Clinical trials: Phobias Spiders
Phobic Disorders
The Role of Treatment Expectation in Exposure Training With Spider Fearful Participants
This study evaluates the role of treatment success expectation in spider fearful individuals on the actual treatment success. Half of participants will have positive treatment success expectations, while the other half will have…
- Trial name
- NCT03012035
- Testing
- positive treatment expectations, neutral treatment expectations
- Where
- Switzerland
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- University Hospital, Basel, Switzerland
Spider Phobia
One-session Treatment for Spider Fears
Despite the efficacy of exposure and response prevention (ERP) for anxiety and phobias, recent theoretical research on fear extinction via inhibitory learning suggests that cognitive restructuring (CR)--the explicit challenging…
- Trial name
- NCT03410264
- Testing
- CR-EXP, EXP-CR, Stress Management
- Where
- United States
- Volunteers
- 51 people
- Sponsor
- University of North Carolina, Chapel Hill
Specific Phobia
Spider Phobia Opposite Action Treatment Study
This study tests the effectiveness of exposure therapy for fear of spiders as enhanced by the use of antagonistic or opposite actions during treatment.
- Trial name
- NCT02905279
- Testing
- Biofeedback Relaxation Training, Exposure Therapy, Exposure with Threat-Relevant Opposite Actions
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Phobic Disorders
Neurophysiological Correlates of Exposition Therapy in Spider Phobia
This study aims to investigate the neurophysiological correlates of spider phobia and its treatment with CBT based Exposure Therapy.
- Trial name
- NCT03653923
- Testing
- Exposure Therapy
- Where
- Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
One Week Follow-up Assessment, Six Weeks Follow-up Assessment
The Effect of Time on Generalization of Exposure-based Benefit
Participants will receive a pre-assessment and an exposure with a control spider. This control spider will be presented again at post-training assessments.
- Conditions
- One Week Follow-up Assessment, Six Weeks Follow-up Assessment, Three Months Follow-up Assessment
- Trial name
- NCT06255821
- Testing
- Exposure
- Where
- Germany
- Volunteers
- 59 people
- Sponsor
- Ruhr University of Bochum
Phobias Snakes, Phobias Spiders
Bringing Exposure Therapy to Real-Life Context With Augmented Reality
In this patented project, U.S. Patent No. 10,839,707, the investigators will develop an augmented reality exposure therapy method for arachnophobia, and fear of snakes, to test in the clinic.
- Trial name
- ARET (NCT03649347)
- Testing
- Augmented reality exposure therapy
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- Wayne State University
Fear of Spiders
The Neural Mechanisms of Imaginal Extinction
Imaginal exposure is a widely used and effective psychological treatment technique in which patients are exposed to fearful stimuli and situations using mental imagery.
- Trial name
- NCT05168592
- Testing
- Threat conditioning, Imaginal extinction
- Where
- Sweden
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Individuals With Fear of Spiders
Neural Activations During Imaginal Exposure in Individuals Fearful of Spiders
This study explores the brain basis of imaginal exposure, a widely used psychological treatment technique. Specifically, this study uses functional magnetic resonance imaging to examine brain areas activated during imaginal…
- Trial name
- NCT03969160
- Testing
- Imaginal exposure
- Where
- 2 sites in Sweden
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Specific Phobia
Effects of Stress on Exposure Therapy
This study investigates whether stress can augment exposure therapy outcome in patients with specific phobia (spider phobia).
- Trial name
- NCT03505437
- Testing
- Cold water condition, Warm water condition
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- Ruhr University of Bochum
Fear of Spiders
Efficacy of a Gamified Augmented Reality Exposure-based Application in Subjects With Fear of Spiders
Investigation of the efficacy of a gamified augmented reality exposure app in individual with fear of spiders.
- Trial name
- GARET2019 (NCT04162509)
- Testing
- AR app
- Where
- Switzerland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Prof. Dominique de Quervain, MD
Posttraumatic Stress Disorder, Anxiety Disorder
Pilot Study of Pharmaceutical and Behavioral Interventions to Treat Anxiety Disorders
The aim of this project is to create fear conditioning paradigm within which the relative strengths of various novel pharmacological and behavioral interventions can be tested.
- Trial name
- NCT01631682
- Testing
- Propranolol, Reactivation, Mifepristone
- Where
- United States
- Volunteers
- 186 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Phobias
fMRI Study Examining Effects of D-cycloserine in Specific Phobia
The research team hopes to use brain imaging and mental testing to learn more about specific phobias and the treatment of phobia.
- Trial name
- NCT00591825
- Testing
- D-cycloserine
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Specific Phobia, Cognitive-behavioral Therapy
Virtual Reality Exposure in Spider Phobia
While knowledge on the neurobiological signatures of fear and anxiety disorders and, in particular, their association with treatment outcome is accumulating, clinical translation still awaits empirical proof of evidence.
- Conditions
- Specific Phobia, Cognitive-behavioral Therapy, Virtual Reality
- Trial name
- NCT03208400
- Testing
- virtual reality exposure
- Where
- 2 sites in Germany
- Volunteers
- 338 people
- Sponsor
- Julius-Maximilians University
Fear of Spiders, Acute Stress Reaction
The Effects of Propranolol and Hydrocortisone on Military-Relevant Performance Outcomes
This clinical trial aims to evaluate the nature and duration of effects of three FDA-approved medications (propranolol and hydrocortisone) on military-relevant cognitive, emotional, and motor performance following an exposure to…
- Trial name
- NCT06982183
- Testing
- Propranolol, Hydrocortisone
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)
Spider Phobia
EMDR in Spider Phobia: Work Mechanisms and Treatment Outcome
The goal of this study is to increase the efficiency of exposure in virtual reality (VR). Based on the EMDR research the investigators would like to show that the implementation of eye movements during the VR exposure results in…
- Trial name
- NCT02973919
- Testing
- Eye Movement Desensitization and Reprocessing Therapy, Virtual Reality Exposure Therapy
- Volunteers
- 53 people
- Sponsor
- University of Regensburg