Clinical trials: Phototherapy Complication
Pain, Postoperative, Edema
Effectiveness of Light-emitting Diode (LED) Photobiomodulation in the Extraction of Retained Lower Third Molars
In dentistry, one of the most common surgical procedures is the removal of included third molars. This surgery generates great morbidity to patients for causing pain, edema and trismus due to surgical trauma.
- Conditions
- Pain, Postoperative, Edema, Trismus, Quality of Life
- Trial name
- NCT03442166
- Testing
- LED group
- Where
- Brazil
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Endometriosis
A Comparison of Narrow Band Imaging (NBI) and Standard White Light Laparoscopy to Detect Endometriosis
Endometriosis is a relatively common chronic gynecological condition that affects approximately 10% of all women of reproductive age.
- Trial name
- NCT01464775
- Testing
- Narrow Band Imaging (NBI), Standard White Light Laparoscopy
- Where
- 2 sites in United States
- Volunteers
- 167 people
- Sponsor
- Mercy Medical Center
Chronic Kidney Disease, Acute Myeloid Leukemia (AML)
Bone Marrow and Kidney Transplant for Patients With Chronic Kidney Disease and Blood Disorders
The main purpose of this study is to examine the outcome of a combined bone marrow and kidney transplant from a partially matched related (haploidentical or "haplo") donor.
- Conditions
- Chronic Kidney Disease, Acute Myeloid Leukemia (AML), Acute Lymphoblastic Leukemia (ALL), Chronic Myelogenous Leukemia (CML)
- Trial name
- BMT (NCT01758042)
- Testing
- Haploidentical Bone Marrow/Kidney
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Massachusetts General Hospital
Diabetes Mellitus, Amputation Stumps
Phototherapy in DM Amputation Ulcers.
Diabetes mellitus is a major public health problem and it is estimated that 300 million individuals will be affected by the year 2030.
- Conditions
- Diabetes Mellitus, Amputation Stumps, Diabetic Foot
- Trial name
- NCT02883751
- Testing
- LED, Control group
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Preterm Infant, Jaundice, Neonatal
BiLirubin Decrease Under Phototherapy Exposure in the Preterm Newborn in Incubator
Phototherapy is routinely used in neonatal intensive care units for the treatment of jaundice. Guidelines focus mainly on bilirubin serum levels to start the phototherapy.
- Conditions
- Preterm Infant, Jaundice, Neonatal, Phototherapy
- Trial name
- BLUE (NCT03942757)
- Testing
- bilirubin serum level determination, Phototherapy
- Where
- France
- Volunteers
- 200 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Depression, Major Depressive Disorder
Integrated Chronotherapy for Perinatal Depression
Perinatal depression is a common and serious mood disorder that increases morbidity and mortality in new mothers and results in poor infant/child outcomes.
- Conditions
- Depression, Major Depressive Disorder, Postpartum Depression
- Trial name
- NCT02053649
- Testing
- Triple Chronotherapy, Usual Care
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rhode Island Hospital
Cesarean Section; Complications, Wound, Dehiscence
Effect of Bioptron Light Therapy on Wound Healing After Caesarean Section
The purpose of this study is to investigate the effect of Bioptron light therapy on wound healing after caesarean section.
- Trial name
- NCT07693478
- Testing
- Standard Postoperative Medical Care, Bioptron Light Therapy
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cervical Cancer
Cervical Cancer Screening Study in Brazil
Objectives: Primary Objective: To perform a pilot clinical study to test multi-modal optical imaging for detection of cervical neoplasia in Brazil.
- Trial name
- NCT02335372
- Testing
- Wide-Field White Light Imaging, Acetic Acid, Proflavine Solution
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Vaginosis, Bacterial
Use of Blue Light Emitting Diode in the Treatment of Women With Bacterial Vaginosis: a Clinical Trial
Bacterial Vaginosis (BV) is a infectious process of the female genitourinary tract, an important health issue due to the high incidence and high rate of recurrence of the infection.
- Trial name
- NCT03500107
- Testing
- Blue Light Emitting Diode (LED) 401 +/- 5nm
- Where
- Brazil
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Centro de Atenção ao Assoalho Pélvico
Emergence Delirium, Anesthesia Emergence Delirium
Effect of Monochromatic Light on Incidence of Emergence Delirium in Children
Emergence delirium/emergence agitation (ED/EA) is a behavioral phenomenon of unclear etiology consisting of short lived behavioral changes that can be both traumatic to families and pose a safety risk to patients and staff.
- Trial name
- NCT03285243
- Testing
- Monochromatic blue light
- Where
- United States
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Baylor College of Medicine
Diabetic Neuropathy
NIR- and Multifrequent Impedance Spectroscopy on the Skin in Type 1 Diabetes
The aim of the study is to examine the suitability to detect diabetic neuropathy using NIR and impedance.
- Trial name
- NIR (NCT01707979)
- Where
- Denmark
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Lise Tarnow
Neonatal Jaundice, Phototherapy Complication
Continuous Versus Intermittent Phototherapy in Treatment of Neonatal Jaundice
One of the most common diseases in the neonatal period is indirect hyperbilirubinemia (IHB). After phototherapy was discovered accidentally in 1958, it has been used as the most effective treatment method for IHD for more than 60…
- Trial name
- NCT06386731
- Testing
- Intermittent Phototherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 225 people
- Sponsor
- Goztepe Prof Dr Suleyman Yalcın City Hospital
Reperfusion Injury, Post Cardiac Arrest Brain Injury
Light Utilization COX-Inhibitory Device Therapy for Infant Cardiac Arrest (LUTICA Study). The LUCID Device is Used in the Treatment of Ischemic Brain Reperfusion Injury Caused by Cardiac Arrest in Pediatric Patients.
Approximately 15,200 children receive cardiopulmonary resuscitation (CPR) for in-hospital cardiac arrest (IHCA) each year in the United States. Of these, about 60% are less than one year of age.
- Trial name
- LUTICA (NCT07556939)
- Testing
- LUTICIA - Light Utilization COX-Inhibitory Device)
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Mitovation, Inc
Myeloma Multiple, Plasma Cell Leukemia
The Norwegian Immunotherapy in Multiple Myeloma Study
The goal of this observational study is to study the effectiveness and complications of novel immunotherapies used in the treatment of multiple myeloma in routine care in Norway.
- Conditions
- Myeloma Multiple, Plasma Cell Leukemia, AL Amyloidosis
- Trial name
- NIMMS (NCT06855121)
- Testing
- Teclistamab, Elranatamab, Ciltacabtagene Autoleucel
- Where
- 23 sites in Norway
- Volunteers
- 400 people
- Sponsor
- St. Olavs Hospital
Bladder Cancer
A Study of Blue Light Flexible Cystoscopy With Cysview in the Detection of Bladder Cancer in the Surveillance Setting
The purpose of this study is to investigate if blue light cystoscopy with Cysview improves detection of tumors in patients with bladder cancer during surveillance cystoscopy, using the KARL STORZ D-Light C PDD Flexible Videoscope…
- Trial name
- NCT02560584
- Testing
- Hexaminolevulinate hydrochloride, KARL STORZ D-Light C PDD Flexible Videoscope System
- Where
- 17 sites in United States
- Volunteers
- 304 people
- Sponsor
- Photocure
Acute Kidney Injury, Liver Injury
Blue Light Therapy for Liver Surgery
The investigators hypothesize that subjects undergoing liver resection and who are exposed preoperatively to high illuminance blue spectrum light will exhibit reduced organ injury, specifically liver dysfunction, than subjects…
- Conditions
- Acute Kidney Injury, Liver Injury, Inflammation
- Trial name
- NCT02915081
- Testing
- Blue light
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Diabetes Mellitus, Type 2, Diabetic Retinopathy
Choroidal and Retinal Changes After RLRL Therapy in Diabetes and Diabetic Retinopathy
The choroidal thickness was found to be thinner in diabetic eyes without retinopathy compared to healthy eyes, thus choroidal thickness might be an important parameter for the development of diabetic retinopathy in diabetic eyes…
- Trial name
- NCT05773209
- Testing
- RLRL device
- Volunteers
- 58 people
- Sponsor
- The Second People's Hospital of Foshan
Low-Level Light Therapy, Renal Insufficiency, Chronic
Effects of Low Level Laser Therapy on Functional Capacity and DNA Damage of Patients With Chronic Kidney Failure
This study aims to verify the effects of low level laser therapy (LLLT) on functional capacity, DNA damage, lower limbs muscle strength, quadriceps muscle architecture, muscle pain and perception of lower limb fatigue…
- Conditions
- Low-Level Light Therapy, Renal Insufficiency, Chronic, Renal Dialysis, Clinical Trial
- Trial name
- NCT03250715
- Testing
- Low Level Laser Therapy
- Where
- Brazil
- Volunteers
- 28 people
- Sponsor
- Federal University of Health Science of Porto Alegre
Childhood-onset Systemic Lupus Erythematosus, Lupus Nephritis (LN)
Childhood-onset Lupus Nephritis Initial Glucocorticoid-dose Harmonization Trial (LIGHT Trial)
Childhood-onset systemic lupus erythematosus (cSLE) is a severe chronic autoimmune disease with a high burden of major-organ involvement.
- Trial name
- LIGHT (NCT07719140)
- Testing
- High-dose prednisone, Low-dose prednisone
- Where
- 8 sites in China
- Volunteers
- 198 people
- Sponsor
- Peking Union Medical College Hospital