Clinical trials: Pervasive Development Disorders
Autism
Synthetic Human Secretin in Children With Autism
The purpose of the study is to determine whether multiple doses of secretin are safe and effective in the treatment of children with autism.
- Trial name
- NCT00036244
- Testing
- RG1068 (Synthetic Human Secretin)
- Where
- 15 sites in United States
- Sponsor
- Repligen Corporation
Autism Spectrum Disorder, Catatonia
Management of Catatonic Features in Adolescents With Profound Autism
The goal of this clinical trial is to learn if benzodiazepines and ECT can treat Catatonic features in Adolescents with Autistic spectrum disorder, it will also learn about Safety and efficacy of benzodiazepines and ECT.
- Trial name
- MOCFAPA (NCT07498387)
- Testing
- Intranasal Midazolam (Benzodiazepine Challenge Test), Oral Clonazepam, Electroconvulsive Therapy (ECT)
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Pervasive Child Development Disorders, Autism
Longitudinal and Biological Study of Childhood Disintegrative Disorder
OBJECTIVES: I. Compare the developmental course (language acquisition, diagnostic stability, predictors of outcome, and restricted interests and behaviors) of childhood disintegrative disorder versus autism and non-autistic…
- Trial name
- NCT00004458
- Where
- 2 sites in United States
- Volunteers
- 220 people
- Sponsor
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Adenovirus, Anesthesia
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
Understudied drugs will be administered to children per standard of care as prescribed by their treating caregiver and only biological sample collection during the time of drug administration will be involved.
- Conditions
- Adenovirus, Anesthesia, Anxiety, Anxiolysis
- Trial name
- PTN_POPS (NCT01431326)
- Testing
- The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care:
- Where
- 52 sites in United States, Canada and 3 more
- Volunteers
- 3,520 people
- Sponsor
- Daniel Benjamin
Autism Spectrum Disorder, Minimally Verbal Ability
Explore the Therapeutic Effect of Theta Burst Stimulation on Emotion Regulation in Autism With Minimally Verbal Ability or Intellectual Disability
The investigator would like to investigate the impact of theta-burst stimulation over left DLPFC in autism with minimally verbal ability or intellectual disability
- Conditions
- Autism Spectrum Disorder, Minimally Verbal Ability, Intellectual Disability
- Trial name
- NCT06974838
- Testing
- intermittent theta burst stimulation
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Chang Gung Memorial Hospital
Autism Spectrum Disorder
Psychometric Validation of the Camouflaging Autistic Traits Questionnaire
For many affected individuals, despite impairment and distress, autism spectrum disorder (ASD) is recognized and diagnosed late, in school age, adolescence, or even in adulthood, which could be due, among other things, to the use…
- Trial name
- CAT-Q/DE (NCT05989685)
- Where
- Germany
- Volunteers
- 622 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Autism Spectrum Disorder, Child
AI Toothbrush and Visual Pedagogy to Improve Oral Hygiene in Children With Autism Spectrum Disorder
This randomized clinical trial evaluates the effectiveness of an AI-enabled electric toothbrush and visual pedagogy materials in improving oral hygiene among children with autism spectrum disorder (ASD).
- Conditions
- Autism Spectrum Disorder, Child, Oral Health, Artificial Intelligence
- Trial name
- NCT07160517
- Testing
- Visual Pedagogy and Manual Toothbrushing
- Where
- Brazil
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Autism Spectrum Disorder
Validation of the French Adaptation of the RAADS-R Scale : Scale of Asperger Syndrome Diagnosis
The diagnosis of developmental disorders in adults is still difficult. Indeed, in France, there is not questionnaires to easily and accurately diagnose this disorder. Several diagnostic scales were developed in English.
- Trial name
- RAADS-R (NCT02826148)
- Testing
- RAADS-R scale
- Volunteers
- 324 people
- Sponsor
- University Hospital, Montpellier
Autism Spectrum Disorder, Oxytocin
Understanding Oxytocin's Neural and Behavioral Effects in Adolescents Diagnosed With Autism
The investigators explored the neural and behavioral effect of oxytocin on youth with Autism spectrum disorder using magnetoencephalography (MEG).
- Trial name
- NCT05096676
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Prof. Ilanit gordon
Cerebral Palsy, Autism
Rehabilitation of Children With Multiple Disabilities
The objective of the study is to compare the usual care and treatment of children and youth (0-19 years) with multiple developmental delays and disabilities and their families in Simcoe York with a co-ordinated, navigated…
- Conditions
- Cerebral Palsy, Autism, Down's Syndrome, Brain Injury
- Trial name
- NCT01379443
- Testing
- CTN model of care for children and their families
- Where
- Canada
- Volunteers
- 445 people
- Sponsor
- Children's Treatment Network
Autistic Disorder
An Exploratory, Double-Blind, Placebo-Controlled Study of the Medical Food Vayarin in Children With Autism Spectrum Disorder (ASD)
The primary study objective is to evaluate the efficacy of Vayarin_005 on ASD related symptoms in children.
- Trial name
- NCT02222285
- Testing
- Medical Food : Vayarin_005
- Where
- 2 sites in United States
- Volunteers
- 56 people
- Sponsor
- Enzymotec
Healthy Volunteer, Autistic Disorder, Asperger's Syndrome
A Non-Drug Study on the Relationship Between Exploratory Biomarkers and Functional Dimensions in Individuals With Autistic Disorder or Asperger's Syndrome
This multi-center, non-drug study will explore the relationship between exploratory biomarkers and functional dimensions in male adult individuals with Autistic Disorder or Asperger's Syndrome and healthy volunteer controls.
- Trial name
- NCT01669889
- Where
- 3 sites in United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hoffmann-La Roche
Bipolar Disorder, Schizophrenia
COMpassion for Psychiatric Disorders And Self-Stigma
People with mental disorders face frequent stigmatizing attitudes and behaviors from others . In response to this, they tend to isolate themselves, with the risk of impeding care and the process of recovery and integration into…
- Conditions
- Bipolar Disorder, Schizophrenia, Depression, Borderline Personality Disorder
- Trial name
- COMPASS (NCT05698589)
- Testing
- Compassion Focused Therapy, Ending Self Stigma
- Where
- 7 sites in France
- Volunteers
- 336 people
- Sponsor
- University Hospital, Strasbourg, France
Autism, Autism Spectrum Disorder
Work Chat: An Interactive Virtual Workday
Nearly 50,000 youth with autism spectrum disorder (ASD) transition from high school to adult life each year with only 25% of these transition-age youth with ASD (TAY-ASD) getting jobs within 2 years of graduation.
- Trial name
- NCT05565482
- Testing
- Work Chat: An Interactive Virtual Workday
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD)
Intensive Multimodal Neurorehabilitation Targeting Neuroplasticity in Pediatric Neurodevelopmental and Chromosomal Disorders
This observational study evaluates functional and developmental outcomes in pediatric participants undergoing a two week intensive multimodal neurorehabilitation program.
- Conditions
- Neurodevelopmental Disorders, Neurodevelopmental Disorders (NDD), Neurodevelopmental Disorders and Developmental Abnormalities, Developmental Delay (Disorder)
- Trial name
- GEN-HOPE (NCT07493096)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Healing Hope International
Autism Spectrum Disorder
The Impact of Group Based Activity Programmes on Children Who Have Autism and Their Families in Staffordshire
Participation in structured activities and physical activity (PA) have been linked to several indicators of positive development such as self-esteem and psychological health as well as greater academic outcomes and lower school…
- Trial name
- NCT04288986
- Testing
- Keep Achieving
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Midlands Psychology CIC
Preterm Birth, Preeclampsia
The ROOT Study: Scaling the 'Standard of Care Plus' Obstetric Nutrition Model to Optimize Maternal and Infant Health
The 'Standard of Care Plus' ('PLUS') model in the ROOT Study consists of analyzing select micronutrient and gene variants of pregnant females to construct trimester-specific and personalized nutrition and lifestyle…
- Conditions
- Preterm Birth, Preeclampsia, Gestational Diabetes Mellitus (GDM), Small for Gestational Age (SGA)
- Trial name
- ROOT (NCT07559773)
- Testing
- 'Standard of Care PLUS'
- Volunteers
- 500 people
- Sponsor
- GrowBaby Life Project
Autism Spectrum Disorder, Earthquake
The Effect of Parent Mediated Intervention Program on Children With ASD Exposed to Earthquake in Turkey in February 2023
After devastating natural events such as earthquakes, individuals with special needs experience much more difficulties. There is a limited number of studies investigating the impact of disasters on individuals with autism.
- Conditions
- Autism Spectrum Disorder, Earthquake, Behavior Problem of Childhood and Adolescence
- Trial name
- NCT05998382
- Testing
- Online group-based parent-mediated intervention program
- Where
- Turkey (Türkiye)
- Volunteers
- 57 people
- Sponsor
- Sabri Hergüner
Autistic Disorder, Asperger's Disorder
The Use of rTMS to Improve Theory of Mind Among Adults With Autism and Asperger's Disorder
Theory of mind (ToM) refers to the ability to infer others mental states. It includes a recognition that other individuals experience thoughts, feelings, intentions, and desires that may be different to our own.
- Trial name
- NCT00808782
- Testing
- Deep rTMS
- Where
- Australia
- Volunteers
- 30 people
- Sponsor
- Bayside Health
Feeding Disorder, Autism Spectrum Disorder
The Effect Of Occupational Therapy On Sensory-Based Feeding Problems
Feeding problems are common in individuals with Autism Spectrum Disorder (ASD).This study was planned to investigate the effect of occupational theraphy on sensory feeding problems in ASD.
- Conditions
- Feeding Disorder, Autism Spectrum Disorder, Sensory Integration Disorder (Disorder)
- Trial name
- NCT03820869
- Testing
- Family Training, Occupational Therapy
- Volunteers
- 18 people
- Sponsor
- Hacettepe University
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