Clinical trials: Phototherapy Complication
Bladder Cancer
Comparison Study of Narrow Band Imaging Versus White Light Resection in Patients With Bladder Tumors/Cancer
The purpose of this study is to compare the recurrence rate at 1 year following Narrow Band Imaging and trans-urethral resection of bladder tumor with White Light and TURB in patients with non-muscle invasive bladder cancer.
- Trial name
- NCT01180478
- Testing
- White Light, Narrow Band Imaging
- Volunteers
- 965 people
- Sponsor
- Clinical Research Office of the Endourological Society
Cancer
Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment
RATIONALE: Caspofungin acetate or amphotericin B liposomal may be effective in preventing or controlling fever and neutropenia caused by chemotherapy, bone marrow transplantation, or peripheral stem cell transplantation.
- Trial name
- NCT00008359
- Testing
- caspofungin acetate, liposomal amphotericin B
- Where
- United States
- Sponsor
- Memorial Sloan Kettering Cancer Center
Diabetic Foot, Diabetic Foot Ulcer
Adjunctive Phototherapy Treatment of Infected Diabetic Ulcers
The key purpose of this study is to determine and understand the safety and effectiveness of blue light phototherapy in the treatment and healing of infected diabetic wounds, as well as determining if this treatment is capable of…
- Conditions
- Diabetic Foot, Diabetic Foot Ulcer, Diabetes, Diabetes Mellitus
- Trial name
- NCT04285710
- Testing
- Phototherapy, Debridement Surgery and Wound Dressing
- Where
- United States
- Sponsor
- Boston Medical Center
Myopia, Light; Therapy, Complications
Optimizing Light Exposure for Myopia Prevention and Control (LightSPAN)
The goal of this clinical trial is to evaluate whether the optimization of daily exposure to light in primary school children can lead to better myopia prevention and control.
- Conditions
- Myopia, Light; Therapy, Complications, Myopia Progression, Short-Sighted
- Trial name
- LightSPAN (NCT06631339)
- Testing
- Light Intervention, Digital Intervention, Control Group
- Where
- 5 sites in Singapore
- Volunteers
- 396 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Intraoperative Arterial Hypotension
Association of Intraoperative Blood Pressure Excursions Below Cerebral Autoregulatory Boundaries With Organ Injury Following Major Noncardiac Surgery
The aim of study is to investigate the clinical relevance of blood pressure (BP) excursions below cerebral autoregulatory boundaries in major noncardiac surgery.
- Trial name
- AR-NONCARDIAC (NCT05336864)
- Testing
- Non-invasive cerebral oximetry monitoring, additional perioperative blood sampling, clinical & telephone assessments
- Where
- 3 sites in Switzerland
- Volunteers
- 650 people
- Sponsor
- University Hospital, Basel, Switzerland
Hyper Bilirubinemia, Premature Infant
Cycled Phototherapy
Cycled phototherapy (PT) is likely to increase survival over that with continuous PT among extremely premature infants (< 750 g BW or <27 weeks GA).
- Trial name
- NCT03927833
- Testing
- Phototherapy lights
- Where
- 19 sites in United States
- Volunteers
- 1,700 people
- Sponsor
- NICHD Neonatal Research Network
Bladder Cancer, Cervical Cancer
Health Education Counseling With or Without Bupropion in Helping African Americans Stop Smoking
RATIONALE: A stop-smoking plan that includes health education counseling and bupropion may help African-American smokers stop smoking.
- Conditions
- Bladder Cancer, Cervical Cancer, Esophageal Cancer, Gastric Cancer
- Trial name
- NCT00666978
- Testing
- smoking cessation intervention, bupropion hydrochloride, gene expression analysis
- Where
- 2 sites in United States
- Volunteers
- 540 people
- Sponsor
- Lisa Sanderson Cox, PhD
Systemic Light Chain Amyloidosis, Ocular Complications
The Impact of Systemic Light Chain Amyloidosis on Eyes
Study Purpose and Principle: Amyloidosis is a group of diseases characterized by the deposition of amyloid proteins in tissues and organs throughout the body, with common affected organs including kidneys, heart, nervous system…
- Trial name
- Amyloidosis (NCT06803082)
- Where
- China
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Donor Site Complication, Burn
Blue Light for Donor Site Healing in Burn Patients
The goal of this clinical trial is to learn whether blue light (BL) photobiomodulation can improve the healing of donor site (DS) wounds in patients with burn injuries who are treated surgically.
- Conditions
- Donor Site Complication, Burn, Photobiomodulation Therapy, Blue Light
- Trial name
- CGU01_BL (NCT07453927)
- Testing
- Photobiomodulation with blue light
- Where
- Italy
- Volunteers
- 25 people
- Sponsor
- AUSL Romagna Rimini
Premature; Infant, Light-for-dates
Re-feeding Gastric Residuals in Preterm Infants
The purpose of this study is to determine whether re-feeding of gastric residuals reduces the time needed to establish full enteral feedings in premature infants.
- Trial name
- NCT01420263
- Testing
- Re-feeding residuals, Fresh Feeding Breastmilk or Formula only
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- University of Alabama at Birmingham
Delirium, Postoperative Cognitive Dysfunction
Biomarkers Associated With Postoperative Cognitive Dysfunction
Loss of cognitive function after major surgery is a significant risk in older people. It can occur acutely in the days after surgery as delirium or in months to years later as a persistent reduction in brain function termed…
- Conditions
- Delirium, Postoperative Cognitive Dysfunction, Cognitive Decline, Cognitive Impairment
- Trial name
- NCT05464355
- Testing
- Intraoperative electroencephalography recording, Neurofilament light chain measurement, Tau protein measurement
- Where
- United Kingdom
- Volunteers
- 45 people
- Sponsor
- University of Oxford
Diabetic Polyneuropathy
Serum Neurofilament Light Chain Levels and Neuropathy Severity in Diabetic Polyneuropathy
Diabetic polyneuropathy (DPN) is one of the most common chronic complications of diabetes mellitus and is characterized by peripheral nerve damage caused by long-term hyperglycemia.
- Trial name
- DPN-NFL (NCT07480330)
- Testing
- Blood Sample Collection and Clinical Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 88 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Bladder Cancer
Detection of Bladder Tumors After 30 Min Instillation of Hexvix
The objective of the study is to compare Hexvix® flexible cystoscopy and white light flexible cystoscopy in the detection of histological confirmed bladder tumor lesions defined as dysplasia; CIS; Ta; T1; and ≥ T2 after 30…
- Trial name
- NCT01551407
- Testing
- Hexvix
- Where
- Germany
- Volunteers
- 38 people
- Sponsor
- Photocure
Metastatic Cancer, Melanoma
Evaluation of Pathway Modulation by Raf, MEK, & Kinase Inhibitors
This is a pilot study designed to evaluate the cutaneous effect of systemic inhibition of the tyrosine kinase pathway in the presence or absence of solar simulated light exposure.
- Conditions
- Metastatic Cancer, Melanoma, Colon Cancer, Differentiated Thyroid Cancer
- Trial name
- NCT03176485
- Testing
- Solar Simulator
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- University of Arizona
Surgery
Green Light for Post-Operative Wellness
This is an unblinded, parallel group randomized controlled trial to evaluate bright green light as an adjunct therapy after surgery at UPMC Shadyside.
- Trial name
- GLOW (NCT07218289)
- Testing
- Bright Green Light Therapy, Dim White Light Therapy
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Rebecca E Kotcher, MD
Retinopathy of Prematurity, Pain
The Effect of Eyemasks on Neonatal Stress Following Dilated Retinal Examination
Although screening exams for retinopathy of prematurity (ROP) prevent blindness they are physiologically stressful for infants. The investigators postulate that photosensitivity during mydriasis contributes to post-examination…
- Conditions
- Retinopathy of Prematurity, Pain, Premature Infant, Retinal Disease
- Trial name
- MASK-ROP (NCT03824782)
- Testing
- Phototherapy Mask
- Where
- Canada
- Volunteers
- 51 people
- Sponsor
- Sunnybrook Health Sciences Centre
Complication of Hemodialysis
REmoval of Free Light Chains. A COmpaRison of Three Different dialyzERs
Immunoglobulin light chains are classified as middle molecule uremic toxins able to interact with B lymphocyte membranes leading to the activation of transmembrane signaling.
- Trial name
- RECORDER (NCT02950389)
- Testing
- PMMA filter, HFR17 filter, F7 filter
- Where
- Italy
- Volunteers
- 20 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Postoperative Delirium (POD), Perioperative Neurocognitive Disorders
Ortopod CZ Pilot Study
ORTOPOD PILOT STUDY is a non-randomized, non-interventional clinical study that addresses the issue of perioperative neurocognitive disorder (deterioration of cognitive functions in the preoperative and perioperative period) and…
- Trial name
- ORTOPODCZ (NCT06869876)
- Where
- Czechia
- Volunteers
- 75 people
- Sponsor
- Tomas Bata Hospital, Czech Republic
Acute Kidney Injury, Inflammation
Light Therapy in Cardiopulmonary Bypass Surgery
The goal of this study is to determine whether or not exposure to blue spectrum light reduces acute kidney injury and systemic inflammation in subjects undergoing cardiopulmonary bypass.
- Trial name
- NCT02928887
- Testing
- Blue light
- Where
- United States
- Sponsor
- University of Pittsburgh
Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis
National Registry of Rare Kidney Diseases
The goal of this National Registry is to is to collect information from patients with rare kidney diseases, so that it that can be used for research.
- Conditions
- Adenine Phosphoribosyltransferase Deficiency, AH Amyloidosis, AHL Amyloidosis, AL Amyloidosis
- Trial name
- RaDaR (NCT06065852)
- Where
- United Kingdom
- Volunteers
- 35,000 people
- Sponsor
- UK Kidney Association