Clinical trials: Pharmaceutical Care
Psychosis, Medication Adherence
Piloting MOL Intervention for Neuroleptic Decision Making
The aim of the current study is to pilot a novel intervention to help people explore their decision making around the use of neuroleptic medication.
- Trial name
- NCT03537040
- Testing
- Method of Levels
- Where
- 2 sites in United Kingdom
- Volunteers
- 5 people
- Sponsor
- University of Manchester
Drug Utilization Review
Medication Reviews in Elderly in Primary Care
The study is a follow-up of a randomized controlled study performed in 2011-2012 with medication reviews in elderly patients in Sweden. Additional data about mortality and hospital admissions have been collected.
- Trial name
- NCT04040855
- Testing
- Medication review
- Volunteers
- 369 people
- Sponsor
- Region Skane
HIV, Adolescent Development
Health Improvement for Baltimore Youth
Preliminary data from the investigators' National Center for Complementary and Alternative Medicine (NCCAM)-funded R21 on mindfulness-based stress reduction (MBSR) in HIV-infected youth suggest an association between mindfulness…
- Conditions
- HIV, Adolescent Development, Adolescent Behavior, Medication Adherence
- Trial name
- NCT02624193
- Testing
- MBSR Program, HT Program
- Where
- 2 sites in United States
- Volunteers
- 97 people
- Sponsor
- Johns Hopkins University
Infection, Bacterial, Antibiotic Side Effect
Medical Device (MD) Derived Pharmacokinetic (PK) Parameters for Vancomycin (MD-PK)
Getting the right dose of antibiotic promptly is an important part of treating infections. Unfortunately, when an infection is severe (sepsis) the body changes how it processes antibiotics.
- Conditions
- Infection, Bacterial, Antibiotic Side Effect, Antibiotic Resistant Infection, Sepsis
- Trial name
- MD-PK (NCT05950984)
- Testing
- Drug Infusion Pump Monitoring
- Where
- United Kingdom
- Volunteers
- 30 people
- Sponsor
- St George's, University of London
Type2 Diabetes, Medication Adherence
Improving Diabetes Medication Adherence for African Americans in Madison and Milwaukee Through Peer Support
The burden of diabetes is higher among African Americans (AAs) in Wisconsin as hospitalization rates for diabetes complications such as stroke and amputations are four times higher than whites and has worsened by 334% since 2011.
- Conditions
- Type2 Diabetes, Medication Adherence, Medication Nonadherence, Peer Support
- Trial name
- NCT04028076
- Testing
- Peers Supporting Health-Literacy, Self Efficacy, Advocacy and Adherence
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Wisconsin, Madison
Nursing Education, Presentation Skills
Effects of Pecha Kucha on Presentation Skills in Nursing Students
Background: Pecha Kucha may support concise and organized health education presentations, but its contribution when added to conventional PowerPoint presentations remains unclear.
- Conditions
- Nursing Education, Presentation Skills, Pecha Kucha
- Trial name
- NCT07767786
- Testing
- PowerPoint + Pecha Kucha summary, PowerPoint only
- Where
- Turkey (Türkiye)
- Volunteers
- 272 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Hematopoietic Stem Cell Transplantation
Cyclosporine (CSA) Level in Blood Samples Collected From Different Lines
The purpose of this study is to verify whether differences exist in cyclosporine levels between the samples collected through peripheral venous access, the catheter line used to infuse the drug and the line not used for infusion…
- Trial name
- NCT01598688
- Testing
- Blood collection immediately after interrupting CSA infusion, Blood collection five minutes after interrupting CSA infusion
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- University of Sao Paulo
ADHD, Substance Use Disorders
Integrated Treatment for Adolescents With ADHD
Attention-Deficit/Hyperactivity Disorder (ADHD) exists in 20-50% of the 3 million adolescents annually enrolled in outpatient mental health and substance use treatment.
- Trial name
- CASALEAP IT2A (NCT02420990)
- Testing
- Medication Integration Protocol (MIP), Changing Academic Support in the Home for Adolescents with ADHD (CASH-AA)
- Where
- United States
- Volunteers
- 145 people
- Sponsor
- The National Center on Addiction and Substance Abuse at Columbia University
Adverse Events
Strategies for Improving Proton Pump Inhibitors (PPIs) Prescription Associated to Non-steroidal Anti-inflammatory Drugs (NSAIDs)
Background Despite the low prevalence of serious complications associated with non-steroidal anti-inflammatory drugs (NSAIDs) use, there is a widespread use of gastroprotective proton pump inhibitors (PPIs) in order to prevent…
- Trial name
- NCT01128127
- Testing
- Group education, audit-feedback and computer support, Audit-feedback and computer support, Control
- Where
- Spain
- Sponsor
- Servicio Canario de Salud
Pediatric Palliative Care, Life Limiting Conditions
Experiential and Relaxation Virtual Reality as a Tool for Easing Anxiety in Seriously Ill Children
The goal of this clinical trial is to assess the use of experiential and relaxation virtual reality (VR) interventions in easing anxiety and other distress symptoms in children with life-limiting and/or life-threatening…
- Conditions
- Pediatric Palliative Care, Life Limiting Conditions, Life Threatening Diseases
- Trial name
- NCT06915883
- Testing
- Relaxation virtual reality (VR), Experiential virtual reality (VR)
- Where
- Czechia
- Volunteers
- 50 people
- Sponsor
- National Institute of Mental Health, Czech Republic
Kidney Transplantation, Medication Non-Adherence
Kidney Transplant Immunosuppressive Therapy Adherence Trial (KITE)
This randomized controlled interventional study aims to evaluate the effect of structured education and telephone counseling on immunosuppressive medication adherence among kidney transplant recipients.
- Conditions
- Kidney Transplantation, Medication Non-Adherence, Immunosuppressive Therapy, Renal Transplant Recipients
- Trial name
- KITE (NCT07364123)
- Testing
- Education and Telephone Counseling Program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- University of Gaziantep
Asthma in Children, Nonadherence, Medication
Symptom-driven ICS/LABA Therapy for Adolescent Patients With Asthma Non-adherent to Daily Maintenance Inhalers
Inhaler nonadherence is a common problem that has been estimated to account for approximately 60% of all asthma-related hospitalizations.
- Trial name
- NCT05689983
- Testing
- Maintenance ICS and Symptom Driven SABA, Symptom-driven budesonide/formoterol combination
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Washington University School of Medicine
Healthy
Effectiveness of a Multifactorial Intervention to Improve Diet and Physical Activity in Diabetics From Primary Care
This is a randomized, clinical trial aimed at diabetics between 25-70 years (with no cardiovascular disease) selected at urban primary care health clinics in Salamanca (Spain).
- Trial name
- NCT02991079
- Testing
- Intervention group, Control: Lifestyle counseling
- Where
- Spain
- Volunteers
- 200 people
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Cancer Pain, Opioid Use
Epidural Association of Morphine and Ropivacaine for Cancer Pain Treatment
In 2012, more than 14 million cases of cancer were diagnosed worldwide, with the forecast for 2025 exceeding 20 million. Pain is the most critical symptom that accompanies cancer.
- Conditions
- Cancer Pain, Opioid Use, Cost Analysis, Palliative Care
- Trial name
- NCT05558397
- Testing
- Interventional Group (Epidural morphine), Control Group (Oral morphine)
- Where
- Brazil
- Volunteers
- 32 people
- Sponsor
- Universidade Federal de Alfenas
Platelet Aggregation Inhibitors, Hydroxymethylglutaryl-coa Reductase Inhibitors
The Compliance of DAPT and Statins on Clinical Outcomes in Percutaneous Coronary Intervention Patients
A nationwide retrospective cohort study. To investigate the real world medication compliance and the relation with clinical outcomes.
- Conditions
- Platelet Aggregation Inhibitors, Hydroxymethylglutaryl-coa Reductase Inhibitors, Compliance, Medication, Adherence, Medication
- Trial name
- CPPCI (NCT03785509)
- Testing
- DAPT, Statin
- Where
- South Korea
- Volunteers
- 47,291 people
- Sponsor
- Samsung Medical Center
Opioid Overdose, Opioid Use
Machine-Learning Prediction and Reducing Overdoses With EHR Nudges
The goal of this cluster randomized clinical trial is to test a clinician-targeted behavioral nudge intervention in the Electronic Health Record (EHR) for patients who are identified by a machine-learning based risk prediction…
- Conditions
- Opioid Overdose, Opioid Use, Opioid Use Disorder, Opioids
- Trial name
- mPROVEN (NCT06806163)
- Testing
- EHR-Embedded Elevated-Risk Flag, EHR-Embedded Elevated-Risk Flag with Behavioral Nudges, Usual Care
- Where
- United States
- Volunteers
- 1,350 people
- Sponsor
- University of Pittsburgh
Type II Diabetes
Effectiveness of an mHealth Mobile App
Type II diabetes is a serious challenge for Pakistan. Not using medications properly increases healthcare costs and diabetes-related deaths.
- Trial name
- mHealth (NCT06387433)
- Testing
- mobile app use
- Where
- Pakistan
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Dow University of Health Sciences
Need to Refer the Patient to the Hospital Emergency Department
Artificial Intelligence Triage of Patients Requiring Emergency or Unscheduled Care Who Need to be Referred to Hospital
For several decades, hospital emergency departments have been experiencing congestion, sometimes reaching saturation point, where they are no longer able to fulfil their primary mission: to prioritise patients requiring immediate…
- Trial name
- TRIAGE (NCT07428109)
- Where
- France
- Volunteers
- 40,680 people
- Sponsor
- SOS Médecins Grand Paris
Ulcerative Colitis
Methods of Improvement Adherence With Therapy in Ulcerative Colitis.
Ulcerative Colitis is associated with a significantly increased risk of colorectal cancer. This risk can be reduced through regular medication with 5ASA compounds.
- Trial name
- NCT00398593
- Testing
- Range of electronic pill dispensers with alarms
- Volunteers
- 80 people
- Sponsor
- University Hospitals, Leicester
Central Venous Catheterization, Ultrasound
Point of Care Echocardiography Versus Chest Radiography for the Assessment of Central Venous Catheter Placement
A prospective study to compare the use of point of care echocardiography versus routine chest radiography for the assessment of central venous catheter placement.
- Conditions
- Central Venous Catheterization, Ultrasound, Emergency Medicine, Critical Care
- Trial name
- NCT02661607
- Testing
- Point of care echocardiography, Central venous catheter placement, Chest radiography
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Göttingen
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