Clinical trials: Physical Activity, open to volunteers
Low Back Pain
Effect of Kinesiotaping Versus Endurance Exercise on Postmenopausal Low Back Pain
This study will be conducted to determine the effect of kinesiotaping versus endurance exercise on postmenopausal low back pain.
- Trial name
- NCT06771310
- Testing
- Endurance exercise, Kinesiotaping
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Emotion Management Skills, Lifestyle, Healthy
The Impact of Enhanced Music & Natural Visuals on Emotional Health
The investigators are conducting research on factors related to the self-regulation of mood and arousal states across a range of everyday activities as well as different levels of stress.
- Conditions
- Emotion Management Skills, Lifestyle, Healthy, Lifestyle Intervention, Recovery
- Trial name
- NCT07676110
- Testing
- soundBrilliance software application - Emotional Health
- Where
- 3 sites in United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- soundBrilliance LLC
Stress Urinary Incontinence (SUI)
Managing Impact-related Leakage During Exercise Using Intravaginal Support
The goal of this study is to evaluate the effectiveness of using a regular menstrual tampon or a Uresta pessary to reduce urine leakage associated with running-induced stress urinary incontinence (RI-SUI) in females aged 18 and…
- Trial name
- MILES (NCT07103161)
- Testing
- Uresta bladder support device, Sportex regular tampon
- Where
- Canada
- Volunteers
- 30 people
- Sponsor
- University of Ottawa
Upper Extremity Injuries, Questionnaire and Survey
Cross-Cultural Adaptation, Validity and Reliability of the Turkish Version of the Adolfsson-Björnsson Upper Extremity Activity Scale (ABAS)
Activity limitation is a common problem in individuals with upper extremity disorders. Many conditions involving the shoulder complex such as traumatic and non-traumatic upper extremity pain, subacromial impingement…
- Conditions
- Upper Extremity Injuries, Questionnaire and Survey, Reliability and Validity
- Trial name
- NCT06715397
- Testing
- No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Mustafa Kemal University
Cognitive Dysfunction, Mobility Limitation
Up-2 Study: Cognitively Engaging Walking Exercise and Neuromodulation to Enhance Brain Function in Older Adults
Declines in cognitive function and walking function are highly intertwined in older adults. A therapeutic approach that combines complex (cognitively engaging) aerobic walking exercise with non-invasive electrical brain…
- Conditions
- Cognitive Dysfunction, Mobility Limitation, Frail Elderly
- Trial name
- NCT05830942
- Testing
- Walking Exercise, Prefrontal Active tDCS
- Where
- 2 sites in United States
- Volunteers
- 120 people
- Sponsor
- University of Florida
Spinal Cord Injuries, Spinal Cord Injury Cervical
Activity-Based Therapy and Transcutaneous Spinal Cord Stimulation After Spinal Cord Injury (ABT-TCSCS)
The ABT-TCSCS study investigates how feasible and beneficial are activity-based therapy and transcutaneous spinal cord stimulation on improving of arm and hand recovery after cervical spinal cord injury.
- Trial name
- ABT-TCSCS (NCT06472986)
- Testing
- Activity-based therapy and transcutaneous spinal cord stimulation
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- University Health Network, Toronto
Chronic Neck Pain
Comparison of Cervical Retraction Exercise and Facet Oscillatory Mobilization in Chronic Mechanical Neck Pain
To compare the effects of Cervical Retraction Exercise and Facet Oscillatory Mobilization in chronic Mechanical Neck pain. To compare the effects of Cervical Retraction Exercise and Facet Oscillatory Mobilization in chronic…
- Trial name
- NCT06707870
- Testing
- Cervical retraction exercise, Facet oscillatory mobilization
- Where
- Pakistan
- Volunteers
- 32 people
- Sponsor
- Riphah International University
Type 1 Diabetes, Hypoglycemia
Impact of MEnstruation on Glycemic Response and Exercise In Females With Type 1 Diabetes
The objectives of this study are to examine how sex hormones (use of hormonal birth control, menstrual cycle phase) impact glycemic control among women with type 1 diabetes (T1D), and to test adjustments to insulin dosing and…
- Conditions
- Type 1 Diabetes, Hypoglycemia, Hyperglycaemia Due to Type 1 Diabetes Mellitus, Menstruation Disturbances
- Trial name
- MERIT (NCT06297980)
- Testing
- Personalized modifications to treatment to address menstrual cycle effects on glycemia
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Advanced Squamous Tumors
A Study to Assess the Adverse Events, Change in Disease Activity, and How Oral ABBV-711 Tablets Move Through the Body as a Monotherapy and in Combination With Intravenously Infused Budigalimab (ABBV-181), in Adults With Advanced Squamous Tumors
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess safety, tolerability, pharmacokinetics and preliminary efficacy of ABBV-711 as a monotherapy…
- Trial name
- NCT07241039
- Testing
- ABBV-711, Budigalimab
- Where
- 13 sites in United States, Canada and 2 more
- Volunteers
- 220 people
- Sponsor
- AbbVie
PARKINSON DISEASE (Disorder)
Feasibility of a Community-Based Multimodal Exercise Programme in Parkinson's Disease
This study aims to evaluate the feasibility and preliminary effectiveness of a multimodal, group-based but individualised therapeutic exercise programme for people with Parkinson's disease delivered within a real-world…
- Trial name
- NCT07618728
- Testing
- Exercise Group
- Where
- Spain
- Volunteers
- 64 people
- Sponsor
- Universidad Rey Juan Carlos
Advanced Solid Tumors, Malignant Neoplasm
A Clinical Trial of MK-2750 in Participants With Advanced Solid Tumors (MK-2750-002)
MK-2750 is a trial medicine designed to treat certain solid tumors. MK-2750 is a type of treatment called an antibody drug conjugate (ADC). ADCs attach to a protein on cancer cells and deliver medicine to destroy those cells.
- Trial name
- NCT07876128
- Testing
- MK-2750, 5-HT3 serotonin receptor antagonist, NK-1 receptor antagonist
- Volunteers
- 300 people
- Sponsor
- Merck Sharp & Dohme LLC
Breast Cancer, Exercise and Recovery
Research on the Development and Validation of Personalized Exercise Prescription System for Breast Cancer Patients Based on Large Language Models
The goal of this observational study is to develop and evaluate a large language model (LLM)-based decision support system for exercise prescription in breast cancer patients, aiming to provide personalized decision-making…
- Trial name
- NCT07767565
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Sedentary Behavior / Physical Inactivity, Aging
Effects of Different Amounts of Plyometric Exercise Without Jumping in Physically Inactive Older Adults
The goal of this clinical trial is to investigate whether different amounts of plyometric exercise without jumping can improve lower-limb muscle strength, power, and muscle and tendon mechanical properties in sedentary and/or…
- Trial name
- NJPT-OLDER (NCT07891000)
- Testing
- High-Volume Non-Jumping Plyometric Training, Low-Volume Non-Jumping Plyometric Training
- Volunteers
- 54 people
- Sponsor
- University of Americas - Chili
Heart Failure
Effect of Personalized Follow-up in Adapted Physical Activities in Subjects With Chronic Heart Failure.
France has one million people with heart failure (HF). Exercise intolerance, characterised by dyspnoea, is the main clinical symptom in HF patients and a key determinant of reduced quality of life.
- Trial name
- BougeTonCoeur (NCT06222762)
- Testing
- Experimental arm
- Where
- 2 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Brest
Exercise, Cardiac Function
Acute Cardiac Effects of Ultra-Trail Running
This prospective observational study aims to investigate the acute cardiovascular effects of ultra-endurance running using comprehensive echocardiographic assessment combined with biological analyses.
- Conditions
- Exercise, Cardiac Function, Echocardiography
- Trial name
- ULTRA-ECHO (NCT07753694)
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Major Depressive Disorder
Exercise-priming of CBT for Depression: the CBT+ Trial
This study investigates the effects of intentionally sequencing aerobic exercise immediately prior to cognitive behavioral therapy (CBT) to determine its effects on mechanisms of CBT (i.e., working alliance, behavioral…
- Trial name
- NCT07221929
- Testing
- Rest, Aerobic Activity
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Wisconsin, Madison
Sleep, Healthy Vollunteer
Wearable Sleep EEG and Auditory Stimulation in Healthy Adults
The purpose of this single-site pilot study is to evaluate the feasibility, usability, and technical performance of a wearable sleep-monitoring system that records electroencephalography (EEG) and delivers brief, low-volume…
- Trial name
- NCT07808645
- Testing
- Wearable EEG-Based Sleep Monitoring and Closed-Loop Auditory Stimulation System
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Houston
Knee Osteoarthritis
The Effect of Theory-driven Physiotherapy on Physical Activity in Knee OA.
Knee osteoarthritis (OA) is a leading cause of pain, disability, and reduced physical functioning worldwide. Although physiotherapy and physical activity are recommended as first-line treatments, many individuals with knee OA do…
- Trial name
- EXPLOR (NCT07901881)
- Testing
- EXPLOR-3
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- Mark van Loo
Healthy
Neurofeedback Training of Anterior Insula Activity Based on Unidimensional vs. Multidimensional Interoceptive Regulation Strategies
The purpose of this study is to compare the neural and behavioral effects of real-time functional magnetic resonance imaging (fMRI) neurofeedback training using two different interoceptive strategies: a unidimensional heartbeat…
- Trial name
- NCT07416370
- Testing
- real-time fMRI neurofeedback training
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Advanced Solid Tumors, Non-Small Cell Lung Cancer
A Study to Assess Adverse Events, Change in Disease Activity and How Intravenous ABBV-253 Moves Through the Body in Adult Participants With Advanced Solid Tumors
Cancer is a condition where cells in a specific part of body grow and reproduce uncontrollably. The purpose of this study is to assess adverse events, change in disease activity and pharmacokinetics of ABBV-253.
- Conditions
- Advanced Solid Tumors, Non-Small Cell Lung Cancer, Colorectal Cancer, Pancreatic Ductal Adenocarcinoma
- Trial name
- NCT07807956
- Testing
- ABBV-253
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- AbbVie
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