Clinical trials: Photosensitizing Agents
Actinic Keratosis
Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Face and Scalp
This Phase 3, randomized, multi-center, evaluator-blind, vehicle-controlled study evaluates the efficacy and safety of reformulated Levulan Kerastick (aminolevulinic acid HCl 20%) combined with photodynamic therapy (PDT) for…
- Trial name
- NCT07144345
- Testing
- Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle containing excipients only (VEH) without active ingredient, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E
- Where
- 10 sites in United States
- Volunteers
- 160 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Sunscreening Agents
18348-Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02823483
- Testing
- Sunscreen Lotion (BAY987521), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Healthy
Evaluation of Photosafety of BI 730357 Compared to Placebo and the Known Photosensitizing Agent Ciprofloxacin
To evaluate the photosensitivity potential of BI 730357
- Trial name
- NCT04147260
- Testing
- BI 730357, Ciprofloxacin
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02754102
- Testing
- Sunscreen Spray- Liquid (BAY987516)
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Keratoconus, Corneal Diseases
Collagen Cross-Linking With Ultraviolet-A in Asymmetric Corneas
This study will assess changes in visual acuity and corneal symmetry after corneal collagen cross-linking (CXL) of asymmetric corneas.
- Conditions
- Keratoconus, Corneal Diseases, Eye Diseases, Photosensitizing Agents
- Trial name
- NCT03029104
- Testing
- CXLO Corneal Strengthening Solution and UVA Illumination Device
- Where
- 9 sites in United States
- Volunteers
- 2,228 people
- Sponsor
- Cxlusa
Actinic Keratosis, Keratosis, Actinic
Study to Evaluate Safety and Tolerability of BF-200 ALA (Ameluz®) for Photodynamic Therapy in the Treatment of the Expanded Field of Actinic Keratosis on Face and Scalp
The aim of the study is to evaluate the safety and tolerability of PDT for treatment of mild to severe actinic keratosis on the face and scalp in the expanded treatment field using 3 tubes of BF-200 ALA 10% gel (Ameluz®) in…
- Conditions
- Actinic Keratosis, Keratosis, Actinic, Keratosis
- Trial name
- NCT05060237
- Testing
- BF-200 ALA and red light LED lamp
- Where
- 9 sites in United States
- Volunteers
- 112 people
- Sponsor
- Biofrontera Bioscience GmbH
Sunscreening Agents
18794 - Human Photo Toxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02751372
- Testing
- BAY 987517, Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Sunscreening Agents
Human Phototoxicity Test (823/2016)
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02962856
- Testing
- BAY987517, Untreated Skin
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Bayer
Breast Cancer
A Novel Therapy for the Treatment of Chest Wall Progression of Breast Cancer
This study will assess safety and ergonomics/engineering design of a novel cancer treatment, Continuous Low Irradiance Photodynamic therapy (CLIPT).
- Trial name
- NCT01262716
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Rogers Sciences Inc.
Actinic Keratosis
Study of Reformulated Levulan Kerastick Plus PDT for Actinic Keratosis on Upper Extremities
This Phase 3, randomized, multi-center, evaluator-blind, vehicle-controlled study evaluates the efficacy and safety of reformulated Levulan Kerastick (aminolevulinic acid HCl 20%) combined with photodynamic therapy (PDT) for…
- Trial name
- NCT07144852
- Testing
- Reformulated Levulan Kerastick containing aminolevulinic acid hydrochloride (ALA HCl), 20%, Vehicle, Blue Light Photodynamic Therapy Illuminator device, BLU-U® model 4170E.
- Where
- 20 sites in United States
- Volunteers
- 260 people
- Sponsor
- Sun Pharmaceutical Industries, Inc.
Actinic Keratoses
Study to Evaluate the Safety, Tolerability and Efficacy of BF-200 ALA (Ameluz®) in the Field-directed Treatment of Actinic Keratosis (AK) on the Extremities and Neck/Trunk With Photodynamic Therapy (PDT) Using a RhodoLED Lamp
The aim of this study is to test the safety, tolerability and efficacy of field-directed photodynamic therapy (PDT) with 10% aminolevulinic acid gel (Ameluz®, BF-200 ALA) in combination with one of the narrow spectrum red light…
- Trial name
- NCT05662202
- Testing
- BF-200 ALA and red light LED lamp, Vehicle and red light LED lamp
- Where
- 14 sites in United States
- Volunteers
- 172 people
- Sponsor
- Biofrontera Inc.
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02751489
- Testing
- Bain De Soliel - Solid
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Keratoconus
Cyanocobalamin as Photosensitizing Agent
is cyanocobalamin active as Photosensitizing Agent instead of riboflavin ? using cyanocobalamin with mix of external collagen to make crosslinking with cornea collagen to make rigid of cornea
- Trial name
- NCT05395650
- Volunteers
- 1 people
- Sponsor
- EL Romany Ophthalmics Factory
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects
- Trial name
- NCT02750475
- Testing
- Sunscreen Sport Lotion (BAY987516), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Sunscreening Agents
Human Phototoxicity Test
To determine the phototoxic potential of a topically applied article in human subjects.
- Trial name
- NCT02751541
- Testing
- Sunscreen Sport Spray (BAY987519), Untreated Skin
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Bayer
Sunscreen Agents
Test the Phototoxicity of Sunscreen Products
The primary objective of this study was to evaluate the potential for phototoxicity of the sun care products SPF 50 Y65 110, SPF 50 Y51 002, and SPF 15 V27 104 compared to that of a negative control (0.9% sodium chloride [NaCl])…
- Trial name
- NCT02802930
- Testing
- SPF 50 Y65 110 (BAY987519), SPF 50 Y51 002 (BAY987519), SPF 15 V27 104 (BAY987519)
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bayer