Clinical trials: Pharmaceutical Care
Multimorbidity
Co-design of a Seamless Person-centered Intervention to Optimize Medication Use Across Healthcare Levels
Multiple long term conditions entails various needs for complex medication treatment, which is a huge clinical challenge considering medication interactions and disease-medication interactions.
- Trial name
- CIRCLE (NCT05421143)
- Where
- Norway
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Malin Olsen Syversen
Opioid Addiction
Integrating Support Persons Into Recovery
INtegrated Support Persons Into Recovery (INSPIRE) is a 4-year research project that tests whether integrating a patient's support person into a patient's treatment with Buprenorphine/Naloxone can improve outcomes.
- Trial name
- INSPIRE (NCT04239235)
- Testing
- CRAFT
- Where
- 6 sites in United States
- Volunteers
- 439 people, healthy volunteers welcome
- Sponsor
- Stanford University
Human Immunodeficiency Virus, Alcohol-Related Disorders
Project Khanya: Peer-Delivered Intervention to Improve HIV Medication Adherence and Substance Use in South Africa
The purpose of this study is to evaluate a stepped care behavioral intervention for HIV medication adherence and substance use ("Khanya") integrated into an HIV primary care setting in South Africa.
- Conditions
- Human Immunodeficiency Virus, Alcohol-Related Disorders, Drug Use, Substance Use
- Trial name
- NCT05933226
- Testing
- Khanya
- Where
- South Africa
- Volunteers
- 160 people
- Sponsor
- University of Maryland, College Park
Diabetes Type II
A Retrospective Study of Cardiovascular Events Related to the Use of Glucose Lowering Drug Treatment in Primary Care
To describe the type II diabetes population in primary care with special reference to treatment, other diseases and mortality during the last decade.
- Trial name
- ROSE (NCT01121315)
- Where
- Sweden
- Volunteers
- 58,326 people
- Sponsor
- AstraZeneca
Community Health Education
Evaluation of Health Education Theater
This study evaluates the feasibility and the potential positive health impacts of a novel "health education theater," which will task participants of a health education program to create an original 10-minute theater that is…
- Trial name
- NCT03759015
- Testing
- Health education
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Multiple Myeloma
A Study to Evaluate Subcutaneous TAK-079 Added to Standard of Care Regimens in Participants With Newly Diagnosed Multiple Myeloma (NDMM)
The purpose of this original study is to determine the recommended phase 2 dose (RP2D) of TAK-079 when administered to participants with NDMM in combination with the backbone treatment regimen.
- Trial name
- NCT03984097
- Testing
- TAK-079, Lenalidomide, Dexamethasone
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Takeda
Acute Decompensated Heart Failure
Effect of Providing Education and Patient's Inferior Vena Cava Ultrasound Images on Adherence to a Heart Failure Regimen
Heart failure is a common, costly, and disabling condition characterized by recurrent exacerbations. Episodes of acute decompensated heart failure (ADHF) account for the largest proportion of admissions and 30-day readmissions to…
- Trial name
- NCT03488979
- Testing
- educational interventional group
- Volunteers
- 100 people
- Sponsor
- Johns Hopkins University
Cancer
Medico-economic Evaluation of the ONCORAL Program for Ambulatory Patients Under Oral Anticancer Drugs Versus Usual Care
Economic impact of cancer treatments is increasing for years: increase of number of patients (385 000 new occurrences in 2015), increase of life expectancies, chronicization of diseases and increase of therapeutic innovation…
- Trial name
- ONCORAL-PRME (NCT03660670)
- Testing
- ONCORAL therapeutic education, Standard of care
- Where
- France
- Volunteers
- 215 people
- Sponsor
- Hospices Civils de Lyon
Drug Overdose, Metformin
Clinical and Biological Signs of Dapagliflozin Overdose in ICU Patients With Metformin Poisoning
This study looks at patients admitted to intensive care for drug poisoning involving metformin, a common diabetes medication. Researchers will compare two groups: patients who overdosed on metformin alone and those who took both…
- Conditions
- Drug Overdose, Metformin, Dapagliflozin, Lactic Acidosis
- Trial name
- NCT07193069
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Centre Hospitalier de Saint-Denis
COVID-19
The Effects of Web-Based Training for Covid-19 Patients on Symptom Management, Medication Compliance and Quality of Life
2019 coronavirus disease (Covid-19) is a virus that emerged in Wuhan, China in late 2019, spread all over the world in a short time and causes severe acute respiratory syndrome and pneumonia.
- Trial name
- NCT04824469
- Testing
- intervention group
- Volunteers
- 128 people
- Sponsor
- Eskisehir Osmangazi University
Type 2 Diabetes Mellitus
Dapagliflozin in Type 2 Diabetes Patients, a Retrospective Cohort Study From Turkey
Background/Rationale: Objectives and Hypotheses: To describe characteristics of patients with type 2 diabetes (T2D) prescribed dapagliflozin in routine internal medicine and endocrinology outpatient clinical care in Turkey; to…
- Trial name
- DAPA-TURK (NCT03407196)
- Testing
- Forxiga
- Where
- Turkey (Türkiye)
- Volunteers
- 1,683 people
- Sponsor
- AstraZeneca Turkey
Bipolar Disorder, Medication Adherence
CAE Plus LAI in Individuals With Bipolar Disorder at Risk for Treatment Non-adherence (BD-CAEL)
This is a prospective study using customized adherence enhancement (CAE) and long-acting injectable (LAI) antipsychotic in 30 individuals with bipolar disorder (BD) at risk for treatment non-adherence.
- Conditions
- Bipolar Disorder, Medication Adherence, Medication Non Adherence
- Trial name
- NCT03408873
- Testing
- Abilify Maintena, Customized Adherence Enhancement (CAE)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Martha Sajatovic
Cardiogenic Shock, Cardiogenic Shock Acute
Prospective Validation of the STOPSHOCK Score - Artificial Intelligence Based Predictive Scoring System to Identify the Risk of Developing Cardiogenic Shock (CS) in Patients Suffering From Acute Coronary Syndrome (ACS)
Cardiogenic shock (CS) is a severe complication of acute coronary syndrome (ACS) with mortality approaching 50% despite the use of percutaneous mechanical circulatory support devices (pMCS).
- Conditions
- Cardiogenic Shock, Cardiogenic Shock Acute, Cardiogenic Shock Post Myocardial Infarction, Acute Coronary Syndrome (ACS) Undergoing Percutaneous Coronary Intervention (PCI)
- Trial name
- STOPSCHOCK (NCT07090382)
- Where
- Slovakia
- Volunteers
- 1,046 people
- Sponsor
- Premedix Academy
Diabetes, Hypertension
Pharmacists Improving Refugees' Adherence and Knowledge of Their Chronic Medications
This study is a randomized, controlled, single-blinded clinical study which conducted over six months (May to October 2016) in different Jordanian cities, where most of Syrian refugees reside.
- Conditions
- Diabetes, Hypertension, Dyslipidemias, Cardiac Disease
- Trial name
- NCT04554810
- Testing
- Medication Management Service
- Volunteers
- 106 people
- Sponsor
- Prof. Iman Basheti
Sarcopenia, Malnutrition
EAMA Sarcopenia in Acute Care Patients in 9+European Countries
This collaborative study in 9 geriatrics units across Europe aims to apply emerging research to clinical practice, following the "Action-Research Philosophy" (11).
- Trial name
- EAMA9+ (NCT04039620)
- Testing
- Observational study, no interventions expected
- Where
- Spain
- Volunteers
- 366 people
- Sponsor
- Parc de Salut Mar
Medication Adherence
Improvement in Medication Adherence Through the Implementation of Personalized Nudges: the ENCOURAGE Trial
This study will determine whether a complex, data-driven protocol for assessing patient needs and providing "nudges" (reminders to be adherent with medication prescriptions) improves adherence with cardiovascular medications.
- Trial name
- ENCOURAGE (NCT02490423)
- Testing
- Nudges Intervention
- Where
- United States
- Volunteers
- 186 people
- Sponsor
- Intermountain Health Care, Inc.
End Stage Renal Disease
Impact of Clinical Pharmacy Services on Medication Cost and Hospitalization Rates in Hemodialysis Patients
The purpose of this study is to evaluate the effects of pharmaceutical care interventions in the ambulatory hemodialysis patients over a one-year period.
- Trial name
- NCT05952388
- Testing
- Behavioral Patient care
- Sponsor
- University of New Mexico
Parkinson Disease, Medication Compliance
Medication Responsiveness in Parkinson's Disease
Up till now, dopaminergic replacement is considered as the gold standard for the symptomatic treatment of motor symptoms in Parkinson's disease (PD).
- Conditions
- Parkinson Disease, Medication Compliance, Tapping Task, Smartphone
- Trial name
- NCT04185740
- Testing
- CloudUPDRS - Tapping Task
- Where
- Belgium
- Volunteers
- 33 people
- Sponsor
- KU Leuven
High-risk Surgery
Association of Intraoperative Hemodynamic Characteristics to Postoperative Complications and Mortality
Worldwide, about 400 million major surgeries are performed annually. The scarce data available in the literature still suggest high postoperative morbidity and mortality, even in Europe.
- Trial name
- HeCoMo (NCT06355362)
- Volunteers
- 1,000 people
- Sponsor
- Kliniken Essen-Mitte
Chronic Kidney Diseases, Adherence, Medication
Leveraging mHealth Messaging to Promote Adherence in Teens With CKD
The overall goal of this study is to develop and test effectively framed mobile health (mHealth) messages to promote medication adherence in teens with chronic kidney disease (CKD).
- Conditions
- Chronic Kidney Diseases, Adherence, Medication, Communication
- Trial name
- NCT03651596
- Testing
- mHealth Messaging Intervention Group, Standard mHealth Messaging Group
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Johns Hopkins University