Clinical trials: Pharyngeal Dysfunction, open to volunteers
Degeneration Spine, Cervical Radiculopathy
Salt Water Gargling on Swallowing Following ACDF
The goal of this randomized control trial is to collect sufficient preliminary data on the efficacy of sodium chloride, hereafter referred to as "saltwater" or "saline" in reducing the difficulty of swallowing following…
- Conditions
- Degeneration Spine, Cervical Radiculopathy, Cervical Stenosis, Cervical Spondylosis
- Trial name
- NCT06475365
- Testing
- Sodium chloride gargle
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Transfer Dysphagia, Oropharyngeal Dysphagia
Onabotulinum Toxin A (Botox) in the Treatment of Pharyngo-esophageal Dysphagia
Dysphagia in patients with stroke, multiple sclerosis, parkinsonism or dystonia can occur due to relative hypertonia of the cricopharyngeus muscle. In the resting state, muscle is contracted and relaxes only during deglutition.
- Conditions
- Transfer Dysphagia, Oropharyngeal Dysphagia, Cricopharyngeus Muscle Dysfunction
- Trial name
- NCT04695600
- Testing
- Botulinum Toxin Type A Injection [Botox]
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Brain Injury, Cognitive Impairment
Somatic and Ear Acupuncture for Dysphagia Rehabilitation and Decannulation After Severe Acquired Brain Injuries
The goal of this interventional, randomized, controlled, double-blind pilot study is to assess the superiority of Acupuncture and Auriculotherapy, in addition to conventional speech therapy rehabilitation, for the treatment of…
- Conditions
- Brain Injury, Cognitive Impairment, Deglutition Disorder
- Trial name
- REDACT (NCT06888219)
- Testing
- Acupuncture and Auricolotherapy, Conventional logopedic rehabilitation
- Where
- Italy
- Volunteers
- 24 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Dysphagia, Stroke
Dysphagia Evaluation After Stroke- Effect Oral Neuromuscular Training on Swallowing Dysfunction
The aim of this study is to investigate the effect of a specific rehabilitation program with an oral device used in stroke patients with persistent oral-and pharyngeal dysphagia.
- Trial name
- DESIRE (NCT02960737)
- Testing
- Oral neuromuscular training using an oral device
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Umeå University
Cognitive Decline, Sarcopenia
Holistic Integration for Healthy Longevity and Aging in Place
Background: Taiwan is experiencing rapid population aging, with a growing prevalence of chronic diseases and functional impairments among older adults.
- Conditions
- Cognitive Decline, Sarcopenia, Depression Disorders, Nutrition Disorder
- Trial name
- HIHOPE (NCT06882434)
- Testing
- Local intervention program, Referral Process, Telehealth Education & Digital Integration
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Olfactory Disorder, Taste Disorders
Prospective Registery of Smell/Taste Clinic Ear/Nose/Throat
Smell/taste disorders are common conditions with a significant impact on quality of life. In September 2021, a specific consultation for patients with smell and taste disorders was initiated at the ENT-HNS (ear, nose, and throat…
- Conditions
- Olfactory Disorder, Taste Disorders, Smell Dysfunction, Smell Disorder
- Trial name
- ProspeRo'Scent (NCT06456008)
- Testing
- Standard of care
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Velopharyngeal Insufficiency, Head and Neck Cancer
Velopharyngeal Dysfunction in Head & Neck Cancer Patients, Pilot Study
Some head and neck cancer survivors develop velopharyngeal dysfunction (VPD), a problem with closure between the soft palate and throat that can cause nasal-sounding speech, food or liquid leaking into the nose, difficulty…
- Conditions
- Velopharyngeal Insufficiency, Head and Neck Cancer, Survivorship, Dysphagia
- Trial name
- NCT07264036
- Testing
- Pharyngeal Wall Augmentation Injection
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Vanessa Torrecillas
GERD
Mechanisms Preventing Pharyngeal Reflux
The overall goal is to define and characterize the manometric characteristics of UES incompetence associated with objectively documented pharyngeal reflux. The investigators will use endoscopic reflux detection as gold standard.
- Trial name
- NCT05696184
- Testing
- Concurrent manometry/impedance/pH with video pharyngo-laryngoscopy, Slow and rapid intra-esophageal infusion
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate
Expiratory Muscle Strength Training for Hypernasal Speech in Children
When the soft palate does not move enough because of a cleft palate or for unknown reasons, this can lead to a speech difference called velopharyngeal insufficiency.
- Conditions
- Velopharyngeal Insufficiency, Velopharyngeal Incompetence Due to Cleft Palate, Inadequate Velopharyngeal Closure, Palatopharyngeal Incompetence
- Trial name
- NCT05492266
- Testing
- Expiratory Muscle Strength Training, Maintenance Training
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Noel Jabbour