Clinical trials: Physical Activity
Metabolic Syndrome
Evaluating the Effectiveness of a Community Exercise Program to Reduce the Risk of Metabolic Syndrome Among Black Americans
Black Americans with a family history of early heart disease tend to have a group of risk factors that can contribute to heart disease.
- Trial name
- NCT00783445
- Testing
- Community-Based Exercise Program (C-FIT), Self-Help Exercise Program (HOME)
- Where
- United States
- Volunteers
- 204 people
- Sponsor
- Johns Hopkins University
Chronic Low Back Pain
Behavioral Exercise Therapy and Multidisciplinary Rehabilitation for Chronic Non-specific Low Back Pain
Multidisciplinary behavioral-orthopedic rehabilitation in the treatment of chronic back pain has proven its short-term effectiveness. Exercise therapy plays a major role in such a combination of treatments.
- Trial name
- VBT (NCT01666639)
- Testing
- Behavioral Medical Rehabilitation plus behavioral exercise therapy, Usual Behavioral Medical Rehabilitation
- Where
- 3 sites in Germany
- Volunteers
- 351 people
- Sponsor
- University of Erlangen-Nürnberg
Cervicogenic Headache, Headache
Effects of Manual Therapy on the Upper Cervical Spine Combined With Exercise vs Isolated Exercise in Patients With Cervicogenic Headache.
Cervicogenic headache is defined as unilateral headache associated with neck pain. Effect of manual translatoric therapy of the upper cervical spine associated with cervical exercises in these patients is currently unknown.
- Trial name
- NCT04401501
- Testing
- Manual Therapy and Exercises, Exercise
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Universidad de Zaragoza
Preterm Infants, Respiratory Distress Syndrome
Diaphragm Electrical Activity of Preterm Infants on nCPAP With Binasal Prongs Versus RAM Cannula
Preterm babies have immature lungs and frequent pauses in their breathing which often necessitates breathing support. Nasal Continuous Positive Airway Pressure (nCPAP) is one of the most commonly used tools, but the standard…
- Conditions
- Preterm Infants, Respiratory Distress Syndrome, CPAP, RAM Cannula
- Trial name
- NCT03121781
- Testing
- respiratory support- interface
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Sunnybrook Health Sciences Centre
Dementia, Mild Cognitive Impairment (MCI)
Combating Alzheimer's Through Sleep and Exercise
The Combating Alzheimer's through Sleep and Exercise (CASE) study is an exploratory, hypothesis-generating trial designed to: (1) assess whether improvements in sleep are associated with improvements in cognitive performance and…
- Conditions
- Dementia, Mild Cognitive Impairment (MCI), Cognitively Unimpaired, Alzheimer's Dementia (AD)
- Trial name
- CASE (NCT04855630)
- Testing
- Elemind Neuromodulation Headband, Exercise Routine
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Miami
Post-COVID-19 Syndrome, Long-COVID-19 Syndrome
Aerobic Training for Rehabilitation of Patients With Post Covid-19 Syndrome
Post-COVID-19 syndrome (PCS) occurs as a sequelae after acute infection with the SARS-CoV-2 virus (COVID-19 infection). PCS is defined as symptom persistence over a period of 12 weeks from infection and/or the appearance of new…
- Trial name
- NCT06016192
- Testing
- Aerobic Exercise Training
- Where
- Germany
- Volunteers
- 139 people
- Sponsor
- University of Witten/Herdecke
Diabetes Mellitus, Type 1, Endothelial Dysfunction
Therapeutic Strategies for Microvascular Dysfunction in Type 1 Diabetes
The investigators will test the hypothesis that, in adults with type 1 diabetes (T1D), glucagon-like peptide-1 receptor agonism (GLP-1RA, i.e.
- Trial name
- MCD-1 (NCT05478707)
- Testing
- Dulaglutide
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- AdventHealth Translational Research Institute
Breast Cancer, Quality of Life
Physical Activity Intervention for Young Cancer Survivors
The proposed mixed methods pilot study will enroll 20 young breast cancer survivors into a 12-week technology-based, remotely-delivered, peer-moderated physical activity program to examine the effects of the intervention on…
- Conditions
- Breast Cancer, Quality of Life, Physical Activity
- Trial name
- NCT04064892
- Testing
- Exercise Intervention
- Where
- United States
- Volunteers
- 34 people
- Sponsor
- University of California, San Diego
Metastatic Cancer, Carcinoma
Using a PET Imaging Agent, 18F-Clofarabine (CFA), to Measure Deoxycytidine Kinase Activity in Metastatic Cancer
The purpose of this study is to evaluate whether a new type of imaging study, called 18F-Clofarabine (CFA) PET/CT, can be used to image cancer pyrimidine metabolism in participants.
- Conditions
- Metastatic Cancer, Carcinoma, Adenocarcinoma
- Trial name
- NCT05065736
- Testing
- 18F-Clofarabine
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Roberto Vargas
Muscle Weakness | Patient, Quality of Life
Impact of Underwater Exercise Versus Regular Aerobic Exercise on Quality of Life and Power of Muscle
To investigate the Impact of underwater exercise versus regular aerobic exercise on quality of life and power of muscle
- Trial name
- NCT07132736
- Testing
- Hubbard tank, Mat on the ground
- Where
- Jordan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- October 6 University
Advanced Solid Malignancies
Study of AZD9150 and MEDI4736 (Durvalumab) in Japanese Adult Patients With Advanced Solid Malignancies
This is a phase I, open-label study to assess the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of AZD9150 monotherapy and AZD9150 in combination with durvalumab in Japanese patients with advanced…
- Trial name
- NCT03394144
- Testing
- AZD9150, Durvalumab
- Where
- 2 sites in Japan
- Volunteers
- 11 people
- Sponsor
- AstraZeneca
Chest Pain
N-terminal Pro B-type Natriuretic Peptide (Nt-proBNP) Versus Exercise Test for Evaluation of Acute Chest Pain
The investigators' objective is to compare a new strategy combining clinical history and NT-proBNP levels versus the usual care, consisting of early exercise testing, for decision making in patients presenting to the emergency…
- Trial name
- NCT00493844
- Testing
- Exercise testing, Clinical evaluation + NTproBNP
- Where
- Spain
- Volunteers
- 320 people
- Sponsor
- University of Valencia
Coronary Disease, Hypolipoproteinemia
Exercise Versus Niacin in Patients With Coronary Artery Disease (CAD) and Low High-Density Lipoproteins (HDL)
The investigators want to study the relative effects of physical exercise vs. extended-release niacin (lipid-lowering drug) in patients with coronary heart disease and low HDL cholesterol ("good cholesterol") on lipid profile…
- Trial name
- NCT00298909
- Testing
- physical exercise, niaspan (extended-release niacin), niacin
- Where
- Germany
- Volunteers
- 48 people
- Sponsor
- University of Leipzig
Hospitalism
Effect of Physiotherapy and Rehabilitation Program on Physical Activity Level in the Elderly Inpatient
In inpatient older adults, decrement in their mobility and loss in their physical activity are seen in time line between their hospitalization and discharge.
- Trial name
- NCT03516032
- Testing
- exercises
- Volunteers
- 323 people
- Sponsor
- Hacettepe University
Heart Failure and Preserved Ejection Fraction, Obesity & Overweight
eHealth Lifestyle Intervention To Enhance Outcomes in HFpEF
The goal of this clinical trial is to learn if a digital lifestyle education program improves exercise capacity in adults who have heart failure with preserved ejection fraction (HFpEF) and overweight or obesity.
- Conditions
- Heart Failure and Preserved Ejection Fraction, Obesity & Overweight, Heart Failure
- Trial name
- ELITE-HFpEF (NCT07661732)
- Testing
- Digital lifestyle education program, Usual Care
- Where
- Spain
- Volunteers
- 52 people
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Pregnancy
Effect During Pregnancy and Intrapartum Health
Assessing the role of moderate exercise in newborn intrapartum variables have showed to be crucial not only on prescribing exercise safely, but also on understanding its impact on the prevention of some cardio-metabolic diseases…
- Trial name
- NCT03348332
- Testing
- Exercise pregnant women
- Where
- Spain
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Physical Activity, Sedentary Lifestyle
Pilot Data Collection for Activity, Adiposity, and Appetite in Adolescents
The goal of this study is to quantify energy metabolism using indirect calorimetry at rest, in the presence of excess energy following a meal, and in response to the demand for energy during exercise.
- Conditions
- Physical Activity, Sedentary Lifestyle, Metabolism, Energy Balance
- Trial name
- AAAA (NCT03157063)
- Testing
- Data Collection Procedures
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Children's Mercy Hospital Kansas City
Temporomandibular Joint Disorders
Miofascial Release and Exercises Therapy in the Treatment of Temporomandibular Disorders
Objectives: The aim of this research is to compare the effectiveness of myofascial release therapy and exercise therapy on pain, quality of sleep, anxiety, trigger points, and joint sounds in individuals with temporomandibular…
- Trial name
- NCT02540863
- Testing
- myofascial release protocol and Rocabado exercise therapy, exercise therapy
- Volunteers
- 64 people
- Sponsor
- Universidad de Almeria
Multiple Sclerosis
Efficacy of Square- Stepping Exercises in Individuals With Multiple Sclerosis
Square stepping exercises can promote correct foot placement, fast and coordinated step patterns, and sensory-motor interaction.
- Trial name
- NCT05682963
- Testing
- Square Step Exercises Program, Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Pamukkale University
Osteoporosis or Osteopenia
What is the Best Policy to Prevent Osteoporotic Fracture?
This study aims to conduct a cost-effectiveness analysis (CEA) among the programs for preventing osteoporotic fracture. The main comparison will be made among the effects of three programs for preventing osteoporotic fractures…
- Trial name
- NCT00173693
- Testing
- exercise for strength, balance, health education
- Where
- Taiwan
- Sponsor
- National Taiwan University Hospital
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