Clinical trials: Photobiomodulation Therapy
Diabetic Foot Ulcer
Low Level Laser Therapy and Expression of VEGF, NO, VEGFR-2, HIF-1α in Diabetic Foot Ulcers
The purpose of this study is to examine the changes of factors including Vascular Endothelial Growth Factor(VEGF), VEGFReceptor-2, Nitric Oxide and hypoxia-inducible factor-1α (HIF-1α), measurements of oxygen saturation in…
- Trial name
- NCT02452086
- Testing
- Low Level Laser(Ga-As)
- Where
- Iran
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Tarbiat Modarres University
Central Serous Chorioretinopathy
Panmacular Versus Minimal Micropulse Laser Therapy in Central Serous Chorioretinopathy
Central serous retinopathy is a disease of poorly understood etiology characterized by accumulation of subretinal fluid and leading to significant decrease in vision.
- Trial name
- NCT04410861
- Testing
- Micropulse laser photostimulation
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Moorfields Eye Hospital Centre Abu Dhabi
Photobiomodulation, Stomatitis, Aphthous
Efficacy of Photobiomodulation in the Treatment and Relief of Pain in Recurrent Aphthous Stomatitis
Photobiomodulation (PBM) is a therapy that stimulates repair, pain relief, and reduces inflammation. The aim of this study is to evaluate the effectiveness of a new PBM protocol in the treatment and pain relief of RAS lesions.
- Trial name
- NCT06416046
- Testing
- Gemini laser
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul
Soft Tissue Injuries
Effect of Photobiomodulation on the Treatment of Soft Tissue Traumatic Injuries
Soft tissue injuries are directly related to the energy of the trauma and its repair is the main factor for bone healing and the recovery of the function of the affected limb.
- Trial name
- NCT04361773
- Testing
- Photobiomodulation
- Volunteers
- 84 people
- Sponsor
- University of Nove de Julho
Burns
Response of Aerobic Capacity to Low Level Laser Therapy in Burned Patients
Severe burns can decrease pulmonary function and impair aerobic capacity persisting for long times post injury. Low level laser therapy is a new modality used to improve aerobic capacity, enhance exercise performance, increase…
- Trial name
- NCT04755296
- Testing
- Low level laser therapy, Aerobic exercises, Traditional physical therapy program
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Osgood-Schlatter Disease, Sever's Disease
Low-Level Laser Therapy for Osgood-Schlatter or Sever Pain in Youth Athletes
The goal of this clinical trial is to learn if low-level laser therapy (also called photobiomodulation) works to treat knee or heel pain in physically active children and adolescents with Osgood-Schlatter disease or Sever…
- Trial name
- NCT07446517
- Testing
- Photobiomodulation (Low-Level Laser Therapy)
- Where
- Poland
- Volunteers
- 36 people
- Sponsor
- Medical University of Gdansk
Dental Malocclusion
Evaluation of the Effect of Corticotomy and Low Level Laser Therapy on Orthodontic Tooth Movement
The aim of the present study was to compare, a standard efficient technique in accelerating OTM as surgical corticotomy as a gold standard versus surgical corticotomy combined with LLLT in an attempt for further acceleration of…
- Trial name
- NCT03906084
- Testing
- Corticotomy and low laser therapy, Corticotomy facilitated Orthodontics
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Cairo University
Male Pattern Baldness, Female Pattern Baldness
Low Level Light Therapy (LLLT) for Hair Growth
A total of 62 participants will receive red light (660 nm) to the scalp through a specially designed light therapy device integrated into a conventional hat.
- Trial name
- NCT03938948
- Testing
- low-level laser/light therapy
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Awareable Technologies Inc
Lateral Ankle Sprain, Ankle Sprain 1St Degree
Therapeutic Low Laser Therapy and Kinesio Taping for Lateral Ankle Sprain
HYPOTHESIS Null Hypothesis (H0): There is no significant effect of therapeutic low laser therapy and kinesio taping in patients with grade 1 \& 2 lateral ankle sprain.
- Conditions
- Lateral Ankle Sprain, Ankle Sprain 1St Degree, Ankle Sprain 2Nd Degree
- Trial name
- NCT07235943
- Testing
- Using Low-Level Laser Therapy, Combined: Low Laser Therapy with Kinesio Taping
- Where
- Pakistan
- Volunteers
- 62 people
- Sponsor
- University of Lahore
Scar, Laser Therapy
Treatment of Surgical Scars Using the Pulsed Dye Laser
The purpose of this study is to determine whether treatment of fresh surgical scars with a pulsed dye laser using purpura-inducing settings will improve clinical appearance better than one using non-purpura-inducing settings or…
- Trial name
- NCT00970671
- Testing
- Laser treatment with Purpuric settings, Laser treatment with Nonpurpuric settings, No treatment
- Where
- United States
- Volunteers
- 28 people
- Sponsor
- University of California, San Diego
Photobiomodulation, Dental Hypersensitivity
Evaluation of Tooth Sensitivity After Scaling and Root Planing Treated With Photobiomodulation
One hundred twenty patients with dentin sensibility after non-surgical scaling and root planning (SRP) will be randomly included in 2 groups: Experimental Group: SRP+ Photobiomodulation (PBM) (660nm, 100W, area 0,5cm2, 200w/cm2…
- Trial name
- NCT05946265
- Testing
- Photobiomodulation, simulation of Photobiomodulation
- Where
- Brazil
- Volunteers
- 112 people
- Sponsor
- University of Nove de Julho
Retinopathy of Prematurity (ROP)
Rainbow Extension Study
The purpose of this study was to evaluate the long term efficacy and safety of intravitreal ranibizumab compared with laser ablation therapy in patients who were treated for retinopathy of prematurity (ROP) in the core study…
- Trial name
- RainbowExt (NCT02640664)
- Testing
- Ranibizumab
- Where
- 73 sites in United States, Austria and 22 more
- Volunteers
- 180 people
- Sponsor
- Novartis Pharmaceuticals
Neoplasms
Immunostimulating Interstitial Laser Thermotherapy in Solid Cancers
Thermotherapy is a technology aiming at destroying tissue, for example tumor tissue. Immunostimulating Interstitial Laser Thermotherapy (imILT) is a specific form of thermotherapy, which, in addition to destroying tumor tissue…
- Trial name
- NCT02690428
- Testing
- Immunostimulating Interstitial Laser Thermotherapy
- Where
- Germany
- Volunteers
- 3 people
- Sponsor
- Clinical Laserthermia Systems AB
Myofacial Pain Syndrome
The Effect of Low Level Laser Therapy (LLLT) in Myofacial Pain Syndrome
Temporomandibular disorders (TMDs) are the major cause of non-dental pain in orofacial area. Laser therapy can be considered as one of the most recent treatment approaches in the field of physiotherapy.
- Trial name
- NCT01417637
- Testing
- Low level laser therapy
- Where
- Iran
- Volunteers
- 20 people
- Sponsor
- Mashhad University of Medical Sciences
Cervicalgia
Pompage and Photobiomodulation on Pain, Range of Motion, and Quality of Life in Patients With Neck Pain
The aim of this study is to evaluate the effects of Pompage associated or not with PBM, using a cluster of LEDs, on pain and neck disability.
- Trial name
- NCT06416527
- Testing
- Photobiomodulation (Experimental), Pompage Technique (manual therapy)
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Dentin Hypersensitivity
Grape Seed Extract VS Low Level Laser Therapy for Dentin Hypersensitivity
Dentin hypersensitivity (DH) is a common clinical problem frequently seen in dental patients. According to Splieth et al., the prevalence of dentin hypersensitivity is 3-98% in adult population.DH is described as a short, sharp…
- Trial name
- NCT05927831
- Testing
- Grape Seed Extract, Low-level laser therapy
- Where
- Malaysia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Manipal University College Malaysia
Acne Vulgaris
Non-cutting Laser Therapy in the Treatment of Acne
The purpose of this research project is to study the effect of non-ablative (non-cutting) laser therapy, a technique that uses laser energy to try to improve the appearance of the skin.
- Trial name
- NCT00113425
- Testing
- V-Beam laser, Candela Corp., 595 nm wavelength
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- University of Michigan
Macula Edema, Retinal Vein Occlusion
Near-Infrared Light Photobiomodulation Treatment for Retinal Vein Occlusion Macular Oedema
This pilot study aims to establish that treatment with near infrared light (NIR) reduces cystic macular oedema in patients with a retinal vein occlusion.
- Trial name
- NIRVO (NCT04847869)
- Testing
- Ellex Integre NIR laser
- Where
- Australia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Sydney
Retinitis Pigmentosa (RP)
Subthreshold Micropulse Laser Therapy (SML) in Retinitis Pigmentosa
Introduction Retinitis pigmentosa (RP) is the most common form of genetic retinal degenerative disease. The disease is progressive and leads to blindness and permanent disability within a few years of diagnosis.
- Trial name
- NCT07088705
- Testing
- SML 577 nm, SML 810 nm
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Marta P. Wiącek
Plantar Fascitis, Achilles Tendon Pain
Effect of HILT vs LLLT in Treatment of Patients With Achilles Tendinitis or Plantar Fasciitis
The aim of this study is to evaluate and compare the changes of heel pain, functional health and well-being after high-intensity and low-level laser therapy for plantar fasciitis or Achilles tendinopathy
- Trial name
- NCT03873961
- Testing
- High-intensity laser therapy, Low-level Laser therapy
- Where
- Lithuania
- Volunteers
- 155 people
- Sponsor
- Lithuanian University of Health Sciences