Clinical trials: Pharmaceutical Care
Acute Kidney Injury, Drug Toxicity
Retrospective Registry Study of Patients With Cancer Treated With High-dose Methotrexate
This retrospective observational study will evaluate high-dose methotrexate patterns of use, supportive care measures used during high-dose methotrexate chemotherapy, along with the incidence of delayed elimination of…
- Trial name
- NCT05899751
- Testing
- High-dose methotrexate, Glucarpidase
- Where
- 5 sites in France, Italy and 1 more
- Volunteers
- 1,000 people
- Sponsor
- Protherics Medicines Development Limited
Risk Reduction Through Family Therapy, Usual Care
Risk Reduction for Drug Use and Sexual Revictimization
The investigator proposes to evaluate Risk Reduction through Family Therapy (RRFT), which integrates: 1) an ecologically-based intervention for treatment of substance abuse behaviors in high risk adolescents, 2) exposure-based…
- Trial name
- RRFT (NCT00998153)
- Testing
- Risk Reduction through Family Therapy
- Where
- United States
- Volunteers
- 135 people
- Sponsor
- Medical University of South Carolina
Medication Reconciliation, Patient Safety
Medication Reconciliation Process in Clinical Practice
This study looks at how reviewing and confirming a patient's medications during a hospital stay can help reduce problems after they go home.
- Conditions
- Medication Reconciliation, Patient Safety, Geriatrics, Hospital Readmission
- Trial name
- NCT07001137
- Where
- France
- Volunteers
- 386 people
- Sponsor
- Centre Hospitalier de Saint-Denis
Adverse Drug Events
Eliminating Risk of Preventable Adverse Drug Events at the Hospital-community Interface of Care
This initiative aims to decrease the risk of medication errors at the hospital-community interface as well as health system utilization following hospital discharge by implementing a pharmacist-led medication reconciliation in…
- Trial name
- CMR (NCT01164137)
- Testing
- Medication Reconciliation
- Where
- Canada
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- Westview Physician Collaborative
Atrial Fibrillation
APIXABAN App Study
The aim of this clinical trial is to evaluate whether the medication reminder app and video call can improve medication adherence to apixaban in patients with AF and comorbidities.
- Trial name
- NCT06903845
- Testing
- video call, Medication reminder app
- Where
- South Korea
- Volunteers
- 40 people
- Sponsor
- Dong-Ju Choi
Hypertension
WEAVE NM: Heart Health and Nutrition for Life
WEAVE NM (Wide Engagement for Assessing Vaccine Equity in New Mexico) is a community-based research initiative working to improve health outcomes in underserved populations, with a current focus on hypertension and food justice.
- Trial name
- WEAVE HHNL (NCT07074145)
- Testing
- Heart Health and Nutrition for Life (HHNL), Self-Measured Blood Pressure
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- University of New Mexico
HIV Infections, Drug Use
INTEGRA: A Vanguard Study of Health Service Delivery in a Mobile Health Delivery Unit
The purpose of this study is to determine the efficacy of using a mobile health delivery unit ("mobile unit") to deliver "one stop" integrated health services - particularly medication for opioid use disorder (MOUD) and…
- Conditions
- HIV Infections, Drug Use, Opioid Use, Opioid-use Disorder
- Trial name
- INTEGRA (NCT04804072)
- Testing
- Medication for opioid-use disorder (MOUD) for opioid-use disorder (OUD), HIV testing, HIV treatment for participants living with HIV not already in care
- Where
- 5 sites in United States
- Volunteers
- 447 people
- Sponsor
- HIV Prevention Trials Network
Medication Errors and Other Product Use Errors and Issues, Adverse Drug Event
Reducing Errors In The Neonatal Intensive Care Unit
This is a monocentric prospective pre and post-intervention study, aiming at analyzing the efficacy of the Computerized Provider Order Entry (CPOE) plus Bar Code Medication Administration (BCMA) as compared to paper order entry…
- Trial name
- SAPHET-i (NCT04193839)
- Testing
- Computerized Provider Order Entry (CPOE) plus Bar Code Medication Administration (BCMA)
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Fondazione Poliambulanza Istituto Ospedaliero
Ulcerative Colitis
Golimumab Dried Blood Spot Analysis
This retrospective multi-centric Belgian prospective trial will involve 10 patients initiating or under maintenance subcutaneous golimumab therapy for moderate-to-severe colitis at the University Hospitals Leuven (Leuven…
- Trial name
- GOUDA (NCT02910375)
- Testing
- Cohort A, Cohort B
- Where
- 2 sites in Belgium
- Volunteers
- 10 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Opioid-Related Disorders
Buprenorphine Group Medical Visits in Primary Care
The primary goal of this research is to improve the effectiveness of buprenorphine maintenance treatment (BMT) within primary care.
- Trial name
- G-BMT (NCT02526212)
- Testing
- G-BMT, Treatment as usual, Buprenorphine
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- Montefiore Medical Center
Transitions of Care, Patient Portals
Interactive Digital Health Tools to Improve Patient Safety in Acute Care
Study 1: The goal of this study is to implement and evaluate an interactive patient-centered discharge toolkit (PDTK) to engage patients and care partners in discharge preparation and communication with providers after discharge.
- Conditions
- Transitions of Care, Patient Portals, General Medicine, Discharge Checklist
- Trial name
- NCT03116074
- Testing
- Interactive Digital Health Tools
- Where
- United States
- Volunteers
- 750 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Depression
Holistic Approaches to Depression
The purpose of the study is to investigate whether yoga or a health education group alleviate depressive symptoms for an individual with a partial response to antidepressant medication.
- Trial name
- HAD (NCT01384916)
- Testing
- Yoga, Healthy Living Workshop
- Where
- United States
- Volunteers
- 121 people
- Sponsor
- Butler Hospital
HIV Infections
SPRING: Safety, Efficacy, Pharmacokinetics of tipRanavir/r IN Race/Gender HIV+ Patients Randomized to TDM or SoC
The primary purpose of this study is to: 1. Demonstrate the safety and efficacy of tipranavir/ritonavir (TPV/r) among a racially diverse HIV+ population (males and females) who are three-class (nucleoside reverse transcriptase…
- Trial name
- NCT00440271
- Testing
- tipranavir, ritonavir, Optimized Background Regimen (OBR)
- Where
- 30 sites in United States, Argentina and 5 more
- Volunteers
- 33 people
- Sponsor
- Boehringer Ingelheim
Diabetes Type 2
Dulce Digital 2.0 - Innovative Diabetes Self-Management in the Digital Age
The proposed research, "Dulce Digital 2.0," will evaluate two mHealth adaptions of Project Dulce that are designed to improve digital health literacy, increase underserved individuals' capacity to access and engage with vital…
- Trial name
- Dulce Digital (NCT05416060)
- Testing
- Dulce Digital Text-Based Education, Project Dulce Telehealth, Project Dulce Live
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Scripps Whittier Diabetes Institute
Meditation, Health Education
Women's Healthy Aging and Menopause; (WHAM)
The present study will examine whether women at high risk for developing hypertension, i.e., post-menopausal status, at least mild psychological distress, and mildly elevated blood pressure, show improvements in these risk…
- Trial name
- NCT07314827
- Testing
- Transcendental Meditation (TM), Women's Health Education (WHE)
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Bronchial Asthma, Adherence, Medication
Efficacy of a Phone Application on Treatment Adherence in Asthmatic Patients in Upper Egypt
asthma adherence is mandatory for disease control
- Trial name
- NCT06233123
- Testing
- the Medisafe android application (https://www.medisafe.com).
- Volunteers
- 180 people
- Sponsor
- Assiut University
Breast Cancer
eHealth Intervention for Medication Adherence in Breast Cancer Survivors
Tamoxifen and aromatase inhibitors are two oral hormonal therapies (OHT) that decrease the risk of breast cancer recurrence by over 30 %. Their efficacy however strongly depends on the duration of use (5 to 10 years).
- Trial name
- Edherence (NCT05324020)
- Testing
- Medication adherence eHealth intervention
- Where
- 2 sites in Luxembourg
- Volunteers
- 3 people
- Sponsor
- Luxembourg Institute of Health
Hematopoietic Stem Cell Transplantation
Cyclosporine (CSA) Level in Blood Samples Collected From Different Lines
The purpose of this study is to verify whether differences exist in cyclosporine levels between the samples collected through peripheral venous access, the catheter line used to infuse the drug and the line not used for infusion…
- Trial name
- NCT01598688
- Testing
- Blood collection immediately after interrupting CSA infusion, Blood collection five minutes after interrupting CSA infusion
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
Polypharmacy, Deprescribing
Spread and Scale of a Polypharmacy App
Medication overload is an epidemic causing widespread harm, particularly to older Canadians. While most prescriptions are intended to help people live longer and healthier lives, taking multiple medications can increase frailty…
- Conditions
- Polypharmacy, Deprescribing, Adverse Drug Event
- Trial name
- NCT04762303
- Testing
- MedReviewRx
- Where
- 5 sites in Canada
- Volunteers
- 1,000 people
- Sponsor
- Centre for Innovation and Research in Aging, Canada
Adherence, Medication, Risk Behavior
DOT Diary Optimization Pilot: A Pilot Study to Optimize the DOT Diary App to Measure PrEP Adherence
The researchers are working with a technology company, AiCure, to develop a smartphone app, DOT Diary, which combines two drug adherence strategies.
- Conditions
- Adherence, Medication, Risk Behavior, Pre-Exposure Prophylaxis, HIV Prevention
- Trial name
- NCT03387462
- Testing
- Emtricitabine / Tenofovir Disoproxil Oral Tablet, DOT Diary mobile app
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Public Health Foundation Enterprises, Inc.
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