Clinical trials: Peyronies Disease
Complication of Surgical Procedure
Outcomes of Surgical Correction of Penile Curvature in Adult
Penile curvature in adults is divided into two main categories the first is congenital penile curvature with orthotopic meatus and the other is acquired curvature which its common causes are Peyronie's disease (PD) and previous…
- Trial name
- NCT03313986
- Volunteers
- 50 people
- Sponsor
- Assiut University
Peyronie's Disease
H-22411: BOTOX® for Peyronie's Disease
Peyronie's disease is a condition in which a plaque, or hard lump, forms on the penis. It causes hardened tissue, pain, and an abnormal bending in the penis. These symptoms are more severe during an erection.
- Trial name
- NCT00812838
- Testing
- 100 units of Botulinum Toxin Type A, Preservative free normal saline, 100 units Botulinum Toxin A
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mohit Khera
Peyronie Disease
Novel Nanofat Regenerative Surgical Technique for Peyronies' Disease Treatment
Peyronies' disease (PD) is an acquired connective tissue disorder characterized with the growth of fibrous and/or calcified plaques in the tunica albuginea of the penis.
- Trial name
- IPPNANOFAT (NCT05316714)
- Testing
- Nanofat grafing
- Where
- Italy
- Volunteers
- 35 people
- Sponsor
- University of Roma La Sapienza
Peyronie Disease, Penile Diseases
Safety and Efficacy of Low-intensity Shockwave Therapy for Peyronie's Disease
Investigation of the effect of Low-intensity extracorporeal shockwave therapy (ESWT) for Peyronie's disease (PD) via a single blind, sham-controlled, randomized clinical trial.
- Trial name
- ONDELA (NCT04821115)
- Testing
- Low intensity choc waves therapy (active applicator)
- Where
- 4 sites in France
- Volunteers
- 120 people
- Sponsor
- Hopital Foch
Peyronie's Disease
A Study of AA4500 in Men With Peyronie's Disease
This study is a Phase 3, open-label study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Subjects will be screened for study eligibility within 21 days before the initial injection of study drug…
- Trial name
- NCT01243411
- Testing
- AA4500
- Where
- 39 sites in United States, Denmark and 7 more
- Volunteers
- 348 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
Assessment of the Value of FAPI and FDG-PET-CT in Diagnosis of Acute Phase Peyronie's Disease
The goal of this clinical trial is to learn if FAPI-PET/CT and/or FDG-PET/CT scan is able to detect active fibroblast tissue and inflammation in patients with acute or chronic phase PD.
- Trial name
- Hippocrates (NCT07903987)
- Testing
- 68Ga-FAPI (gallium-68-labeled fibroblast activation protein inhibitor)
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Peyronie Disease
Medical Treatment of Peyronie's Disease With Collagenase Clostridium Histolyticum
Peyronie's disease is the appearance of a fibrosis plaque on the albuginea of the corpora cavernosa, which produces mechanical traction at the time of erection, inducing a deformation/curvature of the erect penis.
- Trial name
- NCT04370652
- Where
- France
- Volunteers
- 156 people
- Sponsor
- University Hospital, Montpellier
Peyronies Disease
Fractionated Carbon Dioxide Laser Therapy for Treatment of Peyronie's Disease
This is a pilot study that evaluates the use of Fractional Carbon Dioxide Laser Therapy in the treatment of Peyronie's Disease. Study participants will be assigned to receive Fractional Carbon Dioxide Laser Therapy at 10-15%…
- Trial name
- NCT04326465
- Testing
- Fractional Carbon Dioxide Laser Therapy at 10-15% Laser Density Coverage
- Where
- Canada
- Volunteers
- 5 people
- Sponsor
- University of British Columbia
Peyronie Disease
Treatment Response to Xiaflex for Men With Peyronie's Disease
The purpose of this research study is to develop a database of patients with Peyronie's disease who are treated at the University of Miami.
- Trial name
- NCT03774264
- Where
- United States
- Volunteers
- 80 people
- Sponsor
- University of Miami
Peyronie Disease, Penile Curvature
Focused Shock Wave Therapy Outcomes in Peyronie's Disease and Erectile Dysfunction
The purpose of this research is to determine the pure or additional effects of penile shockwave therapy with low intensity linear shock wave machine for penile curvature (and/or erectile dysfunction) vs patients' undergoing other…
- Conditions
- Peyronie Disease, Penile Curvature, Erectile Dysfunction
- Trial name
- NCT05646602
- Testing
- Collagenase Clostridium Histolyticum, Duolith SD1 T-TOP
- Where
- United States
- Sponsor
- Mayo Clinic
Peyronie Disease
Extracorporeal Shockwave Therapy in the Treatment of Peyronie's Disease
Investigation of the effectiveness of extracorporeal shock wave therapy in the treatment of Peyronie's disease.
- Trial name
- NCT07317297
- Testing
- Extracorporeal Shockwave Therapy, control
- Where
- Azerbaijan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Peyronie Disease
Pelvic CT with Agatston Calcium Score for Peyronie Disease
The purpose of this study is to find out how including a CT exam of the penis can help urologists make treatment decisions for patients with calcified Peyronie's disease.
- Trial name
- NCT05480683
- Testing
- CT exam
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Peyronie's Disease
Pharmacokinetics of a Single Treatment Cycle of AA4500 0.58 mg in Men With Peyronie's Disease
This study is a Phase 2, open-label study to assess the pharmacokinetics (PK) and safety of AA4500 0.58 mg in men with Peyronie's disease.
- Trial name
- NCT01430169
- Testing
- AA4500
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
A Phase 3, Open-label Study of the Safety and Effectiveness of AA4500 Administered Twice Per Treatment Cycle for up to Four Treatment Cycles (2 x 4) in Men With Peyronie's Disease
This study is a Phase 3, open-label study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Subjects will be screened for study eligibility within 21 days before the initial injection of study drug…
- Trial name
- NCT01685437
- Testing
- AA4500
- Volunteers
- 189 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie Disease
Delayed Dose Collagenase Clostridium Histolyticum (CCH) Protocol for Men With Peyronie's Disease
Our team has previously demonstrated efficacy in performing a novel collagenase Clostridium histolyticum (CCH) injection protocol in men who previously failed to achieve a response to an initial 4 series of CCH.
- Trial name
- NCT06649539
- Testing
- Collagenase Clostridium Histolyticum, RestoreX, Sildenafil
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Charitable Union for the Research and Education of Peyronie's Disease
Peyronie's Disease
Additional Xiaflex® Treatment in Patients With Peyronie's Disease Recurrence, Worsening, or Incomplete Response
Subjects who have had an incomplete response to previous Xiaflex® will receive up to 4 additional cycles of treatment.
- Trial name
- NCT03767452
- Testing
- Xiaflex® 0.58 mg
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Manhattan Medical Research Practice, PLLC
Penile Induration, Penile Diseases
Stem Cell Treatment of Peyronie´s Disease.
Purpose of the project is to investigate if a single injection of autologous stromal vascular fraction into and around plaque is a safe and suitable treatment.
- Trial name
- NCT04771442
- Testing
- Stromal vascular fraction
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Peyronie Disease, Sexual Dysfunction, Physiological
PRP for Treatment of Peyronie's Disease
The purpose of this study is to learn about the effects of Platelet-Rich Plasma (PRP) injection in men with Peyronie's Disease (PyD).
- Conditions
- Peyronie Disease, Sexual Dysfunction, Physiological, Sexual Dysfunction Male, Genital Diseases, Male
- Trial name
- NCT04512287
- Testing
- Autologous Platelet-Rich Plasma (PRP)
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- University of Miami
Peyronies Disease
Title Fractioned CO2 Laser in the Treatment of Chronic Phase Peyronie's Disease
Peyronie's Disease (PD) is a fibrosing disorder of the penis where scar tissue (composed of excessive and disorganized collagen) known as a "plaque," forms along the shaft of the penis.
- Trial name
- NCT07177833
- Testing
- Fractional CO2 laser
- Where
- Canada
- Volunteers
- 60 people
- Sponsor
- Ottawa Hospital Research Institute
Peyronie Disease
French Translation and Validation of the PEYronie's Disease QUESTionnaire
This study is a prospective cohort dedicated to peyronie's disease. The aim is to validate the french translation of the peyronie's disease questionnaire. The primary endpoint is the response rate to the questionnaire.
- Trial name
- FRAPEYQUEST (NCT05768867)
- Testing
- FRAnçaise du PEYronie's Disease QUESTionnaire
- Where
- France
- Volunteers
- 30 people
- Sponsor
- University Hospital, Toulouse