Clinical trials: Pervasive Development Disorders
Autism Spectrum Disorder, Sleep Initiation and Maintenance Disorders
Sensory-Friendly Physical Activity for Sleep in Autistic Children
Sleep problems are very common in children on the autism spectrum and can worsen daytime behaviour, learning, and family stress. Many families have limited access to specialist sleep services.
- Trial name
- SFPAS (NCT07277101)
- Testing
- Sensory-Friendly Physical Activity Program (PAP), Conventional control group
- Where
- China
- Volunteers
- 106 people
- Sponsor
- Xili Wen
Autism Spectrum Disorder (ASD
Italian Validation of the Forensic Autism Risk Assessment Scale (FARAS-IT)
The study is a multicenter observational project designed to translate, culturally adapt, and validate the Italian version of the FARAS (FARAS-IT), a structured framework for assessing risk and protective factors specific to…
- Trial name
- ASD_FARASIT (NCT07374081)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- University of Bari
Autism Spectrum Disorder
Impact of Early Interventions on Neurocognitive Profile of Children With Autism Spectrum Disorder
The Early start Denver model (Rogers, 2010; Dawson, 2010) is a developmental and behavioral model that aim to enhance socio-comunicative abilities and also global development of children with Autism spectrum disorder (ASD).
- Trial name
- IDEAEYE (NCT03254264)
- Testing
- Early Start Denver Model, 'as-usual' intervention
- Where
- France
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Hôpital le Vinatier
Autism
A Study of Oxytocin in Children and Adolescents With Autistic Disorder
The investigators propose to conduct this pilot study to evaluate oxytocin as a supplemental treatment for improving social difficulties in individuals with autism.
- Trial name
- Oxytocin (NCT01308749)
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of North Carolina, Chapel Hill
Autism Spectrum Disorder, Autism
Examining the Effects of a Job Entry Intervention
The current study will examine the efficacy of a virtual reality (VR) intervention as well as a newly developed Kessler Foundation STRength IDentification and Expression tool (VR-STRIDE) with adolescents diagnosed with autism…
- Conditions
- Autism Spectrum Disorder, Autism, ASD
- Trial name
- IMPRESSIVE (NCT04771338)
- Testing
- VR-JIT/KF-STRIDE
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Kessler Foundation
Williams Beuren Syndrome, Autism Spectrum Disorder
Molecular Characterization of Patients Affected by Williams Syndrome and Autism.
Williams Beuren syndrome (WBS) is a multiple malformations/intellectual disability (ID) syndrome caused by 7q11.23 microdeletion and clinically characterized by a typical neurocognitive profile including excessive talkativeness…
- Trial name
- WBA (NCT04095585)
- Testing
- chromosomal microarray analysis (CMA) and whole exome sequencing (WES)
- Volunteers
- 6 people
- Sponsor
- Hospices Civils de Lyon
Autistic Spectrum Disorder, Anxiety Disorders
Feasibility Study of UP-A-AST Parent Group for Adolescents With Autism and Co-occurring Anxiety/Depression
Autism spectrum disorder (ASD) is associated with high rates of psychiatric comorbidity, particularly anxiety and depressive disorders, which contribute to significant impairment for affected youth and their families.
- Conditions
- Autistic Spectrum Disorder, Anxiety Disorders, Depressive Disorder
- Trial name
- NCT07637799
- Testing
- Unified Protocol-Adolescent Autism Parent Group (UP-A-AST)
- Where
- Sweden
- Volunteers
- 72 people
- Sponsor
- Sahlgrenska University Hospital
Autism Spectrum Disorder
Behavior Analytic Support of Needle-related Hospital Visits for Autistic Patients
The purpose of this study is to evaluate the effectiveness of the behavior analytic intervention in reducing the number of challenging behaviors exhibited by patients with Autism Spectrum Disorder (ASD) while increasing…
- Trial name
- NCT06712784
- Testing
- Treatment Package (for both simulation and procedure sessions
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Boston Medical Center
Autism Spectrum Disorder
The Effectiveness of Group Interpersonal Synchrony in Young Autistic Adults' Work Environment
Background: Few autistic adults are able to integrate successfully into the world of work given their difficulties adapting to the social and stressful aspects of work environments.
- Trial name
- NCT05846308
- Testing
- Structured synchronous physical training, Structured non-synchronous physical training
- Where
- Israel
- Volunteers
- 57 people
- Sponsor
- University of Haifa
Autism Spectrum Disorder
Participation-based Intervention on Community Participation and Parent Empowerment for Children With ASD
Community participation of children with ASD is affected by child (including body function and personal factors), family and environmental factors.
- Trial name
- PBI-ASD (NCT03721913)
- Testing
- participation-based intervention
- Where
- Taiwan
- Volunteers
- 24 people
- Sponsor
- Chang Gung University
Autism Spectrum Disorder, Obsessive-Compulsive Behavior
Cognitive Behavioural Therapy for Children With Autism Spectrum Disorder and Obsessive Compulsive Behaviour
Individuals with high functioning autism spectrum disorder (ASD) frequently experience obsessions and/or compulsions that are similar to those specified in Diagnostic and Statistical Manual of Mental Disorders (5th ed.; DSM-5)…
- Trial name
- NCT03123146
- Testing
- Functional Behavior-Based Cognitive Behavioral Therapy
- Where
- Canada
- Volunteers
- 37 people
- Sponsor
- Tricia Vause
Autism Spectrum Disorder
The Therapeutic Effect of TBS Stimulation on Emotion Regulation in Autism Spectrum Disorder
The investigator would like to investigate the impact of intermittent theta burst stimulation over left dorsolateral prefrontal cortex on emotion regulation in autism spectrum disorder
- Trial name
- NCT04987541
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder, Executive Functioning
Hybrid Effectiveness-Implementation Trial of an Executive Functioning Intervention for Children's Mental Health Services
This project aims to follow up on a prior project examining the impact of training therapists in an executive functioning intervention Unstuck and On Target (UOT) adapted for community mental health settings.
- Trial name
- NCT06651086
- Testing
- Unstuck and On Target, Unified Protocol for Children
- Where
- 2 sites in United States
- Volunteers
- 672 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Autism Spectrum Disorder
UCB Stem Cells for Autism Spectrum Disorders
Purpose. The goals of the study are to assess the safety of the intravenous infusion of umbilical cord blood (UCB) cells in patients with autism and to confirm changes in social/ communicative skills and cognitive functioning…
- Trial name
- NCT04710810
- Testing
- umbilical cord blood mononuclear stem cells
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- St. Petersburg Bekhterev Research Psychoneurological Institute
Schizophrenia, Autism Spectrum Disorder
Cerebellar Stimulation and Cognitive Control
The purpose of this study is to examine whether cerebellar stimulation can be used to improve cognitive deficits and mood in patients with schizophrenia, autism, bipolar disorder, Parkinson's disease, and major depression.
- Conditions
- Schizophrenia, Autism Spectrum Disorder, Bipolar Disorder, Depression
- Trial name
- NCT03217110
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS)
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Krystal Parker, PhD
Autism Spectrum Disorders, Anxiety
The Development of a Psychoeducational Tool to Manage Anxiety in People With Autism Spectrum Disorders
The purpose of this pilot intervention trial is to assess the efficacy of newly developed psychoeducation guides designed to manage anxiety in Autism Spectrum Disorder (ASD) by recruiting 30 participants with ASD and high levels…
- Trial name
- MANAGE (NCT02797379)
- Testing
- Psychoeducation
- Where
- 2 sites in United Kingdom
- Volunteers
- 35 people
- Sponsor
- King's College London
Autism, Intellectual Disabilities
Online Video Training for Teachers to Improve Reading Skills in Children Using Augmentative and Alternative Communication
The aim of this study is to investigate , via a randomized control trial (RCT), the effectiveness of an online video training platform designed for teachers to support the improvement of basic reading skills of children with…
- Trial name
- NCT06766188
- Testing
- Online Video training for Teachers based on Reading for all
- Where
- Norway
- Volunteers
- 70 people
- Sponsor
- Ostfold University College
Autism Spectrum Disorder, Asperger Disorder
Neurocircuitry of Autism- fMRI and Transcranial Magnetic Stimulation Studies
This study uses functional brain imaging and noninvasive brain stimulation techniques to study the brain basis of developmental disorders like Autism Spectrum Disorder and Asperger Disorder.
- Conditions
- Autism Spectrum Disorder, Asperger Disorder, Pervasive Developmental Disorder
- Trial name
- NCT01553240
- Testing
- TMS and functional MRI (Magstim)
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- New York State Psychiatric Institute
Autism Spectrum Disorder (ASD
Effects of Parent-child Co-participation in Physical Activity
Literature reviews and studies of physical activity (PA) interventions suggest that active parental involvement is an important component of supporting PA levels in children with autism spectrum disorders (ASD).
- Trial name
- NCT07236346
- Testing
- A parent-child co-participation in physical activity
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bayburt University
Autism Spectrum Disorder, Anxiety Disorders
DINO RCT - Treating Anxiety in Children With Autism
Anxiety is prevalent in young children, under 7 years of age, with autism. Yet, few studies have examined anxiety interventions for this age range, and only one anxiety treatment study has included young children with cognitive…
- Trial name
- NCT06066983
- Testing
- DINOSAUR, Psychoeducation
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
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