Clinical trials: Pharmaceutical Care
Acute Myocardial Infarction
Randomized, Single Center Study About the Impact of an E-learning Dedicated to Myocardial Infarction Patient
Acute coronary syndrome (ACS) is still one of the major cause of morbi-mortality in Europe. After an ACS, patients should be treated with secondary prevention medication to reduce the risk of recurrence.
- Trial name
- NCT03949608
- Testing
- E-learning
- Where
- Switzerland
- Volunteers
- 67 people
- Sponsor
- University of Lausanne Hospitals
Enhance Patient Safety, Nurse Physician Relations
Advanced Airway Management Among Primary Care Health
Background: Advanced airway management is a critical component of advanced life support (ALS). Supraglottic airway devices (SADs) represent an effective and safe alternative to endotracheal intubation in emergency settings…
- Conditions
- Enhance Patient Safety, Nurse Physician Relations, Physician-Nurse Relations
- Trial name
- MMC26 (NCT07788690)
- Testing
- Educative Intervention
- Where
- Spain
- Volunteers
- 538 people
- Sponsor
- Universitat Jaume I
Hepatitis C, Diagnostic Self Evaluation
HCV Self-testing in Georgia
Self-testing with easy-to-use rapid diagnostic tests has been successfully used for diseases such as HIV. The availability of self-testing has been shown to increase testing rates and testing acceptability in diverse populations…
- Trial name
- NCT04961723
- Testing
- (OraQuick® HCV Self-Test
- Where
- 6 sites in Georgia
- Volunteers
- 1,250 people, healthy volunteers welcome
- Sponsor
- Foundation for Innovative New Diagnostics, Switzerland
Medication Adherence, Depressive Symptoms
Testing THRIVE 365 for Black Sexual Minority Men (On The Daily)
The primary goal of this study is to test a minority stress model of psychological health outcomes for Black sexual minority men (BSMM) while using and not using a novel intervention named THRIVE 365.
- Conditions
- Medication Adherence, Depressive Symptoms, Anxiety Symptoms, Emotion Regulation
- Trial name
- OTD (NCT05376397)
- Testing
- iTHRIVE 365
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Tuberculosis
Electronic Pillbox-enabled SAT Versus DOT for TB Medication Adherence and Treatment Outcomes
To address the multifaceted challenges associated with tuberculosis (TB) in-person directly observed therapy (DOT), the World Health Organization recently recommended countries maximize the use of digital adherence technologies.
- Trial name
- SELFTB (NCT04216420)
- Testing
- MERM-observed self-administered therapy
- Where
- Ethiopia
- Volunteers
- 114 people
- Sponsor
- Addis Ababa University
Hypertension
Medication Adherence in Hypertension Study
The purpose of this study is to test an intervention to help older adults do a better job of following blood pressure medication regimens prescribed by their health care providers.
- Trial name
- NCT00688350
- Testing
- Behavioral feedback
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Missouri-Columbia
Acute Respiratory Failure, Shock
Impact of Early Enteral vs. Parenteral Nutrition on Preservation of Gut Mucosa Integrity in Patients Requiring Mechanical Ventilation and Catecholamine
To demonstrate that a strategy involving early first-line enteral nutrition is associated with improved preservation of gut mucosa integrity, as assessed based on the plasma citrulline level at H72, compared to a strategy…
- Trial name
- NCT03852940
- Testing
- Parenteral nutrition, Enteral Nutrition
- Where
- 6 sites in France
- Volunteers
- 169 people
- Sponsor
- Centre Hospitalier Departemental Vendee
Schizophrenia and Related Disorders, Medication Adherence
Embedded Narrative in Interactive Game Design for Improving Medication Adherence of Schizophrenia
This study explores the potential of an interactive narrative game to enhance medication adherence among stable schizophrenia patients.
- Conditions
- Schizophrenia and Related Disorders, Medication Adherence, Mental Health Issue, Gamification
- Trial name
- NCT06175559
- Testing
- Healing Town: Embedded Narrative in Interactive Game (Psycho-education Tool) Design
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Zhu Dian
Family Medicine, Clinical Ultrasound
Analysis of the Results Obtained in the Regular Clinical Practice of a Clinical Ultrasound Classroom For Primary Care Physicians As a Formative Intervention System
The objectives of the project are to evaluate the theoretical-practical knowledge acquired and the degree of satisfaction of a methodology based on theoretical-practical training in abdominal and thyroid clinical ultrasound of…
- Conditions
- Family Medicine, Clinical Ultrasound, Primary Care
- Trial name
- NCT05986110
- Testing
- A training intervention on clinical ultrasound
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundacion para la Investigacion y Formacion en Ciencias de la Salud
Anger, Aggression
The Peace of Mind and Body Project: Treatment Development of Yoga for Anger Management in Incarcerated Adults
The investigators will conduct a pilot randomized clinical trial (n = 40) of hatha yoga vs. a health education group (attention control) for prisoners high in self-reported anger dysregulation.
- Trial name
- POMB (NCT05336123)
- Testing
- Hatha Yoga, Health Education
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Brown University
Breast Cancer
Evaluation of the Impact of a Pharmaceutical Interview on the Adherence to Hormonotherapy in Women With Breast Cancer
Breast cancer is the first cancer in women and 60% of new cases occurring in women 50 to 74 years old. With about 50,000 new cases, it is the second cancer the most serious cancers.
- Trial name
- HORMONOVILLE (NCT04142476)
- Testing
- interview
- Where
- France
- Volunteers
- 105 people
- Sponsor
- Centre Georges Francois Leclerc
Childhood Asthma
Asthma Link Effectiveness Trial
The goal of this cluster Randomized Control Trial is to determine the effectiveness of Asthma Link, a school supervised asthma therapy program, compared with an educational asthma workbook, in improving asthma symptoms for…
- Trial name
- NCT06388460
- Testing
- Asthma Link, Enhanced Usual Care
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- University of Massachusetts, Worcester
Quality of Life
Improving Quality of Life in Nursing Home Residents: A Cluster Randomized Clinical Trial of Efficacy
Improving quality of life (QoL) in residents of nursing homes: A cluster randomized clinical trial of efficacy - The KOSMOS study.
- Trial name
- KOSMOS (NCT02238652)
- Testing
- Communication, Systematic Pain Assessment and Treatment, Medication Review
- Where
- 32 sites in Norway
- Volunteers
- 560 people
- Sponsor
- University of Bergen
Musculoskeletal Pain, School Health
Effectiveness of Health Education Program on Musculoskeletal Pain Management in Primary School Students
Musculoskeletal pain during childhood can negatively affect school attendance, physical activity, and social participation. This study will evaluate the effectiveness of the school-based health education program 'SocLaLola'…
- Conditions
- Musculoskeletal Pain, School Health, Sedentary Behaviors, Health Education
- Trial name
- LOLA (NCT07160478)
- Testing
- School Health Program
- Where
- Spain
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Universitat de Lleida
Multiple Myeloma
A Study to Evaluate Subcutaneous TAK-079 Added to Standard of Care Regimens in Participants With Newly Diagnosed Multiple Myeloma (NDMM)
The purpose of this original study is to determine the recommended phase 2 dose (RP2D) of TAK-079 when administered to participants with NDMM in combination with the backbone treatment regimen.
- Trial name
- NCT03984097
- Testing
- TAK-079, Lenalidomide, Dexamethasone
- Where
- 9 sites in United States
- Volunteers
- 50 people
- Sponsor
- Takeda
Metastatic Prostate Cancer, Therapy, Directly Observed
Cytoreductive Prostatectomy Combined With Triple or Dual Systemic Therapy in mHSPC Patients
To evaluate: The radiographic progression-free survival (rPFS) of metastatic hormone-sensitive prostate cancer (mHSPC) patients treated with androgen deprivation therapy (ADT) + second-generation antiandrogens±chemotherapy…
- Trial name
- NCT06350825
- Testing
- Cytoreductive prostatectomy or brachytherapy, ADT+second-generation antiandrogens ± chemotherapy
- Where
- China
- Volunteers
- 200 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Breast Cancer, Adjuvant Drug Therapy
The POWER Trial: Personalised Dose Optimisation With Adjuvant Tamoxifen Therapy in Breast cancER
In Sweden, approximately 7000 women are diagnosed with hormone-sensitive breast cancer annually. According to international and national guidelines, most of these women are recommended anti-hormonal therapy for five to ten years…
- Trial name
- POWER (NCT07502820)
- Testing
- Individual dose of tamoxifen, Standard adjuvant therapy of tamoxifen
- Where
- 4 sites in Sweden
- Volunteers
- 1,100 people
- Sponsor
- Karolinska Institutet
Respiratory Insufficiency, Pressure Injury
Effectiveness of Platform-Based Lateralization Therapy in Reducing Interface Pressure Between The Patient And The Support Surface
Pressure injury (PI) is characterized as damage to the skin and/or underlying tissues resulting from sustained pressure or a combination of pressure and shear forces between the patient and the support surface.
- Conditions
- Respiratory Insufficiency, Pressure Injury, Intensive Care Medicine, ARDS
- Trial name
- PREVENT-ICU (NCT06819943)
- Testing
- Automated Lateral Rotation Therapy
- Where
- Brazil
- Volunteers
- 25 people
- Sponsor
- University of Sao Paulo General Hospital
Hypertension
SPIRO-First: A Pragmatic Primary Care-Embedded Pilot Trial of Renin-Guided First-Line Antihypertensive Therapy
The goal of this clinical trial is to determine whether a renin-guided antihypertensive treatment strategy is feasible to implement in community primary care clinics and to explore whether spironolactone improves blood pressure…
- Trial name
- SPIRO-First (NCT07687160)
- Testing
- Spironolactone (drug), Candesartan 8mg, Hydrochlorothiazide (HCTZ) 25 milligrams.
- Where
- 4 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Ottawa Hospital Research Institute
HIV/AIDS, Adherence, Medication
Interventions to Improve the HIV PrEP Cascade Among Methamphetamine Users
Despite increasing knowledge about and use of PrEP nationally, HIV continues to have disproportionate impact among cisgender men and transgender persons who have sex with men and transgender persons (MSM/TG), with methamphetamine…
- Conditions
- HIV/AIDS, Adherence, Medication, Drug Use
- Trial name
- NCT03584282
- Testing
- Text Messaging, Peer Navigation
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Washington
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