Clinical trials: Physical Activity
Epilepsies, Partial
Effects of Diazepam on RNS Detections
To assess the magnitude and duration of reduction in RNS recorded Detections and Long Episodes following intranasal administration of Valtoco®.
- Trial name
- NCT05273398
- Testing
- nasal diazepam
- Where
- United States
- Volunteers
- 4 people
- Sponsor
- University of Cincinnati
Temporomandibular Disorder
INVESTIGATION AND COMPARISON OF THE EFFECTS OF POSTURE EXERCISES ON DYSFUNCTION, POSTURE AND BALANCE IN INDIVIDUALS WITH POSTERIOR EDENTULOUS AND FULL-TOOTHED TEMPOROMANDIBULAR DISORDER
The aim of this study is to investigate the relationship between neck posture and balance in patients with posterior edentulous and full-toothed temporomandibular disorder and to compare the effectiveness of the physiotherapy…
- Trial name
- NCT05704998
- Testing
- Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Dokuz Eylul University
Knee Osteoarthritis
Sensorimotor Training Versus Resistance Training in Patients With Knee Osteoarthritis
People with knee osteoarthritis (OA) have functional instability and defective neuromuscular function, it was recently suggested that sensorimotor exercises may be important and needed to improve the effectiveness of training…
- Trial name
- NCT01529398
- Testing
- Sensorimotor training (SMT), Resistance training (RT), Control group (CG)
- Where
- Brazil
- Volunteers
- 96 people
- Sponsor
- Federal University of São Paulo
Locally Advanced Lung Cancer; Metastatic Lung Cancer
Anti-PD-1 in Combination With Chemotherapy as First-Line Treatment to Lung Cancer
This is a Phase II, open-label, 4-cohort study of the monoclonal antibody BGB-A317 in combination with standard platinum-based chemotherapy in participants with advanced NSCLC or SCLC.
- Trial name
- NCT03432598
- Testing
- Tislelizumab, Paclitaxel, Gemcitabine
- Where
- 7 sites in China
- Volunteers
- 54 people
- Sponsor
- BeiGene
Heart Failure
Evaluation of the Entresto Effect on Sympathic Nervous System in Patient With Heart Failure
The hyperactivation of the sympathetic nervous system is a feature of the heart failure and the determinants of disease progression and risk of sudden cardiac death.
- Trial name
- B2AN-SNS (NCT02787798)
- Testing
- valsartan/sacubitril 100 mg, valsartan/sacubitril 200 mg, Microneurography
- Where
- France
- Volunteers
- 4 people
- Sponsor
- University Hospital, Toulouse
Solid Tumors, Pancreatic Cancer
CTS2190 Phase I /II Clinical Study in Patients
This is a first in human study in patients with advanced or metastatic solid tumors. The first part of the study is an open-label, dose escalation and the second part is an open label dose expansion in specific tumor types.
- Conditions
- Solid Tumors, Pancreatic Cancer, Non-small Cell Lung Cancer, Triple-negative Breast Cancer
- Trial name
- NCT06224387
- Testing
- CTS2190 capsules
- Where
- 2 sites in China
- Volunteers
- 224 people
- Sponsor
- CytosinLab Therapeutics Co., Ltd.
Nicotine Dependence, Drug Abuse
Effects of Nicotine on Cognitive Task Performance and Brain Activity as Measured by fMRI
Background: Many cigarette smokers claim that smoking improves their ability to think and concentrate, and have reported problems in thinking and concentration after quitting smoking.
- Trial name
- NCT01036711
- Where
- United States
- Volunteers
- 249 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Good Health
Measurement of a Systolic Pressure Index at the Toe After a Walking Test
The main objective of this study is to evaluate the concordance of the variation in systolic pressure indices measured at the toe and ankle after a walking test in healthy volunteers.
- Trial name
- IPSO FACTO (NCT01750944)
- Testing
- Ankle first, Toe first
- Where
- France
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Stroke, Upper-limb Paresis
Automatic Versus Intentional Movement Exercises to Enhance Arm Functions After Stroke
Many patients retain upper-limb motor impairment following stroke. Most conventional rehabilitation techniques are aimed to improve motor intentional movement by repeated exercises.
- Trial name
- AUTOTAB (NCT01565044)
- Testing
- motor training
- Where
- France
- Volunteers
- 26 people
- Sponsor
- Hospices Civils de Lyon
Schizophrenia
Roflumilast Plus Antipsychotics Proof of Mechanism Study in Schizophrenia
The purpose of this study is to determine whether cognitive impairment associated with schizophrenia is attenuated by add-on roflumilast administration to second generation antipsychotics (SGA) in participants with stable…
- Trial name
- NCT02079844
- Testing
- Roflumilast, Second generation antipsychotic
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Takeda
Metastatic Prostate Cancer
Enzalutamide Plus Talazoparib for the Treatment of Hormone Sensitive Prostate Cancer (ZZ-First)
This is a multicenter, open-label, randomized, two-arm, phase II clinical trial to evaluate the efficacy and safety of talazoparib (PF-06944076) in combination with enzalutamide in patients with metastatic hormone-naïve prostate…
- Trial name
- ZZ-First (NCT04332744)
- Testing
- Enzalutamide, Talazoparib
- Where
- 8 sites in Spain
- Volunteers
- 54 people
- Sponsor
- MedSIR
ARDS (Moderate or Severe)
FAPI PET/CT to Detect Fibroblast Activity in Non-resolving ARDS
Of patients requiring mechanical ventilation in the ICU 23% meet criteria of the Acute Respiratory Distress Syndrome (ARDS). Mortality of this syndrome remains high (35-46%) in moderate and severe ARDS.
- Trial name
- FAPI ARDS (NCT06691464)
- Testing
- PET
- Where
- Netherlands
- Volunteers
- 20 people
- Sponsor
- University Medical Center Groningen
Cancer, Advanced Solid Tumor
StrataPATH™ (Precision Indications for Approved Therapies)
StrataPATH™ is a non-randomized, open-label trial designed to explore efficacy and safety of multiple FDA-approved and commercially available cancer therapies in new, biomarker-guided patient populations.
- Trial name
- StrataPATH (NCT05097599)
- Testing
- lorlatinib, encorafenib + binimetinib, talazoparib
- Where
- 4 sites in United States
- Volunteers
- 11 people
- Sponsor
- Strata Oncology
Cirrhosis
BCAA Supplemental Study
The central hypothesis of this study is that BCAA supplementation and BCAA supplementation plus low-intensity activity will improve muscle mass and HRQOL in cirrhotic patients compared to usual care
- Trial name
- NCT03339232
- Testing
- BCAA Supplement, Physical Activity
- Where
- United States
- Volunteers
- 26 people
- Sponsor
- Loyola University
Prader-Willi Syndrome
Cortisol Activity in Patients With Prader-Willi Syndrome and Healthy Controls
The purpose of the study is to find out if people with Prader-Willi syndrome have a difference in the protein which changes inactive cortisone to the active stress hormone cortisol.
- Trial name
- NCT00932932
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
COPD, Pulmonary Rehabilitation
Tele-based Resisted Exercise for COPD
The present study aims to investigate the effect of six weeks tele-based resisted exercises on cardiopulmonary function, quality of life, muscle strength and functioanl performance among patients with chronic obstructive…
- Conditions
- COPD, Pulmonary Rehabilitation, Telerehabilitation, Cardiopulmonary Exercise Test
- Trial name
- NCT04870632
- Testing
- Education, Video-based pulmonary rehabilitation, Booklet-based pulmonary rehabilitation
- Where
- Taiwan
- Volunteers
- 40 people
- Sponsor
- National Cheng-Kung University Hospital
Premature Ejaculation
The Impact and Benefit of Physical Activity on Premature Ejaculation
The purpose of this study is to investigate the relationship between physical activity and PE, and determine whether moderate physical activity might delay ejaculation time or be an alternative treatment for PE.
- Trial name
- PE (NCT02844998)
- Testing
- physical activity, dapoxetine 30 mg on demand
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Ankara Training and Research Hospital
Premenstrual Syndrome
Physical Activity Level, Aerobic Capacity and Dietary Habits Among a Cohort of Females With Premenstrual Syndrome
The aim of the study is to investigate the physical activity level, aerobic capacity and dietary habits among a cohort of females with premenstrual syndrome
- Trial name
- NCT04901598
- Testing
- Running anaerobic sprint test and aerobic test
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis
Prehabilitation Physical Activity in Persons With Osteoarthritis
Knee joint osteoarthritis (OA) reduces functional mobility and performance of daily tasks such as rising from a chair. Therefore interventions aimed at improving muscle strength and sit-to-stand task performance are very…
- Trial name
- PrehabOA (NCT02881463)
- Testing
- therapeutical exercises
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Tartu
Digital Technology, Healthy
A Vision-Based Characterization of Human Movement Scaling in Large-Amplitude Tasks
This pilot study investigates the feasibility of objectively quantifying movement amplitude and amplitude decay during large-amplitude exercises using RGB camera-based video analysis in healthy volunteers.
- Trial name
- NCT07387887
- Testing
- Large-Amplitude Exercise Observation and Video Recording
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Biruni University
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