Clinical trials: Physical Activity
Autonomous Nervous System, Fatigue
Exploring Physiological Responses of Virtual Reality Walking Exercise Versus Treadmill Walking in Healthy Individuals
This study aimed to systematically compare the physiological responses generated by walking exercises conducted in a VR environment versus those performed on a treadmill, with a specific focus on their impacts on the autonomic…
- Trial name
- NCT06679348
- Testing
- walking exercise on treadmill, Treadmill walking exercise using VR
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Atlas University
Metastatic Cancer, Solid Tumor
Sym023 (Anti-TIM-3) in Patients With Advanced Solid Tumor Malignancies or Lymphomas
This was the first study to test Sym023 in humans. The primary purpose of this study was to see if Sym023 is safe and tolerable for patients with locally advanced/unresectable or metastatic solid tumor malignancies or lymphomas…
- Conditions
- Metastatic Cancer, Solid Tumor, Lymphoma
- Trial name
- NCT03489343
- Testing
- Sym023
- Where
- 4 sites in United States, Canada
- Volunteers
- 24 people
- Sponsor
- Symphogen A/S
Healthy
Effects of Modafinil, Caffeine and Methylphenidate in Healthy Volunteers
In this study the investigators compare three stimulants to each other. The effects of these agents on cognitive performance (eg, attention and memory) and on the brain are being measured.
- Trial name
- MKM (NCT02071615)
- Testing
- Methylphenidate 20 mg tablet given once by mouth, modafinil 200mg tablet given once by mouth, caffein 200mg tablet given once by mouth
- Where
- Germany
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Parkinson Disease
Effects of an Independent Walking Program With Walking Poles in People With Parkinson Disease
Study Purpose: The purpose of the study is to compare changes in activity levels and walking in people with Parkinson disease after an 8-week independent walking program with or without using walking poles.
- Trial name
- ActivatePD (NCT06908135)
- Testing
- Independent walking program using walking poles, Independent walking program without walking poles
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Pacific Northwest University of Health Sciences
Surgery, Immune System and Related Disorders
Immune Modulation by Enhanced vs Standard Prehabilitation Program Before Major Surgery
Over 30 million surgeries are performed annually in the US. Up to 30% of surgical patients experience delayed surgical recovery, marked by prolonged post-surgical pain, opioid consumption, and functional impairment, which…
- Conditions
- Surgery, Immune System and Related Disorders, Preoperative Care, Gastrointestinal Disease
- Trial name
- NCT04498208
- Testing
- Physical Prehabilitation, Stress Reduction Prehabilitation, Cognitive Prehabilitation
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Stanford University
Depression
A Feasibility and Preliminary Efficacy Study of an App-Based Physical Activity Intervention (MoodMover) for Depression
Exercise is recommended as a standalone treatment for mild-to-moderate depression in Canada. However, it's unclear how mental health practitioners can guide patients to structured, in-person exercise programs.
- Trial name
- NCT06573125
- Testing
- MoodMover
- Volunteers
- 36 people
- Sponsor
- University of British Columbia
Rural Health
Remote Exercise Program for Rural Men
The purpose of this study is to examine the feasibility, acceptability, and preliminary efficacy of a remote physical activity intervention designed for rural inactive men.
- Trial name
- NCT07224217
- Testing
- Remote Physical Activity Program (12 weeks), Delayed Remote Physical Activity Program (6 weeks)
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Resistance Training
Effects of Isometric Conditioning Activity on Subsequent Jumping Performance in Volleyball Players
The pairing of high-effort exercise, called conditioning activity, with a biomechanically similar high-velocity power movement is considered a valid method to effectively facilitate muscle power adaptations.
- Trial name
- NCT06459050
- Testing
- Dominant Limb Overcoming Isometric Conditioning Activity, Non-dominant Limb Overcoming Isometric Conditioning Activity
- Where
- Poland
- Volunteers
- 20 people
- Sponsor
- The Jerzy Kukuczka Academy of Physical Education in Katowice
Metabolism Disorder, Glucose, Physical Activity
Aerobic Treadmill Exercise And Metabolism
Overview- In this study, overweight or obese, sedentary participants (age=35-55 years, n=20) will be randomized to a 12-week control period or an aerobic exercise intervention.
- Conditions
- Metabolism Disorder, Glucose, Physical Activity, Sedentary Lifestyle
- Trial name
- The A-TEAM (NCT03162991)
- Testing
- Aerobic Exercise Intervention
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of South Carolina
Multiple Myeloma, Hematologic Neoplasms
The Feasibility of a Physical Activity Intervention for Advanced Multiple Myeloma Patients
Although physical activity (PA) is commonly used to manage symptoms and enhance quality of life (QOL) in cancer survivors, relatively little is known regarding the benefits in advanced multiple myeloma (MM).
- Conditions
- Multiple Myeloma, Hematologic Neoplasms, Advanced Cancer
- Trial name
- NCT04303091
- Testing
- Physical Activity for Advanced Cancer Treatment (PAACT)
- Where
- Canada
- Volunteers
- 19 people
- Sponsor
- Dr. Nicole Culos-Reed
Musculoskeletal Pain Disorder, Spinal Pain
Single Session Compared to Multiple Sessions of Education and Exercise for Older Adults With Spinal Pain in an Advanced Practice Physiotherapy Model of Care
Objectives: To assess the effectiveness and cost-effectiveness of a single session compared to multiple sessions of education and exercise for older adults with spinal pain treated conservatively in an advanced practice…
- Trial name
- NCT04868591
- Testing
- Single session of education and exercise provided by an advanced practice physiotherapist., Multiple session of education and exercise provided by an advanced practice physiotherapist.
- Where
- Canada
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Ciusss de L'Est de l'Île de Montréal
Old Age; Atrophy, Inflammatory Response
Effects of Parmigiano Reggiano on Skeletal Muscle Damage in Older Adults
Aging is associated with the loss of muscle mass and function (sarcopenia) and reduced tissue regenerative capacity. Eccentric exercise (ECC) is a model of RET that can be used with the elderly, due to the ability of the muscle…
- Conditions
- Old Age; Atrophy, Inflammatory Response, Muscle Soreness
- Trial name
- NCT04872374
- Testing
- Parmigiano Reggiano, Whey Protein
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Padova
Wearable Device, Cardiovascular Disease
HEARTS in Sync + CardioWatch 287-2
The goal of this interventional study is to evaluate the implementation, usability, and clinical outcomes of a wearable medical-grade device in a virtual Cardiac Rehabilitation (CR) program, titled HEARTS in Sync.
- Conditions
- Wearable Device, Cardiovascular Disease, ASCVD Management, CHF - Congestive Heart Failure
- Trial name
- NCT07322510
- Testing
- Remote Patient Monitoring with Corsano CardioWatch 287-2
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Nova Scotia Health Authority
Multiple Sclerosis, Gait Disorders, Neurologic
Walking and Thinking - Brain Activity During Complex Walking in People With Multiple Sclerosis
Every-day life means being part of a complex environment and performing complex tasks that usually involve a combination of motor and cognitive skills.
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Neuro-Degenerative Disease, Aging
- Trial name
- NCT05787704
- Testing
- No intervention
- Where
- Sweden
- Volunteers
- 41 people
- Sponsor
- Karolinska Institutet
Urinary Bladder, Overactive, Sexual Behavior
Comparative Study Between Behavior Therapy and Behavior Therapy Plus Mirabegron in Sexually Active Men With OAB Symptoms
The objective of this study is to evaluate and compare the therapeutic effects on OAB symptoms, and sexual functions, in terms of erectile function and ejaculatory function, in sexually active OAB male treated with behavior…
- Conditions
- Urinary Bladder, Overactive, Sexual Behavior, Sexual Activity, Behavior Therapy
- Trial name
- NCT04420533
- Testing
- Behavior therapy alone, Mirabegron 50 MG Extended Release Oral Tablet
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Statin Adverse Reaction
Exercise Intensity and Muscle Recovery in Statin Users
This study aims to investigate how different types and intensities of exercise affect muscle recovery in individuals taking statin medications compared to healthy controls.
- Trial name
- STN-EX (NCT07563452)
- Testing
- Dose-Escalation Exercise Protocol
- Where
- Austria
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Raffaele Mazzolari
Oropharynx Cancer
Staying Connected: a Mobile Health Study With the Noona® and Mobili-T® Systems
Mobile health applications are an attractive technological solution that facilitates access to care for patients conveniently and efficiently.
- Trial name
- NCT05368025
- Testing
- Mobili-T/Noona
- Where
- Canada
- Volunteers
- 65 people
- Sponsor
- University of Alberta
Covid19, Participation, Patient
The Effect of Covid-19 Process
Objective: The purpose of this study was to investigate the effect of the Covid-19 process on time management, participation, and leisure time activity. Methods: 531 individuals aged between 18-65 were included in the study.
- Trial name
- NCT04872725
- Testing
- Time management & participation & the leisure time activity
- Where
- Turkey (Türkiye)
- Volunteers
- 531 people, healthy volunteers welcome
- Sponsor
- Istanbul Medipol University Hospital
Type2 Diabetes Mellitus, Hyperglycemia
Heart Rate During Exercise in Type 2 Diabetes
Exercise training is a cornerstone for the prevention and treatment of metabolic disorders and associated cardiometabolic complications such as type 2 diabetes mellitus (T2D) and hypertension.
- Conditions
- Type2 Diabetes Mellitus, Hyperglycemia, Heart Rate, Exercise Training
- Trial name
- HRinT2DM (NCT03917576)
- Testing
- Behavioral, Exercise training intervention
- Where
- Chile
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Universidad de Los Lagos
Sciatica
Effects of Pilates Exercises and Neural Dynamic Mobilization in Sciatica Patients
The main purpose of the study is to find the effects of Pilates exercises and neural mobilization techniques on pain, flexibility and quality of life in sciatica patients.
- Trial name
- NCT05959317
- Testing
- Pilates Exercises, Neural dynamic mobilization
- Where
- 2 sites in Pakistan
- Volunteers
- 20 people
- Sponsor
- Riphah International University
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