Clinical trials: Peyronie Disease
Peyronie Disease, Penile Curvature
Platelet-Rich Plasma Injections From Cord Blood + Penile Traction vs. Penile Traction Alone in Patients With Peyronie's Disease. Open-label, Single-center Randomized Study
The goal of this clinical trial is to learn if Platelet-Rich Plasma Injections from Cord Blood (CB-PRP) is useful in Peyronie disease.
- Conditions
- Peyronie Disease, Penile Curvature, PRP Injection, Cord Blood
- Trial name
- CB-PRP-TRAC1 (NCT07010900)
- Testing
- Injection
- Where
- Italy
- Volunteers
- 42 people
- Sponsor
- Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Peyronie Disease
Medical Treatment of Peyronie's Disease With Collagenase Clostridium Histolyticum
Peyronie's disease is the appearance of a fibrosis plaque on the albuginea of the corpora cavernosa, which produces mechanical traction at the time of erection, inducing a deformation/curvature of the erect penis.
- Trial name
- NCT04370652
- Where
- France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Peyronie's Disease
The Safety and Effectiveness of AA4500 in Subjects With Peyronie's Disease
This study evaluated the safety and effectiveness of AA4500 in improving the impact of Peyronie's disease on quality of life and improving penile curvature in men with Peyronie's disease
- Trial name
- NCT00755222
- Testing
- AA4500
- Where
- 12 sites in United States
- Volunteers
- 147 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
Long-term Safety, Curvature Deformity Characterization, and Immunogenicity Over Time in Subjects Previously Treated With AA4500 for Peyronies Disease
This a Phase 4 non-treatment, long-term follow-up study of subjects who received AA4500 in a 12-month double blind placebo-controlled study (AUX CC 803 or AUX-CC-804) or in a 9-month open label study (AUX-CC-802 or AUX-CC-806)…
- Trial name
- NCT02298829
- Testing
- Subjects Previously Treated with AA4500
- Where
- 30 sites in United States
- Volunteers
- 184 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie Disease
Pilot Study on the Efficacy and Safety of FIBRORESTIL® as an Adjuvant Intralesional Treatment in Patients With Peyronie's Disease Receiving Standard Therapy
Peyronie's disease is a connective tissue disorder of the penis characterized by the formation of fibrous plaques in the tunica albuginea, leading to penile curvature, possible erectile dysfunction, and significant physical and…
- Trial name
- FIBRONIE (NCT07341529)
- Testing
- Intralesional hyaluronic acid-based enzymatic medical device, Standard conservative treatment for Peyronie's disease
- Where
- 2 sites in Spain
- Volunteers
- 38 people
- Sponsor
- Lyx Institute
Peyronie's Disease
Investigation of Surgery, Collagenase, and Restorex for the Improvement of Peyronie's
The purpose of this study is to compare key clinical outcomes of collagenase clostridium histolyticum injections versus surgery for the management of Peyronie's Disease.
- Trial name
- iSCRIP (NCT04786106)
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex] (CCH), Penile Plication Surgery, Incision and Grafting (I&G) Surgery
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Peyronie's Disease
Study of AA4500 in the Treatment of Peyronie's Disease
This study is a Phase 3, double-blind, randomized, placebo-controlled study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Approximately 300 (200 AA4500 and 100 placebo) men will be randomized.
- Trial name
- NCT01221623
- Testing
- AA4500
- Where
- 34 sites in United States, Australia
- Volunteers
- 418 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company