Clinical trials: Phototherapy Complication
Cancer
Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain
This is a phase III, randomized, double-blind, placebo-controlled, multicenter study of the clinical response to fentanyl sublingual spray as a treatment for breakthrough cancer pain.
- Trial name
- NCT00538850
- Testing
- Fentanyl sublingual spray
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- INSYS Therapeutics Inc
Diabetic Retinopathy
Photobiomodulation for the Treatment of Diabetic Macular Edema
The current application proposes to conduct a prospective, clinical trial in diabetic subjects with diabetic macular edema (DME) to evaluate the therapeutic efficacy of 670 nm photobiomodulation on validated clinical outcome…
- Trial name
- PTDME (NCT02457975)
- Testing
- 670nm PBM, intravitreous VEGF-inhibitors
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Medical College of Wisconsin
Premature Birth
Parenteral Nutrition Light Protection and Premature Outcomes
Investigators propose a prospective study to investigate the effect of full light protection of the PN on cholestasis and other oxidative stress associated diseases in premature infants when they receive PN for more than one…
- Trial name
- NCT04525872
- Testing
- Full parenteral nutrition light protection of the bag, tubing and lipids
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- NYU Langone Health
Phototherapy Complication
Investigation of Vitamin Levels During Phototherapy
Research project in which blood samples of patients undergoing UVB phototherapy for the treatment of different cutaneous diseases will be investigated for changes of folate levels and further vitamins over the course of treatment.
- Trial name
- NCT03246308
- Testing
- Phototherapy
- Where
- Austria
- Volunteers
- 100 people
- Sponsor
- Medical University of Vienna
Out-of-hospital Cardiac Arrest (OHCA), Post-Cardiac Arrest Syndrome
Pulse Pressure and Outcomes After Out-of-Hospital Cardiac Arrest
STEP-PRESS is a predefined exploratory observational substudy nested within the STEPCARE trial. The study will evaluate whether early low pulse-pressure burden after out-of-hospital cardiac arrest is associated with early…
- Trial name
- STEP-PRESS (NCT07586878)
- Where
- Sweden
- Volunteers
- 3,500 people
- Sponsor
- Region Skane
Renal Cell Carcinoma
The Pharmacological Effects of Using Cabozantinib With a Light Breakfast
Cabozantinib is a drug which is used to treat metastasized kidney cancer. While it works well, it has a lot of side effects and is quite expensive (€213,- every tablet, €6403,- every month).
- Trial name
- Skippy 1 (NCT05263245)
- Testing
- Light breakfast
- Where
- 2 sites in Netherlands
- Volunteers
- 12 people
- Sponsor
- dr. Tom van der Hulle
Bladder Cancer
Longer-term Recurrence Rates in Patients With Bladder Cancer After Hexvix (Cysview)Fluorescence Cystoscopy/TURB
The study is intended to investigate whether the improved initial detection and resection of bladder cancer lesions in patients with non-muscle invasive bladder cancer with Hexvix (Cysview) fluorescence cystoscopy/TURB will lead…
- Trial name
- NCT01166230
- Where
- 24 sites in United States, Austria and 3 more
- Volunteers
- 551 people
- Sponsor
- Photocure
Diabetic Foot Ulcer
Blue Light Photobiomodulation Therapy on Neuroischemic Patients
This is a pilot case/control clinical study on a group of outpatients with diabetic foot lesions aiming to verify the efficacy and safety of the Blue light photobiomodulation therapy with EmoLED medical device, in addition to…
- Trial name
- HERMES (NCT04831606)
- Testing
- debridement, Offloading, Advanced dressing
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Emoled
Diabetic Foot Ulcers
Monochromatic Phototherapy on Diabetic Foot Ulcers
The purpose of this study is to evaluate the efficacy and safety of monochromatic phototherapy (Biolight®) on foot ulcers in diabetic patients, in comparison of placebo phototherapy as a complementary to standard diabetic foot…
- Trial name
- NCT00859599
- Testing
- Monochromatic phototherapy, Biolight®, Monochromatic phototherapy
- Where
- 7 sites in Sweden
- Volunteers
- 107 people
- Sponsor
- Biolight AB
Head and Neck Neoplasms, Radiodermatitis
Determinants of Radiation Dermatitis in Head and Neck Cancer Patients Receiving Preventive Photobiomodulation
The goal of this observational study is to identify factors associated with the occurrence of grade 2 or higher radiation dermatitis in adults with head and neck cancer treated with radiotherapy who receive preventive…
- Trial name
- COH-PBM-3J (NCT07899866)
- Testing
- Preventive photobiomodulation, External beam radiotherapy, Functional, quality-of-life and photographic assessments
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Hopital Forcilles
Postoperative Delirium
Association of Plasma Biomarkers for Neurological Injury and Postoperative Delirium After Cardiac Surgery
Delirium is one of the most common complications after cardiac surgeries, incidence of which is 20~70%. Causes and pathophysiology of delirium has not been elucidated yet, however, inflammatory response of the nervous system…
- Trial name
- NCT04194411
- Where
- South Korea
- Volunteers
- 152 people
- Sponsor
- Yonsei University
Kidney Cancers
Photodynamic Diagnosis of Kidney Cancer Using Fluorescence Endoscopy and Oral 5-ALA
The goal of this prospective, single-arm feasibility study is to evaluate the safety and feasibility of using Gleolan® (5-aminolevulinic acid), an FDA-approved drug currently used during brain tumor surgery, in adults with…
- Trial name
- NCT07828704
- Testing
- 5-Aminolevulinic acid Hydrochloride (Gliolan®)
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Henry Ford Health System
Bladder Cancer
Effectiveness of Hexaminolevulinate (Hexvix) in the Diagnosis and Treatment of Patients With Non-invasive Bladder Cancer
The purpose of this study is to determine the effectiveness of hexaminolevulinate (Hexvix) in the diagnosis and treatment of patients with non-invasive bladder cancer and if it results in a change in patient management.
- Trial name
- NCT00634621
- Testing
- Hexaminolevulinate (Hexvix)
- Where
- Spain
- Volunteers
- 283 people
- Sponsor
- GE Healthcare
Orthodontic Appliance Complication, Plaque, Dental
Regular Home Use of Dual-light Photodynamic Therapy on Oral Health in Adolescents Undergoing Fixed Orthodontic Treatment
This study is designed to determine the efficacy of the Lumoral method on oral health in adolescents undergoing fixed orthodontic treatment.
- Conditions
- Orthodontic Appliance Complication, Plaque, Dental, Gingival Inflammation
- Trial name
- NCT05825742
- Testing
- Lumoral Treatment, Standard oral health instructions
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Koite Health Oy
Bladder Tumor
Endoscopic Resection of Bladder Tumors
To confirm the benefit of endoscopic resection under fluorescence and blue light of high grade non-muscle invasive bladder tumor, and verifying if the second endoscopic resection recommended nowadays can be deleted.
- Trial name
- NCT01750970
- Testing
- Endoscopic resection under blue light (Hexvix®)
- Where
- France
- Volunteers
- 68 people
- Sponsor
- Hopital Foch
Bladder Urothelial Carcinoma, TURBT
Storz Professional Image Enhancement System Versus White Light Imaging Assisted TURBT for Treatment of NMIBC
Compare the therapeutic utility of SPIES assisted TURB with WLI assisted TURB in patients with non-muscle invasive bladder cancer.
- Conditions
- Bladder Urothelial Carcinoma, TURBT, Bladder Neoplasm, Cystoscopy
- Trial name
- NCT03138824
- Testing
- SPIES assisted TURBT, WLI assisted TURBT
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Mansoura University
Cancer
Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant
RATIONALE: Antifungals, such as caspofungin acetate, may be effective in treating fungal infections caused by chemotherapy or stem cell transplant.
- Trial name
- NCT00110045
- Testing
- caspofungin acetate
- Where
- 13 sites in Belgium, France and 5 more
- Volunteers
- 171 people
- Sponsor
- European Organisation for Research and Treatment of Cancer - EORTC
Surgery, Nasal Disease
Assessing the Efficacy of Photodynamic Therapy for Preventing Surgical Site Infections
This is a randomised, unblinded interventional device proof of concept pilot trial in which patients undergoing nasal surgery will be selected for either photodisinfection therapy (PDT) with the Steriwave™ ND System, or control…
- Conditions
- Surgery, Nasal Disease, Light; Therapy, Complications
- Trial name
- LIGHT (NCT06731881)
- Testing
- Nasal PDT, Photosensitizer formulation only, Standard follow-up
- Where
- United Kingdom
- Volunteers
- 80 people
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Bladder Carcinoma, Genitourinary System Neoplasm
Light Therapy and Occupational Therapy Fatigue Management-Based Intervention for Patients With Genitourinary Cancers
This clinical trial evaluates light therapy and occupational therapy in improving cancer related fatigue (CRF) patients with genitourinary cancers.
- Conditions
- Bladder Carcinoma, Genitourinary System Neoplasm, Kidney Carcinoma, Prostate Carcinoma
- Trial name
- NCT05519878
- Testing
- Best Practice, Bright White Light Therapy, Occupational Therapy
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- City of Hope Medical Center
Development and Health, Nutrition
Effects of Light Exposure for Postpartum Depression on Infant Development
About 11% of women develop depression and anxiety after giving birth. These symptoms can reduce a mother's quality of life and daily functioning and may negatively affect her child's growth and development.
- Trial name
- Chrono_Baby (NCT07440355)
- Where
- Brazil
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital de Clinicas de Porto Alegre