Clinical trials: Peyronies Disease
Peyronie's Disease (PD)
Xiaflex® Plus Testosterone Treatment Pilot Study Protocol
In this open-label, six-month, pilot study of men with Peyronie's disease there will be one subject group consisting of 20 subjects. All subjects will receive Xiaflex® plus testosterone (T) treatment (Aveed®).
- Trial name
- NCT03815331
- Testing
- Xiaflex®, Aveed
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Men's Health Boston
Erectile Dysfunction, Peyronie's Disease
Safety of Cultured Allogeneic Adult Umbilical Cord Stem Cells for Peyronie's Disease, ED, and Interstitial Cystitis
This trial will study the safety and efficacy of intravenous and intracavernosal or interstitial delivery of cultured allogeneic adult umbilical cord derived mesenchymal stem cells for the treatment of Peyronie's disease…
- Conditions
- Erectile Dysfunction, Peyronie's Disease, Interstitial Cystitis
- Trial name
- NCT05147779
- Testing
- AlloRx
- Where
- Antigua and Barbuda
- Volunteers
- 20 people
- Sponsor
- The Foundation for Orthopaedics and Regenerative Medicine
Peyronie Disease
Safety and Efficacy of Intralesional HiLow Hyaluronic Acid in the Treatment of Peyronie's Disease (PD)
Prospective, open-label, single-arm, multicentric, pilot clinical study to confirm the safety of HiLow hyaluronic acid sodium salt for intralesional penile injection in patients affected by PD.
- Trial name
- NCT05871177
- Testing
- Pre-filled syringe of HiLow Hyaluronic Acid Sodium Salt
- Where
- 3 sites in Italy
- Volunteers
- 40 people
- Sponsor
- IBSA Farmaceutici Italia Srl
Peyronie Disease, Erectile Dysfunction
Concurrent Low Intensity Shockwave Therapy on Collagenase Clostridium Histolyticum for Peyronie's Disease
The purpose of this research is to determine whether or not low-intensity shockwave therapy (LiSWT) with Xiaflex treatment will result in greater improvements to the curvature of the penis.
- Trial name
- NCT06065436
- Testing
- Collagenase Clostridium Histolyticum, Storz Duolith LiSWT
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Mayo Clinic
Peyronie's Disease
Long-term Safety, Curvature Deformity Characterization, and Immunogenicity Over Time in Subjects Previously Treated With AA4500 for Peyronies Disease
This a Phase 4 non-treatment, long-term follow-up study of subjects who received AA4500 in a 12-month double blind placebo-controlled study (AUX CC 803 or AUX-CC-804) or in a 9-month open label study (AUX-CC-802 or AUX-CC-806)…
- Trial name
- NCT02298829
- Testing
- Subjects Previously Treated with AA4500
- Where
- 30 sites in United States
- Volunteers
- 184 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Peyronie's Disease
Evaluate the Safety and Feasibility of Injecting PMD-MSC Into the Penis to Treat the Symptoms of PD
Prospective, open labeled, non-randomized, study to be conducted at a single center. Ten subjects will undergo an injection of Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs) into the penis for the treatment of…
- Trial name
- PMD-MSC-PD-01 (NCT02395029)
- Testing
- Placental Matrix-Derived Mesenchymal Stem Cells (PMD-MSCs)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Melissa Marchand
Peyronie's Disease (PD)
Comparative Outcomes of Subtunical Microdissection and Grafting Versus Classical Plaque Incision and Grafting in Complex Peyronie's Disease
The goal of this clinical study is to compare two surgical techniques used for the treatment of complex Peyronie's disease. Peyronie's disease can cause penile curvature, deformity, and difficulties during sexual intercourse due…
- Trial name
- Peyronie (NCT07470528)
- Testing
- Subtunical microdissection and grafting, Classic plaque Incision and Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Namik Kemal University
Peyronie Disease
Low-Intensity Extracorporeal Shockwave Therapy and Vacuum Erectile Device as a Treatment for Peyronies Disease.
Aim The primary aim is to examine whether LI-ESWT and vacuum erectile device (VED) followed by manipulation exercises has beneficial effect on PD patients compared to a placebo group.
- Trial name
- NCT03530540
- Testing
- low-intensity extracorporeal shockwave therapy, Penile pump
- Where
- Denmark
- Volunteers
- 50 people
- Sponsor
- Odense University Hospital
Peyronie's Disease
Study of AA4500 in the Treatment of Peyronie's Disease
This study is a Phase 3, double-blind, randomized, placebo-controlled study of the safety and efficacy of AA4500 0.58 mg in subjects with Peyronie's disease. Approximately 300 (200 AA4500 and 100 placebo) men will be randomized.
- Trial name
- NCT01221623
- Testing
- AA4500
- Where
- 34 sites in United States, Australia
- Volunteers
- 418 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company