Clinical trials: Phacoemulsification, open to volunteers
Cataract Extraction
PRO-232 in Patients Subjected to Cataract Surgery
The main objective of this study is to evaluate the efficacy and safety of the PRO-232 formulation manufactured by Laboratorios Sophia S.A. de C.V.
- Trial name
- PRO-232 (NCT07305987)
- Testing
- Moxifloxacin / Dexamethasone Ophthalmic Solution, Moxifloxacin Hydrochloride, Ophthalmic, Dexamethasone phosphate
- Where
- 2 sites in Mexico
- Volunteers
- 134 people
- Sponsor
- Laboratorios Sophia S.A de C.V.
Non-Center, Diabetic Macular Edema
Non-Center Involving Diabetic Macular Edema Progression in Early Postoperative Period After Phacoemulsification
This study aims to evaluate the progression of non-center-involving diabetic macular edema in the early postoperative period following phacoemulsification.
- Conditions
- Non-Center, Diabetic Macular Edema, Phacoemulsification
- Trial name
- NCT07038967
- Testing
- Coloured photography, Fluorescein angiography, Optical coherence tomography
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Ain Shams University
Diabetic Retinopathy (DR), Diabetic Macular Edema (DME)
Comparing Single Versus Multiple Anti-VEGF Injections in Diabetic Patients Undergoing Cataract Surgery
Objective of this randomised controlled trial is to compare the efficacy of a single per operative anti VEGF injection with repeated postoperative anti VEGF injections in the prevention of diabetic retinopathy progression after…
- Conditions
- Diabetic Retinopathy (DR), Diabetic Macular Edema (DME), Cataract, Phacoemulfisication+IOL Implantation
- Trial name
- NCT07301775
- Testing
- Aflibercept (Eylea)
- Where
- 2 sites in Pakistan
- Volunteers
- 166 people
- Sponsor
- Ahmad Zeeshan Jamil
Ultrasound Biomicroscopy, Intraocular Lens
Ultrasound Biomicroscopic Assessment of Intraocular Lens Tilt and Decenteration After Phacoemulsification
This study aims to assess intraocular lens (IOL) tilt and decenteration by means of ultrasound biomicroscopy after phacoemulsification.
- Conditions
- Ultrasound Biomicroscopy, Intraocular Lens, Tilt, Decenteration
- Trial name
- NCT07769944
- Testing
- Ultrasound biomicroscopy
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University
Cataract Bilateral
"Comparative Study of High-frequency Pulsed Vacuum Technology Versus Phacoemulsification for Cataract Surgery
Cataracts are cloudings of the lens, primarily due to aging. Surgery is the primary treatment for cataracts. The most commonly used surgical technique is phacoemulsification, which involves fragmenting the lens using a…
- Trial name
- PULSEM (NCT07074431)
- Testing
- Eye 1 by the Technique by high-frequency pulsed vacuum technology, Eye 2 : Surgery byTechnique by high-frequency pulsed vacuum technology
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Clinique Victor Pauchet
Cataract, Binaural Beats
Binaural Sound During Phacoemulsification and Posterior Chamber Lens Implantation in Geriatric Patients
The purpose of this study is to evaluate the effects of binaural beats on patient satisfaction and intraoperative comfort in patients aged 65 years or older undergoing cataract surgery (phacoemulsification and posterior chamber…
- Conditions
- Cataract, Binaural Beats, Geriatric Anesthesia
- Trial name
- NCT07609186
- Testing
- binaural beats
- Where
- South Korea
- Volunteers
- 60 people
- Sponsor
- Seoul National University Hospital
Cataract, Endothelial Cell Density
Trial Comparing miLOOP Device Assisted Phacoemulsification vs Standard Surgery for Dense Cataracts: Effects on Endothelial Cell Loss, Energy Use, and Vision Recovery
The goal of this clinical trial is to find out if using the miLOOP device during cataract surgery confers additional protection against cornea (endothelial) cells loss by reducing the amount of ultrasound energy needed.
- Conditions
- Cataract, Endothelial Cell Density, Cumulative Dispersive Energy
- Trial name
- NCT07898007
- Testing
- The miLOOP utilizes a nickel-titanium (nitinol) loop to ensnare and exert centripetal cutting forces on the lens nucleus with decreasing loop diameter, Conventional phacoemulsification cataract surgery
- Where
- Malaysia
- Volunteers
- 68 people
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Neovascular (wet) Age-Related Macular Degeneration
The Effect of Phacoemulsification on the Macular Changes in Patients with Neovascular Age-related Macular Degeneration
The macula has a very high concentration of photoreceptor cells - the cells that detect light. They send signals to the brain, which interprets them as images.
- Trial name
- it does not (NCT06759597)
- Volunteers
- 50 people
- Sponsor
- Assiut University
Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma
Combined Phacoemulsification-Goniotomy in Primary Open-Angle and Primary Angle-Closure Glaucoma
This study evaluates whether combining cataract surgery (phacoemulsification) with incisional goniotomy effectively lowers intraocular pressure (IOP) and reduces the need for glaucoma medications in patients with coexisting…
- Conditions
- Primary Open-Angle Glaucoma, Primary Angle-Closure Glaucoma, Cataract
- Trial name
- NCT07821827
- Testing
- Combined Phacoemulsification and Goniotomy
- Volunteers
- 70 people
- Sponsor
- Assiut University
Postoperative Ocular Inflammation, Postoperative Ocular Pain
A Phase 3 Study Evaluating the Safety and Efficacy of TRIESENCE® (Injectable Suspension) for the Treatment of Ocular Inflammation and Pain After Ophthalmic Surgery
This study is designed to evaluate the safety and efficacy of TRIESENCE® (triamcinolone acetonide injectable suspension) in patients undergoing ophthalmic procedures.
- Trial name
- NCT07832552
- Testing
- TRIESENCE (triamcinolone acetonide injectable suspension)
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Harrow Inc
Age-related Cataract
The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors
The goal of this observational study is to evaluate the location of phacoemulsification tip measured by intraoperative OCT during cataract surgeries and its impact on early postoperative changes of cornea and visual acuity.
- Trial name
- NCT07550907
- Testing
- cataract surgery
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Cataract
Comparison of Early Postoperative Visual Acuity Between Intracapsular and Supracapsular Phacoemulsification: A Randomized Controlled Clinical Trial
Cataracts are the leading cause of blindness worldwide, and phacoemulsification combined with intraocular lens implantation has become the most mainstream surgical approach.
- Trial name
- NCT07407049
- Testing
- Supracapsular Phacoemulsification, Intracapsular Phacoemulsification
- Where
- China
- Volunteers
- 128 people
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Astigmatism, Phacoemulsification
Effectiveness and Safety of Limbal Relaxing Incisions for Correcting Post Phacoemulsification High Astigmatism
To compare the effect of Limbal relaxing incisions (LRIs) plus spectacle correction versus spectacle correction alone on subjective and objective improvement in visual function for correcting post phacoemulsification high…
- Trial name
- NCT06896357
- Testing
- Limbal relaxing incisions
- Volunteers
- 30 people
- Sponsor
- Assiut University
Endothelial Cell Loss, Corneal, Cataract and Intraocular Lens (IOL) Surgery
Effect of Vitamin C Supplementation in Corneal Endothelial Damage in Phacoemulsification of Patients with Hard Cataracts
The goal of this clinical trial is to analyze the protective effects of oral ascorbic acid on the corneal endothelial layer undergoing oxidative stress due to phacoemulsification in patients with hard cataracts.
- Trial name
- NCT06781970
- Testing
- Oral Vitamin C
- Where
- 2 sites in Indonesia
- Volunteers
- 120 people
- Sponsor
- Universitas Indonesia
Primary Open-angle Glaucoma, Cataract
MINIject Implantation Combined With Cataract Surgery in Patients With POAG and Cataract
The study will assess safety and performance of MINIject implant in patients with open-angle glaucoma uncontrolled by topical hypotensive medications in conjunction with cataract surgery.
- Trial name
- STAR-VI (NCT05432245)
- Testing
- Phacoemulsification combined with minimally invasive glaucoma surgery (MIGS)
- Where
- 4 sites in Panama, Spain and 1 more
- Volunteers
- 30 people
- Sponsor
- iSTAR Medical
Glaucoma
Alcon Hydrus Stent Implantation - Long Term Follow up After 8 Years
The purpose of this study is to evaluate the long-term effectiveness and safety of the Hydrus implant combined with concomitant phacoemulsification for lowering intraocular pressure (IOP).Glaucoma patients often have high…
- Trial name
- NCT07460791
- Where
- Germany
- Volunteers
- 200 people
- Sponsor
- Johannes Gutenberg University Mainz
Cataract
Unity VCS: A Comparison Study Evaluating Corneal Clarity and Thickness
Phacoemulsification (cataract surgery) is usually performed while temporarily increasing the pressure inside the eye. The purpose of this study is to see if maintaining different pressure levels inside the eye during this…
- Trial name
- NCT07222150
- Testing
- Cataract surgery with Unity VCS, Cataract surgery with Centurion with Ozil
- Where
- United States
- Volunteers
- 105 people
- Sponsor
- Metrolina Eye Associates, PLLC
Dry Eye Disease (DED), Cataract (Post-operative Cataract Surgery Follow-up)
Effect of Dry Eye Disease on Accuracy of Intraocular Lens Power Calculation Before Phacoemulsification
This study aims to determine the effect of dry eye disease on intraocular lens power calculation and the postoperative refractive outcome.
- Trial name
- NCT07525336
- Testing
- dry eye disease optimization
- Volunteers
- 100 people
- Sponsor
- Assiut University
Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery
This Clinical Trial Compares Two Phacoemulsification Systems Used in a Bilateral Cataract Surgery Subjects in Order to Study CDE and Ultrasound Time During Cataract Removal
This clinical trial compares two phacoemulsification systems used in a bilateral cataract surgery subjects, in order to study CDE and Ultrasound time during cataract removal
- Conditions
- Nuclear Sclerosis of the Lens, Phacoemulsification Cataract Surgery, Cataract Bilateral
- Trial name
- CDE (NCT07468877)
- Testing
- Cataract extraction with phacoemulsification comparing two systems
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Nicole Fram M.D.
Cataract
Effective Phaco Time and Endothelial Cell Loss When Using Veritas
This study is a single center, prospective study of cumulative dissipated energy and endothelial cells loss per phacoemulsification procedure after successful cataract surgery.
- Trial name
- NCT07176416
- Testing
- Veritas Vision System
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Aloha Vision Consultants