Clinical trials: Physical Activity
Spinal Cord Injuries, Physical Inactivity
An Online Rehabilitation Programme for People with SCI
The goal of this feasibility study is to explore the feasibility and effectiveness of a 12-week online rehabilitation programme in people with Spinal Cord Injury during the transition from hospital to home.
- Conditions
- Spinal Cord Injuries, Physical Inactivity, Spinal Cord Injury, Acute
- Trial name
- NCT06583538
- Testing
- Giraffe Healthcare
- Where
- United Kingdom
- Volunteers
- 15 people
- Sponsor
- Glasgow Caledonian University
Body Composition, Exercise Test
Identification of Sports Talents in Boxers
This study aims to identify sporting talents by profiling a group of young boxers residing in the State of Mexico using unsupervised machine learning methods.
- Conditions
- Body Composition, Exercise Test, Psychological Well-Being
- Trial name
- NCT06269848
- Where
- Mexico
- Volunteers
- 178 people
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Solid Tumor Cancers
A First-in-human Study to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Preliminary Anti-tumour Activity of TAX2 in Patients With Relapsed/Refractory Advanced/Metastatic Solid Tumours
The purpose of this clinical trial is to investigate the treatment for adult patients suffering from advanced or metastatic solid tumours and has 2 parts to the study: the Phase 1 where ascending doses of the experimental study…
- Trial name
- APM-CT001 (NCT07688148)
- Testing
- TAX2
- Where
- 4 sites in Belgium, France
- Volunteers
- 48 people
- Sponsor
- Apmonia Therapeutics
Spasticity, Muscle
Effect of Transcutaneous Auricular Nerve Stimulation vs Body Rocking Exercises on Spasticity of Upper Limb
The primary aim of this study is to compare the effect of TANS and body rocking exercises on reducing upper limb spasticity in young stroke patients( under 50).
- Trial name
- NCT06914115
- Testing
- TANS Group, Body Rocking Exercise
- Where
- Pakistan
- Volunteers
- 42 people
- Sponsor
- Superior University
Primary Biliary Cholangitis
EXerCise Intervention in cholesTatic LivEr Disease: The EXCITED Study
A prospective, single centre, single-arm, pilot study investigating the safety and efficacy of a 12-week remotely-monitored home-based exercise program in patients with refractory fatigue (based on PBC-40 Quality of Life measure)…
- Trial name
- EXCITED (NCT04265235)
- Testing
- Home-based exercise program
- Where
- United Kingdom
- Volunteers
- 31 people
- Sponsor
- University of Birmingham
Relapsed Hodgkin Lymphoma, Refractory Hodgkin Lymphoma
Study of PD-1 Inhibitors After CD30.CAR T Cell Therapy in Relapsed/Refractory Hodgkin Lymphoma
LCCC1852-ATL is a prospective 2-arm study designed to determine if chimeric antigen receptor T (CAR-T) cells result in immunomodulation which can be subsequently exploited by programmed cell death protein 1 (PD-1) antibodies to…
- Trial name
- NCT04134325
- Testing
- Nivolumab, Pembrolizumab
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- UNC Lineberger Comprehensive Cancer Center
Exercise Fatigue
Development and Evaluation of Functional Probiotic Powder in Human Trials
Purpose: To optimize the preparation process of probiotic powder and assess its impact on healthy athletes, providing a scientific basis for functional foods.
- Trial name
- FPPHT (NCT06760468)
- Testing
- Control, Experimental Group
- Volunteers
- 60 people
- Sponsor
- Chengdu Sport University
Osteoarthritis, Knee
STepped Exercise Program for Knee OsteoArthritis
Knee osteoarthritis (OA) is one of the most common chronic conditions and a leading cause of disability among Veterans. Although exercise is known to improve pain, physical abilities, and other outcomes for patients who have knee…
- Trial name
- STEP-KOA (NCT02653768)
- Testing
- Stepped Exercise Program, Arthritis Education
- Where
- United States
- Volunteers
- 345 people
- Sponsor
- VA Office of Research and Development
Amputation, Telerehabilitation
Telerehabilitation in Individuals With Unilateral Transtibial Amputation
It is aimed to investigate the effects of telerehabilitation-based structured exercise on muscle strength, balance, performance, body image, prosthesis adaptation, activity limitation, prosthesis use satisfaction, and quality of…
- Conditions
- Amputation, Telerehabilitation, Exercise, Prosthesis User
- Trial name
- NCT04968691
- Testing
- Telerehabilitation based exercise treatment, Home based exercise treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Mehmet Kurtaran
Refractory Acute Myeloid Leukemia (AML), Relapsed Acute Myeloid Leukemia (AML)
CD64 CAR T Cell Therapy in Adults With Relapsed and/or Refractory AML
This is a Phase 1, open label, dose-escalation study to evaluate the safety, expansion, persistence, and preliminary clinical activity of lentivirally transduced autologous T cells expressing anti-CD64 chimeric antigen receptors…
- Conditions
- Refractory Acute Myeloid Leukemia (AML), Relapsed Acute Myeloid Leukemia (AML), Myelodysplastic Syndrome, AML (Acute Myeloid Leukemia)
- Trial name
- NCT07347418
- Testing
- CD64 CAR T Cells
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- University of Colorado, Denver
Chronic Lymphocytic Leukemia
FCM-R (Fludarabine, Cyclophosphamide, Mitoxantrone, Rituximab) in Previously Untreated Patients With Chronic Lymphocytic Leukemia (CLL) < 70 Years
The goal of this clinical research study is to learn if using a combination of fludarabine, cyclophosphamide, and mitoxantrone plus rituximab, with the growth factor pegylated filgrastim, will improve the response to treatment…
- Trial name
- NCT00254410
- Testing
- Fludarabine, Cyclophosphamide, Mitoxantrone
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- M.D. Anderson Cancer Center
Chronic Heart Failure, Aging
Comparing the Effects of Combining Cognitive and Physical Exercise Training on Cognition, and Cerebral Blood Flow Regulation in Men and Women With Chronic Heart Failure
The objective of this project is to assess the effects of combined physical exercise and cognitive training interventions on cognitive and brain health in patients with heart failure (HF).
- Trial name
- ReCARDIO (NCT04970888)
- Testing
- Cognitive training, Exercise training, Usual care
- Where
- Canada
- Volunteers
- 216 people
- Sponsor
- Montreal Heart Institute
Genital Neoplasms, Female, Lymphedema
Effect of Early Compression and Exercise on Lymphedema Incidence in Patients With Gynecological Cancer
Objectives: 1) To evaluate the effect of early compression therapy with individualized exercise on the incidence of lower limb lymphedema at 12 months post-operatively in patients treated for gynecological cancer who are at risk…
- Trial name
- NCT02966327
- Testing
- Bilateral leg compression stockings, Individualized exercise, Lymphedema risk reduction
- Where
- Canada
- Volunteers
- 50 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Breast Cancer Prevention
MELIORA Virtual Coach Intervention for Breast Cancer Prevention
Breast cancer (BC) is the most commonly diagnosed cancer in women worldwide, with early-onset cases increasing due to genetic and lifestyle factors.
- Trial name
- MELIORA (NCT07200427)
- Testing
- MELIORA Virtual Coach Intervention, Control (generic advice)
- Where
- 7 sites in Greece, Lithuania and 2 more
- Volunteers
- 2,080 people, healthy volunteers welcome
- Sponsor
- Harokopio University
Hypertension
Treatment of Hypertension With Two Exercise Intensities
To determine whether exercise training could significantly replace medication as a treatment for mild essential hypertension.
- Trial name
- NCT00004561
- Testing
- exercise
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Metabolic Syndrome, Prediabetes
Effects of Postprandial Walking and Resistance Snacking on Glucose Responses in Adults With Metabolic Syndrome
This study will examine whether light physical activity after meals can improve 24-hour glucose responses in adults with metabolic syndrome and prediabetes.
- Trial name
- BITE (NCT07620886)
- Testing
- Postprandial walking, Brief resistance exercise snacks
- Volunteers
- 25 people
- Sponsor
- Seoul National University
Polycystic Ovary Syndrome, Insulin Resistance
PCOS & Insulin Resistance Exercise Study
This study evaluates the feasibility and metabolic effects of implementing a structured exercise program in women with polycystic ovary syndrome and insulin resistance.
- Trial name
- NCT02303470
- Testing
- Vigorous Exercise, Moderate Exercise
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Carcinoma, Hepatocellular, Gastric/Gastroesophageal Junction Cancer
A Study to Investigate Sitravatinib as Monotherapy and in Combination With Tislelizumab in Participants With Unresectable Locally Advanced or Metastatic Hepatocellular Carcinoma or Gastric/Gastroesophageal Junction Cancer
The purpose of this study was to evaluate the safety, tolerability, pharmacokinetics and preliminary antitumor activity of sitravatinib as monotherapy and in combination with tislelizumab in participants with unresectable locally…
- Trial name
- NCT03941873
- Testing
- Sitravatinib, Tislelizumab
- Where
- 18 sites in China
- Volunteers
- 111 people
- Sponsor
- BeiGene
Depression
Cognitive Behavioural Couple Intervention Therapy for Chinese Couples With a Depressed Partner
Understanding depression from a relational perspective maybe more meaningful in Chinese culture due to the different values and beliefs among Chinese comparing to those of the Western cultures.
- Trial name
- NCT04590573
- Testing
- Cognitive behavioural couple therapy (CBCT), Emotion focused couple therapy (EFCT), Wait-list control (Control)
- Where
- Hong Kong
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in Elderly Patients With Chemotherapy
Buerger's Exercises and Proprioceptive Drills on Postural Stability and Foot Perfusion in Elderly Patients With Chemotherapy
Chemotherapy-induced peripheral neuropathy (CIPN) is a common, dose-limiting side effect of neurotoxic chemotherapy agents, characterized by sensory loss, impaired proprioception, and muscle weakness, predominantly affecting the…
- Trial name
- NCT07756073
- Testing
- Buerger's Exercises
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- South Valley University
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