Clinical trials: Physical Dependence
Mobility Limitation, Physical Activity
PREPA PREvention of Loss of Autonomy
According to several reports, the proportion of people aged 80yrs or older will be doubled within the next 25y, reaching 10% of the global population.
- Trial name
- PREPA (NCT03667664)
- Testing
- Multidimensional assessments, Multicomponent group-based and supervised exercise program, Follow-up at T3 + 6 months and T3 + 12 months
- Where
- France
- Volunteers
- 530 people
- Sponsor
- Hospices Civils de Lyon
Tobacco Dependence
Assessment of Biomarkers in Children to Help Parents Quit Tobacco
This randomized controlled trial will test whether adding biomarker measurement and informed outreach for tobacco smoke exposure as part of routine practice increases identification and improves treatment, effectiveness, and…
- Trial name
- ABC Quit (NCT04832659)
- Testing
- CEASE, CEASE + BIO
- Where
- United States
- Volunteers
- 865 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Opioid Dependence
An Assessment of Fentanyl Dose Requirements in Opioid-maintained Individuals
This study seeks to determine the suitable doses of fentanyl with acceptable adverse effect and safety profile in opioid-dependent patients.
- Trial name
- FEN001 (NCT01358500)
- Testing
- Fentanyl
- Where
- Australia
- Volunteers
- 24 people
- Sponsor
- University of Adelaide
Nervous System Diseases, Oculomotor; Disorder
Innovative Physical Therapy Modalities in People With a Neurological Disease: Oculomotor Therapy and Adapted Yoga
Physiotherapy is a discipline which englobe not only the rehabilitation of physical pathologies but also their prevention. That is why this study pretends to upgrade this part of the physical therapy specialty while prove new…
- Conditions
- Nervous System Diseases, Oculomotor; Disorder, Physical Dependence, Physical Inactivity
- Trial name
- NeuPhysioLRG (NCT05709691)
- Testing
- Oculomotor therapy, Adapted yoga
- Where
- Spain
- Volunteers
- 128 people
- Sponsor
- University of Malaga
Methamphetamine Dependence, Methamphetamine Abuse
Varenicline as a Treatment for Methamphetamine Dependence
The primary purpose of the study is to determine the effects of treatment with varenicline (1 and 2 mg daily), compared to treatment with placebo, on methamphetamine-induced craving and subjective effects in…
- Conditions
- Methamphetamine Dependence, Methamphetamine Abuse, Substance Abuse
- Trial name
- Varenicline (NCT01571167)
- Testing
- Varenicline
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Baylor College of Medicine
Nicotine Dependence
Assessment of Craving in Nicotine-Dependent Patients With Schizophrenia Using Virtual Reality
Background: The prevalence of cigarette smoking among individuals with schizophrenia is noticeably higher than in the general population, and smoking cessation attempts frequently are unsuccessful in this population.
- Trial name
- NCT01031433
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Use Disorder, Alcohol Drinking
Virtual Incentive Treatment for Alcohol
The overall objective of this program of research is to utilize phosphatidylethanol (PEth), a blood-based biomarker that can detect alcohol use for up to 28 days to deliver a feasible telehealth-based 26-week CM intervention.
- Conditions
- Alcohol Use Disorder, Alcohol Drinking, Alcohol Abuse, Alcohol Dependence
- Trial name
- VITA (NCT06265506)
- Testing
- Contingency Management, Computer Based Training for Cognitive Behavioral Therapy for AUD (CBT4CBT)
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Washington State University
Tobacco Use Disorder, Tobacco Dependence
Equitable Smoking Relapse Prevention
The goal of this clinical trial is to test a GPS (Global Positioning System)-enabled smartphone app (QuitBuddy) in current smokers.
- Trial name
- NCT05625685
- Testing
- Quitbuddy, Control, SDoH Augmentation
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bryan W. Heckman
Anorexia Nervosa
Characteristics of Intensity and Dependence to Physical Activity in Anorexia Nervosa
Etude d'épidémiologie clinique multicentrique (IMM), naturalistique, comparant un échantillon clinique à un échantillon de témoins issus de la population générale.
- Trial name
- HAP-AM (NCT02165982)
- Where
- France
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Institut Mutualiste Montsouris
Aging, Falling
Effectiveness of Online Exercise Training in Geriatric Population During COVID-19
The aim of this study is to investigate the effectiveness of online exercise training in geriatric population whose daily life activity level decreased during COVID-19 pandemic.
- Conditions
- Aging, Falling, Dependence, Inactivity, Physical
- Trial name
- NCT06548880
- Testing
- Structured exercise program
- Where
- Turkey (Türkiye)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medipol University
Patients Hospitalized in a FRC Department
Validation of a SOFMER Activity Scale
A person's dependency is defined as the total or partial inability to perform without helps the necessary activities of daily life due to activity limitations in the usual environment.
- Trial name
- SAS (NCT03116204)
- Testing
- Assessment of score SAS
- Where
- 9 sites in France
- Volunteers
- 152 people
- Sponsor
- Hospices Civils de Lyon
Chronic Pain, Opioid Dependency
Chronic Pain and Opioid Dependence Assessment and Treatment
This study involves the development of an integrated psychotherapy that addresses both chronic pain and opioid dependence(POD).
- Trial name
- CPODAT (NCT00727675)
- Testing
- Integrated Cognitive Behavioral Therapy
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Yale University
Frailty, Muscle Weakness
Effectiveness of Protein Supplementation on Frailty Improvement, Muscle Strength and Physical Performance Among Pre-Frail Elderly People
The goal of this randomized clinical trial is to study the effectiveness of protein supplements in frailty improvement, muscle strength, physical performance, energy intake and body composition of pre-frail elderly people.
- Conditions
- Frailty, Muscle Weakness, Physical Dependence, Weight Loss
- Trial name
- NCT05648617
- Testing
- SUSTINEX Hydrolyzed Whey Protein
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Cannabis Dependence, Harmful Use
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
Cannabis Abstinence and Neurocognitive Assessment in Adolescence
- Conditions
- Cannabis Dependence, Harmful Use, Cognitive Assessment
- Trial name
- CANAA (NCT07160153)
- Testing
- Neurocognitive assessment, Urine toxicological assessment
- Where
- Czechia
- Volunteers
- 29 people
- Sponsor
- University Hospital Pilsen
Cocaine Dependence, Substance Use Disorders
Longitudinal Assessment of Functional Connectivity in Treatment Engaged Cocaine Users
High-relapse rates to addiction are likely due to motivational (limbic) and cognitive (executive) factors. The purpose of this proposal is to determine the relationship between functional connectivity in executive control regions…
- Trial name
- NCT03554928
- Testing
- magnetic resonance imaging
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Medical University of South Carolina
Nicotine Dependence, Nicotine Withdrawal
Human Laboratory Study of Varenicline and Bupropion for Nicotine Dependence
The objective of this proposal is to elucidate effects of bupropion SR + varenicline on smoking-cessation related processes in early abstinence using a human laboratory model.
- Trial name
- ChanBan (NCT00749658)
- Testing
- Bupropion, Varenicline
- Where
- United States
- Volunteers
- 121 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Smoking, Cigarette, Smoking, Tobacco
Examination of Low Wattage and High Wattage E-Cigarettes
The overall aim of the proposed study is to evaluate the effect of switching from conventional cigarettes to either a LWe or HWe on smoking behavior, product use patterns and continued use, as well as biomarkers of toxicant…
- Conditions
- Smoking, Cigarette, Smoking, Tobacco, Nicotine Dependence, Exposure to Toxic Agent
- Trial name
- SWITCH (NCT03113136)
- Testing
- Low wattage E cigarette device, High wattage E cigarette device, Usual brand cigarette
- Where
- United States
- Volunteers
- 372 people, healthy volunteers welcome
- Sponsor
- Ohio State University Comprehensive Cancer Center
Narcotic Use, Postoperative Pain
A Prospective Assessment of Opioid Utilization Post-operatively in Sports Orthopaedic Surgeries
There was a study titled "A prospective evaluation of opioid utilization after upper extremity surgical procedures: Identifying consumption patterns and determining prescribing guidelines" by Dr.
- Conditions
- Narcotic Use, Postoperative Pain, Narcotic Abuse, Opioid Use
- Trial name
- Opioids (NCT03422211)
- Testing
- Questionnaire
- Where
- 3 sites in United States
- Volunteers
- 223 people
- Sponsor
- St. Louis University
Healthy Lifestyle Behaviors in High School Students
Promoting Healthy Lifestyle Behaviors in High School Students
Adolescence (ages 10-19) is a critical developmental stage in which individuals undergo significant physical, psychological, and social changes.
- Trial name
- NCT07244796
- Testing
- provide training
- Where
- Turkey (Türkiye)
- Volunteers
- 312 people, healthy volunteers welcome
- Sponsor
- Erzurum Technical University
Duchenne Muscular Dystrophy, Burden, Dependency
Your Voice; Impact of Duchenne Muscular Dystrophy (DMD) on the Lives of Families
The purpose of this study is to improve the understanding of the treatment goals that a person with Duchenne Muscular Dystrophy (DMD) or the caregiver may be most interested in, based on the severity of the person's disease.
- Conditions
- Duchenne Muscular Dystrophy, Burden, Dependency, Disability Physical, Disease Management
- Trial name
- NCT03680365
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Jett Foundation, Inc.