Clinical trials: Pharmaceutical Care
Tuberculosis, Drug-resistant Tuberculosis
An Evaluation of Traditional Directly Observed Therapy (DOT) and Electronic DOT for TB Treatment
This study is a U.S.-based, 1 site (with 4 clinical settings), randomized controlled trial (with funding from the Centers for Disease Control and Prevention's (CDC) Antibiotic Resistance Solutions Initiative) that will be…
- Conditions
- Tuberculosis, Drug-resistant Tuberculosis, Adherence, Medication, Adherence, Patient
- Trial name
- NCT03266003
- Testing
- Electronic DOT, In-person DOT
- Where
- 4 sites in United States
- Volunteers
- 216 people
- Sponsor
- Centers for Disease Control and Prevention
Type 2 Diabetes Mellitus
Shared Decision Making Between Patients and GPs in the Treatment of Type 2 Diabetes in Primary Care.
Background: Less than 20% of type 2 diabetes mellitus (T2DM) patients in different healthcare settings achieve all treatment goals to prevent cardiometabolic disease.
- Trial name
- NCT02285881
- Testing
- Shared decision making
- Where
- Netherlands
- Volunteers
- 153 people
- Sponsor
- UMC Utrecht
Diabetes, Hypertension
Pharmacy Interventions to Improve Chronic Disease Medication Refill
Compare the effectiveness of 3 strategies by pharmacists to decrease the time to refill of prescriptions for common chronic diseases (diabetes, hypertension, hyperlipidemia, heart failure, depression, psychoses).
- Conditions
- Diabetes, Hypertension, Hyperlipidemia, Heart Diseases
- Trial name
- NCT00469365
- Testing
- pharmacist contact with the patient via telephone, Pharmacist contact with the patient's physician via fax, Usual care
- Where
- United States
- Volunteers
- 3,048 people
- Sponsor
- Medical University of South Carolina
Fragility
Geriatrician-performed Comprehensive Geriatric Care in an Outpatient Community Rehabilitation Unit
Introduction: Older adults with multiple illnesses represent the fastest growing sector of society and make increasing demands on all sectors of the health care system, particularly in outpatient community rehabilitation units…
- Trial name
- GCGCCRU (NCT01506219)
- Testing
- Geriatrician-performed CGC
- Where
- 2 sites in Denmark
- Volunteers
- 368 people
- Sponsor
- Aarhus University Hospital
Drug Hypersensitivity
Allergy Testing of Patients Labeled as Penicillin Allergic
Patients labeled as penicillin allergic, rarely have this confirmed and being labeled as "penicillin allergic" is associated with increased health care costs, adverse effects and antibiotic resistance.
- Trial name
- NCT02983630
- Testing
- Penicillin allergy testing
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Albany Medical College
Anesthesia
Survey of Anesthesiology Residents' Perceptions of Critical Care Medicine as a Career
This study's goal is to investigate the reasons behind the decline in interest in critical care fellowships among anesthesia residents.
- Trial name
- NCT05566067
- Testing
- Survey
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Stanford University
Off-label Use of Atypical Antipsychotic Drugs
iADAPT: Off Label Use of Antipsychotics in the Nursing Home
The investigators propose to evaluate the effectiveness of 3 different methods to promote the dissemination and adoption of evidenced-based review guides into the nursing home setting.
- Trial name
- NCT01347619
- Testing
- Toolkit only with Web Access to Online Version, Toolkit, Periodic Audit/Feedback, Educational Messages, Items in Arm 2 plus Academic Detailing Program
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Healthy
Rationalisation of Polypharmacy in the Elderly by the RASP Instrument
The aim of this study is to determine whether a clinical pharmacist using the RASP list (RASP = Rationalisation of home medication by an adjusted STOPP-list in older patients; STOPP = Screening Tool of Older Persons' potentially…
- Trial name
- RASP (NCT01513265)
- Testing
- Pharmaceutical care plan, mostly based on the RASP
- Where
- Belgium
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Preventative Medicine
Using a Telehealth and Shared Decision-Making Model to Address Preventative Medicine Strategies Among Communities in Louisiana
This study is a 12-18 month behavioral intervention study to assess the impact of enrolling individuals a clinical pharmacist run Telehealth education focused on wellness and preventive health strategies.
- Trial name
- NCT05676970
- Testing
- Telehealth: Personalized Preventative Medicine Strategies, TeleHealth: Preventative Medicine Education
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Xavier University of Louisiana.
Smoking Cessation
Nicotine Replacement Provided at a Tertiary Care Hospital
The purpose of this study is to show that a patient-centered survey asking about smoking habits, with the option for nicotine replacement therapy (NRT) will increase the prescription rates among health care providers (HCP).
- Trial name
- N-PATCH (NCT01614054)
- Testing
- Survey of patient's smoking habits
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University of British Columbia
Depression
Mobile Technology to Engage and Link Patients and Providers in Antidepressant Treatment
The goal of this project is to develop and pilot a mobile smartphone delivered intervention that will improve antidepressant medication care by providing medication adherence monitoring and support to the patient, feedback on…
- Trial name
- Medlink RCT (NCT01909973)
- Testing
- MedLink System
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwestern University
Ventriculitis, Infectious
Evaluation of a TDM Program for Intensive Care Patients in the Cerebrospinal Fluid
Therapeutic drug monitoring of antibiotics in critically ill patients is a present research topic of the last ten years. Research results have shown subtherapeutic blood concentrations in those patients.
- Trial name
- EMIL (NCT04426383)
- Where
- Germany
- Volunteers
- 32 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Cancer
Medico-economic Evaluation of the ONCORAL Program for Ambulatory Patients Under Oral Anticancer Drugs Versus Usual Care
Economic impact of cancer treatments is increasing for years: increase of number of patients (385 000 new occurrences in 2015), increase of life expectancies, chronicization of diseases and increase of therapeutic innovation…
- Trial name
- ONCORAL-PRME (NCT03660670)
- Testing
- ONCORAL therapeutic education, Standard of care
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Hospices Civils de Lyon
Hypertension, Public Health; Nursing Staff
Nursing Interventions Based on Protection Motivation Theory in Hypertensive Patients
Hypertension is a major global public health problem. In order to be successful in hypertension management, patients should receive timely and accurate diagnosis, acquire healthy lifestyle habits, start antihypertensive drug…
- Trial name
- NCT05995977
- Testing
- Nursing interventions based on protection motivation theory in patients with hypertension
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Necmettin Erbakan University
Opioid Use Disorder, Opioid Withdrawal
Medically Supervised Ibogaine With 12-Month Digital Recovery Support for Opioid Use Disorder
IBO-CARE is a single-site Phase 1/2a study evaluating the safety, tolerability, feasibility and preliminary outcomes of medically supervised ibogaine with 12 months of recovery support in adults with moderate-to-severe opioid use…
- Conditions
- Opioid Use Disorder, Opioid Withdrawal, Substance Use Disorders
- Trial name
- IBO-CARE (NCT07871877)
- Testing
- Ibogaine Hydrochloride, Extended-release naltrexone injection, 380 mg, My-E-Health SENTINEL Digital Monitoring and Human-Gated Escalation Platform
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Clive Michelsen
COVID-19
Effect of CytoSorb Adsorber on Hemodynamic and Immunological Parameters in Critical Ill Patients With COVID-19
This prospective randomized single Center study investigates to what extent the physical elimination of the inflammatory mediators using the CytoSorb adsorber reduces the morbidity of severely and critically ill patients with…
- Trial name
- CYTOCOV-19 (NCT04344080)
- Testing
- CytoSorb-Therapy
- Where
- Germany
- Volunteers
- 24 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Heart Failure
Palliative Care for Heart Failure Patients
The purpose of this study is to assess the impact of palliative care consultation on quality of life and symptom management for patients hospitalized with acute heart failure with a randomized control trial at Abbott Northwestern…
- Trial name
- NCT01519479
- Testing
- Palliative Care Consultation, Control
- Where
- United States
- Volunteers
- 232 people
- Sponsor
- Allina Health System
Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy
MH-Rx Study (Baby on Board: Check-in on You, Your Medication, & Your Blood Pressure)
This randomized controlled trial will evaluate whether adding Community Health Worker (CHW)/Social Worker (SW)-led support for non-medical health related needs (NMHRN) and clinician-led Medication Therapy Management (MTM) to…
- Conditions
- Hypertensive Disorders of Pregnancy, Chronic Hypertension in Pregnancy, Gestational Hypertension
- Trial name
- NCT07842341
- Testing
- Community Health Worker (CHW)/Social Worker (SW)-led non-medical health related needs (NMHRN) intervention + Clinician-Led Medication Therapy Management (MTM) with remote blood pressure monitoring, Active Comparator (Control group)
- Where
- United States
- Volunteers
- 158 people
- Sponsor
- Texas Southern University
Medication Adherence
Reminders Through Association & Prescription Adherence
The purpose of this study is to develop behavioral interventions that provide effective tools that policy makers can use to help individuals avoid forgetting to follow-through on important behaviors and for individuals to use to…
- Trial name
- NCT03697083
- Testing
- Reminders Through Association, Active Control, Baseline Control
- Where
- United States
- Volunteers
- 777 people
- Sponsor
- University of Pennsylvania
Polypharmacy
Medication Monitoring for Older Adults in Primary Care
Polypharmacy has the potential to harm older adults by causing cognitive impairment, falls, and hospitalisations. Many adverse drug reactions could be prevented with closer monitoring.
- Trial name
- NCT04663360
- Testing
- Adverse Drug Reaction (ADRe) Profile
- Where
- United Kingdom
- Volunteers
- 19 people
- Sponsor
- Swansea University
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