Clinical trials: Peyronie Disease
Peyronie's Disease
Peyronie's Disease Treatment Protocol
Treatment of Peyronie's disease remains difficult. The purpose of this study is to test the safety and efficacy of a new compound to treat this disease.
- Trial name
- NCT02072018
- Testing
- H-100
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Hybrid Medical
Peyronie Disease
Low-Intensity Extracorporeal Shockwave Therapy and Vacuum Erectile Device as a Treatment for Peyronies Disease.
Aim The primary aim is to examine whether LI-ESWT and vacuum erectile device (VED) followed by manipulation exercises has beneficial effect on PD patients compared to a placebo group.
- Trial name
- NCT03530540
- Testing
- low-intensity extracorporeal shockwave therapy, Penile pump
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Peyronie Disease
French Translation and Validation of the PEYronie's Disease QUESTionnaire
This study is a prospective cohort dedicated to peyronie's disease. The aim is to validate the french translation of the peyronie's disease questionnaire. The primary endpoint is the response rate to the questionnaire.
- Trial name
- FRAPEYQUEST (NCT05768867)
- Testing
- FRAnçaise du PEYronie's Disease QUESTionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse
Peyronie Disease
Pelvic CT with Agatston Calcium Score for Peyronie Disease
The purpose of this study is to find out how including a CT exam of the penis can help urologists make treatment decisions for patients with calcified Peyronie's disease.
- Trial name
- NCT05480683
- Testing
- CT exam
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Penile Induration, Penile Diseases
Stem Cell Treatment of Peyronie´s Disease.
Purpose of the project is to investigate if a single injection of autologous stromal vascular fraction into and around plaque is a safe and suitable treatment.
- Trial name
- NCT04771442
- Testing
- Stromal vascular fraction
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Peyronie's Disease
Pharmacokinetics of a Single Treatment Cycle of AA4500 0.58 mg in Men With Peyronie's Disease
This study is a Phase 2, open-label study to assess the pharmacokinetics (PK) and safety of AA4500 0.58 mg in men with Peyronie's disease.
- Trial name
- NCT01430169
- Testing
- AA4500
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease (PD)
Xiaflex® Plus Testosterone Treatment Pilot Study Protocol
In this open-label, six-month, pilot study of men with Peyronie's disease there will be one subject group consisting of 20 subjects. All subjects will receive Xiaflex® plus testosterone (T) treatment (Aveed®).
- Trial name
- NCT03815331
- Testing
- Xiaflex®, Aveed
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Men's Health Boston
Peyronie Disease
Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease
Our team has previously demonstrated efficacy in performing a novel collagenase Clostridium histolyticum (CCH) injection protocol in men who previously failed to achieve a response to an initial 4 series of CCH.
- Trial name
- NCT06649539
- Testing
- Collagenase Clostridium Histolyticum, RestoreX, Sildenafil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Erectile Dysfunction, Peyronie' Disease
Management of Peyronie's Disease With Adipose Tissue Stem Cell
Erectile dysfunction is growing in prevalence all over the world and one of the most existing disease in old age patients There is many lines of treatment concerning the status of patient like psychosexual, medical, and surgical…
- Trial name
- NCT02414308
- Testing
- Adipose tissue stem cell injection
- Where
- 2 sites in Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Man Clinic for Andrology, Male Infertility and Sexual Dysfunction
Peyronie Disease, Sexual Dysfunction, Physiological
PRP for Treatment of Peyronie's Disease
The purpose of this study is to learn about the effects of Platelet-Rich Plasma (PRP) injection in men with Peyronie's Disease (PyD).
- Conditions
- Peyronie Disease, Sexual Dysfunction, Physiological, Sexual Dysfunction Male, Genital Diseases, Male
- Trial name
- NCT04512287
- Testing
- Autologous Platelet-Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Miami
Peyronie Disease, Penile Diseases
Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease
Investigation of the effect of Low-intensity extracorporeal shockwave therapy (ESWT) for Peyronie's disease (PD) via a single blind, sham-controlled, randomized clinical trial.
- Trial name
- ONDELA (NCT04821115)
- Testing
- Low intensity choc waves therapy (active applicator)
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Hopital Foch
Peyronie's Disease
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of PD
Prospective, open labeled, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of…
- Trial name
- PMD-MSC-PD-01 (NCT02395029)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Melissa Marchand
Peyronie Disease
Treatment Response to Xiaflex for Men With Peyronie's Disease
The purpose of this research study is to develop a database of patients with Peyronie's disease who are treated at the University of Miami.
- Trial name
- NCT03774264
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Peyronie's Disease
Microneedle Treatment of Chronic Phase Peyronie's Disease: A Pilot Clinical Trial
Peyronie's Disease (PD) is a disorder of the penis where scar tissue (composed of excessive and disorganized collagen) known as a "plaque," forms along the shaft of the penis.
- Trial name
- NCT07128420
- Testing
- Application of 3 sessions of microneedle therapy
- Where
- Canada
- Volunteers
- 10 people
- Sponsor
- Ottawa Hospital Research Institute
Peyronie Disease
Peyronie Disease Questionnaire (PDQ): Turkish Validation
The purpose of the present study is to translate into the Turkish and a perform a validation of the Turkish version of a PDQ and to ensure the use of Turkish validation of the PDQ in clinical use and studies.
- Trial name
- Turkish PDQ (NCT06621420)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Acibadem University
Peyronie's Disease
Study of AA4500 in the Treatment of Peyronie's Disease
This study is a Phase 3, double-blind, randomized, placebo-controlled study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Approximately 400 (267 AA4500 and 133 placebo) men will be randomized.
- Trial name
- NCT01221597
- Testing
- AA4500
- Where
- 34 sites in United States, Australia
- Volunteers
- 418 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
H-22411: BOTOX® for Peyronie's Disease
Peyronie's disease is a condition in which a plaque, or hard lump, forms on the penis. It causes hardened tissue, pain, and an abnormal bending in the penis. These symptoms are more severe during an erection.
- Trial name
- NCT00812838
- Testing
- 100 units of Botulinum Toxin Type A, Preservative free normal saline, 100 units Botulinum Toxin A
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mohit Khera
Peyronie's Disease
A Study of AA4500 in Men With Peyronie's Disease
This study is a Phase 3, open-label study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Subjects will be screened for study eligibility within 21 days before the initial injection of study drug…
- Trial name
- NCT01243411
- Testing
- AA4500
- Where
- 39 sites in United States, Denmark and 7 more
- Volunteers
- 348 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Erectile Dysfunction, Peyronie's Disease
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis
This trial will study the safety and efficacy of intravenous and intracavernosal or interstitial delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Peyronie's disease…
- Conditions
- Erectile Dysfunction, Peyronie's Disease, Interstitial Cystitis
- Trial name
- NCT05147779
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Complication of Surgical Procedure
Outcomes of Surgical Correction of Penile Curvature in Adult
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous…
- Trial name
- NCT03313986
- Volunteers
- 50 people
- Sponsor
- Assiut University