Disorder, Autism
Effectiveness of a Developmental Reciprocity Treatment Program in Autism
This is a research study examining the effectiveness of a Developmental Reciprocity Treatment Program (DRT-P) in treating social deficits in children with Autism Spectrum Disorders (ASD).
- Trial name
- DRTP (NCT03131635)
- Testing
- Developmental Reciprocity Treatment Program (DRT-P)
- Where
- United States
- Volunteers
- 54 people
- Sponsor
- Stanford University
Autism in Children
Association Between Autism and Iron Deficiency
Association between Autism and Iron Deficiency in Children Diagnosed Autism
- Trial name
- NCT03601468
- Volunteers
- 50 people
- Sponsor
- Assiut University
Autism Spectrum Disorder
Smartphone-Based Neurobehavioral Assessments as a Diagnostic Aid in Autism
Retrospective case-control study to assess the diagnostic accuracy in autism spectrum disorder (ASD) of a new smartphone-based platform designed to conduct neurometric evaluations by measuring facial and behavioural reflexes.
- Trial name
- NCT06497218
- Testing
- Blinklab diagnostic device
- Where
- Morocco
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Blinklab Limited
Fragile X Syndrome
Trial of Sertraline to Treat Children With Fragile X Syndrome
This study is a control trial of sertraline (Zoloft) in fragile X syndrome children aged 2 years to 5 years 8 months old. The trial is six months long, and each participant will receive a series of tests at both the beginning and…
- Trial name
- NCT01474746
- Testing
- Sertraline
- Where
- United States
- Volunteers
- 57 people
- Sponsor
- Randi J. Hagerman, MD
Autism Spectrum Disorder
Targeting GABA-A for the Treatment of Social Disability in Young Adults With Autism Spectrum Disorders: A Phase II Proof of Mechanism Trial
This study is a NIMH-funded multi-site clinical trial that includes UCLA as the coordinating site, with Emory University and Seattle Children's Hospital, as other recruiting sites, and the Nathan Kline Institute as the Data…
- Trial name
- FAST-AS (NCT01966679)
- Testing
- AZD7325
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Autism Spectrum Disorder
A Deep Learning Algorithm Platform to Predict Autism Diagnosis and Subtypes
This is the first human study on ASD microbiome with robust methodologies: prospective and sibling designs, metagenomics profiles, establishing an ASD multi-dimensional databank (clinic, behavior, neurocognition, brain imaging…
- Trial name
- NCT04873674
- Testing
- ASD diagnosis, Psychiatric diagnosis
- Where
- Taiwan
- Volunteers
- 420 people
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorders
Examining the Efficacy of Mattress Technology in Improving the Sleep Quality of Children With ASD
The purpose of the present study is to evaluate the tolerability and efficacy of the Sound To Sleep System™ in improving the sleep quality of children with Autism Spectrum Disorder (ASD).
- Trial name
- NCT02739321
- Testing
- Sound to Sleep System
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- The Cleveland Clinic
Neuropsychiatric Disorder, Neurological Disorder
Studying Childhood-onset Behavioral, Psychiatric, and Developmental Disorders
Background: Many psychiatric, behavioral, and developmental disorders are genetic. This means that they tend to run in families. Some begin in childhood, while others do not appear until adulthood.
- Conditions
- Neuropsychiatric Disorder, Neurological Disorder, Neurodevelopmental Disorder, Sleep
- Trial name
- NCT01778504
- Where
- United States
- Volunteers
- 237 people
- Sponsor
- National Institute of Mental Health (NIMH)
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