Clinical trials: Photoaging
Photoaging
The Effects of Zinc Di-(Dibutyryl Lisinate) on Skin Health and the Skin Microbiome in Photoaged Skin
This study is a double-blind randomized vehicle-controlled study assessing how Zinc Di-(dibutyryl lisinate) (Z-DBL) influences skin biophysical measures such as skin hydration, transepidermal water loss, and elasticity, as well…
- Trial name
- NCT06096649
- Testing
- Topical Vehicle + Zinc Di-(dibutyryl lisinate), Topical Vehicle
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Photoaging, Weight Loss
Evaluation of the Effects of a Biostimulator and Dermal Fillers for Cheek Augmentation and Contour Deficiencies
Adult subjects with a history of or currently taking glucagon-like peptide-1 (GLP-1) receptor agonist medication and moderate-to-severe cheek wrinkles and midface contour deficiencies will be treated with Sculptra correction of…
- Conditions
- Photoaging, Weight Loss, Skin Laxity, Photodamaged Skin
- Trial name
- NCT06351358
- Testing
- Sculptra treatment, Restylane Treatment
- Where
- 2 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Anti-aging, Photoaging
A Twelve Week Clinical Study to Evaluate the Efficacy and Tolerability of a Sunscreen Moisturizer SPF 50+
The primary objective of this study is to evaluate the efficacy and tolerance of a moisturizer SPF 50+ when used over a 12-week time period by women with moderate to severe facial photodamage.
- Trial name
- NCT06148558
- Testing
- Sunscreen Moisturizer, Gentle Cleansing Lotion, Facial Moisturizer
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin Diseases, Photoaging
Driving Time and Facial Skin Hydration Asymmetry in Florida Drivers
his observational study examines whether time spent driving is associated with differences in skin hydration between the left and right cheeks in female drivers residing in Florida.
- Conditions
- Skin Diseases, Photoaging, Skin Hydration
- Trial name
- DCHA-FL-25-65 (NCT07764809)
- Testing
- BT-Analyze bioimpedance skin hydration measurement
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- IAS Skin Care
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Radiofrequency Microneedling for Facial Rejuvenation
This randomized, single-center, double-blinded, controlled, clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after radiofrequency microneedling and…
- Trial name
- NCT06157853
- Testing
- Radiofrequency Microneedling, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Facial Photoaging, Deepening of Facial Wrinkles
Regenmedic Cream 2.0 12-week Long-term Clinical Test
The goal of this study is to evaluate the anti-wrinkle, firming, moisturizing and repairing efficacy of a test facial cream after single use and 12 weeks of continuous use via clinical evaluation, instrumental measurement, image…
- Conditions
- Facial Photoaging, Deepening of Facial Wrinkles, Skin Laxity, Decreased Skin Elasticity
- Trial name
- NCT07874113
- Testing
- Test facial cream (topical skin care product)
- Where
- China
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- ChinaNorm
Vascular Lesions, Photoaging
VELOS for the Treatment of Vascular Lesions and Skin Rejuvenation
This is a multi-center, multi-cohort, prospective, open-label study of VELOS for treatment of vascular skin disorders. The plan is to enroll up to 60 subjects from up to 3 centers in the US and worldwide.
- Trial name
- NCT02468453
- Testing
- velos
- Where
- 4 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Syneron Medical
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With a Hybrid-Fractional Laser for Facial Rejuvenation
This randomized, multi-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after hybrid-fractional…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06436261
- Testing
- Hybrid Fractional Laser, Facial Cleanser, Facial Moisturizer
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Skin, Skin Ageing
Clinical Trial to Assess the Efficacy and Safety of a Cosmetic Product in Individuals Showing Signs of Cutaneous Aging.
This clinical study investigates the effects and safety of a topical cosmetic product containing postbiotics (Bifida ferment extract and Pediococcus ferment extract) in women aged 35-60 with visible signs of skin aging.
- Conditions
- Skin, Skin Ageing, Fine Lines, Face Aging/Photo Aging of Moderate Grade
- Trial name
- SkinMeter (NCT07343544)
- Testing
- Active cream
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Wrinkles, Photoaging
Investigation of the Efficacy and Tolerability of a Cosmetic Product With Onabotulinumtoxin A in the Treatment of Facial Lines
This randomized, multi-center, double-blinded, placebo-controlled, split-face clinical trial was conducted to evaluate the procedure-pairing of OnabotulinumtoxinA with a peptide anti-aging serum to improve facial lines and…
- Conditions
- Wrinkles, Photoaging, Fine Lines
- Trial name
- NCT05089851
- Testing
- Onabotulinumtoxin A, Facial Cleanser, Facial Moisturizer
- Where
- 3 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Photoaging, Wrinkle
Evaluating Procedure Pairing of a Post-Procedure Cream Versus a Comparator in Patients Treated With Fractional Ablative CO2 Laser for Facial Rejuvenation
This randomized, single-center, double-blinded, split-face, controlled clinical trial was conducted to investigate the tolerability, safety, and efficacy of a post-procedure cream when used immediately after fractional ablative…
- Conditions
- Photoaging, Wrinkle, Skin Laxity
- Trial name
- NCT06366503
- Testing
- Fractional Ablative CO2 Laser, Facial Cleanser, Facial Moisturizer
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Revision Skincare
Sun Damaged Skin
Photoprotective Effects of a SPF50+ Sunscreen on Skin Genotoxicity Induced by Repeated Chronic Outdoor Sun Exposure
Between 2 and 3 million non-melanoma skin cancers and 132,000 melanoma skin cancers occur globally each year. Sun protection continues to be a major public health issue and has always been a priority research area for Pierre…
- Trial name
- NCT05926791
- Testing
- Cosmetic product
- Where
- France
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Pierre Fabre Dermo Cosmetique
Photoaging, Hyperpigmentation
Randomized, Double-Blind Evaluation of Maple Leaf Extract (Maplifa) for Photoaging
Recent research has reported that the maple leaf extract exhibits anti-aging effects by inhibiting elastase activity, thereby preventing the breakdown of elastin and interfering with the formation of wrinkles.
- Conditions
- Photoaging, Hyperpigmentation, Rhytides
- Trial name
- NCT04586816
- Testing
- 1% red maple leaf extract in cream base, 5% red maple leaf extract, vehicle
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Skin Texture Disorder, Photoaging
Safety and Efficacy Evaluation of the Mosaic Ultra Device
Evaluate the Safety and Efficacy of the Mosaic Ultra 1550nm system for the treatment of skin tone and texture, facial rejuvenation, photoaging, wrinkles, scars, stretch marks, acne vulgaris and hair loss.
- Conditions
- Skin Texture Disorder, Photoaging, Wrinkle, Scar
- Trial name
- NCT06117293
- Testing
- Mosaic
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- CynosureLutronic
Skin Pigment, Photoaging
A Single-Center Open-Label Study of 1064 nm for Nonablative Skin Rejuvenation
The purpose of this investigation is to evaluate the safety and efficacy of the Cutera excel V Laser Genesis procedure utilizing the 1064nm laser for skin rejuvenation.
- Trial name
- NCT03421691
- Testing
- excel V Laser
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Cutera Inc.
Skin Aging, Weight Loss
Effect of Revival Soy on Weight Loss and Skin, Hair, and Nails in Premenopausal Women
The purpose of this study is to determine if dietary consumption of Revival Soy can improve the appearance of the skin, hair, and finger nails and support weight loss in overweight, premenopausal women.
- Trial name
- NCT00352157
- Testing
- Revival Soy Dietary Supplement
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Physicians Pharmaceuticals, Inc.
Photoaging
Double-Blind Study Determining the Efficacy of CannaXR in Decreasing UVA Premutagenic and Photoaging Markers
Ultraviolet light A (UVA) causes oxidization of guanine to mutagenic 8-Oxoguanine (8-OxoG) and the most frequent and best characterized mutation in mitochondrial DNA (mtDNA), a deletion of 4,977 base pairs, called the "common…
- Trial name
- CNXR-001D (NCT05279495)
- Testing
- In a double-blinded fashion, 250 mg CANNAXR cream, Topical VEHICLE cream
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- MINO Labs, LLC
Collagen Degeneration, Wrinkle
The Effects of Topical Almond Oil and Tretinoin on Facial Wrinkles
Investigate the topical use of almond oil, almond oil augmented with 0.5% vitamin E, 0.025% tretinoin oil augmented with castor oil on the appearance of facial fine lines and wrinkles, pigmentation, hydration, trans-epidermal…
- Conditions
- Collagen Degeneration, Wrinkle, Pigmentation, Elastic Skin
- Trial name
- NCT06571721
- Testing
- Topical Product: Almond Oil, Topical Product: Almond oil augmented with 0.5% Vitamin E, Topical Product: 0.025% Tretinoin oil augmented with castor oil
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Integrative Skin Science and Research
Intrinsic Aging of Skin, Skin Wrinkling
Study of Intradermal Injections of RCS-01 in Male and Female Subjects
The primary purpose of this study is to assess the safety profile of RCS-01 injections as compared to placebo injections. This study will also measure the impact these injections will have on skin markers related to aging through…
- Conditions
- Intrinsic Aging of Skin, Skin Wrinkling, Solar Degeneration of Skin
- Trial name
- NCT02391935
- Testing
- RCS-01
- Where
- Germany
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- RepliCel Life Sciences, Inc.
Wrinkle, Photoaging
An Exploratory Investigation of a Novel Skincare Regimen
This trial will assess the effectiveness of the Aria Trio Complete Facial system in being able to reduce blemishes, lines, and wrinkles.
- Conditions
- Wrinkle, Photoaging, Acne, Skin Inflammation
- Trial name
- NCT05517720
- Testing
- Aria Trio complete Facial System
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Trophy Skin