Clinical trials: Phthalate Exposure
Phthalate Exposure, Bisphenol Exposure
Phthalate and Bisphenol Exposure During Minipuberty
Phthalates and bisphenols have been detected in a range of infant care products. This pilot study will test whether intervening on these sources of exposure during the critical period of minipuberty affects infants' body burden…
- Trial name
- NCT05864209
- Testing
- Phthalate- and Bisphenol-free Baby Products, Cloth Diapers, Conventional Disposable Diapers
- Where
- 2 sites in United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Renal Function Disorder, Glucose Metabolism Disorders
Phthalates Exposure in Type 2 Diabetic Patients and Diuretic Therapy
In this open clinical trial, 30 subjects with inadequately controlled T2D and eligible, as per good clinical practice, for therapy with SGLT-2 inhibitor, will be randomized to receive a SGLT-2 inhibitor vs other oral-antidiabetic…
- Trial name
- PURITY (NCT04242758)
- Testing
- Dapagliflozin 10 MG, Hydrochlorothiazide 12.5mg
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- University of Pisa
Infertility
Environment and Reproductive Health; Human Exposure to Bisphenol A, Phthalates and Fertility and Pregnancy Outcomes
The purpose of the study is to investigate the relationship between environmental agents and reproductive health. Environmental agents of interest include exposure to chemicals such as polychlorinated biphenyls (PCBs), flame…
- Trial name
- EARTH (NCT00011713)
- Testing
- Completion questionnaires/providing biological samples
- Where
- United States
- Volunteers
- 1,474 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Triple Negative Breast Cancer
Bisphenol and Phthalate Exposures in Triple Negative Breast Cancer
In this observational pilot study urine samples will be collected from women receiving neoadjuvant chemotherapy with doxorubicin for triple negative breast cancer to determine whether: 1) exposures bisphenol and phthalate levels…
- Trial name
- EDC-TNBC (NCT04268693)
- Testing
- urine collection
- Where
- United States
- Sponsor
- George Washington University
Diabetes Mellitus, Type 2, Albuminuria
Association Between Phthalates Exposure and Renal Function Impairment in TYpe 2 Diabetes
The global incidence of diabetic nephropathy (DN) is increasing, with no appreciable reduction in the percent of patients progressing toward end stage renal disease (ESRD) and dialysis (Tuttle et al, 2014, Winocour et al, 2018).
- Conditions
- Diabetes Mellitus, Type 2, Albuminuria, Cardiovascular Risk Factor
- Trial name
- PURITY-2 (NCT03622957)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- University of Pisa
Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure
Weight Loss and Endocrine Disrupting Chemicals (EDCs): Lifestyle Interventions to Lose Weight and Reduce EDC Exposure in Individuals With Overweight/Obesity
The goal of this study is to examine the relationship in individuals with overweight/obesity and endocrine disrupting chemical (EDC) exposure through a two-armed, randomized clinical trial.
- Conditions
- Obesity &Amp;Amp;Amp; Overweight, Environmental Exposure, Overweight (BMI > 25)
- Trial name
- LiveWell (NCT07560579)
- Testing
- Educational curriculum, Weight loss Application, Urinary EDC metabolite testing
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- Million Marker Wellness, Inc.