Clinical trials: Phobias
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Anxiety, Depression
Attention Bias Modification Training for Young People
Attention bias modification training (ABMT) is a computer-based attention training programme designed to modify the way a person's attention is directed to mild threats in the environment.
- Trial name
- NCT02270671
- Testing
- ABMT
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Social Anxiety Disorder, Social Anxiety
Assessing Mechanisms of Anxiety Reduction in Animal-assisted Interventions
Adolescence and young adulthood is a critical period for the development of social anxiety, which is often linked to other mental health challenges such as depression, mood disorders, and substance abuse.
- Conditions
- Social Anxiety Disorder, Social Anxiety, Social Anxiety Disorder of Childhood
- Trial name
- NCT03249116
- Testing
- animal-assisted intervention, active control
- Where
- United States
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tufts University
Social Anxiety Disorder
Dose Timing of D-Cycloserine to Augment CBT for Social Anxiety Disorder
The purpose of this study is to examine the efficacy of 50 mg of d-cycloserine in comparison to placebo (a pill containing no medication) for improving the effectiveness of cognitive-behavioral therapy (CBT) in reducing symptoms…
- Trial name
- NCT02066792
- Testing
- D-Cycloserine, Cognitive Behavioral Therapy
- Where
- 3 sites in United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- Jasper A. Smits
Social Anxiety Disorder, Performance Anxiety
Acute Anxiolytic Effects of Riluzole on Subjects With Social Anxiety Disorder
The goal of the current proposal is to examine if sublingual riluzole can reduce anxiety in people with social anxiety disorder during a public speaking task.
- Trial name
- NCT03017508
- Testing
- BHV-0223
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Yale University
Cognitive Behavioral Therapy, Autism Spectrum Disorder
Parent-Led Cognitive-Behavioral Teletherapy for Anxiety in Youth With ASD
This study implements an anxiety-focused, parent-led, therapist-assisted cognitive behavioral teletherapy for parents of youth with ASD and anxiety.
- Conditions
- Cognitive Behavioral Therapy, Autism Spectrum Disorder, Anxiety Disorders, Obsessive-Compulsive Disorder
- Trial name
- NCT04111874
- Testing
- Cognitive Behavioral Teletherapy LTA, Cognitive Behavioral Teletherapy STA
- Where
- United States
- Volunteers
- 87 people
- Sponsor
- Baylor College of Medicine
Social Anxiety Disorder
Efficacy of an Attention Guidance VR Intervention for Social Anxiety Disorder
Social anxiety disorder (SAD) is a prevalent mental health concern that impacts approximately 12% of the population. One mechanism thought to maintain SAD is avoidance of faces (i.e. avoidance of negative evaluative threat).
- Trial name
- NCT03683823
- Testing
- Attention guidance, Control intervention
- Where
- United States
- Volunteers
- 21 people
- Sponsor
- University of Texas at Austin
Major Depressive Disorder, Social Anxiety Disorder
Transdiagnostic Brain-Behavior Profiling to Enhance Cognitive Behavioral Therapy Response
Many patients with Major Depressive Disorder (MDD) and generalized Social Anxiety Disorder (gSAD) are treated with cognitive behavioral therapy (CBT) but few have meaningful improvement.
- Trial name
- NCT03175068
- Testing
- CBT, ST
- Where
- United States
- Volunteers
- 203 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Social Anxiety Disorder
The Effects of HD-tDCS on Cognitive Bias Among Individuals With Social Anxiety Symptoms
To examine the offline effects of high-definition tDCS (HD-tDCS) on attention, interpretation and memory biases in youth with social anxiety.
- Trial name
- NCT07099521
- Testing
- Active High-definition transcranial direct current stimulation
- Where
- China
- Volunteers
- 74 people
- Sponsor
- South China Normal University
Alcoholism, Generalized Anxiety Disorder
Levetiracetam for the Treatment of Alcohol Dependence and Anxiety
The purpose of this study is to determine if levetiracetam is effective in treating alcohol dependence in patients with anxiety symptoms.
- Conditions
- Alcoholism, Generalized Anxiety Disorder, Panic Disorder, Social Phobia
- Trial name
- NCT00141115
- Testing
- levetiracetam
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- New York State Psychiatric Institute
Anxiety
Pediatric Anxiety Intervention With an Entertaining Video Game: Feasibility Study
This research study aims to test the feasibility and effectiveness of using an entertaining video game as an addition to traditional therapy for the treatment of anxiety disorders in youth, particularly those youth who may have…
- Trial name
- NCT02713425
- Testing
- Entertaining Video Game
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Social Anxiety Disorder
Efficacy of Virtual Reality Exposure Therapy Scripts for Social Phobia
The purpose of this study is to test the efficacy virtual reality videos to facilitate exposure therapy in social anxiety disorder (SAD). The exposure therapy videos are the focus of this experiment.
- Trial name
- NCT04850989
- Testing
- Pico Goblin VR headset
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Penn State University
Anxiety Disorders
Expectation of Unpleasant Events in Anxiety Disorders
Fear and anxiety are normal responses to a threat. However, anxiety is considered abnormal when the response to the threat is excessive or inappropriate.
- Trial name
- NCT00055224
- Testing
- Threat of shock
- Where
- United States
- Volunteers
- 921 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Social Phobia
Social Phobia Intervention Study of Mannheim
Primary objective: The purpose of this study is to examine efficacy and efficiency of a Stepped Care Program (SCP) for patients with Social Phobia in comparison to the standard cognitive therapy for Social Phobia according to…
- Trial name
- NCT00434759
- Testing
- cognitive therapy, stepped care program based on cognitive therapy
- Where
- Germany
- Volunteers
- 89 people
- Sponsor
- Central Institute of Mental Health, Mannheim
Social Anxiety Disorder, Selective Mutism
Treatment of Social Anxiety Disorder and Selective Mutism
This study is to assess the efficacy of a brief, 11-week, manualized Taming Sneaky Fears for Social Anxiety Disorder (SAD) and/or Selective Mutism (SM) child and parent group Cognitive Behavioural Therapy (CBT) treatment…
- Trial name
- SAD&SMTRMT (NCT02554929)
- Testing
- Taming Sneaky Fears, Parent Psycho-education and Child Socialization
- Where
- Canada
- Volunteers
- 93 people
- Sponsor
- The Hospital for Sick Children
Phobias
The Effect of Intravenous Anesthetics on Fear Learning and Memory
People often develop fearful responses to things, but have no conscious control over the fear. This is a basic form of unconscious memory, called "fear conditioning." Intravenous anesthetic drugs have remarkable effects on…
- Trial name
- NCT00767767
- Testing
- Propofol 0.45mcg/mL, Propofol 0.90mcg/mL, Thiopental 1.5mcg/mL
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Post-traumatic Stress Disorder, Generalized Anxiety Disorder
Primary Care Intervention Strategy for Anxiety Disorders
This study will compare the effectiveness of an intervention strategy for the treatment of people with post traumatic stress disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder in the primary care…
- Conditions
- Post-traumatic Stress Disorder, Generalized Anxiety Disorder, Panic Disorder, Social Anxiety Disorder
- Trial name
- NCT00347269
- Testing
- Cognitive-behavioral therapy, Psychotropic medication optimization, Treatment as Usual
- Where
- 4 sites in United States
- Volunteers
- 1,004 people
- Sponsor
- University of Washington
Social Anxiety Disorder
Adding Cognitive Behavioral Therapy to Drug Treatment for Social Anxiety Disorder
This study will examine whether the addition of cognitive behavioral therapy can improve the efficacy of the medication paroxetine (Paxil®) in treating individuals with social anxiety disorder.
- Trial name
- NCT00074802
- Testing
- Paroxetine, Cognitive behavioral therapy (CBT)
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- Temple University
ANXIETY DISORDERS (or Anxiety and Phobic Neuroses)
Fast-Fail Trials in Mood and Anxiety Spectrum Disorders; Kappa Opioid Receptor Phase 2a
The available treatment for patients with mood and anxiety disorders have significant limitations (Rush, 2007; Denys and de Geus, 2005). There is a need to develop new treatments for people with these disorders.
- Trial name
- FASTMAS_Kor2 (NCT02218736)
- Testing
- CERC-501
- Where
- 6 sites in United States
- Volunteers
- 163 people
- Sponsor
- Duke University
Phobic Disorders
A Safety and Efficacy Study of JNJ-42165279 in Participants With Social Anxiety Disorder
The purpose of this study is to investigate the efficacy of JNJ-42165279 during 12 weeks of treatment in participants with Social Anxiety Disorder (SAD).
- Trial name
- NCT02432703
- Testing
- JNJ-42165279
- Where
- 21 sites in United States, Australia and 1 more
- Volunteers
- 150 people
- Sponsor
- Janssen Research & Development, LLC