Clinical trials: Photon Radiotherapy
Benign Meningioma
Proton/Photon Rt - Benign Meningiomas(P92-13)
The purpose of this study is to determine the best radiation dose for participants with meningioma that has grown back after previous surgery, or which the surgeon has been unable to remove completely.
- Trial name
- NCT02947984
- Testing
- Standard Treatment, Higher Dose
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Massachusetts General Hospital
Lung Neoplasms
Concurrent Chemoradiotherapy Using Intensity Modulated Radiotherapy (IMRT) & Docetaxel-cisplatin (or Carboplatin) Followed by Adjuvant Chemotherapy for Inoperable Stage III Non-small-cell Lung Cancer
Primary Objective: Response rate (by contrast CT scan) Secondary Objectives: Progression-free survival (PFS) Overall survival (OS)
- Trial name
- C-CRISP (NCT01266512)
- Testing
- DOCETAXEL, Intensity Modulated Radiotherapy (IMRT), CISPLATIN
- Where
- Hong Kong
- Volunteers
- 34 people
- Sponsor
- Sanofi
Head and Neck Cancers - Nasopharyngeal
Photon Therapy Face Mask on Dermatitis Post Head and Neck Radiotherapy
A randomized controlled trial (RCT), 60 HNC patients who underwent radiotherapy (RT) with or without chemotherapy represented the sample of the study.
- Trial name
- dermatitis (NCT05855265)
- Testing
- photon therapy face mask
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Khadra Mohamed Ali
Breast Cancer, Lymphedema
Single-Photon Emission Computed Tomography, Computed Tomography Lymphoscintigraphy, and Intensity-Modulated Radiation Therapy in Treating Patients Who Have Undergone Surgery for Stage I or Stage II Breast Cancer
RATIONALE: Diagnostic procedures, such as single-photon emission computed tomography and computed tomography lymphoscintigraphy, may help lower the dose of radiation therapy after surgery, and help prevent lymphedema.
- Trial name
- NCT00743314
- Testing
- screening questionnaire administration, computed tomography, lymphoscintigraphy
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mayo Clinic
Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma
Photon Craniospinal Irradiation for the Treatment of Leptomeningeal Disease Secondary to Breast Cancer or Non-small Cell Lung Cancer
This phase II trial tests how well craniospinal irradiation (CSI) using photon volumetric modulated arc radiotherapy (VMAT) works in treating patients with breast cancer or non-small cell lung cancer (NSCLC) that has spread from…
- Conditions
- Anatomic Stage IV Breast Cancer AJCC v8, Metastatic Breast Carcinoma, Metastatic Lung Non-Small Cell Carcinoma, Metastatic Malignant Neoplasm in the Leptomeninges
- Trial name
- NCT06910761
- Testing
- Biospecimen Collection, Craniospinal Irradiation, Electronic Health Record Review
- Where
- 2 sites in United States
- Volunteers
- 35 people
- Sponsor
- City of Hope Medical Center
Prostate Cancer
Preference-based Comparative Study on Definitive Radiotherapy of Prostate Cancer With Protons
ProtoChoice-P is a prospective multicenter trial to evaluate proton therapy in patients suffering from prostate cancer. Primary aim of the study is a decrease of moderate or severe genito-urinary or intestinal side effects…
- Trial name
- ProtoChoiceP (NCT02766686)
- Testing
- Radiotherapy with protons, Radiotherapy with photons
- Where
- 3 sites in Germany
- Volunteers
- 180 people
- Sponsor
- Technische Universität Dresden
Brain Tumors
Comparison of Proton and Photon Radiotherapy of Brain Tumors (ProtoChoice-Hirn)
This protocol compares the toxicity of radiotherapy or radiochemotherapy applied with different radiation modalities - protons or photons.
- Trial name
- NCT02824731
- Testing
- Radiation with protons, Radiation with photons
- Where
- 2 sites in Germany
- Volunteers
- 555 people
- Sponsor
- Technische Universität Dresden
NSCLC
Photon Versus Particle Therapy for Recurrent Lung Cancer; a Planning Study Based on a Reference Dataset of Patients.
Patients with lung cancer may develop a second primary tumor or recurrent disease after previous radiotherapy. Surgical salvage therapy is the mainstay of therapeutic options.
- Trial name
- NCT02029222
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Maastricht Radiation Oncology
Melanoma (Skin), Melanoma Stage IV
Targeted Imaging of Melanoma for Alpha-Particle Radiotherapy
The study hypothesis is that new imaging agents [203Pb]VMT01 and [68Ga]VMT02 can be safely used in humans without independent biological effect and can be used to image melanoma tumors expressing the melanocortin sub-type 1…
- Conditions
- Melanoma (Skin), Melanoma Stage IV, Melanoma, Uveal, Melanoma, Mucosal
- Trial name
- TIMAR1 (NCT04904120)
- Testing
- [203Pb]VMT01, [68Ga]VMT02
- Where
- United States
- Volunteers
- 7 people
- Sponsor
- Perspective Therapeutics
Pancreatic Cancer
Neoadjuvant Accelerated Short Course Radiation Therapy With Photons and Capecitabine for Resectable Pancreatic Cancer
The purpose of this research study is to determine if it is possible to deliver high dose radiation in one week while also giving the drug capecitabine for the treatment of pancreatic cancer prior to surgery, to determine if this…
- Trial name
- NCT00889187
- Testing
- Neoadjuvant Short-Course Photon Radiation, Capecitabine
- Where
- 3 sites in United States
- Volunteers
- 10 people
- Sponsor
- Dana-Farber Cancer Institute
Breast Cancer
A Study of Accelerated 3 Fraction Photon,Proton or Brachytherapy for Early Invasive and Noninvasive Breast Ca
This is an open label phase II study to determine the safety and efficacy of a novel 3 fraction daily dosing regimen for accelerated partial breast irradiation (APBI) for early invasive and noninvasive breast cancer.
- Trial name
- NCT02453737
- Testing
- Brachytherapy APBI, 3D-CRT (photon) APBI, Proton APBI
- Where
- 3 sites in United States
- Volunteers
- 170 people
- Sponsor
- Mayo Clinic
Prostate Cancer
Quality of Life Study for Prostate Cancer Patients
The goal of this behavioral research study is to look at patients' quality of life after treatment or management for prostate cancer.
- Trial name
- NCT00561444
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 1,051 people
- Sponsor
- M.D. Anderson Cancer Center
Coronary Artery Disease
Image Quality and Radiation Dose Associated With Cardiac Scans in Modern CT Scanners
The main objective of this study is to evaluate the dose efficiency of coronary CT angiography (CTA) using a photon counting detector CT (PCD-CT) with the dose efficiency of coronary CT angiography of prior CT generations.
- Trial name
- NCT05245149
- Testing
- Cardiac CTA on a photon-counting detector CT (PCD-CT), Cardiac CTA on a regular CT with Energy-Integrating Detector (EID-CT)
- Volunteers
- 200 people
- Sponsor
- University Hospital Augsburg