Clinical trials: Pharmaceutical Care
Firearm Injury
Store Safely: Rural Firearm Injury Prevention for Families
The researchers are testing a firearm safety prevention strategy tailored for families with children who reside in a rural area. Researchers hypothesize that the intervention will lead to improvements in household firearm storage.
- Trial name
- NCT06719713
- Testing
- Store Safely
- Where
- 2 sites in United States
- Volunteers
- 600 people
- Sponsor
- University of Michigan
HIV Prevention, Pre-exposure Prophylaxis (PrEP)
A Study Evaluating An Integrated Pharmacy Digital Diary and Delivery Strategy to Increase PrEP Use Among MSM and TGW
The PrEP 3D randomized controlled trial (RCT) will study the effectiveness of the PrEP-3D app compared to standard of care for starting pre-exposure prophylaxis (PrEP), continuing PrEP, and adherence to PrEP.
- Conditions
- HIV Prevention, Pre-exposure Prophylaxis (PrEP), Risk Reduction, Adherence, Medication
- Trial name
- PrEP-3D RCT (NCT05474313)
- Testing
- PrEP-3D package, Standard of Care
- Where
- 2 sites in United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
Cardiovascular Diseases, Diabetes
Diabetes Remote Intervention to improVe Use of Evidence-based Medications
A randomized remote, implementation trial in the Mass General Brigham network was performed on 200 patients with T2D at high CV or kidney risk.
- Trial name
- DRIVE (NCT06046560)
- Testing
- SGLT2 inhibitor, GLP-1 RA, Education-First
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Asthma Chronic, Adherence, Medication
Pictograms to Facilitate Comprehension of Medical Indications
SIMAP is a triple-masked randomised trial aimed at assessing whether an automated system of pictograms associated to medical indications results in better comprehension and adherence of said indications.
- Conditions
- Asthma Chronic, Adherence, Medication, Primary Health Care
- Trial name
- SIMAP (NCT05609760)
- Testing
- SIMAP, Usual Care
- Where
- 4 sites in Chile
- Volunteers
- 22 people
- Sponsor
- Universidad de Concepcion
Medication Non-Adherence
Effectiveness Of A Program That Includes Counseling And Patient Support On Adherence To Treatment With Lipitor
Despite extensive reports of the benefits of statins in reducing serious cardiovascular events such as stroke and heart disease in patients with elevated LDL-cholesterol, patients do not take their medicines regularly as…
- Trial name
- NCT01078285
- Testing
- No Patient Counseling, Adherence Counseling
- Where
- 3 sites in United States
- Volunteers
- 500 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Cancer, Adherence, Medication
A Pilot Feasibility Trial of a Tailored Intervention to Improve Adherence in Adolescents and Young Adults With Cancer
A pilot feasibility randomized clinical trial comparing a tailored intervention to uniform standard of care will be conducted. A total of 40 AYAs with cancer will be randomized to one of the two programs.
- Trial name
- NCT05706610
- Testing
- Tailored Program, Feedback Program
- Where
- 3 sites in United States
- Volunteers
- 70 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Depression, Anxiety
Pharmacogenomic Testing to Optimize Antidepressant Drug Therapy
A randomized controlled trial comparing pharmacogenomic guided versus standard pharmacist care to optimize antidepressant drug therapy.
- Conditions
- Depression, Anxiety, Major Depressive Disorder, Generalized Anxiety Disorder
- Trial name
- NCT03591224
- Testing
- Pharmacogenomic Testing, Pharmacist Standard of Care
- Where
- 2 sites in Canada
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- John Papastergiou Pharmacy Ltd
Sepsis
mNGS vs Culture Critically Ill Patients
mNGS is popular in research and recently it has been used clinically to detect microbes in the blood or other secretion in infected patients for quicker ,broad and accurate detection of microbes.
- Trial name
- NCT03760315
- Testing
- blood mNGS (IDSeqTM Ultra); blood Culture
- Where
- China
- Volunteers
- 210 people
- Sponsor
- Southeast University, China
Anticoagulants; Circulating, Hemorrhagic Disorder
MEdication Counselling Models for Outpatient oRal antIcoaguLation
The goal of this clinical trial is to investigate whether telepharmacy-led counselling can improve medication adherence, knowledge, and hospitalisation/mortality compared with pharmacist-led counselling in adult outpatients…
- Trial name
- MEMORIAL (NCT06290440)
- Testing
- Telepharmacy-led counselling, Pharmacist-led counselling
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Migraine
Efficacy of Smartphone Based Digital Application in Improving Headache Related Parameters in Patients With Migraine
Migraine is a common headache disorder and affects 1 in 5 adults during their lifetime. It is a disorder which leads to significantly impaired quality of life, absence from work, loss of productivity in workplace and reduced…
- Trial name
- NCT04984720
- Testing
- Smartphone based digital application
- Where
- India
- Volunteers
- 403 people
- Sponsor
- All India Institute of Medical Sciences
Insomnia, Breast Cancer
Impact of Cognitive Behavioural Therapy for Insomnia on Endocrine Therapy Adherence
The aim of this study is to investigate the impact of cognitive behavioural therapy for insomnia on adherence to endocrine therapy medication in breast cancer survivors.
- Conditions
- Insomnia, Breast Cancer, Adherence, Medication, Quality of Life
- Trial name
- NCT05887297
- Testing
- Cognitive behavioural therapy for insomnia
- Where
- United Kingdom
- Volunteers
- 35 people
- Sponsor
- University of Strathclyde
Asthma, Adherence, Medication
Evaluating Efficacy of Smart Device in Assisting With Inhaler Technique and Adherence
Asthma affects over 10 million children in the U.S., and poses a significant health and cost burden. Metered dose inhaler (MDI) is the most common method of treatment.
- Conditions
- Asthma, Adherence, Medication, Childhood Asthma
- Trial name
- MOMMIASTHMA1 (NCT04250779)
- Testing
- CapMedic smart inhaler device, Video-based guidance
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Landon Pediatric Foundation
Medication Adherence, Antibiotic Resistance, Microbial
7-VINCut Antibiotic Stewardship Intervention to Decrease Duration of Antibiotic Treatment and Carbapenem Use in Surgery
Antimicrobial resistance (AMR) is one of the top ten public health threats facing humanity. The misuse and overuse of antibiotics has been identified as a major factor in the development of drug-resistant pathogens, and 30% of…
- Conditions
- Medication Adherence, Antibiotic Resistance, Microbial, Medication Errors and Other Product Use Errors and Issues
- Trial name
- 7_VINCUT (NCT05813821)
- Testing
- Antimicrobial stewardship in surgery
- Where
- Spain
- Volunteers
- 32,499 people
- Sponsor
- Hospital de Granollers
Medication Errors
Outpatient Prescription Errors: Detection, Analysis, and Impact on Safety
The purpose of this study is to better understand outpatient prescribing errors through clinic and pharmacy-based error reporting systems.
- Trial name
- NCT00256568
- Testing
- reporting system
- Where
- United States
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Biliary Tract Neoplasms
Personalized Medicine for Advanced Biliary Cancer Patients
The object of this trial is to evaluate whether the introduction of a targeted therapy after 4 cycles of the current standard-of-care treatment for advanced biliary cancer is superior to continuing with the standard treatment.
- Trial name
- SAFIR-ABC10 (NCT05615818)
- Testing
- Futibatinib, Ivosidenib, Zanidatamab
- Where
- 69 sites in Belgium, France and 1 more
- Volunteers
- 800 people
- Sponsor
- UNICANCER
Medical Care
Use and Effectiveness of a Model Integrative Care Clinic in an Academic Hospital: Study 1-Survey
Despite widespread and growing popularity of complementary and alternative medicine (CAM) in the US, there currently exist significant gaps in our knowledge regarding CAM use, clinical effectiveness, safety and cost…
- Trial name
- NCT01353560
- Where
- United States
- Volunteers
- 1,509 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Medication Reconciliation
Comparison of MedBook Portal and Usual Care in Medication Reconciliation at Primary Healthcare Upon Hospital Discharge
A randomized controlled trial was conducted to examine the efficacy of the MedBook portal in reducing medication discrepancies after discharge.
- Trial name
- MEDRECON (NCT06517160)
- Testing
- MedBook Portal
- Where
- Malaysia
- Volunteers
- 398 people
- Sponsor
- Ministry of Health, Malaysia
Glioblastoma, IDH-wildtype, MGMT-Methylated Glioblastoma
Lomustine in Addition to Standard of Care in Patients With MGMT Methylated Glioblastoma
Background: Glioblastoma (GBM) is notoriously difficult to treat, with current therapies often extending life by only a few months.
- Trial name
- NCT06419946
- Testing
- Temozolomide, Lomustine
- Where
- 20 sites in Austria, Denmark and 2 more
- Volunteers
- 200 people
- Sponsor
- Vastra Gotaland Region
Transitional Care, Multimorbidity
AdvantAGE: Implementation and Evaluation of an Interprofessional Tranistional Care Model for Frail Older Adults
This clinical trial at the University Department of Geriatric Medicine FELIX Platter in Basel, Switzerland, is designed to evaluate a new transitional care model aimed at helping frail older adults after they get discharged from…
- Conditions
- Transitional Care, Multimorbidity, Geriatric Care
- Trial name
- AdvantAGE (NCT06190288)
- Testing
- Transitional care model
- Where
- Switzerland
- Volunteers
- 250 people
- Sponsor
- Thekla Brunkert
Asthma
Use of Text Messages to Improve Care For Children Following an ED Visit for Asthma
BACKGROUND Asthma is a prevalent and troublesome pediatric condition. In 2013, Emergency Department (ED) providers treated over 3,500 cases of asthma-related complaints at Children's Hospitals and Clinics of Minnesota.
- Trial name
- NCT02436070
- Testing
- Targeted text messages, General text messages
- Where
- 2 sites in United States
- Volunteers
- 195 people
- Sponsor
- Children's Hospitals and Clinics of Minnesota