Clinical trials: Pharmaceutical Care
Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome)
RECOMMEND Platform Trial
The goal of this platform trial is to determine the efficacy, safety and cost-effectiveness of various interventions in patients with acute cardiorespiratory failure requiring extracorporeal membrane oxygenation (ECMO) The main…
- Conditions
- Extracorporeal Membrane Oxygenation Complication, ARDS (Acute Respiratory Distress Syndrome), Intensive Care Medicine, Cardiac Arrest (CA)
- Trial name
- RECOMMEND (NCT06526533)
- Testing
- Liberal RBC Transfusion, Restrictive RBC Transfusion
- Where
- 3 sites in Australia
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Australian and New Zealand Intensive Care Research Centre
Cardiovascular Diseases, Diabetes Mellitus
Improving Medication Safety and CVD Risk Factor Control in Kidney Transplant Recipients
There is a lack of data analyzing the influence of Cardio-vascular Diseases (CVD) risk factor control on graft survival disparities in Black transplant recipients.
- Conditions
- Cardiovascular Diseases, Diabetes Mellitus, Medication Adherence
- Trial name
- NCT02763943
- Testing
- Pharmacist-led, technology enabled education intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Medical University of South Carolina
Stroke
SINEMA Model of Care to Improve the Health of Stroke Patients in Rural China
Despite the significant burden of stroke in rural China, secondary prevention of stroke is scarce. The aim of the study is to develop a system-integrated technology-enabled intervention (SINEMA) model for the secondary prevention…
- Trial name
- SINEMA (NCT03185858)
- Testing
- SINEMA intervention
- Where
- China
- Volunteers
- 1,299 people
- Sponsor
- Duke Kunshan University
Drugs, Non-Prescription, Medication Systems
Over-the-Counter Medication Usage
There are several benefits of over-the-counter medications, yet there is little research evaluating how to increase patient compliance when a health care provider suggests an over-the-counter (OTC) medication.
- Trial name
- NCT00439348
- Testing
- Verbal advice, Prescription
- Where
- United States
- Volunteers
- 246 people, healthy volunteers welcome
- Sponsor
- AdventHealth
Bladder Cancer, Bladder Tumor
A Study of Nivolumab Plus Bempegaldesleukin (Bempeg/NKTR-214) vs Nivolumab Alone vs Standard of Care in Participants With Bladder Cancer That May Have Invaded The Muscle Wall of the Bladder and Who Cannot Get Cisplatin, A Type of Medicine Given To Treat Bladder Cancer
The purpose of the study is to see if treatment with nivolumab plus bempegaldesleukin or nivolumab alone, before and after surgery to remove the bladder, is more effective than surgery alone in participants with high-risk…
- Conditions
- Bladder Cancer, Bladder Tumor, Muscle-Invasive Bladder Cancer
- Trial name
- NCT04209114
- Testing
- Nivolumab, Radical cystectomy (RC), Bempegaldesleukin
- Where
- 116 sites in United States, Argentina and 18 more
- Volunteers
- 114 people
- Sponsor
- Bristol-Myers Squibb
Medication Adherence
Final Prototype Refinement of Adaptive Cell Phone Support
The goal of this feasibility pilot trial is to finalize the design of a mobile health intervention for promoting medication adherence in a population of adolescents and young adults with chronic health conditions.
- Trial name
- ACPS (NCT07084155)
- Testing
- Adaptive Cell Phone Support
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Children's Hospital Los Angeles
Drug Use Stigma in HIV Treatment Clinics
Addressing Drug Use Stigma in Human Immunodeficiency Virus (HIV) Care and Treatment Clinics in Tanzania
The goal of this study is to adapt and pilot an effective health facility HIV stigma-reduction intervention to address drug use stigma in human immunodeficiency Virus (HIV) Care and Treatment clinics (CTCs) in Tanzania, a barrier…
- Trial name
- NCT04863898
- Testing
- Drug-use stigma reduction intervention for HIV care and treatment clinic staff
- Where
- 7 sites in Tanzania
- Volunteers
- 151 people, healthy volunteers welcome
- Sponsor
- RTI International
Hypertension
The Effect of Pharmacist Intervention on Blood Pressure Control
The purpose of the study is to test if a Pharmacist Intervention Program with home blood pressure monitoring (HBPM) improves or controls pharmacological adherence and blood pressure levels in hypertensive patients under…
- Trial name
- AFenPA (NCT01233193)
- Testing
- Health education, Home blood pressure monitoring
- Where
- 2 sites in Spain
- Volunteers
- 140 people
- Sponsor
- Universidad de Granada
HER2-positive Breast Cancer, Diarrhea Caused by Drug
Probiotics for Prevention of Neratinib-Induced Diarrhea in Breast Cancer Patients
This study aims to evaluate the efficacy and safety of probiotics for the prevention of diarrhea in patients with breast cancer receiving the tyrosine kinase inhibitor (TKI) Neratinib.
- Conditions
- HER2-positive Breast Cancer, Diarrhea Caused by Drug, Neratinib
- Trial name
- NCT06892093
- Testing
- Probiotics, Loperamide
- Where
- China
- Volunteers
- 308 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Musculoskeletal Problem, Respiratory Problem
Effectiveness of Western Medicine Outpatient Consultations in Primary Care
Background: Primary care plays an important role in health care delivery, but there is little research on its effectiveness. Western medicine is the most widely used and Traditional Chinese medicine (TCM) is gaining popularity.
- Conditions
- Musculoskeletal Problem, Respiratory Problem, Gastrointestinal Problem, All Primary Care Problem
- Trial name
- NCT00887133
- Where
- China
- Volunteers
- 1,469 people
- Sponsor
- The University of Hong Kong
Osteoporosis, Postmenopausal
Health Literacy's Impact on Exercise Habits and Medication Adherence in Postmenopausal Osteoporosis
Postmenopausal osteoporosis is characterized by low bone mass and increased fracture risk. Treatment includes exercise, nutrition, supplements, and medications like bisphosphonates, denosumab, or hormone replacement therapy.
- Trial name
- NCT06462833
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Gazi University
Endometriosis, Chronic Pain
Therapeutic-educational Physiotherapy on Pain, Physical-functionality and Quality of Life in Women With Endometriosis.
This is a randomized clinical trial that will be carried out in women with endometriosis divided into two groups: the experimental group (EG) that will receive therapeutic-educational physiotherapy, which will combine therapeutic…
- Conditions
- Endometriosis, Chronic Pain, Women's Health
- Trial name
- PHYSIO_ENDOM (NCT06212349)
- Testing
- therapeutic-educational physiotherapy and pain education program, pain education program
- Where
- Spain
- Volunteers
- 62 people
- Sponsor
- University of Valencia
Colon Cancer, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis)
Effectiveness of Health Education as a Nursing Intervention in Improving Quality of Life and Reducing Symptoms of Anxiety and Depression in Ostomy Patients Following Digestive Surgery: A Quasi-Experimental Study.
The proposed project is a prospective quasi-experimental study to be conducted at the Ostomy Clinic of the University Hospital Complex of Santiago de Compostela.
- Conditions
- Colon Cancer, Inflamatory Bowel Disease (Crohn's and Ulcerative Colitis), Colitis Ulcerative
- Trial name
- NCT07347158
- Testing
- Health Education
- Where
- Spain
- Volunteers
- 70 people
- Sponsor
- Hospital Clinico Universitario de Santiago
Coronary Artery Disease
The Role of Clinical Pharmacist in Monitoring Drug Therapy in the Cardiovascular and Coronary Care Units in Libya.
Assessment of role of clinical pharmacist in decreasing morbidity and mortality among coronary artery disease patients.
- Trial name
- BSU (NCT05531552)
- Testing
- clinical pharmacy application
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Beni-Suef University
Intussusception, Emergencies
Point-of-Care Ultrasonography for Intussusception
Pediatric emergency medicine (PEM) physicians are increasingly utilizing point-of-care ultrasound (POCUS). There is currently limited data regarding POCUS evaluation for intussusception in pediatric patients.
- Trial name
- NCT03360643
- Testing
- Point-of-care ultrasound prior to radiology ultrasound, Radiology-performed ultrasound
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- Children's Hospitals and Clinics of Minnesota
Low Back Pain
Low Back Pain Patient Education Evaluation
Back pain is one of the most common of all symptoms. It is also a great cause of days lost from work and visits to health care providers.
- Trial name
- NCT00000408
- Testing
- Patient education evaluation
- Where
- United States
- Volunteers
- 580 people
- Sponsor
- Stanford University
Sexual Health, Health Literacy
Flipped Classroom Sexual Health Education Trial
Sexual health is an integral component of individuals' physical, emotional, mental, and social well-being. Lack of knowledge and cultural taboos negatively affect individuals' ability to make informed decisions and adopt…
- Conditions
- Sexual Health, Health Literacy, Health Education, Flipped Classroom Model in Teaching
- Trial name
- NCT07306208
- Testing
- Flipped learning
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- KTO Karatay University
Medication Adherence, Poly Pharmacy
Itaca App vs. Usual Care for Medication Adherence in Older Adults on Polypharmacy
The goal of this clinical trial is to learn if the use of a mobile app called Itaca improves medication adherence in older adults (aged ≥65) in a home care setting.
- Conditions
- Medication Adherence, Poly Pharmacy, Chronic Disease, Older Adults (65 Years and Older)
- Trial name
- NCT07631676
- Testing
- mobile app, Usual Care Group
- Where
- Italy
- Volunteers
- 120 people
- Sponsor
- University of Roma La Sapienza
Low Back Pain
Efficacy of Metamizole Versus Ibuprofen and a Short Educational Intervention Versus Standard Care in Acute Low Back Pain
The EMISI trial is a randomized, double blind, controlled trial (RCT) using a factorial design in patients with a new low back pain episode.
- Trial name
- EMISI (NCT04111315)
- Testing
- Metamizole Sodium, Ibuprofen 600 mg, Patient education
- Where
- Switzerland
- Volunteers
- 120 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Allergic Rhinitis, Sinusitis
Harnessing Digital Medicine to Improve Allergic Rhinitis Management in Primary Care (DMAR)
This study aims to evaluate the effectiveness of digital tools in managing allergic rhinitis (AR) in primary care settings. AR is a common condition that affects many people's quality of life.
- Trial name
- DMAR (NCT06603935)
- Testing
- QHSLab Digital Tools (AME and ARIS)
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- QHSLab, Inc.
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