Clinical trials: Pharyngitis
Tonsillitis
A Multicenter, Randomized, Double-Blind, Double-Dummy Study Of Azithromycin SR Versus Amoxicillin For The Treatment Of Strep Throat In Children
The objective was to determine if a single 60 mg/kg dose of azithromycin SR was as safe and effective as a 10-day regimen of amoxicillin (45 mg/kg/day, given in divided doses every 12 hours) when used to treat children with strep…
- Trial name
- NCT00643149
- Testing
- amoxicillin, azithromycin SR
- Where
- 46 sites in United States, Canada and 3 more
- Volunteers
- 693 people
- Sponsor
- Pfizer
Sore-throat, Common Cold
A Randomized, Triple-blind, Placebo-controlled Study to Evaluate the Effects of a Throat Spray on the Incidence and Duration of Sickness
This is a randomized, triple-blind, placebo-controlled clinical trial evaluating the effects of Beekeeper's Naturals Propolis Immune Support Throat Spray on the incidence and duration of sickness over a 16-week period.
- Trial name
- NCT07246850
- Testing
- Beekeeper's Propolis Throat Spray
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Beekeeper's Naturals Inc
Pharyngitis, Pain
Ambroxol Spray Sore Throat Study
The development of a new Ambroxol spray formulation for the treatment of sore throat pain associated with acute pharyngitis requires an initial phase II study to be conducted in order to select the most appropriate dose for pain…
- Trial name
- NCT01361802
- Testing
- Ambroxol Spray
- Where
- 15 sites in South Africa
- Volunteers
- 494 people
- Sponsor
- Boehringer Ingelheim
Pharyngitis, Tonsillitis
PASS Study To Evaluate The Potential Of Zithromax To Cause Ocular Problems In Pediatric Patients
This Post-Authorization Safety Study (PASS) is intended to fulfill a regulatory post-marketing requirement to provide data regarding visual abilities in children taking azithromycin (immediate-release formulation) for acute…
- Trial name
- NCT01919996
- Testing
- Azithromycin
- Where
- 6 sites in United States
- Volunteers
- 8 people
- Sponsor
- Pfizer
Upper Resp Tract Infection, Rhinitis Acute
Evaluation of a Hypertonic Seawater Aerosol Therapy Solution in Adults and Children
The purpose of this study is to evaluate the tolerance, the performance and safety of this device, 22‰ Hypertonic seawater aerosol therapy solution in unidose container, to treat adult and peadiatric patients with of upper…
- Conditions
- Upper Resp Tract Infection, Rhinitis Acute, Rhinopharyngitis, Cold Symptom
- Trial name
- AIR (NCT07267689)
- Testing
- Treatment (22‰ Hypertonic seawater aerosol therapy solution)
- Where
- 4 sites in Poland
- Volunteers
- 110 people
- Sponsor
- Laboratoires Gilbert
Sore Throat, Pharyngitis
APC-111 MP Tablet Once a Day vs.Penicillin VK Four Times a Day Both for 10 Days in Patients With Strep Throat
The primary objective of this study is to evaluate the efficacy of APC 111 MP Tablet, 775 mg tablet, given orally (PO)once daily (QD) for 10 days compared to that of Penicillin VK, 250 mg PO four times daily (QID) for 10 days in…
- Conditions
- Sore Throat, Pharyngitis, Tonsillitis
- Trial name
- NCT00242281
- Testing
- APC-111 MP Tablet, 775 mg
- Where
- 41 sites in United States, Canada
- Volunteers
- 600 people
- Sponsor
- Advancis Pharmaceutical Corporation
Pharyngitis
A Comparison Of Valdecoxib 20 Mg Twice Daily and 40 Mg Daily and Placebo In The Treatment Of Sore Throat
The study was performed to evaluate the analgesic efficacy, safety, and tolerability of valdecoxib 20 mg twice daily (BID), valdecoxib 40 mg once daily (QD), and placebo in patients with moderately to severely painful symptomatic…
- Trial name
- NCT00647829
- Testing
- valdecoxib
- Where
- 2 sites in United States
- Volunteers
- 197 people
- Sponsor
- Pfizer
Pharyngitis Bacterial
A Multi-Site Clinical Evaluation of the ARIES Group A Strep Assay in Symptomatic Patients
A multi-center evaluation to assess the diagnostic sensitivity and specificity of the ARIES Group A Strep Assay will be established through a method comparison using prospectively collected, de-identified, clinical samples…
- Trial name
- NCT03037957
- Testing
- ARIES Group A Strep Assay
- Where
- 5 sites in United States
- Volunteers
- 704 people
- Sponsor
- Luminex Corporation
Streptococcus Pyogenes Infection, Pharyngitis
Clinical Performance of the Checkable Medical At-Home Strep A Test
The Checkable Medical At-Home Strep A Test is a rapid chromatographic immunoassay for the qualitative detection of Group A Strep (GAS) antigens from throat swabs.
- Conditions
- Streptococcus Pyogenes Infection, Pharyngitis, Respiratory Tract Infections
- Trial name
- NCT05107362
- Testing
- untrained lay user performs investigational diagnostic test
- Where
- 22 sites in United States
- Volunteers
- 1,347 people
- Sponsor
- Checkable Medical Inc
Pharyngitis
Testing The Effectiveness Of Celecoxib In Patients With Painful Sore Throat
We are proposing a study in which we utilize and augment the sore throat pain model to assess the analgesic effectiveness of celecoxib compared to placebo in patients with painful pharyngitis under randomized, double-blind…
- Trial name
- NCT00402987
- Testing
- Celecoxib
- Where
- United States
- Volunteers
- 269 people
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Recurrent Tonsillitis in Children
A Phase I/II to Assess Safety, Tolerability and Efficacy of DL-lactic Acid Syrup in Children With Recurrent Tonsillitis
The study objectives are to evaluate Tonsitin™ (10% Lactic Acid) safety, tolerability and preliminary efficacy, as a potent treatment for Recurrent Tonsillitis in children.
- Trial name
- NCT01988558
- Testing
- DL - Lactic Acid, Raspberry flavored syrup
- Where
- 3 sites in Israel
- Volunteers
- 51 people
- Sponsor
- Yali Pharmaceuticals
Pharyngitis
Double-blind Trial to Investigate Efficacy and Tolerance of Ambroxol Lozenges 20 mg in Sore Throat
The aim of this trial is to investigate the efficacy and tolerance of Ambroxol lozenges 20 mg in the treatment of sore throat in patients with acute viral pharyngitis.
- Trial name
- NCT00525044
- Testing
- Ambroxol
- Where
- 4 sites in China
- Volunteers
- 249 people
- Sponsor
- Boehringer Ingelheim
Acute Pharyngitis
A Clinical Trial Investigating the Short-term Relief of Symptoms of Acute Pharyngitis by Treatment With Three Different Doses of MYRAMISTIN™ Oromucosal Spray
In this multi-center, randomized, placebo-controlled, double-blind stuy in which patients with acute pharyngitis will receive Myramistin™ / Placebo, which is provided as a spray.
- Trial name
- MIRA1 (NCT04470089)
- Testing
- Myramistin
- Where
- 12 sites in Austria, Germany
- Volunteers
- 170 people
- Sponsor
- Megainpharm GmbH
Pharyngitis
Clinical Trial for Assessment of Safety and Efficacy of a Echinacea/Sage Spray Compared to a Chlorhexidine/Lidocaine Spray in the Treatment of Acute Sore Throats
The aim of the study is to show non-inferiority of an echinacea/sage spray compared to a chlorhexidine/lidocaine-spray in the treatment of acute sore throat during five days of treatment.
- Trial name
- NCT00707902
- Testing
- chlorhexidine/lidocaine, echinacea/sage
- Where
- Switzerland
- Volunteers
- 154 people
- Sponsor
- A. Vogel AG
Streptococcal Sore Throat
In Vitro Diagnostic Device for the Detection of Strep A
The purpose of this trial is to show the accuracy and specificity of the Liat analyzer and assay for detecting Strep A at the point of care lab compared to culture.
- Trial name
- NCT02068469
- Where
- 5 sites in United States
- Volunteers
- 799 people
- Sponsor
- IQuum, Inc.
Infectious Diseases, Healthy Subjects
Effect of the Consumption of a Fermented Milk on Common Infections in Shift-workers
This single-center, randomized, double-blind and controlled study aims to examine the effect of a fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel® = tested product) on the incidence of…
- Conditions
- Infectious Diseases, Healthy Subjects, Respiratory Tract Infections, Sore Throat
- Trial name
- NCT01033799
- Testing
- Fermented dairy product containing the probiotic Lactobacillus casei DN-114 001 (Actimel®), Non fermented dairy product (control)
- Where
- Germany
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Danone Global Research & Innovation Center
Pharyngitis
Safety, Tolerability, and Pharmacokinetic Profile of Grammidin, a Metered Dose Topical Spray in Healthy Volunteers
This study aims to evaluate the safety, tolerability, and pharmacokinetic profile of the Grammidin, a metered dose topical spray, compared to Grammidin lozenges following single administration in healthy volunteers .
- Trial name
- NCT06859281
- Testing
- Grammidin neo, Grammidin, a metered dose topical spray
- Where
- Russia
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Valenta Pharm JSC
Tonsillopharyngitis, Respiratory Tract Infection Viral
Safety and Efficacy of the Sore Throat Lozenges to Treat Acute Sore Throats
Aim of this study is to investigate safety and efficacy of A. Vogel Sore throat lozenges for the treatment of of acute sore throats
- Trial name
- NCT04139681
- Testing
- A. Vogels Sore Throat lozenges
- Where
- Bulgaria
- Volunteers
- 74 people
- Sponsor
- A. Vogel AG
Cough
Safety and Efficacy Reconyl for Cough With/Without Sore Throat
This study is a prospective, randomized, double-blind and placebo-controlled study to find out if reconyl may relieve the acute cough with/without sore throat.
- Trial name
- NCT06510257
- Testing
- Reconyl
- Where
- 2 sites in Indonesia
- Volunteers
- 60 people
- Sponsor
- Dexa Medica Group
Sore Throat, Acute Pharyngitis
Effectiveness and Tolerability of Ectoin® Mouth and Throat Spray Althaea Honey (ERS09)
The aim of this multicentre, actively controlled, randomized, open label, parallel group, prospective, comparator study is to collect data on the clinical effectiveness and tolerability of the medical device ERS09 compared to a…
- Conditions
- Sore Throat, Acute Pharyngitis, Cough
- Trial name
- NCT04203810
- Testing
- Ectoin® Mouth and Throat Spray Althaea Honey (ERS09), EMSER® Hals-und Rachenspray (throat spray)
- Where
- 12 sites in Germany
- Volunteers
- 194 people
- Sponsor
- Bitop AG